AU2001261624A1 - Modulation of t-cell receptor interactions - Google Patents
Modulation of t-cell receptor interactionsInfo
- Publication number
- AU2001261624A1 AU2001261624A1 AU2001261624A AU6162401A AU2001261624A1 AU 2001261624 A1 AU2001261624 A1 AU 2001261624A1 AU 2001261624 A AU2001261624 A AU 2001261624A AU 6162401 A AU6162401 A AU 6162401A AU 2001261624 A1 AU2001261624 A1 AU 2001261624A1
- Authority
- AU
- Australia
- Prior art keywords
- tcr
- molecule
- mhc
- ofthe
- mhc antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
- G01N33/505—Cells of the immune system involving T-cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
- G01N2333/70539—MHC-molecules, e.g. HLA-molecules
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
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- General Physics & Mathematics (AREA)
- Transplantation (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Steroid Compounds (AREA)
- Oscillators With Electromechanical Resonators (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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| US20692000P | 2000-05-25 | 2000-05-25 | |
| US60206920 | 2000-05-25 | ||
| PCT/US2001/015699 WO2001090747A2 (fr) | 2000-05-25 | 2001-05-16 | Modulation des interactions des recepteurs des cellules t |
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| AU2001261624A1 true AU2001261624A1 (en) | 2001-12-03 |
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| AU2001261624A Abandoned AU2001261624A1 (en) | 2000-05-25 | 2001-05-16 | Modulation of t-cell receptor interactions |
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| US (1) | US20040253632A1 (fr) |
| EP (1) | EP1287363A2 (fr) |
| JP (1) | JP2004501364A (fr) |
| CN (1) | CN1430728A (fr) |
| AU (1) | AU2001261624A1 (fr) |
| CA (1) | CA2410642A1 (fr) |
| WO (1) | WO2001090747A2 (fr) |
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| JP4447456B2 (ja) | 2001-06-05 | 2010-04-07 | アルトール バイオサイエンス コーポレーション | Ｐ５３結合ｔ細胞受容体分子とその使用 |
| US20040072262A1 (en) * | 2002-10-11 | 2004-04-15 | Montero-Julian Felix A. | Methods and systems for detecting MHC class I binding peptides |
| AU2002953533A0 (en) * | 2002-12-24 | 2003-01-16 | Arthron Limited | Fc receptor modulating compounds and compositions |
| DE602004030125D1 (de) * | 2003-07-22 | 2010-12-30 | Beckman Coulter Inc | Verfahren zum nachweis der aktivierung von t-zellen durch mhc-bindende peptide |
| EP1692504A4 (fr) * | 2003-11-03 | 2007-06-27 | Beckman Coulter Inc | Procedes a base de solutions de detection de peptides se fixant au cmh |
| AU2004289316B2 (en) | 2003-11-10 | 2011-03-31 | Altor Bioscience Corporation | Soluble TCR molecules and methods of use |
| US20050287611A1 (en) * | 2004-05-07 | 2005-12-29 | Nugent C T Iv | MHC bridging system for detecting CTL-mediated lysis of antigen presenting cells |
| WO2006009838A2 (fr) | 2004-06-17 | 2006-01-26 | Beckman Coulter, Inc. | Epitopes de mycobacterium tuberculosis et leurs procedes d'utilisation |
| CA2631291A1 (fr) * | 2005-12-08 | 2007-06-14 | Laboratoires Serono S.A. | Pyrimidylhydrazones et pyrimidylhydrazones fusionnees antiproliferatives |
| US20070243575A1 (en) * | 2006-02-06 | 2007-10-18 | The Scripps Research Institute | Compositions and methods for treatment of immune-related disease |
| WO2008116468A2 (fr) | 2007-03-26 | 2008-10-02 | Dako Denmark A/S | Complexes peptidiques du cmh et leurs utilisations dans des maladies infectieuses |
| EP3620465A1 (fr) | 2007-07-03 | 2020-03-11 | Dako Denmark A/S | Procédés améliorés pour produire, marquer et utiliser des multimères du cmh |
| EP2197908A2 (fr) | 2007-09-27 | 2010-06-23 | Dako Denmark A/S | Multimères cmh dans le diagnostic, le vaccin et le traitement de la tuberculose |
| US10968269B1 (en) | 2008-02-28 | 2021-04-06 | Agilent Technologies, Inc. | MHC multimers in borrelia diagnostics and disease |
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| EP2258719A1 (fr) * | 2009-05-19 | 2010-12-08 | Max-Delbrück-Centrum für Molekulare Medizin (MDC) | Récepteur de lymphocyte T à cibles multiples |
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| JP6304594B2 (ja) * | 2014-05-29 | 2018-04-04 | 国立大学法人千葉大学 | 芳香環含有化合物並びに癌の予防剤および／または治療剤 |
| CN107995926B (zh) * | 2014-12-19 | 2021-07-06 | 苏黎世联邦理工学院 | 嵌合抗原受体和使用方法 |
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| AU2017266905B2 (en) | 2016-05-18 | 2022-12-15 | Albert Einstein College Of Medicine, Inc. | Variant PD-L1 polypeptides, T-cell modulatory multimeric polypeptides, and methods of use thereof |
| US11827688B2 (en) | 2016-06-02 | 2023-11-28 | Immunocore Limited | Dosing regimen for GP100-specific TCR—anti-CD3 SCFV fusion protein |
| DK3558339T3 (da) | 2016-12-22 | 2024-02-26 | Cue Biopharma Inc | T-celle-modulerende multimere polypeptider og fremgangsmåder til anvendelse deraf |
| EP3565829A4 (fr) | 2017-01-09 | 2021-01-27 | Cue Biopharma, Inc. | Polypeptides multimères modulateurs de lymphocytes t et leurs procédés d'utilisation |
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| US20190004063A1 (en) * | 2017-06-30 | 2019-01-03 | Indiana University Research & Technology Corporation | Compositions and methods for detecting sla reactivity |
| WO2019139896A1 (fr) | 2018-01-09 | 2019-07-18 | Cue Biopharma, Inc. | Polypeptides multimères modulateurs de lymphocytes t et leurs procédés d'utilisation |
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| WO2023196995A1 (fr) * | 2022-04-07 | 2023-10-12 | Repertoire Immune Medicines, Inc. | Multimères de récepteurs de cellules t et leurs utilisations |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5734023A (en) * | 1991-11-19 | 1998-03-31 | Anergen Inc. | MHC class II β chain/peptide complexes useful in ameliorating deleterious immune responses |
| US6399368B1 (en) * | 1992-01-17 | 2002-06-04 | Board Of Regents, The University Of Texas System | Secretion of T cell receptor fragments from recombinant Escherichia coli cells |
| JPH10503379A (ja) * | 1994-07-29 | 1998-03-31 | デイド・インターナショナル・インコーポレーテッド | Ｍｈｃ複合体およびその用途 |
| GB9509844D0 (en) * | 1995-05-16 | 1995-07-12 | Cancer Res Campaign Tech | Screening for inhibitors of TCR-MHC interactions |
| US5869270A (en) * | 1996-01-31 | 1999-02-09 | Sunol Molecular Corporation | Single chain MHC complexes and uses thereof |
| EP0937258A2 (fr) * | 1996-10-29 | 1999-08-25 | Fred Hutchinson Cancer Research Center, Inc. | Gene de classe i du complexe majeur d'histocompatibilite humain a stress cellulaire regule |
| EP1066380B1 (fr) * | 1998-05-19 | 2001-11-14 | Avidex Ltd | Recepteur de lymphocyte t soluble |
| US6245332B1 (en) * | 1999-01-15 | 2001-06-12 | The Board Of Trustees Of The Leland Stanford Junior University | Modulation of systemic memory T cell trafficking |
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- 2001-05-16 WO PCT/US2001/015699 patent/WO2001090747A2/fr active Application Filing
- 2001-05-16 US US09/859,012 patent/US20040253632A1/en not_active Abandoned
- 2001-05-16 EP EP01935537A patent/EP1287363A2/fr not_active Withdrawn
- 2001-05-16 CN CN01810020A patent/CN1430728A/zh active Pending
- 2001-05-16 CA CA002410642A patent/CA2410642A1/fr not_active Abandoned
- 2001-05-16 JP JP2001586462A patent/JP2004501364A/ja active Pending
- 2001-05-16 AU AU2001261624A patent/AU2001261624A1/en not_active Abandoned
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|---|---|
| CA2410642A1 (fr) | 2001-11-29 |
| WO2001090747A2 (fr) | 2001-11-29 |
| WO2001090747A3 (fr) | 2002-07-11 |
| EP1287363A2 (fr) | 2003-03-05 |
| JP2004501364A (ja) | 2004-01-15 |
| US20040253632A1 (en) | 2004-12-16 |
| CN1430728A (zh) | 2003-07-16 |
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