AU2001257917A1 - Alpha lipoic acid based food supplement to increase lean muscle mass and strength - Google Patents
Alpha lipoic acid based food supplement to increase lean muscle mass and strengthInfo
- Publication number
- AU2001257917A1 AU2001257917A1 AU2001257917A AU5791701A AU2001257917A1 AU 2001257917 A1 AU2001257917 A1 AU 2001257917A1 AU 2001257917 A AU2001257917 A AU 2001257917A AU 5791701 A AU5791701 A AU 5791701A AU 2001257917 A1 AU2001257917 A1 AU 2001257917A1
- Authority
- AU
- Australia
- Prior art keywords
- food supplement
- glutamine
- lipoic acid
- derivative
- per
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/316—Foods, ingredients or supplements having a functional effect on health having an effect on regeneration or building of ligaments or muscles
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pediatric Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Meat, Egg Or Seafood Products (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17895700P | 2000-02-01 | 2000-02-01 | |
| US60/178957 | 2000-02-01 | ||
| PCT/IB2001/000743 WO2001056402A2 (en) | 2000-02-01 | 2001-02-01 | Alpha lipoic acid based food supplement to increase lean muscle mass and strength |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2001257917A1 true AU2001257917A1 (en) | 2001-08-14 |
Family
ID=22654611
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001257917A Abandoned AU2001257917A1 (en) | 2000-02-01 | 2001-02-01 | Alpha lipoic acid based food supplement to increase lean muscle mass and strength |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US20020006907A1 (ja) |
| EP (1) | EP1255454A2 (ja) |
| JP (1) | JP2003521256A (ja) |
| KR (1) | KR20020090214A (ja) |
| AU (1) | AU2001257917A1 (ja) |
| CA (1) | CA2399500A1 (ja) |
| CZ (1) | CZ20022927A3 (ja) |
| MX (1) | MXPA02007466A (ja) |
| RU (1) | RU2002122099A (ja) |
| WO (1) | WO2001056402A2 (ja) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6905707B2 (en) * | 1998-05-28 | 2005-06-14 | Medical Research Institute | Controlled release arginine alpha ketoglutarate |
| US20060024367A1 (en) * | 1998-05-28 | 2006-02-02 | Byrd Edward A | Controlled release alpha lipoic acid formulation with an inositol compound |
| US20060128806A1 (en) * | 1998-05-28 | 2006-06-15 | Medical Research Institute | Controlled release arginine alpha-ketoglutarate |
| US20050085498A1 (en) * | 1998-05-28 | 2005-04-21 | Byrd Edward A. | Oral formulation of lipid soluble thiamine, lipoic acid, creatine derivative, and L-arginine alpha-ketoglutarate |
| US6197340B1 (en) * | 1998-05-28 | 2001-03-06 | Medical Research Institute | Controlled release lipoic acid |
| MXPA02003861A (es) * | 1999-10-18 | 2003-07-14 | Muscletech Res And Dev Inc | Suplemento alimenticio para incrementar la masa sin desarrollar y la fuerza. |
| US20020076470A1 (en) | 2000-10-31 | 2002-06-20 | Colgate-Palmolive Company | Composition and method |
| US8669282B2 (en) * | 2000-10-31 | 2014-03-11 | Hill's Pet Nutrition, Inc. | Companion animal compositions including lipoic acid and methods of use thereof |
| US20030212134A1 (en) * | 2001-04-16 | 2003-11-13 | Dykstra John C. | Combination of pinitol and creatine to enhance uptake and retention of creatine |
| DE10151764A1 (de) * | 2001-10-19 | 2003-05-08 | Basf Ag | Kombination von Liponsäure und Glutamin in Lebens- und Arzneimitteln |
| AU2003234146A1 (en) * | 2002-04-22 | 2003-11-03 | Experimental And Applied Sciences, Inc. | Food supplements containing 4-hydroxyisoleucine and creatine |
| US7220442B2 (en) | 2003-02-20 | 2007-05-22 | Slim-Fast Foods Company, Division Of Conopco, Inc. | Nutrition bar and process of making components |
| JP2005027524A (ja) * | 2003-07-08 | 2005-02-03 | Ajinomoto Co Inc | 経口アミノ酸組成物 |
| JP4849792B2 (ja) * | 2004-09-14 | 2012-01-11 | オリザ油化株式会社 | 美容用組成物 |
| US20080095865A1 (en) * | 2004-09-29 | 2008-04-24 | Aplodan Formulations Ltd. | Composition and method for increasing lean muscle mass, decreasing muscle loss, increasing muscle strength and improving athletic performance |
| WO2006034586A1 (en) * | 2004-09-29 | 2006-04-06 | Aplodan Formulations Ltd. | Nutritional composition for promoting muscle performance and acting as hydrogen (h+) blocker |
| RU2432159C2 (ru) * | 2004-11-24 | 2011-10-27 | Хилл'С Пет Ньютришн, Инк. | Способы для улучшения обезвреживания печенью ксенобиотических веществ у животных |
| US20090176864A1 (en) * | 2004-11-24 | 2009-07-09 | Hill's Pet Nutrition, Inc. | Methods For Improving Hepatic and Immune Function In An Animal |
| WO2006071919A2 (en) | 2004-12-29 | 2006-07-06 | Hill's Pet Nutrition, Inc. | Methods for inhibiting a decline in learning and/or memory in animals |
| US8252742B2 (en) | 2004-12-30 | 2012-08-28 | Hill's Pet Nutrition, Inc. | Methods for enhancing the quality of life of a senior animal |
| AU2005322887B2 (en) * | 2004-12-30 | 2010-03-11 | Hill's Pet Nutrition, Inc. | Methods for enhancing the quality of life of a senior animal |
| WO2006123436A1 (ja) * | 2005-05-19 | 2006-11-23 | Nippon Meat Packers, Inc. | 運動機能向上性食品 |
| CN101262780B (zh) * | 2005-07-14 | 2013-04-24 | 希尔氏宠物营养品公司 | 一种延长动物生命的方法 |
| EP1754478B1 (en) * | 2005-08-04 | 2008-12-31 | Extarma AG | Liquid Composition comprising arginine and alpha-lipoic acid and its use for improvement of sexual function |
| CN100493514C (zh) * | 2005-08-05 | 2009-06-03 | 杨喜鸿 | 磷酸肌酸钠和镁盐的组合药物 |
| WO2007028211A1 (en) * | 2005-09-09 | 2007-03-15 | Murray Goulburn Co-Operative Co Limited | Composition of whey growth factor extract for reducing muscle inflammation |
| CN101282763B (zh) * | 2005-09-09 | 2012-09-26 | 墨累古尔本合作有限公司 | 来源于乳的组合物及其用于增强肌肉量或肌肉力量的用途 |
| WO2007053943A1 (en) * | 2005-11-08 | 2007-05-18 | Multi Formulations Ltd. | The use of compositions comprising ketoacids and amino acids for increasing muscle mass and muscle performance |
| US20070117867A1 (en) * | 2005-11-08 | 2007-05-24 | Gardiner Paul T | Kit comprising three independent compositions and methods for building muscle, increasing strength, increasing muscle size, increasing muscle performance and reducing muscle fatigue |
| DK1957061T3 (da) * | 2005-11-30 | 2011-07-25 | Novartis Pharma Gmbh | Kombination omfattende mindst én aminosyre og en PKR-inhibitor til anvendelse i behandlingen af muskelsvind |
| WO2007095117A2 (en) * | 2006-02-10 | 2007-08-23 | Multi Formulations Ltd. | Method for improving the oral administration of alpha-lipoic acid |
| US9119416B2 (en) * | 2006-03-23 | 2015-09-01 | Kyowa Hakko Bio Co., Ltd. | Muscle fatigue remedy |
| US8110231B2 (en) * | 2006-04-10 | 2012-02-07 | Kraft Foods Global Brands Llc | Methods for making improved texture cereal bars |
| US20080058254A1 (en) * | 2006-08-31 | 2008-03-06 | Heuer Marvin A | Composition and method for enhancing or promoting the activity of insulin, enhancing skeletal muscle growth, reducing skeletal muscle loss, and increasing the energy supply to skeletal muscle |
| US7314945B1 (en) * | 2007-02-20 | 2008-01-01 | Multi Formulations Ltd. | Creatine-fatty acids |
| US7511162B2 (en) * | 2007-02-20 | 2009-03-31 | Multi Formulations Ltd. | Preparation of amino acid-fatty acid anhydrides |
| US7319157B1 (en) * | 2007-02-20 | 2008-01-15 | Multi Formulations Ltd. | Creatine-fatty acids |
| WO2008138090A1 (en) * | 2007-05-10 | 2008-11-20 | Multi Formulations Ltd. | Preparation of amino acid-fatty acid anhydrides |
| US20090163573A1 (en) * | 2007-12-21 | 2009-06-25 | Multi Formulations Ltd. | Compositions and methods for enhancing protein accretion in skeletal muscle |
| WO2009079740A1 (en) * | 2007-12-21 | 2009-07-02 | Multi Formulations Ltd. | Compositions and methods for enhancing hypertrophy in skeletal muscle |
| AU2016200420B2 (en) * | 2008-12-30 | 2017-03-02 | Hill's Pet Nutrition, Inc. | Companion animal compositions including lipoic acid and methods of use thereof |
| AU2009335094B2 (en) | 2008-12-30 | 2012-11-15 | Hill's Pet Nutrition, Inc. | Use of lipoic acid for treating or preventing degenerative joint conditions, osteoarthritis, cartilage damage, and related disorders in companion animals |
| CN102271530A (zh) * | 2008-12-30 | 2011-12-07 | 希尔氏宠物营养品公司 | 用于治疗和预防伴侣动物的与体重相关疾病的组合物和方法 |
| ES2441365T3 (es) * | 2009-11-29 | 2014-02-04 | Nestec S.A. | Protocolos de dosificación para incrementar la síntesis de proteínas en un individuo activo |
| CN106937742A (zh) * | 2010-01-29 | 2017-07-11 | 雅培制药有限公司 | 包含喷雾干燥的hmb的营养粉 |
| ES2481865T3 (es) | 2010-01-29 | 2014-07-31 | Abbott Laboratories | Emulsiones nutricionales que comprenden HMB de calcio |
| US9693577B2 (en) | 2010-01-29 | 2017-07-04 | Abbott Laboratories | Method of preparing a nutritional powder comprising spray dried HMB |
| TWI526161B (zh) | 2010-06-10 | 2016-03-21 | 亞培公司 | 包含鈣ｈｍｂ及可溶性蛋白質之實質上透明營養液 |
| JP2012062309A (ja) * | 2010-08-19 | 2012-03-29 | Nisshin Pharma Inc | 筋肉増加用組成物 |
| EP2875736B1 (en) | 2013-11-26 | 2016-07-27 | Citrage | N-Carbamoylputrescine to enhance muscle protein synthesis |
| US10987340B2 (en) | 2015-07-24 | 2021-04-27 | Jesse Alexander Galinski | Composition and method for rapidly inducing an endogenous ketosis |
| JOP20190147A1 (ar) * | 2016-12-19 | 2019-06-18 | Axcella Health Inc | تركيبات حمض أميني وطرق لمعالجة أمراض واضطرابات العضلات |
| JOP20190146A1 (ar) | 2016-12-19 | 2019-06-18 | Axcella Health Inc | تركيبات حمض أميني وطرق لمعالجة أمراض الكبد |
| EP3668499A1 (en) | 2017-08-14 | 2020-06-24 | Axcella Health Inc. | Amino acid compositions for the treatment of liver disease |
| EP3810123A1 (en) | 2018-06-20 | 2021-04-28 | Axcella Health Inc. | Compositions and methods for the treatment of fat infiltration in muscle |
| WO2019246299A1 (en) * | 2018-06-20 | 2019-12-26 | Axcella Health Inc. | Compositions and methods for the reduction or treatment of insulin resistance and metabolic conditions |
| US20240138458A1 (en) * | 2020-08-14 | 2024-05-02 | Seoul National University Hospital | Protein food composition having ultra-low calories and high bioabsorption rate and method for providing diet information using same |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA716628B (en) * | 1970-10-15 | 1972-06-28 | Richardson Merrell Spa | Composition and method for treatment of hepatic disease and mental fatigue |
| US4070488A (en) * | 1975-11-25 | 1978-01-24 | Davis Rachel D | Nutritive composition |
| US4687782A (en) * | 1984-12-10 | 1987-08-18 | Nutri-Fuels Systems, Inc. | Nutritional composition for enhancing skeletal muscle adaptation to exercise training |
| IL80783A0 (en) * | 1986-10-17 | 1987-02-27 | Univ Bar Ilan | Food supplements |
| US4766004A (en) * | 1986-12-19 | 1988-08-23 | Warner-Lambert Company | Crunchy, highly palatable, bulk-increasing, dietary fiber supplement composition |
| US5026721A (en) * | 1989-06-05 | 1991-06-25 | Dudrick Stanley J | Amino acid nutritional supplement and regimen for enhancing physical performance through sound nutrition |
| US5051258A (en) * | 1989-10-13 | 1991-09-24 | Natrol, Inc. | Dietary supplement for children |
| US5164384A (en) * | 1991-06-19 | 1992-11-17 | Metagenics, Inc. | Anabolic mineral formula |
| US5292538A (en) * | 1992-07-22 | 1994-03-08 | Metagenics, Inc. | Improved sustained energy and anabolic composition and method of making |
| US5292722A (en) * | 1992-11-06 | 1994-03-08 | Brigham And Women's Hospital | Intravenous solution that diminishes body protein loss |
| US5726146A (en) * | 1994-12-06 | 1998-03-10 | Natural Supplement Association, Incorporated | Non-steroidal, anabolic dietary supplement and method to increase lean mass without linked increase fat mass |
| US6008252A (en) * | 1996-07-26 | 1999-12-28 | Beale; Paxton K. | Method for increasing muscle mass in a mammal |
| US5976568A (en) * | 1997-02-21 | 1999-11-02 | Medical Doctors' Research Institute, Inc. | Modular system of dietary supplement compositions for optimizing health benefits and methods |
| US5925378A (en) * | 1997-03-31 | 1999-07-20 | Fortress Systems, L.L.C. | Method for enhancing delivery and uniformity of concentration of cellular creatine |
| US5888553A (en) * | 1997-04-08 | 1999-03-30 | Infinity, Inc. | Non-steroidal anabolic composition |
| US6193973B1 (en) * | 1997-08-22 | 2001-02-27 | B. David Tuttle | Dietary supplement for boosting energy and increasing muscular strength |
| US5972985A (en) * | 1997-11-03 | 1999-10-26 | Cytos Pharmaceuticals, Llc | Histidine containing nutriceutical compositions |
| US6262019B1 (en) * | 1998-04-30 | 2001-07-17 | Vit-Immune, L. C. | Method of treatment of glutathione deficient mammals |
| CA2246014C (en) * | 1998-08-21 | 2001-12-11 | Paul T. Gardiner | Food supplements and methods comprising lipoic acid and creatine |
| US6136339A (en) * | 1998-08-21 | 2000-10-24 | Gardiner; Paul T. | Food supplements and methods comprising lipoic acid and creatine |
| WO2000072854A1 (en) * | 1999-06-02 | 2000-12-07 | Ashni Naturaceuticals, Inc. | A dietary supplement containing vanadyl sulfate, alpha-lipoic acid, and taurine |
| MXPA02003861A (es) * | 1999-10-18 | 2003-07-14 | Muscletech Res And Dev Inc | Suplemento alimenticio para incrementar la masa sin desarrollar y la fuerza. |
| EP1112693B1 (en) * | 1999-12-30 | 2006-03-22 | Kerry Group Services Ltd | Composition comprising carbohydrate and peptide material and its use as an energy supplement after or during physical exercise or as a metabolic nutrient for oral consumption |
| US6277842B1 (en) * | 2000-10-17 | 2001-08-21 | James Alexander Carthron | Dietary supplemental method for fat and weight reduction |
-
2001
- 2001-02-01 CZ CZ20022927A patent/CZ20022927A3/cs unknown
- 2001-02-01 US US09/775,431 patent/US20020006907A1/en not_active Abandoned
- 2001-02-01 MX MXPA02007466A patent/MXPA02007466A/es unknown
- 2001-02-01 AU AU2001257917A patent/AU2001257917A1/en not_active Abandoned
- 2001-02-01 WO PCT/IB2001/000743 patent/WO2001056402A2/en not_active Application Discontinuation
- 2001-02-01 KR KR1020027009878A patent/KR20020090214A/ko not_active Application Discontinuation
- 2001-02-01 RU RU2002122099/13A patent/RU2002122099A/ru not_active Application Discontinuation
- 2001-02-01 EP EP01948923A patent/EP1255454A2/en not_active Withdrawn
- 2001-02-01 CA CA002399500A patent/CA2399500A1/en not_active Abandoned
- 2001-02-01 JP JP2001556108A patent/JP2003521256A/ja active Pending
-
2003
- 2003-04-15 US US10/414,359 patent/US20040023889A1/en not_active Abandoned
-
2004
- 2004-05-07 US US10/841,404 patent/US20040208942A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1255454A2 (en) | 2002-11-13 |
| RU2002122099A (ru) | 2004-08-10 |
| US20020006907A1 (en) | 2002-01-17 |
| MXPA02007466A (es) | 2004-02-26 |
| CA2399500A1 (en) | 2001-08-09 |
| US20040208942A1 (en) | 2004-10-21 |
| CZ20022927A3 (cs) | 2003-06-18 |
| WO2001056402A2 (en) | 2001-08-09 |
| JP2003521256A (ja) | 2003-07-15 |
| US20040023889A1 (en) | 2004-02-05 |
| WO2001056402A3 (en) | 2002-08-22 |
| KR20020090214A (ko) | 2002-11-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK4 | Application lapsed section 142(2)(d) - no continuation fee paid for the application |