AU2001297988B2 - Nucleic acid adjuvants - Google Patents

Nucleic acid adjuvants Download PDF

Info

Publication number
AU2001297988B2
AU2001297988B2 AU2001297988A AU2001297988A AU2001297988B2 AU 2001297988 B2 AU2001297988 B2 AU 2001297988B2 AU 2001297988 A AU2001297988 A AU 2001297988A AU 2001297988 A AU2001297988 A AU 2001297988A AU 2001297988 B2 AU2001297988 B2 AU 2001297988B2
Authority
AU
Australia
Prior art keywords
composition
nucleic acid
antigen
subunit
dna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2001297988A
Other languages
English (en)
Other versions
AU2001297988A1 (en
Inventor
Joshua E. Arrington
Joel R. Haynes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Powderject Vaccines Inc
Original Assignee
Powderject Vaccines Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Powderject Vaccines Inc filed Critical Powderject Vaccines Inc
Publication of AU2001297988A1 publication Critical patent/AU2001297988A1/en
Application granted granted Critical
Publication of AU2001297988B2 publication Critical patent/AU2001297988B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55544—Bacterial toxins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2001297988A 2000-11-27 2001-11-26 Nucleic acid adjuvants Ceased AU2001297988B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US72431500A 2000-11-27 2000-11-27
US09/724,315 2000-11-27
PCT/US2001/043151 WO2003004055A2 (en) 2000-11-27 2001-11-26 Nucleic acid adjuvants

Publications (2)

Publication Number Publication Date
AU2001297988A1 AU2001297988A1 (en) 2003-05-22
AU2001297988B2 true AU2001297988B2 (en) 2006-10-26

Family

ID=24909936

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001297988A Ceased AU2001297988B2 (en) 2000-11-27 2001-11-26 Nucleic acid adjuvants

Country Status (16)

Country Link
EP (1) EP1379273B1 (https=)
JP (1) JP4221289B2 (https=)
KR (1) KR20040045391A (https=)
CN (1) CN1317034C (https=)
AT (1) ATE442858T1 (https=)
AU (1) AU2001297988B2 (https=)
BR (1) BR0115646A (https=)
CA (1) CA2429708A1 (https=)
DE (1) DE60139959D1 (https=)
DK (1) DK1379273T3 (https=)
ES (1) ES2332261T3 (https=)
IL (2) IL156041A0 (https=)
MX (1) MXPA03004638A (https=)
NZ (1) NZ526175A (https=)
PT (1) PT1379273E (https=)
WO (1) WO2003004055A2 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005035771A2 (en) 2003-10-10 2005-04-21 Powderject Vaccines, Inc. Nucleic acid constructs
AU2005212479B2 (en) 2004-02-11 2009-09-10 Msd Italia S.R.L. Carcinoembryonic antigen fusion proteins and uses thereof
GB0507997D0 (en) * 2005-02-01 2005-05-25 Powderject Vaccines Inc Nucleic acid constructs
US8389686B2 (en) 2008-05-07 2013-03-05 Osaka University Noncovalent collagen crosslinking agent
EP2616045B1 (en) 2010-09-15 2017-10-25 Randall J. Mrsny Systems and methods of delivery of bioactive agents using bacterial toxin-derived transport sequences
US11246915B2 (en) 2010-09-15 2022-02-15 Applied Molecular Transport Inc. Cholix toxin-derived fusion molecules for oral delivery of biologically active cargo
CN103060253A (zh) * 2013-01-24 2013-04-24 麻丽丹 霍乱弧菌ctxAB基因的质粒克隆菌株以及制备方法和应用
PL3139965T3 (pl) 2014-05-07 2022-01-31 Applied Molecular Transport Inc. Cząsteczki fuzyjne pochodzące z toksyny cholix do doustnego dostarczania ładunku biologicznie czynnego
EP4082558B1 (en) 2018-03-08 2023-08-23 Applied Molecular Transport Inc. Toxin-derived delivery constructs for oral delivery
KR20210110294A (ko) 2018-11-07 2021-09-07 어플라이드 몰레큘라 트랜스포트 인크. 통과세포외배출용 전달 구조체 및 관련 방법
CN114599665A (zh) 2019-08-16 2022-06-07 应用分子转运公司 组合物、制剂及白细胞介素产生和纯化

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5219740A (en) 1987-02-13 1993-06-15 Fred Hutchinson Cancer Research Center Retroviral gene transfer into diploid fibroblasts for gene therapy
TW404844B (en) 1993-04-08 2000-09-11 Oxford Biosciences Ltd Needleless syringe
GB9416663D0 (en) 1994-08-17 1994-10-12 Oxford Bioscience Limited Particle delivery
CA2199417C (en) 1994-10-24 2008-07-08 Brian John Bellhouse Particle delivery
GB9426379D0 (en) 1994-12-23 1995-03-01 Oxford Biosciences Ltd Particle delivery
US6056960A (en) * 1995-06-07 2000-05-02 Kaslow; Harvey R. Compositions exhibiting ADP-ribosyltransferase activity and methods for the preparation and use thereof
GB9612629D0 (en) 1996-06-17 1996-08-21 Oxford Biosciences Ltd Method for providing dense particle compositions for use in transdermal particle delivery
US5980898A (en) * 1996-11-14 1999-11-09 The United States Of America As Represented By The U.S. Army Medical Research & Material Command Adjuvant for transcutaneous immunization

Also Published As

Publication number Publication date
JP2004536107A (ja) 2004-12-02
EP1379273B1 (en) 2009-09-16
WO2003004055A2 (en) 2003-01-16
PT1379273E (pt) 2009-11-27
WO2003004055A3 (en) 2003-11-20
ATE442858T1 (de) 2009-10-15
DK1379273T3 (da) 2009-11-09
CN1537013A (zh) 2004-10-13
BR0115646A (pt) 2005-12-13
ES2332261T3 (es) 2010-02-01
JP4221289B2 (ja) 2009-02-12
NZ526175A (en) 2006-01-27
IL156041A (en) 2010-05-17
CA2429708A1 (en) 2003-01-16
EP1379273A2 (en) 2004-01-14
KR20040045391A (ko) 2004-06-01
IL156041A0 (en) 2003-12-23
DE60139959D1 (de) 2009-10-29
MXPA03004638A (es) 2004-04-20
CN1317034C (zh) 2007-05-23

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired