AU2001260528A1 - Hygromycin a derivatives for the treatment of bacterial and protozoal infections - Google Patents

Hygromycin a derivatives for the treatment of bacterial and protozoal infections

Info

Publication number
AU2001260528A1
AU2001260528A1 AU2001260528A AU6052801A AU2001260528A1 AU 2001260528 A1 AU2001260528 A1 AU 2001260528A1 AU 2001260528 A AU2001260528 A AU 2001260528A AU 6052801 A AU6052801 A AU 6052801A AU 2001260528 A1 AU2001260528 A1 AU 2001260528A1
Authority
AU
Australia
Prior art keywords
methyl
hydroxy
phenyl
chloro
aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001260528A
Other languages
English (en)
Inventor
Matthew Merrill Hayward
Takushi Kaneko
Robert Gerald Linde Ii
Michael Scott Visser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Products Inc
Original Assignee
Pfizer Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc filed Critical Pfizer Products Inc
Publication of AU2001260528A1 publication Critical patent/AU2001260528A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/203Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/14Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU2001260528A 2000-06-02 2001-05-25 Hygromycin a derivatives for the treatment of bacterial and protozoal infections Abandoned AU2001260528A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20902300P 2000-06-02 2000-06-02
US60209023 2000-06-02
PCT/IB2001/000946 WO2001092280A1 (en) 2000-06-02 2001-05-25 Hygromycin a derivatives for the treatment of bacterial and protozoal infections

Publications (1)

Publication Number Publication Date
AU2001260528A1 true AU2001260528A1 (en) 2001-12-11

Family

ID=22777009

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001260528A Abandoned AU2001260528A1 (en) 2000-06-02 2001-05-25 Hygromycin a derivatives for the treatment of bacterial and protozoal infections

Country Status (31)

Country Link
US (1) US6867230B2 (xx)
EP (1) EP1287011A1 (xx)
JP (1) JP2003535100A (xx)
KR (1) KR20030010655A (xx)
CN (1) CN1432019A (xx)
AP (1) AP2002002669A0 (xx)
AR (1) AR028667A1 (xx)
AU (1) AU2001260528A1 (xx)
BG (1) BG107265A (xx)
BR (1) BR0111242A (xx)
CA (1) CA2410643A1 (xx)
CZ (1) CZ20023859A3 (xx)
EA (1) EA200201167A1 (xx)
EC (1) ECSP014093A (xx)
EE (1) EE200200671A (xx)
GT (1) GT200100099A (xx)
HU (1) HUP0302263A2 (xx)
IL (1) IL152984A0 (xx)
IS (1) IS6618A (xx)
MA (1) MA26909A1 (xx)
MX (1) MXPA02011966A (xx)
NO (1) NO20025704D0 (xx)
OA (1) OA12277A (xx)
PA (1) PA8518101A1 (xx)
PE (1) PE20020334A1 (xx)
PL (1) PL359179A1 (xx)
SK (1) SK16612002A3 (xx)
SV (1) SV2002000474A (xx)
TN (1) TNSN01080A1 (xx)
UY (1) UY26741A1 (xx)
WO (1) WO2001092280A1 (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ570989A (en) 2002-05-16 2010-01-29 Sepracor Inc Amines that inhibit a mammalian anandamide transporter, and methods of use thereof
US20210275559A1 (en) * 2018-08-20 2021-09-09 Kim Lewis Hygromycin a compounds and methods of treating spirochete diseases
CU20180159A7 (es) * 2018-12-28 2020-10-20 Chengdu Olisynn Biotechnology Co Ltd Derivados de oligosacáridos sintéticos como vacuna contra la bordetella pertussis

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1234567A (en) * 1915-09-14 1917-07-24 Edward J Quigley Soft collar.
US2004123A (en) * 1934-02-15 1935-06-11 Jr Robert B Loibl Pest exterminator
EA004374B1 (ru) * 1998-05-04 2004-04-29 Пфайзер Продактс Инк. Производные 2"-деоксигигромицина
ATE317448T1 (de) * 1998-05-04 2006-02-15 Pfizer Prod Inc Verfahren zur herstellung einer zusammensetzung, die hygromycin a und epi-hygromycin enthält
PL348063A1 (en) * 1998-12-02 2002-05-06 Pfizer Prod Inc Hygromycin a derivatives as antibacterial agents
CA2389191A1 (en) * 1999-10-29 2001-05-03 Pfizer Products Inc. Hygromycin derivatives
US7654321B2 (en) * 2006-12-27 2010-02-02 Schlumberger Technology Corporation Formation fluid sampling apparatus and methods

Also Published As

Publication number Publication date
EE200200671A (et) 2004-08-16
EP1287011A1 (en) 2003-03-05
US20030045528A1 (en) 2003-03-06
CZ20023859A3 (cs) 2004-02-18
CN1432019A (zh) 2003-07-23
MXPA02011966A (es) 2003-04-22
PA8518101A1 (es) 2002-09-17
KR20030010655A (ko) 2003-02-05
JP2003535100A (ja) 2003-11-25
AR028667A1 (es) 2003-05-21
SK16612002A3 (sk) 2004-04-06
US6867230B2 (en) 2005-03-15
TNSN01080A1 (fr) 2005-11-10
NO20025704L (no) 2002-11-27
IS6618A (is) 2002-11-14
MA26909A1 (fr) 2004-12-20
ECSP014093A (es) 2002-01-25
BG107265A (bg) 2003-07-31
PE20020334A1 (es) 2002-04-30
BR0111242A (pt) 2003-06-03
CA2410643A1 (en) 2001-12-06
NO20025704D0 (no) 2002-11-27
OA12277A (en) 2006-05-11
AP2002002669A0 (en) 2002-12-31
EA200201167A1 (ru) 2003-06-26
HUP0302263A2 (hu) 2003-10-28
PL359179A1 (en) 2004-08-23
IL152984A0 (en) 2003-06-24
WO2001092280A1 (en) 2001-12-06
UY26741A1 (es) 2001-12-28
GT200100099A (es) 2002-01-31
SV2002000474A (es) 2002-07-03

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