ATE79749T1 - Verwendung von einigen alkanoyl-l-carnitinen zur herstellung eines arzneimittels zur therapeutischen behandlung von ideopathischem oder induziertem parkinsonismus. - Google Patents
Verwendung von einigen alkanoyl-l-carnitinen zur herstellung eines arzneimittels zur therapeutischen behandlung von ideopathischem oder induziertem parkinsonismus.Info
- Publication number
- ATE79749T1 ATE79749T1 AT86830150T AT86830150T ATE79749T1 AT E79749 T1 ATE79749 T1 AT E79749T1 AT 86830150 T AT86830150 T AT 86830150T AT 86830150 T AT86830150 T AT 86830150T AT E79749 T1 ATE79749 T1 AT E79749T1
- Authority
- AT
- Austria
- Prior art keywords
- carnitines
- alkanoyl
- ideopathic
- medication
- manufacture
- Prior art date
Links
- 208000027089 Parkinsonian disease Diseases 0.000 title abstract 2
- 206010034010 Parkinsonism Diseases 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- -1 alkanoyl L-carnitines Chemical class 0.000 abstract 2
- RDHQFKQIGNGIED-MRVPVSSYSA-N O-acetyl-L-carnitine Chemical compound CC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C RDHQFKQIGNGIED-MRVPVSSYSA-N 0.000 abstract 1
- 208000018737 Parkinson disease Diseases 0.000 abstract 1
- 239000002117 illicit drug Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT48206/85A IT1181682B (it) | 1985-06-11 | 1985-06-11 | Impiego di alcanoil l-carnitine per il trattamento terapeutico del parkinsonismo idiopatico o indotto |
| EP86830150A EP0207011B1 (de) | 1985-06-11 | 1986-06-03 | Verwendung von einigen Alkanoyl-L-carnitinen zur Herstellung eines Arzneimittels zur therapeutischen Behandlung von ideopathischem oder induziertem Parkinsonismus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE79749T1 true ATE79749T1 (de) | 1992-09-15 |
Family
ID=11265224
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT86830150T ATE79749T1 (de) | 1985-06-11 | 1986-06-03 | Verwendung von einigen alkanoyl-l-carnitinen zur herstellung eines arzneimittels zur therapeutischen behandlung von ideopathischem oder induziertem parkinsonismus. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4663352A (de) |
| EP (1) | EP0207011B1 (de) |
| JP (1) | JPH0684298B2 (de) |
| AT (1) | ATE79749T1 (de) |
| DE (1) | DE3686520T2 (de) |
| IT (1) | IT1181682B (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1208753B (it) * | 1986-07-02 | 1989-07-10 | Sigma Tau Ind Farmaceuti | L-amminoacil derivati della l-carnitina, procedimento per la loro preparazione e composizioni farmaceutiche ad attivita' epatoprotettrice che li contengono |
| IT1224842B (it) * | 1988-12-27 | 1990-10-24 | Sigma Tau Ind Farmaceuti | Uso di derivati della l-carnitina nel trattamento terapeutico delle alterazioni degenerative del sistema nervoso |
| US5641764A (en) * | 1989-03-31 | 1997-06-24 | Peter Maccallum Institute | Halogenated DNA ligand radiosensitizers for cancer therapy |
| IT1245699B (it) * | 1991-05-29 | 1994-10-14 | Sigma Tau Ind Farmaceuti | Derivati della l-carnitina quali agenti terapeutici per il trattamento delle miopatie, della degenarazione neuronale e per inibire la proteolisi |
| IT1263004B (it) * | 1992-10-08 | 1996-07-23 | Sigma Tau Ind Farmaceuti | Impiego della l-carnitina e acil l-carnitine nel trattamento a lungo termine di pazienti diabetici non insulino-dipendenti. |
| IT1284661B1 (it) * | 1996-06-06 | 1998-05-21 | Sigma Tau Ind Farmaceuti | Uso di alcanoil l-carnitine nel trattamento terapeutico di malattie infiammatorie croniche intestinali. |
| IT1305308B1 (it) * | 1999-03-26 | 2001-05-04 | Biosint S P A | Granulato ad alto contenuto di l-carnitina o alcanoil-l-carnitina,particolarmente adatto alla produzione di compresse per compressione |
| US20050232911A1 (en) * | 2004-04-19 | 2005-10-20 | Schreiber Brian D | Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid |
| US20060252775A1 (en) * | 2005-05-03 | 2006-11-09 | Henderson Samuel T | Methods for reducing levels of disease associated proteins |
| EP3115034B1 (de) | 2008-05-30 | 2020-05-06 | KCI Licensing, Inc. | Lineare wundverschlusspolster mit reduziertem druck und entsprechende systeme |
| JP5406283B2 (ja) | 2008-05-30 | 2014-02-05 | ケーシーアイ ライセンシング インコーポレイテッド | 湾曲した身体部分に用いる減圧・圧縮システムおよび装置 |
| EP2586438A1 (de) | 2011-10-28 | 2013-05-01 | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. | Verbindung zur Verwendung bei der Vorbeugung von kognitiven Mangelerscheinungen bei einem Neugeborenen von einer HIV-serumpositiven Mutter, die mit Azidothymidin |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4346107A (en) * | 1979-02-12 | 1982-08-24 | Claudio Cavazza | Pharmaceutical composition comprising acyl-carnitine for the treatment of impaired cerebral metabolism |
| IT1206954B (it) * | 1979-02-12 | 1989-05-17 | Sigma Tau Ind Farmaceuti | Agenti terapeutici a base di un acil derivato della carnitina per la cura di vasculopatie periferiche |
| IT1150396B (it) * | 1982-12-09 | 1986-12-10 | Sigma Tau Ind Farmaceuti | Impiego di alcanoil l-carnitine per il trattamento terapeutico di miopa tie e distrofie muscolari |
| US4537772A (en) * | 1984-05-02 | 1985-08-27 | Merck & Co., Inc. | Enhancing absorption of drugs from gastrointestinal tract using acylcarnitines |
-
1985
- 1985-06-11 IT IT48206/85A patent/IT1181682B/it active
-
1986
- 1986-05-30 US US06/869,083 patent/US4663352A/en not_active Expired - Lifetime
- 1986-06-03 DE DE8686830150T patent/DE3686520T2/de not_active Expired - Fee Related
- 1986-06-03 AT AT86830150T patent/ATE79749T1/de not_active IP Right Cessation
- 1986-06-03 EP EP86830150A patent/EP0207011B1/de not_active Expired - Lifetime
- 1986-06-10 JP JP61135868A patent/JPH0684298B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE3686520D1 (de) | 1992-10-01 |
| IT8548206A0 (it) | 1985-06-11 |
| EP0207011B1 (de) | 1992-08-26 |
| US4663352A (en) | 1987-05-05 |
| EP0207011A3 (en) | 1989-11-29 |
| EP0207011A2 (de) | 1986-12-30 |
| IT1181682B (it) | 1987-09-30 |
| JPH0684298B2 (ja) | 1994-10-26 |
| JPS61286326A (ja) | 1986-12-16 |
| DE3686520T2 (de) | 1993-02-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee |