AU2002214170A1 - Process for the preparation of 1,5-disubstituted-3-amino-1,2,4-triazoles and substituted aminoguanidines as intermediate compounds - Google Patents

Process for the preparation of 1,5-disubstituted-3-amino-1,2,4-triazoles and substituted aminoguanidines as intermediate compounds

Info

Publication number
AU2002214170A1
AU2002214170A1 AU2002214170A AU1417002A AU2002214170A1 AU 2002214170 A1 AU2002214170 A1 AU 2002214170A1 AU 2002214170 A AU2002214170 A AU 2002214170A AU 1417002 A AU1417002 A AU 1417002A AU 2002214170 A1 AU2002214170 A1 AU 2002214170A1
Authority
AU
Australia
Prior art keywords
triazoles
disubstituted
amino
preparation
intermediate compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002214170A
Other languages
English (en)
Inventor
Sandor Bokotey
Eva Csikos
Csaba Gonczi
Felix Hajdu
Gergely Heja
Istvan Hermecz
Benjamin Podanyi
Dipl. Chem. Eng. Andrea Santane Csutor
Tiborne Szomor
Gyorgyne Szvoboda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo SA filed Critical Sanofi Synthelabo SA
Publication of AU2002214170A1 publication Critical patent/AU2002214170A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/14—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/56—Ring systems containing bridged rings
    • C07C2603/58—Ring systems containing bridged rings containing three rings
    • C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
    • C07C2603/74—Adamantanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2002214170A 2000-10-26 2001-10-25 Process for the preparation of 1,5-disubstituted-3-amino-1,2,4-triazoles and substituted aminoguanidines as intermediate compounds Abandoned AU2002214170A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
HUP0004154 2000-10-26
HU0004154A HUP0004154A3 (en) 2000-10-26 2000-10-26 Process for the preparation of 1,5-disubstituted-3-amino-1,2,4-triazole derivatives
PCT/HU2001/000103 WO2002034729A1 (en) 2000-10-26 2001-10-25 Process for the preparation of 1,5-disubstituted-3-amino-1,2,4-triazoles and substituted aminoguanidines as intermediate compounds

Publications (1)

Publication Number Publication Date
AU2002214170A1 true AU2002214170A1 (en) 2002-05-06

Family

ID=89978699

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002214170A Abandoned AU2002214170A1 (en) 2000-10-26 2001-10-25 Process for the preparation of 1,5-disubstituted-3-amino-1,2,4-triazoles and substituted aminoguanidines as intermediate compounds

Country Status (14)

Country Link
US (1) US20040039203A1 (enExample)
EP (1) EP1337519A1 (enExample)
JP (1) JP2004512329A (enExample)
CN (1) CN1471516A (enExample)
AU (1) AU2002214170A1 (enExample)
BR (1) BR0114828A (enExample)
CA (1) CA2427045A1 (enExample)
CZ (1) CZ20031437A3 (enExample)
HR (1) HRP20030424A2 (enExample)
HU (1) HUP0004154A3 (enExample)
MX (1) MXPA03003506A (enExample)
PL (1) PL360786A1 (enExample)
SK (1) SK5112003A3 (enExample)
WO (1) WO2002034729A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN121969609A (zh) * 2023-07-25 2026-05-01 Pi工业有限公司 制备1-烷基-1h-1,2,4-三唑-3-胺化合物的方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH530964A (de) * 1964-05-05 1972-11-30 Wander Ag Dr A Verfahren zur Herstellung von Phenylalkylaminoguanidinen
CH530965A (de) * 1964-05-05 1972-11-30 Wander Ag Dr A Verfahren zur Herstellung von 2,6-Dihalogen-phenylalkylaminoguanidinen
CH533603A (de) * 1966-06-02 1973-02-15 Wander Ag Dr A Verfahren zur Herstellung von Phenylalkylaminoguanidinen
FR1537892A (fr) * 1966-07-21 1968-08-30 British Petroleum Co Composition de lubrifiant synthétique
US3515723A (en) * 1967-11-14 1970-06-02 Merck & Co Inc 2 - (5 - amino - 1h - 1,2,4 - triazol - 3 - yl)- 3-aminopyrazines and processes for their preparation
US3541218A (en) * 1969-06-18 1970-11-17 Lilly Co Eli Omicron-fluorobenzylaminoguanidine for diabetes
US3541217A (en) * 1969-06-30 1970-11-17 Lilly Co Eli Omicron-chlorobenzylaminoguanidine for treating bovine ketosis
US3714363A (en) * 1970-08-11 1973-01-30 Sandoz Ag Substituted amino guanidine as anti-diabetic agents
DE4321109C2 (de) * 1993-06-25 1998-01-29 Sanol Arznei Schwarz Gmbh Pharmakologisch aktive Verbindungen mit Nitrosohydrazinpartialstruktur
US5994577A (en) * 1994-11-23 1999-11-30 Larsen; Scott D. Aminoguanidine carboxylates for the treatment of non-insulin-dependent diabetes mellitus
US6268398B1 (en) * 1998-04-24 2001-07-31 Mitokor Compounds and methods for treating mitochondria-associated diseases

Also Published As

Publication number Publication date
MXPA03003506A (es) 2004-05-04
HUP0004154A3 (en) 2003-11-28
WO2002034729A1 (en) 2002-05-02
US20040039203A1 (en) 2004-02-26
SK5112003A3 (en) 2004-01-08
WO2002034729A8 (en) 2004-04-08
HUP0004154A2 (hu) 2002-11-28
BR0114828A (pt) 2003-10-28
CN1471516A (zh) 2004-01-28
CZ20031437A3 (cs) 2004-10-13
HRP20030424A2 (en) 2005-10-31
HU0004154D0 (enExample) 2001-01-29
EP1337519A1 (en) 2003-08-27
CA2427045A1 (en) 2002-05-02
JP2004512329A (ja) 2004-04-22
PL360786A1 (en) 2004-09-20

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