ATE89550T1 - Phenylsulfon-derivate. - Google Patents
Phenylsulfon-derivate.Info
- Publication number
- ATE89550T1 ATE89550T1 AT90902305T AT90902305T ATE89550T1 AT E89550 T1 ATE89550 T1 AT E89550T1 AT 90902305 T AT90902305 T AT 90902305T AT 90902305 T AT90902305 T AT 90902305T AT E89550 T1 ATE89550 T1 AT E89550T1
- Authority
- AT
- Austria
- Prior art keywords
- derivative
- novel
- derivatives
- phenylsulfone
- aminophenylsulphone
- Prior art date
Links
- KZTYYGOKRVBIMI-UHFFFAOYSA-N diphenyl sulfone Chemical class C=1C=CC=CC=1S(=O)(=O)C1=CC=CC=C1 KZTYYGOKRVBIMI-UHFFFAOYSA-N 0.000 title 1
- MYEWQUYMRFSJHT-UHFFFAOYSA-N 2-(2-aminophenyl)sulfonylaniline Chemical class NC1=CC=CC=C1S(=O)(=O)C1=CC=CC=C1N MYEWQUYMRFSJHT-UHFFFAOYSA-N 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 102000016912 Aldehyde Reductase Human genes 0.000 abstract 1
- 108010053754 Aldehyde reductase Proteins 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C317/34—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
- C07C317/36—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring with the nitrogen atoms of the amino groups bound to hydrogen atoms or to carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C317/34—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
- C07C317/38—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring with the nitrogen atom of at least one amino group being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfones
- C07C317/40—Y being a hydrogen or a carbon atom
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Luminescent Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/306,676 US5153227A (en) | 1987-08-06 | 1989-02-06 | Phenylsulfonyl nitromethanes as aldose reductase inhibitors |
| PCT/GB1990/000150 WO1990008761A1 (en) | 1989-02-06 | 1990-02-02 | Phenylsulphone derivatives |
| EP90902305A EP0408713B1 (de) | 1989-02-06 | 1990-02-02 | Phenylsulfon-derivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE89550T1 true ATE89550T1 (de) | 1993-06-15 |
Family
ID=23186342
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90902305T ATE89550T1 (de) | 1989-02-06 | 1990-02-02 | Phenylsulfon-derivate. |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0408713B1 (de) |
| JP (1) | JP3056245B2 (de) |
| KR (1) | KR910700232A (de) |
| AT (1) | ATE89550T1 (de) |
| AU (1) | AU630151B2 (de) |
| CA (1) | CA2026003A1 (de) |
| DE (1) | DE69001650T2 (de) |
| DK (1) | DK0408713T3 (de) |
| ES (1) | ES2055416T3 (de) |
| FI (1) | FI904891A7 (de) |
| GB (1) | GB2227745B (de) |
| GR (1) | GR1000423B (de) |
| HU (1) | HU206674B (de) |
| IE (1) | IE63463B1 (de) |
| IL (1) | IL93225A (de) |
| NO (1) | NO173822C (de) |
| NZ (1) | NZ232293A (de) |
| PT (1) | PT93064B (de) |
| RU (2) | RU1817776C (de) |
| WO (1) | WO1990008761A1 (de) |
| ZA (1) | ZA90674B (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9016980D0 (en) * | 1990-08-02 | 1990-09-19 | Ici Plc | Amidobenzenes |
| US5250570A (en) * | 1990-08-02 | 1993-10-05 | Imperial Chemical Industries Plc | Amidobenzene derivatives, compositions and use |
| GB9016978D0 (en) * | 1990-08-02 | 1990-09-19 | Ici Plc | Acetamide derivatives |
| FR2757509B1 (fr) * | 1996-12-23 | 1999-03-26 | Lipha | Nouveaux derives de sulfonamides et sulfonylurees, leurs preparations et medicaments les contenant |
| US5932765A (en) * | 1997-05-23 | 1999-08-03 | Merck Patent Gesellschaft Mit | Nitromethyl ketones, process for preparing them and compositions containing them |
| NZ503796A (en) * | 1997-10-20 | 2001-11-30 | Dainippon Pharmaceutical Co | Fast-dissolving pharmaceutical composition comprising micronised (R)-2-(4-bromo-2-fluorobenzyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-4-spiro-3'-pyrrolidine-1,2',3,5'-tetrone (AS-3201) |
| DK0974356T3 (da) * | 1998-07-15 | 2003-10-27 | Merck Sante Sas | Tabletter omfattende en kombination af metformin og glibenclamid |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8718619D0 (en) * | 1987-08-06 | 1987-09-09 | Ici Plc | Pharmaceutical compositions |
| DE3727468A1 (de) * | 1987-08-18 | 1989-03-02 | Kolbenschmidt Ag | Verbundgleitlager |
-
1990
- 1990-01-25 IE IE28890A patent/IE63463B1/en not_active IP Right Cessation
- 1990-01-30 NZ NZ232293A patent/NZ232293A/en unknown
- 1990-01-30 IL IL9322590A patent/IL93225A/en not_active IP Right Cessation
- 1990-01-30 ZA ZA90674A patent/ZA90674B/xx unknown
- 1990-02-02 HU HU901209A patent/HU206674B/hu not_active IP Right Cessation
- 1990-02-02 ES ES90902305T patent/ES2055416T3/es not_active Expired - Lifetime
- 1990-02-02 DE DE9090902305T patent/DE69001650T2/de not_active Expired - Fee Related
- 1990-02-02 AU AU49538/90A patent/AU630151B2/en not_active Ceased
- 1990-02-02 AT AT90902305T patent/ATE89550T1/de not_active IP Right Cessation
- 1990-02-02 JP JP2502383A patent/JP3056245B2/ja not_active Expired - Lifetime
- 1990-02-02 FI FI904891A patent/FI904891A7/fi not_active Application Discontinuation
- 1990-02-02 CA CA002026003A patent/CA2026003A1/en not_active Abandoned
- 1990-02-02 WO PCT/GB1990/000150 patent/WO1990008761A1/en not_active Ceased
- 1990-02-02 DK DK90902305.3T patent/DK0408713T3/da active
- 1990-02-02 GB GB9002373A patent/GB2227745B/en not_active Expired - Lifetime
- 1990-02-02 EP EP90902305A patent/EP0408713B1/de not_active Expired - Lifetime
- 1990-02-05 PT PT93064A patent/PT93064B/pt not_active IP Right Cessation
- 1990-02-05 GR GR900100069A patent/GR1000423B/el unknown
- 1990-10-05 NO NO904335A patent/NO173822C/no unknown
- 1990-10-05 RU SU904831294A patent/RU1817776C/ru active
- 1990-10-08 KR KR1019900702229A patent/KR910700232A/ko not_active Abandoned
-
1992
- 1992-03-16 RU SU925011613A patent/RU2034834C1/ru active
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |