ATE89276T1 - ((aryl-4-piperazinyl-1)-2-ethoxy>-3p-cymole, die ortho-, meta-, para-monosubstituierten oder disubstituierten derivate, das verfahren zu deren herstellung und die als aktives prinzip diese verbindungen enthaltenden arzneimittel. - Google Patents
((aryl-4-piperazinyl-1)-2-ethoxy>-3p-cymole, die ortho-, meta-, para-monosubstituierten oder disubstituierten derivate, das verfahren zu deren herstellung und die als aktives prinzip diese verbindungen enthaltenden arzneimittel.Info
- Publication number
- ATE89276T1 ATE89276T1 AT89401640T AT89401640T ATE89276T1 AT E89276 T1 ATE89276 T1 AT E89276T1 AT 89401640 T AT89401640 T AT 89401640T AT 89401640 T AT89401640 T AT 89401640T AT E89276 T1 ATE89276 T1 AT E89276T1
- Authority
- AT
- Austria
- Prior art keywords
- cymole
- monosubstituted
- piperazinyl
- ortho
- para
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/112—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8807864A FR2632641B1 (fr) | 1988-06-13 | 1988-06-13 | ((aryl-4-piperazinyl-1)-2 ethoxy)-3 p-cymene, les derives ortho, meta, para monosubstitues ou disubstitues sur le noyau phenyle dudit produit, le procede de preparation desdits derives, et les medicaments contenant lesdits composes comme principe actif |
EP89401640A EP0347305B1 (de) | 1988-06-13 | 1989-06-13 | [(Aryl-4-piperazinyl-1)-2-ethoxy]-3p-cymole, die ortho-, meta-, para-monosubstituierten oder disubstituierten Derivate, das Verfahren zu deren Herstellung und die als aktives Prinzip diese Verbindungen enthaltenden Arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE89276T1 true ATE89276T1 (de) | 1993-05-15 |
Family
ID=9367221
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT89401640T ATE89276T1 (de) | 1988-06-13 | 1989-06-13 | ((aryl-4-piperazinyl-1)-2-ethoxy>-3p-cymole, die ortho-, meta-, para-monosubstituierten oder disubstituierten derivate, das verfahren zu deren herstellung und die als aktives prinzip diese verbindungen enthaltenden arzneimittel. |
Country Status (8)
Country | Link |
---|---|
US (1) | US5110816A (de) |
EP (2) | EP0445116A1 (de) |
JP (1) | JPH03505456A (de) |
AT (1) | ATE89276T1 (de) |
DE (1) | DE68906466T2 (de) |
DK (1) | DK168071B1 (de) |
FR (1) | FR2632641B1 (de) |
WO (1) | WO1989012634A1 (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4410822A1 (de) * | 1994-03-24 | 1995-09-28 | Schering Ag | Neue Piperidin-Derivate |
ES2160158T3 (es) | 1994-03-30 | 2001-11-01 | Zeria Pharm Co Ltd | Derivados de 4-indol-1-il acido butirico, su preparacion y su utilizacion como inhibidores de receptores alfa1-adrenergicos y testosterona 5alfa-reductasas. |
ES2239766T3 (es) * | 1995-01-23 | 2005-10-01 | Daiichi Suntory Pharma Co., Ltd. | Alivio o remedio para sintomas causados por enfermedades isquemicas y compuestos de fenilpiperidina utilizados para ello. |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1349636A (fr) * | 1962-02-26 | 1964-01-17 | Soc Ind Fab Antibiotiques Sifa | Nouveaux dérivés de la pipérazine, et procédé de préparation |
CA967965A (en) * | 1968-12-24 | 1975-05-20 | Hoffmann-La Roche Limited | Aromatic ethers and process for the manufacture thereof |
FR2515647A1 (fr) * | 1981-11-03 | 1983-05-06 | Cortial | Nouvelles imines derivees de (phenyl-4 piperazinylethyl)-2 anilines, leur methode de preparation et leur application therapeutique |
FR2515648A1 (fr) * | 1981-11-03 | 1983-05-06 | Cortial | Nouvelles (phenyl-4 piperazinylethyl)-2 anilines, leur methode de preparation et leur application therapeutique |
FR2568878B1 (fr) * | 1984-08-07 | 1986-11-21 | Cortial | Nouveaux derives de (phenylpiperazinylethylamine ethoxy)-4 phenol, leur methode de preparation et leur application therapeutique |
EP0173634B1 (de) * | 1984-08-07 | 1988-08-31 | Cortial S.A. | 4-(Arylpiperazinylethylaminoethoxy)-phenolderivate, Verfahren zu deren Herstellung und deren therapeutische Verwendung |
EP0179009A1 (de) * | 1984-09-19 | 1986-04-23 | Cortial S.A. | N-1(Aminoalcoxy)-4-isopropyl-5 phenoxy)-2 ethyl-N-4-phenylpiperazine, Verfahren zu ihrer Herstellung und ihre therapeutische Verwendung |
DE3604941A1 (de) * | 1986-02-17 | 1987-08-20 | Heumann Pharma Gmbh & Co | Phenylpiperazinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
FR2595357B1 (fr) * | 1986-03-04 | 1988-07-08 | Irceba | (piperidino-3 propoxy)-5 p.cymene, les derives acetyl, acetoxy et hydroxy dudit produit, les sels de ces produits, un procede de preparation desdits produits et les medicaments contenant au moins un de ces produits comme principe actif |
-
1988
- 1988-06-13 FR FR8807864A patent/FR2632641B1/fr not_active Expired - Lifetime
-
1989
- 1989-06-13 AT AT89401640T patent/ATE89276T1/de active
- 1989-06-13 EP EP89907194A patent/EP0445116A1/de active Pending
- 1989-06-13 JP JP1507008A patent/JPH03505456A/ja active Pending
- 1989-06-13 EP EP89401640A patent/EP0347305B1/de not_active Expired - Lifetime
- 1989-06-13 DE DE8989401640T patent/DE68906466T2/de not_active Expired - Fee Related
- 1989-06-13 US US07/623,718 patent/US5110816A/en not_active Expired - Fee Related
- 1989-06-13 WO PCT/FR1989/000298 patent/WO1989012634A1/fr not_active Application Discontinuation
-
1990
- 1990-12-11 DK DK293890A patent/DK168071B1/da not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
WO1989012634A1 (fr) | 1989-12-28 |
DE68906466T2 (de) | 1993-09-09 |
DK293890D0 (da) | 1990-12-11 |
DK168071B1 (da) | 1994-01-31 |
EP0347305A1 (de) | 1989-12-20 |
EP0347305B1 (de) | 1993-05-12 |
FR2632641A1 (fr) | 1989-12-15 |
DE68906466D1 (de) | 1993-06-17 |
FR2632641B1 (fr) | 1990-10-12 |
DK293890A (da) | 1990-12-11 |
EP0445116A1 (de) | 1991-09-11 |
JPH03505456A (ja) | 1991-11-28 |
US5110816A (en) | 1992-05-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FR2382441A1 (fr) | Nouveaux n-(aminoalkyl substitue)-2-oxo-1-pyrrolidine-acetamides utiles en tant que medicaments et procedes pour leur preparation | |
PT77110B (fr) | Procede de preparation de nouveaux derives de la xanthine | |
ATE8144T1 (de) | Indolobenzoxazine, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische zusammensetzungen. | |
ATE89276T1 (de) | ((aryl-4-piperazinyl-1)-2-ethoxy>-3p-cymole, die ortho-, meta-, para-monosubstituierten oder disubstituierten derivate, das verfahren zu deren herstellung und die als aktives prinzip diese verbindungen enthaltenden arzneimittel. | |
ATE73445T1 (de) | 1,2,5,6-tetrahydropyridinoxim-derivate, verfahren zu deren herstellung, deren verwendung als arzneimittel und diese enthaltende zusammensetzungen. | |
DE68912263D1 (de) | 4-Methyl-5[2-(4-phenyl-1-piperazinyl)-ethyl]-Thiazolderivate, ihre Herstellung und Zusammenstellungen, die sie enthalten. | |
ATE25849T1 (de) | Tricyclophosphazen-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel. | |
ATE71938T1 (de) | 1,2,5,6-tetrahydropyridin-3-carboxaldehydoximderivate, verfahren zu deren herstellung, deren verwendung als arzneimittel und diese enthaltende zusammensetzungen. | |
ATE417831T1 (de) | Ceramid ähnliche verbindungen, verfahren zu deren herstellung und deren verwendung als antitumormittel | |
ATE214375T1 (de) | Piperazinylalkylthiopyrimidin derivate, diese enthaltende pharmazeutische zusammensetzungen und verfahren zu deren herstellung | |
ATE19244T1 (de) | 2-piperazinyl-4-phenyl-quinazolin-derivate mit antidepressiven eigenschaften, verfahren zu deren herstellung und diese enthaltende arzneimitteln. | |
ES8407023A1 (es) | Un procedimiento para la preparacion de 4-(3-trifluormetilfenil-1,2,3,6-tetrahidropiridinas | |
DE3381892D1 (de) | 4-(1-(phenyl)-1-(hydroxy)-prop-1-yl)-resorcinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel. | |
ATE55611T1 (de) | 2,2;6,6-diethylen-3-oxo-17alpha-pregn-4-en-21, 17-carbolactone, verfahren zu deren herstellung und diese enthaltende pharm. praeparate. | |
DE69006338D1 (de) | Neue Derivate substituierter Verfahren zu deren Herstellung und pharmazeutische Zubereitungen, die sie enthalten. | |
OA08813A (fr) | Nouveaux dérivés de l'acide (dihydro-2,3, oxo-2 benzofurannyl-3)-2 acétique, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent. | |
DK0865422T3 (da) | Anvendelse af aminoalkoholderivater som lægemidler, hidtil ukendte derivater og fremgangsmåde til fremstilling deraf | |
DE3860117D1 (de) | 2,3-dihydro-3-phenyl-benzofuran-2-on-acetamidderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel. | |
BG50776A1 (en) | Derivatives of n- (2- phenylmorpholinomethyl)- succinamide and method for their preparation | |
KR890014535A (ko) | 인돌화합물 및 이들의 제조방법, 및 이들 화합물을 함유하는 약학적 조성물 | |
GB2316406A (en) | Free radical scavenger molecules |