AU2001248352A1 - Diagnosis of diseases associated with the cell cycle - Google Patents

Diagnosis of diseases associated with the cell cycle

Info

Publication number
AU2001248352A1
AU2001248352A1 AU2001248352A AU4835201A AU2001248352A1 AU 2001248352 A1 AU2001248352 A1 AU 2001248352A1 AU 2001248352 A AU2001248352 A AU 2001248352A AU 4835201 A AU4835201 A AU 4835201A AU 2001248352 A1 AU2001248352 A1 AU 2001248352A1
Authority
AU
Australia
Prior art keywords
dna
recited
sequences
genes
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001248352A
Other languages
English (en)
Inventor
Kurt Berlin
Alexander Olek
Christian Piepenbrock
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Epigenomics AG
Original Assignee
Epigenomics AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10013847A external-priority patent/DE10013847A1/de
Priority claimed from DE10019058A external-priority patent/DE10019058A1/de
Priority claimed from DE10032529A external-priority patent/DE10032529A1/de
Application filed by Epigenomics AG filed Critical Epigenomics AG
Publication of AU2001248352A1 publication Critical patent/AU2001248352A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Hospice & Palliative Care (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU2001248352A 2000-03-15 2001-03-15 Diagnosis of diseases associated with the cell cycle Abandoned AU2001248352A1 (en)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
DE10013847.0 2000-03-15
DE10013847A DE10013847A1 (de) 2000-03-15 2000-03-15 Oligonukleotide oder PNA-Oligomere und Verfahren zur parallelen Detektion des Methylierungszustandes genomischer DNA
DE10019058A DE10019058A1 (de) 2000-04-06 2000-04-06 Detektion von Variationen des DNA-Methylierungsprofils
DE10019058.8 2000-04-06
DE10019173 2000-04-07
DE10019173.8 2000-04-07
DE10032529.7 2000-06-30
DE10032529A DE10032529A1 (de) 2000-06-30 2000-06-30 Diagnose von bedeutenden genetischen Parametern innerhalb des Major Histocompatibility Complex (MHC)
DE10043826 2000-09-01
DE10043826.1 2000-09-01
PCT/EP2001/002945 WO2001068911A2 (en) 2000-03-15 2001-03-15 Diagnosis of diseases associated with the cell cycle

Publications (1)

Publication Number Publication Date
AU2001248352A1 true AU2001248352A1 (en) 2001-09-24

Family

ID=27512367

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2001248352A Abandoned AU2001248352A1 (en) 2000-03-15 2001-03-15 Diagnosis of diseases associated with the cell cycle
AU2001250381A Abandoned AU2001250381A1 (en) 2000-03-15 2001-03-15 Diagnosis of diseases associated with tumor suppressor genes and oncogenes

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2001250381A Abandoned AU2001250381A1 (en) 2000-03-15 2001-03-15 Diagnosis of diseases associated with tumor suppressor genes and oncogenes

Country Status (5)

Country Link
US (2) US20040029123A1 (ja)
EP (2) EP1268855A2 (ja)
JP (2) JP2004507213A (ja)
AU (2) AU2001248352A1 (ja)
WO (2) WO2001068911A2 (ja)

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DE69837996T2 (de) 1997-01-14 2008-02-28 Human Genome Sciences, Inc. Tumornekrosefaktor-rezeptoren 6 alpha& 6 beta
US7285267B2 (en) 1997-01-14 2007-10-23 Human Genome Sciences, Inc. Tumor necrosis factor receptors 6α & 6β
US6818404B2 (en) * 1997-10-23 2004-11-16 Exact Sciences Corporation Methods for detecting hypermethylated nucleic acid in heterogeneous biological samples
AU2001278420A1 (en) 2000-04-06 2001-11-07 Epigenomics Ag Diagnosis of diseases associated with dna repair
JP2004501666A (ja) * 2000-06-30 2004-01-22 エピゲノミクス　アーゲー 薬理ゲノミクスのメチル化状態分析のための方法及び核酸
WO2002018632A2 (de) 2000-09-01 2002-03-07 Epigenomics Ag Verfahren zur bestimmung des methylierungsgrades von bestimmten cytosinen in genomischer dna im sequenzkontext 5'-cpg-3'
DE10054974A1 (de) * 2000-11-06 2002-06-06 Epigenomics Ag Diagnose von mit Cdk4 assoziierten Krankheiten
EP1346043A2 (en) * 2000-11-20 2003-09-24 Diadexus, Inc. Compositions and methods relating to lung specific genes and proteins
EP1410304A2 (en) * 2001-03-26 2004-04-21 Epigenomics AG Method for epigenetic feature selection
DE10128508A1 (de) * 2001-06-14 2003-02-06 Epigenomics Ag Verfahren und Nukleinsäuren für die Differenzierung von Prostata-Tumoren
WO2003031932A2 (en) 2001-10-05 2003-04-17 Case Western Reserve University Methods and compositions for detecting colon cancers
ATE495184T1 (de) 2001-11-07 2011-01-15 Syngenta Participations Ag Promotoren zur regulierung der genexpression in pflanzenwurzeln
US20030215842A1 (en) * 2002-01-30 2003-11-20 Epigenomics Ag Method for the analysis of cytosine methylation patterns
EP1340818A1 (en) * 2002-02-27 2003-09-03 Epigenomics AG Method and nucleic acids for the analysis of a colon cell proliferative disorder
WO2003085125A1 (en) * 2002-04-03 2003-10-16 Agy Therapeutics, Inc. Use of biomolecular targets in the treatment and visualization of brain tumors
WO2004013311A2 (en) * 2002-08-06 2004-02-12 Diadexus, Inc. Compositions and methods relating to ovarian specific genes and proteins
US20040029128A1 (en) * 2002-08-08 2004-02-12 Epigenomics, Inc. Methods and nucleic acids for the analysis of CpG dinucleotide methylation status associated with the calcitonin gene
WO2004035803A2 (en) * 2002-10-01 2004-04-29 Epigenomics Ag Method and nucleic acids for the treatment of breast cell proliferative disorders
CA2442438C (en) * 2002-10-04 2012-06-19 Nisshinbo Industries, Inc. Oligonucleotide-immobilized substrate for detecting methylation
WO2004070020A2 (en) * 2003-01-31 2004-08-19 Monsanto Technology Llc Glyphosate tolerant alfalfa events and methods for detection thereof
EP1693468A1 (en) 2005-02-16 2006-08-23 Epigenomics AG Method for determining the methylation pattern of a polynucleic acid
SI1871912T1 (sl) 2005-04-15 2012-06-29 Epigenomics Ag Postopek za določitev DNA metilacije v vzorcih krvi ali urina
JP2008538700A (ja) * 2005-04-22 2008-11-06 モルフォテック、インク． 免疫エフェクター活性を有するエンドシアリン細胞に内部移行する抗体
WO2007032748A1 (en) * 2005-09-15 2007-03-22 Agency For Science, Technology & Research Method for detecting dna methylation
US20070161006A1 (en) * 2006-01-10 2007-07-12 Vita Genomics, Inc. Single nucleotide polymorphisms in protein-tyrosine phosphatase receptor-type delta for the diagnosis of susceptibility to infection and asthma
US8084734B2 (en) * 2006-05-26 2011-12-27 The George Washington University Laser desorption ionization and peptide sequencing on laser induced silicon microcolumn arrays
ES2546182T3 (es) * 2006-07-21 2015-09-21 Epigenomics Ag Métodos y kits para análisis de metilación en trastornos proliferativos celulares colorrectales
KR101529334B1 (ko) 2007-04-05 2015-06-16 모르포테크, 인크. 엔도시알린의 리간드에 대한 결합을 억제하는 방법
WO2009021019A1 (en) * 2007-08-06 2009-02-12 Health Research Inc. Methods for analysis of pdef and survivin as interconnected cancer biomarkers and targets for personalized medicine
EP2058403A1 (en) * 2007-11-09 2009-05-13 Rheinische Friedrich-Wilhelms-Universität Bonn DUSP4 as clinically relevant epigenetic marker and therapeutic target in gliomas and other tumors
AU2008338526A1 (en) * 2007-12-14 2009-06-25 Immune Disease Institute, Inc. Treatment and prevention of HIV infection
US20110053149A1 (en) * 2007-12-28 2011-03-03 Judith Mary Boer Methylation detection in the genomic region of a receptor proteintyrosine phosphatase gamma gene for detection and/or diagnosis of a tumour
US8110796B2 (en) 2009-01-17 2012-02-07 The George Washington University Nanophotonic production, modulation and switching of ions by silicon microcolumn arrays
US9490113B2 (en) * 2009-04-07 2016-11-08 The George Washington University Tailored nanopost arrays (NAPA) for laser desorption ionization in mass spectrometry
WO2011090741A2 (en) * 2009-12-29 2011-07-28 Opko Curna, Llc TREATMENT OF TUMOR PROTEIN 63 (p63) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO p63
WO2012018982A2 (en) * 2010-08-05 2012-02-09 Tufts Medical Center, Inc. Methods and kits for modulating tumor invasiveness and metastatic potential
WO2012149014A1 (en) 2011-04-25 2012-11-01 OSI Pharmaceuticals, LLC Use of emt gene signatures in cancer drug discovery, diagnostics, and treatment
US9732390B2 (en) 2012-09-20 2017-08-15 The Chinese University Of Hong Kong Non-invasive determination of methylome of fetus or tumor from plasma
US10706957B2 (en) 2012-09-20 2020-07-07 The Chinese University Of Hong Kong Non-invasive determination of methylome of tumor from plasma
CN105637126B (zh) 2013-08-22 2022-09-23 雅普顿生物系统公司 使用电方法的分子分析物的数字分析
CN108186665B (zh) * 2018-01-02 2020-03-20 深圳市第二人民医院 干扰长链非编码rna pvt1表达的试剂及其应用
CN108977457B (zh) * 2018-08-31 2021-04-02 长江大学 一种黄鳝抗菌肽的制备方法
CN113528657B (zh) * 2020-06-18 2022-09-30 广州达健生物科技有限公司 用于检测食管癌的组合物及其试剂盒和应用

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US6605432B1 (en) * 1999-02-05 2003-08-12 Curators Of The University Of Missouri High-throughput methods for detecting DNA methylation
DE10128508A1 (de) * 2001-06-14 2003-02-06 Epigenomics Ag Verfahren und Nukleinsäuren für die Differenzierung von Prostata-Tumoren
WO2003004696A2 (en) * 2001-07-02 2003-01-16 Epigenomics Ag A distributed system for epigenetic based prediction of complex phenotypes

Also Published As

Publication number Publication date
EP1283905A2 (en) 2003-02-19
JP2004507213A (ja) 2004-03-11
US20040048254A1 (en) 2004-03-11
AU2001250381A1 (en) 2001-09-24
WO2001068911A2 (en) 2001-09-20
WO2001068911A8 (en) 2002-10-24
US20040029123A1 (en) 2004-02-12
WO2001068912A3 (en) 2002-04-18
WO2001068911A3 (en) 2002-11-28
WO2001068912A2 (en) 2001-09-20
JP2004507214A (ja) 2004-03-11
EP1268855A2 (en) 2003-01-02

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Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted