ATE93516T1 - Verfahren zur resolution von threo-3-((2aminophenyl)-thio>-2-hydroxy-3-(4-methoxyphenyl)propions|ure. - Google Patents

Verfahren zur resolution von threo-3-((2aminophenyl)-thio>-2-hydroxy-3-(4-methoxyphenyl)propions|ure.

Info

Publication number
ATE93516T1
ATE93516T1 AT90909482T AT90909482T ATE93516T1 AT E93516 T1 ATE93516 T1 AT E93516T1 AT 90909482 T AT90909482 T AT 90909482T AT 90909482 T AT90909482 T AT 90909482T AT E93516 T1 ATE93516 T1 AT E93516T1
Authority
AT
Austria
Prior art keywords
threo
thio
methoxyphenyl
hydroxy
resolution
Prior art date
Application number
AT90909482T
Other languages
English (en)
Inventor
Elemer Fogassy
Maria Acs
Tibor Gizur
Kalman Harsanyi
Tischler Zsuzsanna Aracsne
Katalin Berki
Laszlo Toeke
Jaszay Zsuzsa Martonffyne
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU333589A external-priority patent/HU205896B/hu
Priority claimed from HU333689A external-priority patent/HU204774B/hu
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Application granted granted Critical
Publication of ATE93516T1 publication Critical patent/ATE93516T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/26—Separation; Purification; Stabilisation; Use of additives
    • C07C319/28—Separation; Purification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT90909482T 1989-06-30 1990-06-29 Verfahren zur resolution von threo-3-((2aminophenyl)-thio>-2-hydroxy-3-(4-methoxyphenyl)propions|ure. ATE93516T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
HU333589A HU205896B (en) 1989-06-30 1989-06-30 Process for resolving treo-3-//2-amino-phenyl/-thio/-2-hydroxy-3-/4-methoxy-phenyl/-propionic acid
HU333689A HU204774B (en) 1989-06-30 1989-06-30 Process for resolving alpha-phenylglycineamide
PCT/HU1990/000045 WO1991000270A1 (en) 1989-06-30 1990-06-29 Process for the resolution of threo-3-[(2-aminophenyl)-thio]-2-hydroxy-3-(4-methoxy-phenyl)propionic acid
EP90909482A EP0431121B1 (de) 1989-06-30 1990-06-29 Verfahren zur resolution von threo-3-[(2-aminophenyl)-thio]-2-hydroxy-3-(4-methoxy-phenyl)propionsäure

Publications (1)

Publication Number Publication Date
ATE93516T1 true ATE93516T1 (de) 1993-09-15

Family

ID=26317626

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90909482T ATE93516T1 (de) 1989-06-30 1990-06-29 Verfahren zur resolution von threo-3-((2aminophenyl)-thio>-2-hydroxy-3-(4-methoxyphenyl)propions|ure.

Country Status (10)

Country Link
US (1) US5292933A (de)
EP (1) EP0431121B1 (de)
JP (1) JPH04500528A (de)
AT (1) ATE93516T1 (de)
DE (1) DE69002924T2 (de)
DK (1) DK0431121T3 (de)
ES (1) ES2060180T3 (de)
IE (1) IE62410B1 (de)
IL (1) IL94914A (de)
WO (1) WO1991000270A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1240651B (it) * 1990-05-17 1993-12-17 Zambon Spa Processo per la risoluzione di derivati glicidici
MX2021011484A (es) * 2019-03-22 2021-11-12 Tyme Inc Composiciones de d-metirosina y metodos para preparar las mismas.
EA202193111A1 (ru) 2019-05-14 2022-02-10 Тайм, Инк. Композиции и способы для лечения рака
US10905698B1 (en) 2020-05-14 2021-02-02 Tyme, Inc. Methods of treating SARS-COV-2 infections
EP4175938A1 (de) * 2020-07-01 2023-05-10 Tyme, Inc. Kristalline formen von metyrosin

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7413843A (nl) * 1974-10-23 1976-04-27 Stamicarbon Optische scheiding van fenylglycine-amide.
SE449611B (sv) * 1982-07-09 1987-05-11 Tanabe Seiyaku Co Sett att framstella 1,5-bensotiazepinderivat
IT1152721B (it) * 1982-10-15 1987-01-07 Luso Farmaco Inst Risoluzione ottica dell'acido dl-alfa-2-idrossi-3-(4-metossifenil)-3-(2-amminofeniltio)propionico
EP0320532A1 (de) * 1986-07-15 1989-06-21 Nihon Iyakuhin Kogyo Co., Ltd. Optisch aktives Carbonsäurederivat-l-Lysinsalz und Verfahren zu dessen Herstellung
IT1217988B (it) * 1988-01-28 1990-03-30 Ind Chimica Profarmaco Spa Procedimento per la risoluzione ottica di un pacemo
FR2630107B1 (fr) * 1988-04-19 1990-06-08 Synthelabo Procede de preparation du (+) - (2s,3s) (amino-2 phenyl)thio)-3 hydroxy-2 (methoxy-4 phenyl)-3 propionate de methyle
US5008433A (en) * 1988-05-18 1991-04-16 Marion Laboratories, Inc. 2-hydroxy-3-(4-methoxyphenyl)-3-(2-aminophenylthio)propionic acid, 8'-phenylmenthyl ester, especially for diltiazem
FR2637285B1 (fr) * 1988-10-03 1991-04-12 Synthelabo Procede de preparation de derives de l'acide propionique et produits obtenus

Also Published As

Publication number Publication date
EP0431121A1 (de) 1991-06-12
DE69002924D1 (en) 1993-09-30
WO1991000270A1 (en) 1991-01-10
IE902360L (en) 1990-12-30
IE62410B1 (en) 1995-01-25
IL94914A0 (en) 1991-04-15
US5292933A (en) 1994-03-08
DK0431121T3 (da) 1993-10-11
ES2060180T3 (es) 1994-11-16
DE69002924T2 (de) 1993-12-23
IL94914A (en) 1994-07-31
EP0431121B1 (de) 1993-08-25
IE902360A1 (en) 1991-06-19
JPH04500528A (ja) 1992-01-30

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee