AU1554592A - Interleukin 6 composition and production thereof - Google Patents

Interleukin 6 composition and production thereof

Info

Publication number
AU1554592A
AU1554592A AU15545/92A AU1554592A AU1554592A AU 1554592 A AU1554592 A AU 1554592A AU 15545/92 A AU15545/92 A AU 15545/92A AU 1554592 A AU1554592 A AU 1554592A AU 1554592 A AU1554592 A AU 1554592A
Authority
AU
Australia
Prior art keywords
human interleukin
interleukin
composition
production
composition containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU15545/92A
Other languages
English (en)
Inventor
Keizo Hanada
Kazuo Hosoi
Shigeru Ichikura
Makoto Kihara
Masanobu Naruto
Shingou Sakurai
Emiko Sano
Jun Utsumi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toray Industries Inc
Original Assignee
Toray Industries Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries Inc filed Critical Toray Industries Inc
Publication of AU1554592A publication Critical patent/AU1554592A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/204—IL-6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5412—IL-6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0656—Adult fibroblasts

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
AU15545/92A 1991-04-18 1992-04-17 Interleukin 6 composition and production thereof Abandoned AU1554592A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP3-86602 1991-04-18
JP8660291 1991-04-18
JP8828491 1991-04-19
JP3-88284 1991-04-19

Publications (1)

Publication Number Publication Date
AU1554592A true AU1554592A (en) 1992-11-17

Family

ID=26427716

Family Applications (1)

Application Number Title Priority Date Filing Date
AU15545/92A Abandoned AU1554592A (en) 1991-04-18 1992-04-17 Interleukin 6 composition and production thereof

Country Status (10)

Country Link
EP (1) EP0550756B1 (enExample)
KR (1) KR930700550A (enExample)
AT (1) ATE210150T1 (enExample)
AU (1) AU1554592A (enExample)
CA (1) CA2085744A1 (enExample)
DE (1) DE69232259T2 (enExample)
ES (1) ES2164050T3 (enExample)
FI (1) FI925745A7 (enExample)
TW (1) TW221379B (enExample)
WO (1) WO1992018537A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5338834A (en) * 1993-01-26 1994-08-16 Allelix Biopharmaceuticals Inc. Ultrapure human interleukin-6
JP3394240B2 (ja) 1997-12-03 2003-04-07 ロシュ ダイアグノスティックス ゲーエムベーハー 適当にグリコシル化されたポリペプチドの製造方法
US6998267B1 (en) 1998-12-09 2006-02-14 The Dow Chemical Company Method for manufacturing glycoproteins having human-type glycosylation
EP2251426A1 (en) 1999-10-26 2010-11-17 Stichting Dienst Landbouwkundig Onderzoek Mammalian-type glycosylation in plants
WO2002057468A2 (en) 2001-01-19 2002-07-25 The Dow Chemical Company Method for secretory production of glycoprotein having human-type sugar chain using plant cell
CA2799805C (en) 2002-03-19 2016-05-17 Stichting Dienst Landbouwkundig Onderzoek Optimizing glycan processing in plants
NZ534881A (en) 2002-03-19 2006-09-29 Plant Res Internat B Mammalian GnTIII expression in plants
CL2003002461A1 (es) 2002-11-27 2005-01-07 Dow Chemical Company Agroscien Inmunoglobulina que comprende al menos un glicano afucosilado, composicion que la contiene, secuencia nucleotidica y vector que la comprende, procedimiento para producir dicha inmunoglobulina en plantas.
AU2008237632B2 (en) 2007-04-17 2014-01-16 Stichting Dienst Landbouwkundig Onderzoek Mammalian-type glycosylation in plants by expression of non-mammalian glycosyltransferases

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6062997A (ja) * 1983-09-17 1985-04-11 Mochida Pharmaceut Co Ltd インタ−フエロンの生産方法
DE3519011A1 (de) * 1985-05-25 1986-11-27 Behringwerke Ag, 3550 Marburg Verfahren zur herstellung eines materials zur affinitaetschromatographie
JPS62153755A (ja) * 1985-12-27 1987-07-08 Showa Denko Kk クロマトグラフイ−用吸着担体
JP2648860B2 (ja) * 1986-05-08 1997-09-03 イエダ リサーチ アンド デベロップメント コンパニー リミテッド ヒトインターフエロン−β２Ａ及びヒトインターフエロン−β２Ｂ、該インターフエロンをコードする遺伝子を含むベクター、該インターフエロンを産生するセルライン及び該インターフエロンの医薬品としての用途
IE67035B1 (en) * 1986-07-08 1996-02-21 Genetics Inst Production and use of non-glycosylated IL-6
JP2676336B2 (ja) * 1986-08-06 1997-11-12 忠三 岸本 ヒトｂ細胞分化因子の遺伝子
JPS63150297A (ja) * 1986-12-12 1988-06-22 Ajinomoto Co Inc 新規ｂ細胞分化因子蛋白標品
EP0315782B1 (de) * 1987-10-13 1994-09-28 Dr. Karl Thomae GmbH Verfahren zur Herstellung von Proteinen
JPH03133935A (ja) * 1989-10-19 1991-06-07 Toray Ind Inc ヒト天然型インターロイキン６組成物

Also Published As

Publication number Publication date
ATE210150T1 (de) 2001-12-15
KR930700550A (ko) 1993-03-15
DE69232259T2 (de) 2002-06-13
FI925745L (fi) 1992-12-17
EP0550756B1 (en) 2001-12-05
DE69232259D1 (de) 2002-01-17
CA2085744A1 (en) 1992-10-19
EP0550756A1 (en) 1993-07-14
ES2164050T3 (es) 2002-02-16
FI925745A0 (fi) 1992-12-17
FI925745A7 (fi) 1992-12-17
EP0550756A4 (enExample) 1994-04-27
WO1992018537A1 (en) 1992-10-29
TW221379B (enExample) 1994-03-01

Similar Documents

Publication Publication Date Title
AU2294788A (en) Apparatus for the intensive, controlled production of microorganisms by photosynthesis
HUT67653A (en) Nor-bile-acid derivatives, process for producing them and pharmaceutical compositions containing them
NO302884B1 (no) Krystallinske 3,4,4-trisubstituert-piperidinyl-N-alkylkarboksylater og mellomprodukter, fremgangsmåte for fremstilling av de krystallinske karboksylatene, farmasöytiske preparater inneholdende disse og deres anvendelse
HUT49592A (en) Process for producing bis/hydroxymethyl/-cyclobutyl-purines and pyrimidines, as well as pharmaceutical compositions comprising same
AU2993892A (en) Novel azaheterocyclylmethyl-chromans
CS38989A2 (en) Method of phenoxyacetamidoderivative production
IE882335L (en) Pyridinium derivatives, their production and use
HU9200204D0 (en) Process for the production of benzyloxi-phenyl derivatives and medical preparations containing them
AU1554592A (en) Interleukin 6 composition and production thereof
ATE50776T1 (de) Anthracyclin-derivate, ein mikrobiologisches verfahren zu ihrer herstellung und ihre verwendung als cytostatika.
EP0146239A3 (en) Bioconversion production of ascorbic acid
ES2026059A6 (es) Procedimiento mejorado para la sintesis de 1-((1-(2-(trifluoreometil)-4-pirimidinil)-4-piperidinil)metil)-2-pirrolidinona.
IE821049L (en) Aminocyclitol derivatives
ATE118004T1 (de) 4-amidino-chroman und 4-amidino-pyrano(3,2- c)pyridinderivate, verfahren zur herstellung und diese enthaltende pharmazeutische zusammenstellungen.
CA2100821A1 (en) Stereocontrolled Glycosidation
EP0118732A3 (en) An anthracycline compound, a process for the production thereof, a pharmaceutical composition containing the same and its use as a medicament
AU1015088A (en) New compounds, processes for their production and uses thereof
DE3572668D1 (en) Anthracycline derivatives, a process for the production thereof, a pharmaceutical composition containing the same and their use as medicaments
NO940304L (no) Fremgangsmåte for fermentering
NZ225055A (en) Composition for introducing hypersensitivity to gram-positive bacteria containing exoantigens of the bacteria, or their homologues
AU7134991A (en) Intermediates for use in process to produce 2',3' - dideoxynucleosides
GB8819758D0 (en) Production of 2-methyl-5-isopropyl-hexa-2,5-dien-1-al & of 2-methyl-5-isopropyl-hexa-2,4-dien-1-al in microorganisms
AU7250987A (en) Pharmaceutical compositions for use in improving oxygenation of the brain and a process for their production
ES2000916A6 (es) Procedimiento papra preparar derivados de antraciclina
HUT46366A (en) Process for the microbiological production of 1,2-dehydro-steroids