ITMI912212A1 - Composizioni farmaceutiche solide per somministrazione orale aventi proungata residenza gastrica - Google Patents

Composizioni farmaceutiche solide per somministrazione orale aventi proungata residenza gastrica

Info

Publication number
ITMI912212A1
ITMI912212A1 IT002212A ITMI912212A ITMI912212A1 IT MI912212 A1 ITMI912212 A1 IT MI912212A1 IT 002212 A IT002212 A IT 002212A IT MI912212 A ITMI912212 A IT MI912212A IT MI912212 A1 ITMI912212 A1 IT MI912212A1
Authority
IT
Italy
Prior art keywords
oral administration
pharmaceutical compositions
solid pharmaceutical
prohibited
gastric residence
Prior art date
Application number
IT002212A
Other languages
English (en)
Inventor
Fabio Cari
Pierandrea Esposito
Original Assignee
Vectorpharma Internat S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vectorpharma Internat S P A filed Critical Vectorpharma Internat S P A
Priority to ITMI912212A priority Critical patent/IT1251153B/it
Publication of ITMI912212A0 publication Critical patent/ITMI912212A0/it
Priority to ES92113187T priority patent/ES2086029T3/es
Priority to AT92113187T priority patent/ATE134134T1/de
Priority to DE69208299T priority patent/DE69208299T2/de
Priority to EP92113187A priority patent/EP0526862B1/en
Publication of ITMI912212A1 publication Critical patent/ITMI912212A1/it
Application granted granted Critical
Publication of IT1251153B publication Critical patent/IT1251153B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ITMI912212A 1991-08-06 1991-08-06 Composizioni farmaceutiche solide per somministrazione orale aventi proungata residenza gastrica IT1251153B (it)

Priority Applications (5)

Application Number Priority Date Filing Date Title
ITMI912212A IT1251153B (it) 1991-08-06 1991-08-06 Composizioni farmaceutiche solide per somministrazione orale aventi proungata residenza gastrica
ES92113187T ES2086029T3 (es) 1991-08-06 1992-08-03 Composiciones farmaceuticas solidas para la administracion oral con permanencia gastrica prolongada.
AT92113187T ATE134134T1 (de) 1991-08-06 1992-08-03 Feste arzneizubereitungen zur oralen verabreichung mit verlängerter magenverweilzeit
DE69208299T DE69208299T2 (de) 1991-08-06 1992-08-03 Feste Arzneizubereitungen zur oralen Verabreichung mit verlängerter Magenverweilzeit
EP92113187A EP0526862B1 (en) 1991-08-06 1992-08-03 Solid pharmaceutical compositions for oral administration with prolonged gastric residence

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI912212A IT1251153B (it) 1991-08-06 1991-08-06 Composizioni farmaceutiche solide per somministrazione orale aventi proungata residenza gastrica

Publications (3)

Publication Number Publication Date
ITMI912212A0 ITMI912212A0 (it) 1991-08-06
ITMI912212A1 true ITMI912212A1 (it) 1993-02-07
IT1251153B IT1251153B (it) 1995-05-04

Family

ID=11360543

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI912212A IT1251153B (it) 1991-08-06 1991-08-06 Composizioni farmaceutiche solide per somministrazione orale aventi proungata residenza gastrica

Country Status (5)

Country Link
EP (1) EP0526862B1 (it)
AT (1) ATE134134T1 (it)
DE (1) DE69208299T2 (it)
ES (1) ES2086029T3 (it)
IT (1) IT1251153B (it)

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JP3332426B2 (ja) * 1992-10-02 2002-10-07 太田製薬株式会社 大腸および小腸の検査用ｘ線造影剤
WO1994020074A1 (en) * 1993-03-12 1994-09-15 The Procter & Gamble Company Adsorbate compositions
FR2703250A1 (fr) * 1993-03-30 1994-10-07 Chicouri Marcel Nouvelles compositions pharmaceutiques à base de bismuth et leur procédé de préparation.
US6284727B1 (en) 1993-04-07 2001-09-04 Scios, Inc. Prolonged delivery of peptides
IL109460A (en) 1993-05-10 1998-03-10 Euro Celtique Sa Controlled release formulation comprising tramadol
IT1265074B1 (it) * 1993-05-18 1996-10-30 Istituto Biochimico Italiano Composizione farmaceutica a lento rilascio contenente come sostanza attiva un acido biliare
US5455046A (en) * 1993-09-09 1995-10-03 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems for insoluble drugs
KR100354702B1 (ko) 1993-11-23 2002-12-28 유로-셀티크 소시에떼 아노뉨 약학조성물의제조방법및서방형조성물
US5891471A (en) 1993-11-23 1999-04-06 Euro-Celtique, S.A. Pharmaceutical multiparticulates
DE4404011A1 (de) * 1994-02-09 1995-08-10 Jenapharm Gmbh Neue, adhäsiv wirkende Zubereitungen für mit Flüssigkeit benetzte Oberflächen, Verfahren und Vorrichtung zur Erfassung der Adhäsionszeit diesbezüglicher Zubereitungen
US5843480A (en) 1994-03-14 1998-12-01 Euro-Celtique, S.A. Controlled release diamorphine formulation
GB9422154D0 (en) 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
US5965161A (en) 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
CH687810A5 (de) * 1995-05-24 1997-02-28 Mepha Ag Pelletformulierung mit Omeprazol.
AU6378796A (en) * 1995-06-06 1996-12-24 Warner-Lambert Company Ranitidine salts on magnesium trisilicate as an adsorbate
ES2112765B1 (es) * 1995-08-02 1999-03-01 Cantabria Ind Farmaceutica Sa Procedimiento para la obtencion de formulaciones de constraste radiologico, para exploraciones gastrointestinales de uso extemporaneo y directo.
DE19533162A1 (de) * 1995-09-08 1997-03-13 Bayer Ag Pharmazeutisches Kombinationspräparat mit Ketoprofen
SE9600071D0 (sv) 1996-01-08 1996-01-08 Astra Ab New oral formulation of two active ingredients I
US5985312A (en) * 1996-01-26 1999-11-16 Brown University Research Foundation Methods and compositions for enhancing the bioadhesive properties of polymers
US6368586B1 (en) 1996-01-26 2002-04-09 Brown University Research Foundation Methods and compositions for enhancing the bioadhesive properties of polymers
GB9607955D0 (en) * 1996-04-17 1996-06-19 Tillotts Pharma Ag Hydrophobic carbomer salt compositions
EP0843559A2 (en) * 1996-06-11 1998-05-27 Zonagen, Inc. Chitosan drug delivery system
AU5446798A (en) * 1996-11-27 1998-06-22 Procter & Gamble Company, The Compositions and methods for the treatment of gastrointestinal disorders
GB2329334A (en) * 1997-09-18 1999-03-24 Reckitt & Colmann Prod Ltd Cholesterol-lowering agents
SE9704869D0 (sv) 1997-12-22 1997-12-22 Astra Ab New pharmaceutical formulaton II
HUP0102260A3 (en) * 1998-06-05 2002-12-28 Warner Lambert Co Stabilization of compositions containing ace inhibitors using magnesium oxide
DE69930648T2 (de) 1998-08-12 2006-12-21 Altana Pharma Ag Orale darreichungsform für pyridin-2-ylmethylsulfinyl-1h-benzimidazole
US6319513B1 (en) 1998-08-24 2001-11-20 The Procter & Gamble Company Oral liquid mucoadhesive compounds
ATE424810T1 (de) * 1998-12-11 2009-03-15 Nostrum Pharmaceuticals Inc Ein hydrokolloid und einen celluloseether enthaltende tablette mit verzögerter freisetzung
DE19918325A1 (de) 1999-04-22 2000-10-26 Euro Celtique Sa Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
AU1169601A (en) * 1999-11-16 2001-05-30 Ranbaxy Laboratories Limited Taste masked oral compositions
PT1251832E (pt) 2000-02-04 2007-01-31 Depomed Inc Forma de dosagem constituída por invólucro-e-núcleo que conduz a uma libertação do fármaco de ordem zero
US6248360B1 (en) 2000-06-21 2001-06-19 International Health Management Associates, Inc. Complexes to improve oral absorption of poorly absorbable antibiotics
US7527807B2 (en) 2000-06-21 2009-05-05 Cubist Pharmaceuticals, Inc. Compositions and methods for increasing the oral absorption of antimicrobials
MXPA02012670A (es) * 2000-06-21 2003-10-06 Cubist Pharm Inc Composiciones y metodos para mejorar la absorcion oral de agentes anti-microbianos.
GB2373438A (en) * 2001-02-10 2002-09-25 Reckitt & Colmann Prod Ltd Cholesterol lowering compositions
MXPA03008293A (es) 2001-03-13 2003-12-11 Penwest Pharmaceuticals Co Formas de dosis cronoterapeuticas.
US20030158254A1 (en) * 2002-01-24 2003-08-21 Xenoport, Inc. Engineering absorption of therapeutic compounds via colonic transporters
KR100782918B1 (ko) 2003-09-19 2007-12-07 펜웨스트 파머슈티칼즈 컴파니 지연 방출성 제형
MXPA06003101A (es) 2003-09-19 2006-06-20 Penwest Pharmaceuticals Co Formas de dosis cronoterapeuticas.
TWI372066B (en) 2003-10-01 2012-09-11 Wyeth Corp Pantoprazole multiparticulate formulations
DE102004023069A1 (de) 2004-05-11 2005-12-08 Bayer Healthcare Ag Neue Darreichungsformen des PDE 5-Inhibitors Vardenafil
US8968781B2 (en) 2005-04-29 2015-03-03 Cubist Pharmaceuticals, Inc. Therapeutic compositions
CN101516353B (zh) * 2006-08-30 2013-10-16 雅戈泰克股份公司 包含核心和一个或多个阻挡层的控释口服制剂
AU2013202344B2 (en) * 2006-08-30 2014-07-17 Jagotec Ag Controlled release oral dosage formulations comprising a core and one or more barrier layers
EP2063871A1 (en) 2006-08-30 2009-06-03 Jagotec AG Controlled release solid oral dosage formulations comprising nisoldipine

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DE3431861A1 (de) * 1984-08-30 1986-03-13 Troponwerke GmbH & Co KG, 5000 Köln Pellet-zubereitung
ATE71293T1 (de) * 1986-09-18 1992-01-15 London Pharmacy Innovation Arzneiformulierung.

Also Published As

Publication number Publication date
DE69208299T2 (de) 1996-07-18
ATE134134T1 (de) 1996-02-15
EP0526862A1 (en) 1993-02-10
DE69208299D1 (de) 1996-03-28
ITMI912212A0 (it) 1991-08-06
ES2086029T3 (es) 1996-06-16
IT1251153B (it) 1995-05-04
EP0526862B1 (en) 1996-02-14

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960830