CU20180159A7 - Derivados de oligosacáridos sintéticos como vacuna contra la bordetella pertussis - Google Patents
Derivados de oligosacáridos sintéticos como vacuna contra la bordetella pertussisInfo
- Publication number
- CU20180159A7 CU20180159A7 CU2018000159A CU20180159A CU20180159A7 CU 20180159 A7 CU20180159 A7 CU 20180159A7 CU 2018000159 A CU2018000159 A CU 2018000159A CU 20180159 A CU20180159 A CU 20180159A CU 20180159 A7 CU20180159 A7 CU 20180159A7
- Authority
- CU
- Cuba
- Prior art keywords
- bordetella pertussis
- synthetic
- oligosaccharids
- derivatives
- vaccine against
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/099—Bordetella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/18—Acyclic radicals, substituted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/543—Mucosal route intranasal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6081—Albumin; Keyhole limpet haemocyanin [KLH]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
Abstract
<p>La presente invención proporciona fragmentos de oligosacáridos sintéticos provenientes del pentasacárido terminal del lipooligosacárido de Bordetella pertussis, un método para obtener los fragmentos de oligosacáridos sintéticos y los conjugados a partir de los mismos. También proporciona las composiciones vacunales que contienen tales glicoconjugados y que inducen una respuesta inmune capaz de reducir la colonización nasofaríngea de Bordetella pertussis.</p>
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CU2018000159A CU20180159A7 (es) | 2018-12-28 | 2018-12-28 | Derivados de oligosacáridos sintéticos como vacuna contra la bordetella pertussis |
CN201980000706.9A CN111819184B (zh) | 2018-12-28 | 2019-04-08 | 合成寡糖衍生物作为抗博德特百日咳杆菌疫苗 |
PCT/CU2019/050001 WO2020135898A1 (es) | 2018-12-28 | 2019-04-08 | Derivados de oligosacáridos sintéticos como vacuna contra bordetella pertussis |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CU2018000159A CU20180159A7 (es) | 2018-12-28 | 2018-12-28 | Derivados de oligosacáridos sintéticos como vacuna contra la bordetella pertussis |
Publications (1)
Publication Number | Publication Date |
---|---|
CU20180159A7 true CU20180159A7 (es) | 2020-10-20 |
Family
ID=66793711
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CU2018000159A CU20180159A7 (es) | 2018-12-28 | 2018-12-28 | Derivados de oligosacáridos sintéticos como vacuna contra la bordetella pertussis |
Country Status (3)
Country | Link |
---|---|
CN (1) | CN111819184B (es) |
CU (1) | CU20180159A7 (es) |
WO (1) | WO2020135898A1 (es) |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EA200201167A1 (ru) * | 2000-06-02 | 2003-06-26 | Пфайзер Продактс Инк. | Производные гигромицина а для лечения бактериальных и протозойных инфекций |
WO2012106251A2 (en) * | 2011-01-31 | 2012-08-09 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Pertussis vaccine |
PL404247A1 (pl) * | 2013-06-07 | 2014-12-08 | Wrocławskie Centrum Badań Eit + Spółka Z Ograniczoną Odpowiedzialnością | Koniugat oligocukru LOS Bordetella pertussis i toksyny krztuśca i jego zastosowanie w profilaktyce i leczeniu zakażeń wywoływanych przez Bordetella pertussis |
EP3242883A4 (en) * | 2015-01-06 | 2018-10-17 | ImmunoVaccine Technologies Inc. | Lipid a mimics, methods of preparation, and uses thereof |
WO2016168815A1 (en) * | 2015-04-16 | 2016-10-20 | Iventprise LLC | Bordetella pertussis immunogenic vaccine compositions |
-
2018
- 2018-12-28 CU CU2018000159A patent/CU20180159A7/es unknown
-
2019
- 2019-04-08 CN CN201980000706.9A patent/CN111819184B/zh active Active
- 2019-04-08 WO PCT/CU2019/050001 patent/WO2020135898A1/es active Application Filing
Also Published As
Publication number | Publication date |
---|---|
CN111819184A (zh) | 2020-10-23 |
CN111819184B (zh) | 2024-01-12 |
WO2020135898A1 (es) | 2020-07-02 |
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