ATE94560T1 - L-prolin-derivate, deren herstellung und deren biologische anwendungen. - Google Patents
L-prolin-derivate, deren herstellung und deren biologische anwendungen.Info
- Publication number
- ATE94560T1 ATE94560T1 AT88402761T AT88402761T ATE94560T1 AT E94560 T1 ATE94560 T1 AT E94560T1 AT 88402761 T AT88402761 T AT 88402761T AT 88402761 T AT88402761 T AT 88402761T AT E94560 T1 ATE94560 T1 AT E94560T1
- Authority
- AT
- Austria
- Prior art keywords
- derivatives
- group
- production
- alkyl
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Psychiatry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Protection Of Transformers (AREA)
- Measurement Of Force In General (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8715228A FR2622581B1 (fr) | 1987-11-03 | 1987-11-03 | Nouveaux derives de l-proline, leur preparation et leurs applications biologiques |
EP88402761A EP0316218B1 (de) | 1987-11-03 | 1988-11-03 | L-Prolin-Derivate, deren Herstellung und deren biologische Anwendungen |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE94560T1 true ATE94560T1 (de) | 1993-10-15 |
Family
ID=9356437
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT88402761T ATE94560T1 (de) | 1987-11-03 | 1988-11-03 | L-prolin-derivate, deren herstellung und deren biologische anwendungen. |
Country Status (12)
Country | Link |
---|---|
US (1) | US5212158A (de) |
EP (1) | EP0316218B1 (de) |
JP (1) | JP2694191B2 (de) |
KR (1) | KR0121793B1 (de) |
AT (1) | ATE94560T1 (de) |
CA (1) | CA1340227C (de) |
DE (1) | DE3884139T2 (de) |
ES (1) | ES2061710T3 (de) |
FI (1) | FI885083A (de) |
FR (1) | FR2622581B1 (de) |
IE (1) | IE64509B1 (de) |
IL (1) | IL88275A0 (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0445606B1 (de) * | 1990-02-27 | 1997-01-22 | The Agency of Industrial Science and Technology | Oligopeptide, sie enthaltende pharmazeutische und Futterzusammensetzung und Benützung von Oligopeptiden |
JP3343181B2 (ja) * | 1995-09-20 | 2002-11-11 | 生化学工業株式会社 | 桂皮酸誘導体 |
US7671029B2 (en) * | 1999-08-06 | 2010-03-02 | Immupharma Sa | Compositions and methods for enhanced pharmacological activity of compositions comprising peptide drug substances |
US6908900B2 (en) * | 2001-01-17 | 2005-06-21 | Zimmer & Associates Ag | Compositions and methods for enhanced pharmacological activity through oral and parenteral administration of compositions comprising polypeptide drug substances and other poorly absorbed active ingredients |
US20050192228A1 (en) * | 2001-02-05 | 2005-09-01 | Jean Rapin | Tripeptide derivatives for the treatment of neurodegenerative diseases |
DE10105040A1 (de) * | 2001-02-05 | 2002-08-14 | Tell Pharm Ag Hergiswil | Tripeptid-Derivate für die Behandlung von postläsionalen Krankheiten des Nervensystems |
DE10105041A1 (de) * | 2001-02-05 | 2002-08-14 | Tell Pharm Ag Hergiswil | Tripeptide und Tripeptid-Derivate für die Behandlung neurodegenerativer Krankheiten |
DE10105039A1 (de) * | 2001-02-05 | 2002-08-08 | Tell Pharm Ag Hergiswil | Tripeptid-Derivate für die Behandlung neurodegenerativer Krankheiten |
DE10105038B4 (de) | 2001-02-05 | 2005-07-07 | Neurotell Ag | Tripeptid-Derivate für die Behandlung von postläsionalen Krankheiten des Nervensystems |
WO2003020321A2 (en) * | 2001-09-06 | 2003-03-13 | Zimmer Robert H | Derivatives of pseudo-peptides, their preparation and their biological uses |
US7252446B2 (en) * | 2004-03-31 | 2007-08-07 | Brother Kogoy Kabushiki Kaisha | Image forming apparatus |
FR2932179B1 (fr) | 2008-06-09 | 2012-12-07 | I R D | Procede microbiologique de synthese de derives cinnamoyl amides d'acides amines |
UY32827A (es) * | 2009-08-12 | 2011-02-28 | Glaxo Group Ltd | Inhibidores de catepsina c |
SG192669A1 (en) | 2011-02-11 | 2013-09-30 | Glaxosmithkline Ip Dev Ltd | Cathepsin c inhibitors |
US20160045473A1 (en) * | 2012-08-01 | 2016-02-18 | Rory Powell Blake | Biological Basis Of Adult Wellness |
US20150038547A1 (en) * | 2013-07-31 | 2015-02-05 | Rory Powell Blake | Biological Basis of Adult Wellness |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1523598A (en) * | 1975-03-08 | 1978-09-06 | Reckitt & Colmann Prod Ltd | Tripeptides |
US4260682A (en) * | 1979-04-04 | 1981-04-07 | Ryan James W | High sensitivity assays for angiotensin converting enzyme |
WO1982000641A1 (en) * | 1980-08-25 | 1982-03-04 | Ab Kabivitrum | Peptide substrates for determination of protease activity |
US4499079A (en) * | 1982-11-18 | 1985-02-12 | E. R. Squibb & Sons, Inc. | Carboxy and substituted carboxy alkanoyl and cycloalkanoyl peptides |
EP0124317B1 (de) * | 1983-04-27 | 1990-04-11 | Ici Americas Inc. | Prolin-Derivate |
JPS63112597A (ja) * | 1986-10-29 | 1988-05-17 | Tokuyama Soda Co Ltd | アミノ酸誘導体 |
US4804743A (en) * | 1987-01-29 | 1989-02-14 | Warner-Lambert Copmany | Proline-containing renin inhibitors |
-
1987
- 1987-11-03 FR FR8715228A patent/FR2622581B1/fr not_active Expired - Lifetime
-
1988
- 1988-11-02 JP JP63276343A patent/JP2694191B2/ja not_active Expired - Fee Related
- 1988-11-03 US US07/266,680 patent/US5212158A/en not_active Expired - Lifetime
- 1988-11-03 IL IL88275A patent/IL88275A0/xx not_active IP Right Cessation
- 1988-11-03 CA CA000582169A patent/CA1340227C/fr not_active Expired - Fee Related
- 1988-11-03 ES ES88402761T patent/ES2061710T3/es not_active Expired - Lifetime
- 1988-11-03 AT AT88402761T patent/ATE94560T1/de not_active IP Right Cessation
- 1988-11-03 DE DE88402761T patent/DE3884139T2/de not_active Expired - Lifetime
- 1988-11-03 IE IE332188A patent/IE64509B1/en not_active IP Right Cessation
- 1988-11-03 EP EP88402761A patent/EP0316218B1/de not_active Expired - Lifetime
- 1988-11-03 KR KR1019880014433A patent/KR0121793B1/ko not_active IP Right Cessation
- 1988-11-03 FI FI885083A patent/FI885083A/fi not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DE3884139D1 (de) | 1993-10-21 |
FR2622581A1 (fr) | 1989-05-05 |
KR0121793B1 (ko) | 1997-11-27 |
FI885083A (fi) | 1989-05-04 |
ES2061710T3 (es) | 1994-12-16 |
FR2622581B1 (fr) | 1990-02-16 |
US5212158A (en) | 1993-05-18 |
KR890008091A (ko) | 1989-07-08 |
EP0316218A1 (de) | 1989-05-17 |
IL88275A0 (en) | 1989-06-30 |
FI885083A0 (fi) | 1988-11-03 |
JPH01157998A (ja) | 1989-06-21 |
IE64509B1 (en) | 1995-08-09 |
IE883321L (en) | 1989-05-03 |
CA1340227C (fr) | 1998-12-15 |
EP0316218B1 (de) | 1993-09-15 |
DE3884139T2 (de) | 1994-05-05 |
JP2694191B2 (ja) | 1997-12-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
EEIH | Change in the person of patent owner | ||
EEIH | Change in the person of patent owner | ||
EEFA | Change of the company name | ||
EELA | Cancelled due to lapse of time |