DE602004030125D1 - Verfahren zum nachweis der aktivierung von t-zellen durch mhc-bindende peptide - Google Patents

Verfahren zum nachweis der aktivierung von t-zellen durch mhc-bindende peptide

Info

Publication number
DE602004030125D1
DE602004030125D1 DE602004030125T DE602004030125T DE602004030125D1 DE 602004030125 D1 DE602004030125 D1 DE 602004030125D1 DE 602004030125 T DE602004030125 T DE 602004030125T DE 602004030125 T DE602004030125 T DE 602004030125T DE 602004030125 D1 DE602004030125 D1 DE 602004030125D1
Authority
DE
Germany
Prior art keywords
cells
mhc
detecting
activation
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602004030125T
Other languages
English (en)
Inventor
Jennie Chyan Chuu Chang
Suha Kasey
Veronique Trigueros Crebassa
Felix A Montero-Julian
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beckman Coulter Inc
Original Assignee
Beckman Coulter Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beckman Coulter Inc filed Critical Beckman Coulter Inc
Publication of DE602004030125D1 publication Critical patent/DE602004030125D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G01N33/505—Cells of the immune system involving T-cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56977—HLA or MHC typing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DE602004030125T 2003-07-22 2004-07-22 Verfahren zum nachweis der aktivierung von t-zellen durch mhc-bindende peptide Active DE602004030125D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48935903P 2003-07-22 2003-07-22
PCT/US2004/023898 WO2005010026A2 (en) 2003-07-22 2004-07-22 Methods for detecting activation of t-cells by mhc binding peptides

Publications (1)

Publication Number Publication Date
DE602004030125D1 true DE602004030125D1 (de) 2010-12-30

Family

ID=34102856

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004030125T Active DE602004030125D1 (de) 2003-07-22 2004-07-22 Verfahren zum nachweis der aktivierung von t-zellen durch mhc-bindende peptide

Country Status (4)

Country Link
EP (1) EP1648919B1 (de)
AT (1) ATE488767T1 (de)
DE (1) DE602004030125D1 (de)
WO (1) WO2005010026A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040072262A1 (en) 2002-10-11 2004-04-15 Montero-Julian Felix A. Methods and systems for detecting MHC class I binding peptides
JP5224477B2 (ja) * 2006-11-01 2013-07-03 ベックマン コールター， インコーポレイテッド 親和性アッセイのための結合表面
FR2992427A1 (fr) * 2012-06-20 2013-12-27 Assist Publ Hopitaux De Paris Methode de pronostic d'un lymphome et kit pour sa mise en oeuvre
EP3182125A1 (de) * 2015-12-16 2017-06-21 Ab Tcer T-zellreaktivitätsplattform
US11360079B2 (en) 2015-12-16 2022-06-14 Neogap Therapeutics Ab T-cell reactivity platform
JP7329439B2 (ja) * 2016-05-13 2023-08-18 エムビーエル インターナショナル コーポレイション ペプチド交換システムおよび方法
CN109963584B (zh) * 2016-09-06 2024-03-15 豪夫迈·罗氏有限公司 结合mhc的肽阵列及其使用方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5635363A (en) 1995-02-28 1997-06-03 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for the detection, quantitation and purification of antigen-specific T cells
WO2001090747A2 (en) * 2000-05-25 2001-11-29 Sunol Molecular Corporation Modulation of t-cell receptor interactions
CA2440474A1 (en) * 2001-04-05 2002-10-17 Virginia Mason Research Center Methods of mhc class ii epitope mapping, detection of autoimmune t cells and antigens, and autoimmune treatment
US20030044389A1 (en) * 2001-07-02 2003-03-06 Brown Patrick O. Microarrays for cell phenotyping and manipulation
US20040248205A1 (en) * 2003-04-16 2004-12-09 Stern Lawrence J. Major histocompatibility complex (MHC)-peptide arrays

Also Published As

Publication number Publication date
ATE488767T1 (de) 2010-12-15
WO2005010026A3 (en) 2005-06-02
WO2005010026A2 (en) 2005-02-03
EP1648919A4 (de) 2007-08-01
EP1648919A2 (de) 2006-04-26
EP1648919B1 (de) 2010-11-17

Similar Documents

Publication Publication Date Title
WO2004034033A3 (en) Methods and systems for detecting mhc class i and class ii binding peptides
DE50301487D1 (de) Reaktionsgefäss zur durchführung von array-verfahren
DK1786927T3 (da) Indretning og fremgangsmåde til påvisning af ladede makromolekyler
ATE477338T1 (de) Vorrichtung und verfahren zum nachweis von molekularen wechselwirkungen
ATE480772T1 (de) Verfahren zum akustischen ausgeben einer information in einem analysesystem
BRPI0515079A (pt) marcadores imobilizados e métodos de detecção de prions conformacionalmente alterados
ATE404999T1 (de) Verfahren zur überwachung des betriebszustandes eines brennstoffzellenstapels
ATE416376T1 (de) Analysegeräte, biosensoren und verfahren
DK1869475T3 (da) In vitro metode til samtidig detektering og identifikation af antibiotika i forskellige klasser og et tilsvarende diagnosekit
WO2003100413A3 (en) Surface acoustic wave sensors and methods for detecting target analytes
DE602004030125D1 (de) Verfahren zum nachweis der aktivierung von t-zellen durch mhc-bindende peptide
DE502005004900D1 (de) Trägerplatte zur durchführung funktioneller tests an biologischen zellen sowie verfahren zur beschichtung der trägerplatte
DE59606675D1 (de) Verfahren zum nachweis von telomerase-aktivität
ATE377753T1 (de) Nachweis von dna-bindungsproteinen
ATE466283T1 (de) Zentrifugalvorrichtung und verfahren zur durchführung von bindungsversuchen
ATE354635T1 (de) Substrat und verfahren zum messen elektrophysiologischer eigenschaften von zellmembranen
ATE533053T1 (de) Nicht-elispot-test
DE50207025D1 (de) Verfahren zum Nachweis und zur Isolierung von T-Lymphozyten, die ein definiertes Antigen erkennen
DE50207801D1 (de) Verfahren zum Nachweis prokaryontischer DNA
DK1664747T3 (da) Fremgangsmåde og indretning til påvisning af meget små partikelmængder
ATE465276T1 (de) Quantitativer test zum nachweis neu synthetisierter rna in einem zellfreien system sowie identifizierung von inhibitoren der rna- synthese
ATE528640T1 (de) Detektionssysteme und -verfahren für flüssigkeitsgekoppelte defekte
ATE340998T1 (de) Verfahren zur bestimmung von flüchtigen substanzen in lösung
DE602004013942D1 (de) Ialien
DE50210523D1 (de) Verfahren zur identifizierung von zielepitopen der t-zell-vermittelten immunantwort und zum nachweis epitop-spezifischer t-zellen