ATE84708T1 - Antacidzusammensetzungen mit laengerer verweilzeit im magen. - Google Patents
Antacidzusammensetzungen mit laengerer verweilzeit im magen.Info
- Publication number
- ATE84708T1 ATE84708T1 AT89304013T AT89304013T ATE84708T1 AT E84708 T1 ATE84708 T1 AT E84708T1 AT 89304013 T AT89304013 T AT 89304013T AT 89304013 T AT89304013 T AT 89304013T AT E84708 T1 ATE84708 T1 AT E84708T1
- Authority
- AT
- Austria
- Prior art keywords
- stomach
- antacid
- longer time
- antacid compositions
- solid
- Prior art date
Links
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical class [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 title abstract 3
- 229940069428 antacid Drugs 0.000 title abstract 3
- 239000003159 antacid agent Substances 0.000 title abstract 3
- 230000001458 anti-acid effect Effects 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title 1
- 210000002784 stomach Anatomy 0.000 title 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 3
- IPCSVZSSVZVIGE-UHFFFAOYSA-N hexadecanoic acid Chemical compound CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 abstract 2
- 239000007787 solid Substances 0.000 abstract 2
- 235000021314 Palmitic acid Nutrition 0.000 abstract 1
- 235000021355 Stearic acid Nutrition 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 230000002209 hydrophobic effect Effects 0.000 abstract 1
- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 abstract 1
- 239000012875 nonionic emulsifier Substances 0.000 abstract 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 abstract 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 229920000098 polyolefin Polymers 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
- 239000008117 stearic acid Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/08—Oxides; Hydroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Inorganic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB888809421A GB8809421D0 (en) | 1988-04-21 | 1988-04-21 | Antacid compositions with prolonged gastric residence time |
| EP89304013A EP0338861B1 (de) | 1988-04-21 | 1989-04-21 | Antacidzusammensetzungen mit längerer Verweilzeit im Magen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE84708T1 true ATE84708T1 (de) | 1993-02-15 |
Family
ID=10635574
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89304013T ATE84708T1 (de) | 1988-04-21 | 1989-04-21 | Antacidzusammensetzungen mit laengerer verweilzeit im magen. |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5288506A (de) |
| EP (1) | EP0338861B1 (de) |
| JP (1) | JPH0764724B2 (de) |
| KR (1) | KR950007205B1 (de) |
| AT (1) | ATE84708T1 (de) |
| AU (1) | AU616257B2 (de) |
| CA (1) | CA1336495C (de) |
| DE (1) | DE68904459T2 (de) |
| DK (1) | DK188489A (de) |
| ES (1) | ES2044099T3 (de) |
| FI (1) | FI98886C (de) |
| GB (1) | GB8809421D0 (de) |
| GR (1) | GR3006908T3 (de) |
| HU (1) | HU211236A9 (de) |
| IE (1) | IE61866B1 (de) |
| NO (1) | NO176868C (de) |
| NZ (1) | NZ228836A (de) |
| PT (1) | PT90328B (de) |
| ZA (1) | ZA892920B (de) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUT65753A (en) * | 1991-04-04 | 1994-07-28 | Procter & Gamble | Chewable antacid compositions and process for production of them |
| FR2677546B1 (fr) * | 1991-06-12 | 1994-01-21 | Fabienne Joanny | Composition therapeutique pour liberation prolonge de magnesium. |
| GB9310412D0 (en) * | 1993-05-20 | 1993-07-07 | Danbiosyst Uk | Nasal nicotine system |
| US5622980A (en) * | 1993-08-17 | 1997-04-22 | Applied Analytical Industries, Inc. | Oral compositions of H2-antagonists |
| DE4415999A1 (de) * | 1994-05-06 | 1995-11-09 | Bolder Arzneimittel Gmbh | Magensäurebindende Kaupastillen |
| EP0761227A4 (de) * | 1994-06-06 | 1998-06-10 | Yamanouchi Pharma Co Ltd | Festes antazidum und verfahren für seine herstellung |
| US6306828B1 (en) * | 1995-04-06 | 2001-10-23 | Baxter International, Inc. | Enantiomerically-enhanced nutritional energy substrates |
| WO1997019699A1 (en) * | 1995-11-27 | 1997-06-05 | Yamanouchi Pharmaceutical Co., Ltd. | Drug composition |
| US6699885B2 (en) * | 1996-01-04 | 2004-03-02 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and methods of using same |
| US5840737A (en) | 1996-01-04 | 1998-11-24 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
| US6489346B1 (en) * | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
| US6645988B2 (en) * | 1996-01-04 | 2003-11-11 | Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
| SE9600071D0 (sv) | 1996-01-08 | 1996-01-08 | Astra Ab | New oral formulation of two active ingredients I |
| US6174548B1 (en) | 1998-08-28 | 2001-01-16 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
| US6096340A (en) * | 1997-11-14 | 2000-08-01 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
| US6733778B1 (en) * | 1999-08-27 | 2004-05-11 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
| FR2793688B1 (fr) * | 1999-05-21 | 2003-06-13 | Ethypharm Lab Prod Ethiques | Microgranules gastroproteges, procede d'obtention et preparations pharmaceutiques |
| CN1252154C (zh) | 1999-07-22 | 2006-04-19 | 沃纳-兰伯特公司 | 支链淀粉膜组合物 |
| US6780880B1 (en) | 1999-08-26 | 2004-08-24 | Robert R. Whittle | FT-Raman spectroscopic measurement |
| US6262085B1 (en) | 1999-08-26 | 2001-07-17 | Robert R. Whittle | Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
| US6268385B1 (en) | 1999-08-26 | 2001-07-31 | Robert R. Whittle | Dry blend pharmaceutical formulations |
| US6316020B1 (en) | 1999-08-26 | 2001-11-13 | Robert R. Whittle | Pharmaceutical formulations |
| US6312712B1 (en) | 1999-08-26 | 2001-11-06 | Robert R. Whittle | Method of improving bioavailability |
| US6312723B1 (en) | 1999-08-26 | 2001-11-06 | Robert R. Whittle | Pharmaceutical unit dosage form |
| US6262086B1 (en) | 1999-08-26 | 2001-07-17 | Robert R. Whittle | Pharmaceutical unit dosage form |
| US6369087B1 (en) | 1999-08-26 | 2002-04-09 | Robert R. Whittle | Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
| US6326384B1 (en) | 1999-08-26 | 2001-12-04 | Robert R. Whittle | Dry blend pharmaceutical unit dosage form |
| EP1245227A1 (de) * | 2001-03-31 | 2002-10-02 | Jagotec Ag | Pharmazeutische, im Magen aufschwimmende Tablette für die programmierte Freisetzung des Wirkstoffes und Verfahren zur Herstellung des in der Tablette enthaltenen schwimmfähigen Materials |
| SE0101379D0 (sv) | 2001-04-18 | 2001-04-18 | Diabact Ab | Komposition som hämmar utsöndring av magsyra |
| US20040006111A1 (en) * | 2002-01-25 | 2004-01-08 | Kenneth Widder | Transmucosal delivery of proton pump inhibitors |
| SE0203065D0 (sv) | 2002-10-16 | 2002-10-16 | Diabact Ab | Gastric acid secretion inhibiting composition |
| WO2004073654A2 (en) * | 2003-02-20 | 2004-09-02 | Santarus, Inc. | A novel formulation, omeprazole antacid complex-immediate release for rapid and sustained supression of gastric acid |
| US20050220870A1 (en) * | 2003-02-20 | 2005-10-06 | Bonnie Hepburn | Novel formulation, omeprazole antacid complex-immediate release for rapid and sustained suppression of gastric acid |
| US8993599B2 (en) * | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
| JP2006528181A (ja) * | 2003-07-18 | 2006-12-14 | サンタラス インコーポレイティッド | 酸分泌を阻害するために有用な薬学的製剤ならびにそれらを作製および使用する方法 |
| MXPA06000524A (es) * | 2003-07-18 | 2006-08-11 | Santarus Inc | Formulacion farmaceutica y metodo para tratar desordenes gastrointestinales provocados por acido. |
| US20070292498A1 (en) * | 2003-11-05 | 2007-12-20 | Warren Hall | Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers |
| US8906940B2 (en) * | 2004-05-25 | 2014-12-09 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
| US8815916B2 (en) * | 2004-05-25 | 2014-08-26 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
| JP2006131581A (ja) * | 2004-11-09 | 2006-05-25 | Kyowa Chem Ind Co Ltd | 崩壊剤及びこれを含有する崩壊性成形物 |
| EP2026768B1 (de) * | 2006-06-01 | 2018-02-28 | Dexcel Pharma Technologies Ltd. | Pharmazeutische formulierung auf mehreren einheiten |
| US20090092658A1 (en) * | 2007-10-05 | 2009-04-09 | Santarus, Inc. | Novel formulations of proton pump inhibitors and methods of using these formulations |
| EP2719376B1 (de) | 2012-10-12 | 2015-03-04 | Omya International AG | Gastroretentive Arzneimittelformulierung und Verabreichungssysteme und ihre Herstellungsverfahren unter Verwendung von funktionalisiertem Calciumcarbonat |
| EP3034070A1 (de) | 2014-12-18 | 2016-06-22 | Omya International AG | Verfahren zur Herstellung eines pharmazeutischen Abgabesystems |
| EP3069713A1 (de) | 2015-03-20 | 2016-09-21 | Omya International AG | Dispergierbare dosierungsform |
| EP3288556A4 (de) | 2015-04-29 | 2018-09-19 | Dexcel Pharma Technologies Ltd. | Oral zerfallende zusammensetzungen |
| CA2898600A1 (en) * | 2015-07-28 | 2017-01-28 | Jayson King | Stuffing box containment apparatus |
| US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
| EP3269361A1 (de) | 2016-07-14 | 2018-01-17 | Omya International AG | Darreichungsform |
| CN110327370B (zh) * | 2019-04-16 | 2021-02-23 | 马德君 | 阴离子黏土用于制备驱铅药物的用途 |
| CN110780063A (zh) * | 2019-12-10 | 2020-02-11 | 无锡市尚沃医疗电子股份有限公司 | 一种呼气氨检测方法和装置 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1416304A (fr) * | 1961-10-10 | 1965-11-05 | Smith Kline French Lab | Perfectionnements apportés aux tablettes et comprimés renfermant une importante quantité d'ingrédient actif libéré pendant un laps de temps prolongé, et aux procédés pour leur préparation |
| CA948107A (en) * | 1970-04-28 | 1974-05-28 | Robert S. Joslin | Coated antacid compositions of improved taste |
| US4101650A (en) * | 1977-04-06 | 1978-07-18 | Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai | Pepstatin floating minicapsules |
| HU179474B (en) * | 1978-02-24 | 1982-10-28 | Laszlo Gyarmati | Process for preparing solid oral pharmaceutical compositons with increased length of activity and with a regulated release of the active material |
| MTP930B (en) * | 1982-04-30 | 1984-04-10 | Delandale Labs Ltd | Substained release lithium-containing tablets and method for their manufacture |
| US4605551A (en) * | 1984-11-30 | 1986-08-12 | William H. Rorer, Inc. | Dry oil coated antacid process |
| US4778676A (en) * | 1985-12-20 | 1988-10-18 | Warner-Lambert Company | Confectionery delivery system for actives |
| JPS62195323A (ja) * | 1986-02-24 | 1987-08-28 | Eisai Co Ltd | 胃内滞留型粒子 |
| US4921707A (en) * | 1986-06-24 | 1990-05-01 | Istvan Racz | Proceeding for the production of pharmaceutical preparations of high gastric acid binding capacity, of retarded effect and of increased bioavailability |
-
1988
- 1988-04-21 GB GB888809421A patent/GB8809421D0/en active Pending
-
1989
- 1989-04-19 AU AU33175/89A patent/AU616257B2/en not_active Ceased
- 1989-04-19 DK DK188489A patent/DK188489A/da not_active Application Discontinuation
- 1989-04-20 US US07/340,780 patent/US5288506A/en not_active Expired - Fee Related
- 1989-04-20 ZA ZA892920A patent/ZA892920B/xx unknown
- 1989-04-20 NZ NZ228836A patent/NZ228836A/xx unknown
- 1989-04-20 PT PT90328A patent/PT90328B/pt not_active IP Right Cessation
- 1989-04-20 KR KR1019890005207A patent/KR950007205B1/ko not_active Expired - Fee Related
- 1989-04-20 FI FI891896A patent/FI98886C/fi not_active IP Right Cessation
- 1989-04-20 NO NO891641A patent/NO176868C/no unknown
- 1989-04-20 IE IE128289A patent/IE61866B1/en not_active IP Right Cessation
- 1989-04-21 EP EP89304013A patent/EP0338861B1/de not_active Expired - Lifetime
- 1989-04-21 AT AT89304013T patent/ATE84708T1/de not_active IP Right Cessation
- 1989-04-21 ES ES89304013T patent/ES2044099T3/es not_active Expired - Lifetime
- 1989-04-21 JP JP1100327A patent/JPH0764724B2/ja not_active Expired - Lifetime
- 1989-04-21 CA CA000597383A patent/CA1336495C/en not_active Expired - Fee Related
- 1989-04-21 DE DE8989304013T patent/DE68904459T2/de not_active Expired - Fee Related
-
1993
- 1993-01-28 GR GR930400155T patent/GR3006908T3/el unknown
-
1995
- 1995-06-30 HU HU95P/P00697P patent/HU211236A9/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GR3006908T3 (de) | 1993-06-30 |
| NO176868C (no) | 1995-06-14 |
| EP0338861A3 (en) | 1990-09-19 |
| AU616257B2 (en) | 1991-10-24 |
| HU211236A9 (en) | 1995-11-28 |
| DK188489D0 (da) | 1989-04-19 |
| KR890015733A (ko) | 1989-11-25 |
| KR950007205B1 (ko) | 1995-07-04 |
| FI891896A0 (fi) | 1989-04-20 |
| DK188489A (da) | 1989-10-23 |
| FI98886B (fi) | 1997-05-30 |
| IE891282L (en) | 1989-10-21 |
| PT90328B (pt) | 1994-11-30 |
| ES2044099T3 (es) | 1994-01-01 |
| ZA892920B (en) | 1989-12-27 |
| CA1336495C (en) | 1995-08-01 |
| NO891641D0 (no) | 1989-04-20 |
| JPH0215025A (ja) | 1990-01-18 |
| DE68904459T2 (de) | 1993-05-13 |
| NO176868B (no) | 1995-03-06 |
| IE61866B1 (en) | 1994-11-30 |
| AU3317589A (en) | 1989-10-26 |
| PT90328A (pt) | 1989-11-10 |
| NO891641L (no) | 1989-10-23 |
| US5288506A (en) | 1994-02-22 |
| NZ228836A (en) | 1990-09-26 |
| GB8809421D0 (en) | 1988-05-25 |
| FI891896L (fi) | 1989-10-22 |
| EP0338861A2 (de) | 1989-10-25 |
| EP0338861B1 (de) | 1993-01-20 |
| JPH0764724B2 (ja) | 1995-07-12 |
| FI98886C (fi) | 1997-09-10 |
| DE68904459D1 (de) | 1993-03-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EEIH | Change in the person of patent owner | ||
| REN | Ceased due to non-payment of the annual fee |