AU2001250850A1 - Beta-amino acid derivatives as inhibitors of matrix metalloproteases and tnf-alpha - Google Patents

Beta-amino acid derivatives as inhibitors of matrix metalloproteases and tnf-alpha

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Publication number
AU2001250850A1
AU2001250850A1 AU2001250850A AU5085001A AU2001250850A1 AU 2001250850 A1 AU2001250850 A1 AU 2001250850A1 AU 2001250850 A AU2001250850 A AU 2001250850A AU 5085001 A AU5085001 A AU 5085001A AU 2001250850 A1 AU2001250850 A1 AU 2001250850A1
Authority
AU
Australia
Prior art keywords
methyl
quinolinyl
hydroxyamino
methoxy
oxoethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001250850A
Other languages
English (en)
Inventor
Carl Decicco
Jingwu Duan
Bryan W. King
Thomas P. MADUSKUIE JR.
Matthew E. Voss
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Pharma Co
Original Assignee
DuPont Merck Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DuPont Merck Pharmaceutical Co filed Critical DuPont Merck Pharmaceutical Co
Publication of AU2001250850A1 publication Critical patent/AU2001250850A1/en
Abandoned legal-status Critical Current

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    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/34Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
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AU2001250850A 2000-03-17 2001-03-15 Beta-amino acid derivatives as inhibitors of matrix metalloproteases and tnf-alpha Abandoned AU2001250850A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US19018300P 2000-03-17 2000-03-17
US60190183 2000-03-17
US23546700P 2000-09-26 2000-09-26
US60235467 2000-09-26
US25206200P 2000-11-20 2000-11-20
US60252062 2000-11-20
PCT/US2001/008336 WO2001070734A2 (en) 2000-03-17 2001-03-15 Beta-amino acid derivatives as inhibitors of matrix metalloproteases and tnf-alpha

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AU2001250850A1 true AU2001250850A1 (en) 2001-10-03

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ATE260272T1 (de) 2004-03-15
CA2400168A1 (en) 2001-09-27
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ES2215893T3 (es) 2004-10-16
BR0109469A (pt) 2003-04-29
HK1049334A1 (en) 2003-05-09
WO2001070734A2 (en) 2001-09-27
US6495565B2 (en) 2002-12-17
HK1049334B (zh) 2004-07-16
DE60102137D1 (de) 2004-04-01
JP2003528097A (ja) 2003-09-24
EP1263756B1 (en) 2004-02-25
CN1420881A (zh) 2003-05-28
US20020013341A1 (en) 2002-01-31
NZ521245A (en) 2004-04-30

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