AU1175076A - Indolylalkylpiperidines - Google Patents

Indolylalkylpiperidines

Info

Publication number
AU1175076A
AU1175076A AU11750/76A AU1175076A AU1175076A AU 1175076 A AU1175076 A AU 1175076A AU 11750/76 A AU11750/76 A AU 11750/76A AU 1175076 A AU1175076 A AU 1175076A AU 1175076 A AU1175076 A AU 1175076A
Authority
AU
Australia
Prior art keywords
piperidine
ethyl
compound
ethyleneureido
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU11750/76A
Other languages
English (en)
Inventor
Charles Ferdinand Huebner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of AU1175076A publication Critical patent/AU1175076A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Pyridine Compounds (AREA)
AU11750/76A 1975-03-10 1976-03-08 Indolylalkylpiperidines Expired AU1175076A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US55660075A 1975-03-10 1975-03-10

Publications (1)

Publication Number Publication Date
AU1175076A true AU1175076A (en) 1977-09-15

Family

ID=24222029

Family Applications (1)

Application Number Title Priority Date Filing Date
AU11750/76A Expired AU1175076A (en) 1975-03-10 1976-03-08 Indolylalkylpiperidines

Country Status (19)

Country Link
US (1) US4073911A (enExample)
JP (1) JPS51113878A (enExample)
AU (1) AU1175076A (enExample)
BE (1) BE839347A (enExample)
DD (1) DD124386A5 (enExample)
DE (1) DE2609289A1 (enExample)
DK (1) DK138893B (enExample)
ES (1) ES445874A1 (enExample)
FI (1) FI760584A7 (enExample)
FR (1) FR2303541A1 (enExample)
GB (1) GB1534351A (enExample)
GR (1) GR60030B (enExample)
IL (1) IL49171A (enExample)
NL (1) NL7602508A (enExample)
NO (1) NO760774L (enExample)
NZ (1) NZ180255A (enExample)
PT (1) PT64878B (enExample)
SE (1) SE7602729L (enExample)
ZA (2) ZA76475B (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4350634A (en) 1977-07-12 1982-09-21 Sandoz Ltd. N-Benzoyl-N'-3-indolyl-N'alkyl-1,3-diaminopropanes
GB1586817A (en) * 1977-12-01 1981-03-25 Wyeth John & Brother Ltd Indole derivatives
US4329348A (en) * 1979-02-26 1982-05-11 Ciba-Geigy Corporation N-Oxacyclic-alkylpiperidines as psychostimulants
US4359468A (en) * 1981-02-25 1982-11-16 Boehringer Ingelheim Ltd. Antiallergic N-[4-(indolyl)-piperidino-alkyl]-benzimidazolones
NZ216720A (en) * 1985-07-08 1990-09-26 Bristol Myers Co Diazinylpiperidine derivatives and pharmaceutical compositions
JP2807577B2 (ja) * 1990-06-15 1998-10-08 エーザイ株式会社 環状アミド誘導体
EP0640081B1 (en) * 1992-03-31 2000-01-12 Glaxo Group Limited Substituted phenylcarbamates and phenylureas, their preparation and their use as 5-ht4 antagonists
JP3916092B2 (ja) * 1993-09-17 2007-05-16 杏林製薬株式会社 イミダゾリジノン誘導体とその酸付加塩及び老年性痴呆症の治療薬
US6489300B1 (en) * 1997-07-31 2002-12-03 Eugene D. Thorsett Carbamyloxy compounds which inhibit leukocyte adhesion mediated by VLA-4
FR2803298A1 (fr) * 1999-12-30 2001-07-06 Adir Nouvelles urees lineaires ou cycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
AU2003248091A1 (en) * 2002-07-19 2004-02-09 Meiji Dairies Corporation Indole derivatives and drugs containing the same
WO2004091514A2 (en) * 2003-04-15 2004-10-28 Merck & Co., Inc. Cgrp receptor antagonists
US7476665B2 (en) * 2003-06-26 2009-01-13 Merck & Co., Inc. Benzodiazepine CGRP receptor antagonists
CN101124217A (zh) * 2004-01-29 2008-02-13 默克公司 Cgrp受体拮抗剂
WO2025183207A1 (ja) * 2024-02-28 2025-09-04 国立大学法人京都大学 がん免疫を活性化するスペルミジン誘導体

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3238215A (en) * 1963-10-17 1966-03-01 Sterling Drug Inc 1-[(3-, 2-, and 1-indolyl)-lower-alkyl-, lower-alkenyl-, and lower-alkynyl]piperidines
GB1273563A (en) * 1968-07-24 1972-05-10 Wyeth John & Brother Ltd Indoles

Also Published As

Publication number Publication date
ZA76475B (en) 1977-08-31
GR60030B (en) 1978-03-31
NZ180255A (en) 1978-07-10
DE2609289A1 (de) 1976-09-30
PT64878B (en) 1977-07-22
DD124386A5 (enExample) 1977-02-16
DK101476A (enExample) 1976-09-11
DK138893C (enExample) 1979-04-23
IL49171A (en) 1978-12-17
FR2303541A1 (fr) 1976-10-08
IL49171A0 (en) 1976-05-31
DK138893B (da) 1978-11-13
ES445874A1 (es) 1977-06-01
PT64878A (en) 1976-04-01
FR2303541B1 (enExample) 1979-10-05
US4073911A (en) 1978-02-14
NL7602508A (nl) 1976-09-14
SE7602729L (sv) 1976-09-13
FI760584A7 (enExample) 1976-09-11
NO760774L (enExample) 1976-09-13
BE839347A (fr) 1976-09-09
ZA761467B (en) 1977-10-26
JPS51113878A (en) 1976-10-07
GB1534351A (en) 1978-12-06

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