ATE965T1 - Aminopropanolderivate des 2-(o-hydroxyphenyl)-pyrrols, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen. - Google Patents
Aminopropanolderivate des 2-(o-hydroxyphenyl)-pyrrols, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen.Info
- Publication number
- ATE965T1 ATE965T1 AT79102837T AT79102837T ATE965T1 AT E965 T1 ATE965 T1 AT E965T1 AT 79102837 T AT79102837 T AT 79102837T AT 79102837 T AT79102837 T AT 79102837T AT E965 T1 ATE965 T1 AT E965T1
- Authority
- AT
- Austria
- Prior art keywords
- carbon atoms
- pyrrole
- hydroxyphenyl
- manufacture
- cycloalkyl
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- MXZROAOUCUVNHX-UHFFFAOYSA-N 2-Aminopropanol Chemical class CCC(N)O MXZROAOUCUVNHX-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 5
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- GKSPIKYEYHFEIS-UHFFFAOYSA-N 2-(1h-pyrrol-2-yl)phenol Chemical class OC1=CC=CC=C1C1=CC=CN1 GKSPIKYEYHFEIS-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 230000000747 cardiac effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000392 cycloalkenyl group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/333—Radicals substituted by oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19782835438 DE2835438A1 (de) | 1978-08-12 | 1978-08-12 | Aminopropanolderivate des 2-(o-hydroxyphenyl)-pyrrols |
| EP79102837A EP0008108B1 (de) | 1978-08-12 | 1979-08-07 | Aminopropanolderivate des 2-(o-Hydroxyphenyl)-pyrrols, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE965T1 true ATE965T1 (de) | 1982-05-15 |
Family
ID=6046918
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT79102837T ATE965T1 (de) | 1978-08-12 | 1979-08-07 | Aminopropanolderivate des 2-(o-hydroxyphenyl)-pyrrols, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4267187A (de) |
| EP (1) | EP0008108B1 (de) |
| JP (1) | JPS5527195A (de) |
| AT (1) | ATE965T1 (de) |
| DE (2) | DE2835438A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3343671A1 (de) * | 1983-12-02 | 1985-06-20 | Basf Ag, 6700 Ludwigshafen | Aminopropanolderivate von substituierten 2-hydroxy-propiophenonen, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel |
| EP0265388A1 (de) * | 1986-10-24 | 1988-04-27 | Ciba-Geigy Ag | Pyrrol-Derivate, therapeutische Mittel, die sie enthalten und ihre Verwendung |
| GB9325827D0 (en) * | 1993-12-17 | 1994-02-23 | Smithkline Beecham Plc | Compounds |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH575924A5 (en) * | 1973-03-09 | 1976-05-31 | Ciba Geigy Ag | Pyrrolylphenoxy propanolamine derivs - with anti-excitatory and adrenergic beta-receptor blocking activity |
| CH579045A5 (en) * | 1973-03-09 | 1976-08-31 | Ciba Geigy Ag | Pyrrolylphenoxy propanolamine derivs - with anti-excitatory and adrenergic beta-receptor blocking activity |
| CH575922A5 (en) * | 1973-03-09 | 1976-05-31 | Ciba Geigy Ag | Pyrrolylphenoxy propanolamine derivs - with anti-excitatory and adrenergic beta-receptor blocking activity |
| CH579046A5 (en) * | 1973-03-09 | 1976-08-31 | Ciba Geigy Ag | Pyrrolylphenoxy propanolamine derivs - with anti-excitatory and adrenergic beta-receptor blocking activity |
| CH575923A5 (en) * | 1973-03-09 | 1976-05-31 | Ciba Geigy Ag | Pyrrolylphenoxy propanolamine derivs - with anti-excitatory and adrenergic beta-receptor blocking activity |
-
1978
- 1978-08-12 DE DE19782835438 patent/DE2835438A1/de active Pending
-
1979
- 1979-08-07 DE DE7979102837T patent/DE2962700D1/de not_active Expired
- 1979-08-07 AT AT79102837T patent/ATE965T1/de not_active IP Right Cessation
- 1979-08-07 EP EP79102837A patent/EP0008108B1/de not_active Expired
- 1979-08-08 US US06/064,907 patent/US4267187A/en not_active Expired - Lifetime
- 1979-08-13 JP JP10229579A patent/JPS5527195A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0008108B1 (de) | 1982-05-05 |
| EP0008108A3 (en) | 1980-03-05 |
| DE2835438A1 (de) | 1980-03-06 |
| DE2962700D1 (en) | 1982-06-24 |
| JPS5527195A (en) | 1980-02-27 |
| US4267187A (en) | 1981-05-12 |
| EP0008108A2 (de) | 1980-02-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee |