ATE354635T1 - Substrat und verfahren zum messen elektrophysiologischer eigenschaften von zellmembranen - Google Patents

Substrat und verfahren zum messen elektrophysiologischer eigenschaften von zellmembranen

Info

Publication number
ATE354635T1
ATE354635T1 AT03722763T AT03722763T ATE354635T1 AT E354635 T1 ATE354635 T1 AT E354635T1 AT 03722763 T AT03722763 T AT 03722763T AT 03722763 T AT03722763 T AT 03722763T AT E354635 T1 ATE354635 T1 AT E354635T1
Authority
AT
Austria
Prior art keywords
substrate
electrophysiological properties
cell membranes
measuring electrophysiological
cell membrane
Prior art date
Application number
AT03722763T
Other languages
English (en)
Inventor
Ras Kaas Vestergaard
Niels Willumsen
Nicholas Oswald
Jonatan Kutchinsky
Dirk Reuter
Rafael Taboryski
Original Assignee
Sophion Bioscience As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0303922A external-priority patent/GB2398635A/en
Application filed by Sophion Bioscience As filed Critical Sophion Bioscience As
Application granted granted Critical
Publication of ATE354635T1 publication Critical patent/ATE354635T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48728—Investigating individual cells, e.g. by patch clamp, voltage clamp

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
AT03722763T 2002-04-17 2003-04-17 Substrat und verfahren zum messen elektrophysiologischer eigenschaften von zellmembranen ATE354635T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37279602P 2002-04-17 2002-04-17
GB0303922A GB2398635A (en) 2003-02-21 2003-02-21 A substrate providing a cell gigaseal for a patch clamp

Publications (1)

Publication Number Publication Date
ATE354635T1 true ATE354635T1 (de) 2007-03-15

Family

ID=29252469

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03722763T ATE354635T1 (de) 2002-04-17 2003-04-17 Substrat und verfahren zum messen elektrophysiologischer eigenschaften von zellmembranen

Country Status (10)

Country Link
US (1) US20050212095A1 (de)
EP (1) EP1495105B1 (de)
JP (1) JP4351073B2 (de)
CN (1) CN100506969C (de)
AT (1) ATE354635T1 (de)
AU (1) AU2003229926A1 (de)
CA (1) CA2480338C (de)
DE (1) DE60311973T2 (de)
DK (1) DK1495105T3 (de)
WO (1) WO2003089564A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7244349B2 (en) 1997-12-17 2007-07-17 Molecular Devices Corporation Multiaperture sample positioning and analysis system
US20020144905A1 (en) 1997-12-17 2002-10-10 Christian Schmidt Sample positioning and analysis system
US7270730B2 (en) 2000-08-04 2007-09-18 Essen Instruments, Inc. High-throughput electrophysiological measurement system
US7067046B2 (en) 2000-08-04 2006-06-27 Essen Instruments, Inc. System for rapid chemical activation in high-throughput electrophysiological measurements
GB2398635A (en) 2003-02-21 2004-08-25 Sophion Bioscience As A substrate providing a cell gigaseal for a patch clamp
JP4386835B2 (ja) 2002-08-21 2009-12-16 セレクトリコン アーベー パッチクランプ記録において高抵抗固着を獲得して維持するシステム及び方法
EP1801586B1 (de) * 2002-08-21 2010-10-13 Cellectricon Ab System zur Gewinnung und Erhaltung hochresistenter Verschlüsse bei Patch-Clamp-Aufzeichnungen
WO2007108773A1 (en) * 2006-03-23 2007-09-27 Agengy For Science, Technology And Research Device for analyzing the status of a particle
US8071363B2 (en) * 2006-05-25 2011-12-06 Panasonic Corporation Chip for cell electrophysiological sensor, cell electrophysiological sensor using the same, and manufacturing method of chip for cell electrophysiological sensor
CN1987459B (zh) * 2006-12-14 2012-07-18 上海交通大学 生物传感器的制作方法
JP4868067B2 (ja) * 2008-08-04 2012-02-01 パナソニック株式会社 細胞電気生理センサ用チップとこれを用いた細胞電気生理センサ、および細胞電気生理センサ用チップの製造方法
WO2010122293A1 (en) * 2009-04-20 2010-10-28 Oxford Nanopore Technologies Limited Lipid bilayer sensor array
KR101119381B1 (ko) * 2009-06-18 2012-03-07 한국과학기술원 세포 특성 측정 장치 및 시스템과 이를 이용한 세포 특성 측정 방법
JP5159808B2 (ja) * 2010-02-09 2013-03-13 日本電信電話株式会社 脂質二分子膜基板
US20130136673A1 (en) 2010-07-09 2013-05-30 Sophion Bioscience A/S Chip assembly for use in a microfluidic analysis sytem
WO2012117029A1 (en) 2011-03-01 2012-09-07 Sophion Bioscience A/S Handheld device for electrophysiological analysis
JP6037717B2 (ja) * 2011-12-20 2016-12-07 国立研究開発法人科学技術振興機構 プレーナーパッチクランプ装置、該装置用電極部及び細胞イオンチャンネル電流計測方法
DE102013007295B4 (de) * 2013-04-26 2015-06-25 Universität Rostock Elektrophysiologische Messanordnung und elektrophysiologisches Messverfahren
DE102014203280B4 (de) * 2014-02-24 2015-12-17 Cytocentrics Bioscience Gmbh Vorrichtung zur Bestimmung von Messgrößen an Membranen
JP7436991B2 (ja) * 2021-02-24 2024-02-22 日本電信電話株式会社 脂質相分離ドメイン形成基板及びその製造方法、並びに、脂質相分離ドメイン形成用の基板

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE29721359U1 (de) * 1997-12-03 1998-02-12 Deutsche Itt Industries Gmbh, 79108 Freiburg Vorrichtung zum Messen physiologischer Parameter
US6758961B1 (en) * 1997-12-17 2004-07-06 Ecole Polytechnique Federale De Lausanne Positioning and electrophysiological characterization of individual cells and reconstituted membrane systems on microstructured carriers
JP2003500065A (ja) * 1999-05-21 2003-01-07 ジェームス ジェイ． ヒックマン 高スループット機能ゲノム学
DE60025929T2 (de) * 1999-10-01 2006-11-09 Sophion Bioscience A/S Anordnung und verfahren zum feststellen und/oder überwachen elektrophysiologischer eigenschaften von ionenkanälen
GB9930718D0 (en) * 1999-12-24 2000-02-16 Central Research Lab Ltd Apparatus for and method of making electrical measurements on objects

Also Published As

Publication number Publication date
EP1495105A1 (de) 2005-01-12
AU2003229926A1 (en) 2003-11-03
CA2480338C (en) 2009-07-07
WO2003089564A1 (en) 2003-10-30
JP2005523011A (ja) 2005-08-04
DE60311973T2 (de) 2007-10-31
CN100506969C (zh) 2009-07-01
US20050212095A1 (en) 2005-09-29
CN1646679A (zh) 2005-07-27
DK1495105T3 (da) 2007-06-04
EP1495105B1 (de) 2007-02-21
DE60311973D1 (de) 2007-04-05
CA2480338A1 (en) 2003-10-30
JP4351073B2 (ja) 2009-10-28

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