AU1395383A - Benzoazacycloalkyl-spiro-imidazolidines - Google Patents
Benzoazacycloalkyl-spiro-imidazolidinesInfo
- Publication number
- AU1395383A AU1395383A AU13953/83A AU1395383A AU1395383A AU 1395383 A AU1395383 A AU 1395383A AU 13953/83 A AU13953/83 A AU 13953/83A AU 1395383 A AU1395383 A AU 1395383A AU 1395383 A AU1395383 A AU 1395383A
- Authority
- AU
- Australia
- Prior art keywords
- benzoazacycloalkyl
- imidazolidines
- spiro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8207203A FR2525603A1 (fr) | 1982-04-27 | 1982-04-27 | Benzoazacycloalkyl-spiro-imidazolinines, leur preparation et leur application en therapeutique |
FR8207203 | 1982-04-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
AU1395383A true AU1395383A (en) | 1983-11-03 |
Family
ID=9273425
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU13953/83A Abandoned AU1395383A (en) | 1982-04-27 | 1983-04-26 | Benzoazacycloalkyl-spiro-imidazolidines |
Country Status (22)
Country | Link |
---|---|
JP (1) | JPS5910584A (el) |
KR (1) | KR840004428A (el) |
AT (1) | ATA125383A (el) |
AU (1) | AU1395383A (el) |
BE (1) | BE896572A (el) |
DD (1) | DD209833A5 (el) |
DE (1) | DE3315106A1 (el) |
DK (1) | DK183583A (el) |
ES (1) | ES8405796A1 (el) |
FR (1) | FR2525603A1 (el) |
GB (1) | GB2133401B (el) |
GR (1) | GR78481B (el) |
IL (1) | IL68497A0 (el) |
IT (1) | IT1167123B (el) |
LU (1) | LU84770A1 (el) |
MA (1) | MA19783A1 (el) |
NL (1) | NL8301476A (el) |
NO (1) | NO831473L (el) |
OA (1) | OA07412A (el) |
PT (1) | PT76595B (el) |
SE (1) | SE8302347L (el) |
ZA (1) | ZA832927B (el) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4927831A (en) * | 1988-10-20 | 1990-05-22 | American Home Products | Spiro-isoquinoline-pyrrolidine tetrones and analogs thereof useful as aldose reductase inhibitors |
AU617541B2 (en) * | 1988-10-20 | 1991-11-28 | Wyeth | Spiro-isoquinoline-pyrrolidine tetrones and analogs thereof useful as aldose reductase inhibitors |
US6953787B2 (en) | 2002-04-12 | 2005-10-11 | Arena Pharmaceuticals, Inc. | 5HT2C receptor modulators |
EA016558B1 (ru) | 2003-06-17 | 2012-05-30 | Арена Фармасьютикалз, Инк. | Производные бензазепина, используемые для лечения заболеваний, ассоциированных с 5-ht-рецептором |
HUE028976T2 (en) | 2003-06-17 | 2017-02-28 | Arena Pharm Inc | 8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride |
JP5270167B2 (ja) | 2004-12-21 | 2013-08-21 | アリーナ ファーマシューティカルズ, インコーポレイテッド | (r)−8−クロロ−1−メチル−2,3,4,5−テトラヒドロ−1h−3−ベンザゼピン塩酸塩の結晶形 |
CN102631349A (zh) | 2004-12-23 | 2012-08-15 | 艾尼纳制药公司 | 5HT2c受体调节剂组合物和使用方法 |
JP5199997B2 (ja) | 2006-04-03 | 2013-05-15 | アリーナ ファーマシューティカルズ, インコーポレイテッド | 8−クロロ−1−メチル−2,3,4,5−テトラヒドロ−1h−3−ベンズアゼピンおよびこれに関連する中間体を調製するためのプロセス |
CN101547892B (zh) | 2006-12-05 | 2014-08-20 | 艾尼纳制药公司 | 制备(r)-8-氯-1-甲基-2,3,4,5-四氢-1h-3-苯并氮杂卓的方法和其中间体 |
JP5491421B2 (ja) | 2008-03-04 | 2014-05-14 | アリーナ ファーマシューティカルズ, インコーポレイテッド | 5−ht2cアゴニストである(r)−8−クロロ−1−メチル−2,3,4,5−テトラヒドロ−1h−3−ベンゾアゼピンに関連する中間体の調製のためのプロセス |
WO2010148207A2 (en) | 2009-06-18 | 2010-12-23 | Arena Pharmaceuticals, Inc. | Processes for the preparation of 5-ht2c receptor agonists |
WO2011153206A1 (en) | 2010-06-02 | 2011-12-08 | Arena Pharmaceuticals, Inc. | Processes for the preparation of 5-ht2c receptor agonists |
EP2611433A2 (en) | 2010-09-01 | 2013-07-10 | Arena Pharmaceuticals, Inc. | Non-hygroscopic salts of 5-ht2c agonists |
SG10201506870PA (en) | 2010-09-01 | 2015-10-29 | Arena Pharm Inc | Salts of lorcaserin with optically active acids |
SG188362A1 (en) | 2010-09-01 | 2013-04-30 | Arena Pharm Inc | Modified-release dosage forms of 5-ht2c agonists useful for weight management |
US8999970B2 (en) | 2010-09-01 | 2015-04-07 | Arena Pharmaceuticals, Inc. | Administration of an anti-obesity compound to individuals with renal impairment |
KR20150070249A (ko) | 2012-10-09 | 2015-06-24 | 아레나 파마슈티칼스, 인크. | 체중 관리 방법 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4209630A (en) * | 1976-10-18 | 1980-06-24 | Pfizer Inc. | Hydantoin derivatives as therapeutic agents |
US4235911A (en) * | 1979-06-13 | 1980-11-25 | Pfizer Inc. | Hydantoin derivatives |
-
1982
- 1982-04-27 FR FR8207203A patent/FR2525603A1/fr active Granted
-
1983
- 1983-04-08 AT AT0125383A patent/ATA125383A/de not_active IP Right Cessation
- 1983-04-25 DD DD83250187A patent/DD209833A5/de unknown
- 1983-04-25 LU LU84770A patent/LU84770A1/fr unknown
- 1983-04-26 IL IL68497A patent/IL68497A0/xx unknown
- 1983-04-26 ZA ZA832927A patent/ZA832927B/xx unknown
- 1983-04-26 IT IT48155/83A patent/IT1167123B/it active
- 1983-04-26 KR KR1019830001753A patent/KR840004428A/ko not_active Application Discontinuation
- 1983-04-26 JP JP58073687A patent/JPS5910584A/ja active Pending
- 1983-04-26 SE SE8302347A patent/SE8302347L/xx not_active Application Discontinuation
- 1983-04-26 GR GR71214A patent/GR78481B/el unknown
- 1983-04-26 DK DK183583A patent/DK183583A/da not_active Application Discontinuation
- 1983-04-26 NO NO831473A patent/NO831473L/no unknown
- 1983-04-26 BE BE0/210633A patent/BE896572A/fr not_active IP Right Cessation
- 1983-04-26 NL NL8301476A patent/NL8301476A/nl not_active Application Discontinuation
- 1983-04-26 AU AU13953/83A patent/AU1395383A/en not_active Abandoned
- 1983-04-26 PT PT76595A patent/PT76595B/pt unknown
- 1983-04-27 DE DE19833315106 patent/DE3315106A1/de not_active Withdrawn
- 1983-04-27 ES ES521895A patent/ES8405796A1/es not_active Expired
- 1983-04-27 OA OA57984A patent/OA07412A/xx unknown
- 1983-04-27 MA MA20003A patent/MA19783A1/fr unknown
- 1983-04-27 GB GB08311508A patent/GB2133401B/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
FR2525603A1 (fr) | 1983-10-28 |
BE896572A (fr) | 1983-10-26 |
DK183583A (da) | 1983-10-28 |
IT8348155A0 (it) | 1983-04-26 |
DK183583D0 (da) | 1983-04-26 |
JPS5910584A (ja) | 1984-01-20 |
NL8301476A (nl) | 1983-11-16 |
KR840004428A (ko) | 1984-10-15 |
NO831473L (no) | 1983-10-28 |
MA19783A1 (fr) | 1983-12-31 |
GB8311508D0 (en) | 1983-06-02 |
ES521895A0 (es) | 1984-06-16 |
DD209833A5 (de) | 1984-05-23 |
DE3315106A1 (de) | 1983-11-03 |
IT1167123B (it) | 1987-05-13 |
ZA832927B (en) | 1984-06-27 |
GR78481B (el) | 1984-09-27 |
LU84770A1 (fr) | 1984-11-28 |
ES8405796A1 (es) | 1984-06-16 |
GB2133401B (en) | 1985-10-23 |
PT76595A (fr) | 1983-05-01 |
SE8302347D0 (sv) | 1983-04-26 |
PT76595B (fr) | 1986-01-21 |
IL68497A0 (en) | 1983-07-31 |
ATA125383A (de) | 1986-05-15 |
GB2133401A (en) | 1984-07-25 |
SE8302347L (sv) | 1983-10-28 |
FR2525603B1 (el) | 1984-09-14 |
OA07412A (fr) | 1984-11-30 |
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