|
US4932871A
(en)
*
|
1987-11-20 |
1990-06-12 |
Miles Inc. |
Rapid method for preparing chromogenic alpha-amylase substrate compounds at high preparative yields
|
|
US5104980A
(en)
*
|
1989-06-12 |
1992-04-14 |
Miles Inc. |
Chromogenic dibenzoxazepinone and dibenzothiazepinone enzyme substrates
|
|
US5183743A
(en)
*
|
1989-06-12 |
1993-02-02 |
Miles Inc. |
Chromogenic dibenzoxazepinone and dibenzothiazepinone enzyme substrates
|
|
AU7176091A
(en)
*
|
1989-12-29 |
1991-07-24 |
Symex Corp. |
Chromogenic 7- or 8-position modified n-acetylneuraminic acid substrates and methods for diagnosing human influenza therewith
|
|
US5663055A
(en)
*
|
1989-12-29 |
1997-09-02 |
Oklahoma Medical Research Foundation |
Methods for diagnosing human influenza and 4-position modified chromogenic N-acetylneuraminic acid substrated for use therein
|
|
DE69131504T2
(de)
*
|
1990-12-31 |
1999-11-18 |
Oklahoma Medical Research Foundation, Oklahoma |
Verfahren zum visuellen nachweis der anwesenheit eines virus in einer klinischen probe
|
|
US5252458A
(en)
*
|
1990-12-31 |
1993-10-12 |
Symex Corp. |
Method for visually detecting the presence of a virus in a clinical specimen
|
|
USRE38723E1
(en)
*
|
1991-08-23 |
2005-04-12 |
Molecular Probes, Inc. |
Haloalkyl derivatives of reporter molecules used to analyze metabolic activity in cells
|
|
US5576424A
(en)
*
|
1991-08-23 |
1996-11-19 |
Molecular Probes, Inc. |
Haloalkyl derivatives of reporter molecules used to analyze metabolic activity in cells
|
|
US5208326A
(en)
*
|
1991-11-08 |
1993-05-04 |
Miles Inc. |
8-hydroxy-2h-dibenz(b,f)azepin-2-one dyes
|
|
US5264577A
(en)
*
|
1992-04-22 |
1993-11-23 |
Warner-Lambert Company |
Cyclic amino acids and derivatives thereof
|
|
JPH07509245A
(ja)
*
|
1992-07-20 |
1995-10-12 |
デイド・ベーリング・マルブルク・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング |
新規化学発光化合物およびその使用方法
|
|
US6002000A
(en)
*
|
1992-07-20 |
1999-12-14 |
Dade Behring Marburg Gmbh |
Chemiluminescent compounds and methods of use
|
|
US5393615A
(en)
*
|
1994-02-03 |
1995-02-28 |
Miles Inc. |
Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof
|
|
US5567624A
(en)
*
|
1995-04-27 |
1996-10-22 |
Utah Medical Products, Inc. |
Carbazine dyes and derivatives for pH measurement
|
|
JP3169383B2
(ja)
*
|
1996-01-16 |
2001-05-21 |
ルミゲン インク |
ホスファターゼ酵素で化学発光を生成させるための化合物、組成物および方法
|
|
US5719020A
(en)
*
|
1996-09-25 |
1998-02-17 |
Oklahoma Medical Research Foundation |
4,7-dialkoxy N-acetylneuraminic acid derivatives and methods for detection of influenza type A and B viruses in clinical specimens
|
|
US5773236A
(en)
*
|
1997-04-25 |
1998-06-30 |
Molecule Probes, Inc. |
Assay for glutathiane transferase using polyhaloaryl-substituted reporter molecules
|
|
US6303764B1
(en)
|
1998-09-24 |
2001-10-16 |
Zymetx, Inc. |
Synthesis of 4,7-dialkyl chromogenic glycosides of N-acetylneuraminic acids
|
|
US6420130B1
(en)
|
1998-12-14 |
2002-07-16 |
Aurora Biosciences Corporation |
Optical molecular sensors for cytochrome P450 activity
|
|
DE69907962T2
(de)
*
|
1998-12-14 |
2004-05-19 |
Vertex Pharmaceuticals (San Diego) Llc, San Diego |
Optische molekularsensoren für cytochrome p-450 aktivität
|
|
DE60001531T2
(de)
|
1999-04-23 |
2003-10-02 |
Molecular Probes, Inc. |
Xanthenfarbstoffe und ihre anwendung als lumineszenzlöschende verbindungen
|
|
US6783948B1
(en)
*
|
1999-07-30 |
2004-08-31 |
Bayer Corporation |
Chemiluminescent acridinium compounds and analogues thereof as substrates of hydrolytic enzymes
|
|
ATE291096T1
(de)
*
|
1999-07-30 |
2005-04-15 |
Bayer Ag |
Chemilumineszenz-substrate von hydrolytischen enzymen wie phosphatasen
|
|
US6420552B1
(en)
|
1999-09-10 |
2002-07-16 |
Zymetx, Inc. |
Syntheses of 4-alkyl chromogenic glycosides and 7-alkyl chromogenic glycosides of N-acetylneuraminic acids
|
|
US6323337B1
(en)
|
2000-05-12 |
2001-11-27 |
Molecular Probes, Inc. |
Quenching oligonucleotides
|
|
US6448422B1
(en)
|
2000-07-03 |
2002-09-10 |
Eli Lilly And Company |
Chromogenic compound
|
|
US7579463B2
(en)
|
2000-12-20 |
2009-08-25 |
Life Technologies Corporation |
Crown ether derivatives
|
|
US6962992B2
(en)
|
2000-12-20 |
2005-11-08 |
Molecullar Probes, Inc. |
Crown ether derivatives
|
|
US7622446B2
(en)
*
|
2001-04-18 |
2009-11-24 |
The Open University |
Polypeptides, derivatives and uses thereof
|
|
US7491702B2
(en)
|
2001-04-18 |
2009-02-17 |
The Open University |
Polypeptides related to amyloid precursor protein, pharmaceutical compositions thereof, and methods of treatment using the same
|
|
US8323903B2
(en)
*
|
2001-10-12 |
2012-12-04 |
Life Technologies Corporation |
Antibody complexes and methods for immunolabeling
|
|
US20050069962A1
(en)
*
|
2001-10-12 |
2005-03-31 |
Archer Robert M |
Antibody complexes and methods for immunolabeling
|
|
US6972326B2
(en)
*
|
2001-12-03 |
2005-12-06 |
Molecular Probes, Inc. |
Labeling of immobilized proteins using dipyrrometheneboron difluoride dyes
|
|
US7186696B2
(en)
*
|
2002-03-07 |
2007-03-06 |
Toyama University |
Reagent and method for measuring amylase
|
|
US7183069B2
(en)
*
|
2002-03-07 |
2007-02-27 |
Toyama University |
Reagent, method and apparatus for measuring amylase activity
|
|
US20040171034A1
(en)
*
|
2002-05-03 |
2004-09-02 |
Brian Agnew |
Compositions and methods for detection and isolation of phosphorylated molecules
|
|
US7445894B2
(en)
*
|
2002-05-03 |
2008-11-04 |
Molecular Probes, Inc. |
Compositions and methods for detection and isolation of phosphorylated molecules
|
|
CA2483868A1
(en)
*
|
2002-05-03 |
2004-05-21 |
Molecular Probes, Inc. |
Compositions and methods for detection and isolation of phosphorylated molecules
|
|
US20050233307A1
(en)
*
|
2002-09-12 |
2005-10-20 |
Kyle Gee |
Site-specific labeling of affinity tags in fusion proteins
|
|
US20040101822A1
(en)
|
2002-11-26 |
2004-05-27 |
Ulrich Wiesner |
Fluorescent silica-based nanoparticles
|
|
FR2850378B1
(fr)
*
|
2003-01-29 |
2005-03-04 |
Bio Merieux |
Substrats enzymatiques, milieux de culture les contenant, utilisation pour detecter une activite aminopeptidase et/ou differencier des bacteries a gram+ par rapport a des bacteries a gram-
|
|
US7429472B2
(en)
|
2003-01-31 |
2008-09-30 |
Promega Corporation |
Method of immobilizing a protein or molecule via a mutant dehalogenase that is bound to an immobilized dehalogenase substrate and linked directly or indirectly to the protein or molecule
|
|
EP1594962B1
(de)
|
2003-01-31 |
2014-08-27 |
Promega Corporation |
Kovalentes anbinden funktioneller gruppen an proteine
|
|
US8445702B2
(en)
*
|
2003-05-05 |
2013-05-21 |
Life Technologies Corporation |
Zinc binding compounds and their method of use
|
|
US20050250214A1
(en)
*
|
2004-05-05 |
2005-11-10 |
Gee Kyle R |
Zinc binding compounds and their method of use
|
|
CA2445420A1
(en)
*
|
2003-07-29 |
2005-01-29 |
Invitrogen Corporation |
Kinase and phosphatase assays
|
|
US7619059B2
(en)
*
|
2003-07-29 |
2009-11-17 |
Life Technologies Corporation |
Bimolecular optical probes
|
|
US7727752B2
(en)
*
|
2003-07-29 |
2010-06-01 |
Life Technologies Corporation |
Kinase and phosphatase assays
|
|
US7271265B2
(en)
*
|
2003-08-11 |
2007-09-18 |
Invitrogen Corporation |
Cyanine compounds and their application as quenching compounds
|
|
JP2007505315A
(ja)
*
|
2003-09-12 |
2007-03-08 |
インヴィトロジェン コーポレーション |
多重結合および活性アッセイ
|
|
US7282339B2
(en)
*
|
2003-09-17 |
2007-10-16 |
Invitrogen Corporation |
Competitive immunoassay
|
|
US20050214807A1
(en)
*
|
2003-11-19 |
2005-09-29 |
Iain Johnson |
Environmental sensitive fluorogenic compounds and their application for singlet oxygen and protein detection
|
|
US7776529B2
(en)
|
2003-12-05 |
2010-08-17 |
Life Technologies Corporation |
Methine-substituted cyanine dye compounds
|
|
US7446202B2
(en)
|
2003-12-05 |
2008-11-04 |
Molecular Probes, Inc. |
Cyanine dye compounds
|
|
WO2005065241A2
(en)
*
|
2003-12-24 |
2005-07-21 |
Argose, Inc. |
Smmr (small molecule metabolite reporters) for use as in vivo glucose biosensors
|
|
US20050227309A1
(en)
|
2004-01-21 |
2005-10-13 |
Corry Schuyler B |
Optically-detectable enzyme substrates and their method of use
|
|
US20060024833A1
(en)
|
2004-07-27 |
2006-02-02 |
Molecular Probes, Inc. |
Fluorescent metal ion indicators with large stokes shift
|
|
EP2395358B1
(de)
|
2004-07-30 |
2017-03-29 |
Promega Corporation |
Kovalentes Anbinden von Funktionsgruppen an Proteine
|
|
CN101258220A
(zh)
|
2004-09-16 |
2008-09-03 |
阿普里拉股份有限公司 |
荧光染料化合物,共轭物及其应用
|
|
US8084001B2
(en)
*
|
2005-05-02 |
2011-12-27 |
Cornell Research Foundation, Inc. |
Photoluminescent silica-based sensors and methods of use
|
|
JP5306811B2
(ja)
|
2005-05-11 |
2013-10-02 |
ライフ テクノロジーズ コーポレーション |
2本鎖dnaへの高い選択性を有する蛍光化学物質及びそれらの使用
|
|
US20070134685A1
(en)
*
|
2005-09-06 |
2007-06-14 |
Invitrogen Corporation |
Control of chemical modification
|
|
ES2434491T3
(es)
*
|
2005-10-13 |
2013-12-16 |
Funda��O D. Anna Sommer Champalimaud E Dr. Carlos Montez Champalimaud |
An�lisis inmunohistoqu�mico multiplex in situ
|
|
US7521577B2
(en)
*
|
2006-01-12 |
2009-04-21 |
Molecular Probes, Inc. |
Heavy metal binding compounds and their method of use
|
|
USD580285S1
(en)
|
2006-01-13 |
2008-11-11 |
Invitrogen Corporation |
Fluorometer
|
|
US20070196860A1
(en)
*
|
2006-01-18 |
2007-08-23 |
Invitrogen Corporation |
Methods for Measuring Real Time Kinase Activity
|
|
WO2007087582A1
(en)
|
2006-01-24 |
2007-08-02 |
Invitrogen Corporation |
Device and methods for quantifying analytes
|
|
EP2623986B1
(de)
|
2006-02-10 |
2017-06-14 |
Life Technologies Corporation |
Markierung und Detektion von posttranslational modifizierten Proteinen
|
|
US8114636B2
(en)
|
2006-02-10 |
2012-02-14 |
Life Technologies Corporation |
Labeling and detection of nucleic acids
|
|
US8562802B1
(en)
|
2006-02-13 |
2013-10-22 |
Life Technologies Corporation |
Transilluminator base and scanner for imaging fluorescent gels, charging devices and portable electrophoresis systems
|
|
ES2371039T3
(es)
|
2006-03-23 |
2011-12-26 |
Absorber Ab |
Antígenos de grupo sanguíneo de diferentes tipos para aplicaciones diagnósticas y terapéuticas.
|
|
AU2007240316A1
(en)
|
2006-04-20 |
2007-11-01 |
Becton, Dickinson And Company |
Thermostable proteins and methods of making and using thereof
|
|
WO2008076524A2
(en)
|
2006-10-27 |
2008-06-26 |
Life Technologies Corporation |
Fluorogenic ph sensitive dyes and their method of use
|
|
EP2374875B1
(de)
|
2006-10-30 |
2015-09-02 |
Promega Corporation |
Mutante Hydrolaseproteine mit verstärkten kinetischen Eigenschaften und funktioneller Expression
|
|
US8586743B2
(en)
*
|
2007-01-30 |
2013-11-19 |
Life Technologies Corporation |
Labeling reagents and methods of their use
|
|
WO2008151089A2
(en)
*
|
2007-05-30 |
2008-12-11 |
Invitrogen Corporation |
Fluorescent phospholipase a2 indicators
|
|
US20090247984A1
(en)
*
|
2007-10-24 |
2009-10-01 |
Masimo Laboratories, Inc. |
Use of microneedles for small molecule metabolite reporter delivery
|
|
US10996218B2
(en)
|
2008-03-11 |
2021-05-04 |
Ournextbaby Llc |
Methods for chemotaxis / redox driven separation of X and Y chromosome bearing sperm and their insemination in gender specific menstrual cycles
|
|
JP5774471B2
(ja)
|
2008-03-27 |
2015-09-09 |
プロメガ コーポレイションPromega Corporation |
シアノベンゾチアゾールコンジュゲートによるタンパク質標識
|
|
CN104263816B
(zh)
*
|
2008-05-16 |
2018-10-19 |
生命技术公司 |
用于测量细胞增殖的双标记法
|
|
US20110171124A1
(en)
|
2009-02-26 |
2011-07-14 |
Osi Pharmaceuticals, Inc. |
In situ methods for monitoring the EMT status of tumor cells in vivo
|
|
WO2010135834A1
(en)
*
|
2009-05-29 |
2010-12-02 |
Mcmaster University |
Biosensors utilizing ink jet-printed biomolecule compatible sol gel inks and uses thereof
|
|
WO2010141359A2
(en)
*
|
2009-06-01 |
2010-12-09 |
Bayer Healthcare Llc |
Redox molecules and methods of making the same
|
|
WO2011003109A1
(en)
|
2009-07-02 |
2011-01-06 |
Sloan-Kettering Institute For Cancer Research |
Fluorescent silica-based nanoparticles
|
|
US12161734B2
(en)
|
2009-07-02 |
2024-12-10 |
Sloan-Kettering Institute For Cancer Research |
Multimodal silica-based nanoparticles
|
|
GB0915664D0
(en)
|
2009-09-08 |
2009-10-07 |
Enigma Diagnostics Ltd |
Reaction method
|
|
WO2011054731A1
(en)
|
2009-11-05 |
2011-05-12 |
Basf Se |
Fluorescent materials
|
|
US8974651B2
(en)
|
2010-04-17 |
2015-03-10 |
C.C. Imex |
Illuminator for visualization of fluorophores
|
|
WO2011150155A1
(en)
|
2010-05-28 |
2011-12-01 |
Bayer Healthcare Llc |
Polymer bonded redox molecules and methods of making the same
|
|
USD653981S1
(en)
|
2010-08-06 |
2012-02-14 |
Life Technologies Corporation |
Fluorometer
|
|
WO2012022734A2
(en)
|
2010-08-16 |
2012-02-23 |
Medimmune Limited |
Anti-icam-1 antibodies and methods of use
|
|
EP2619573B1
(de)
|
2010-09-16 |
2017-06-14 |
Urobiologics LLC |
Verwendung des harns von weiblichen säugetieren zur bestimmung von fetalen geschlechtsspezifischen merkmalen
|
|
CN107326073A
(zh)
|
2010-12-29 |
2017-11-07 |
生命技术公司 |
作为荧光参考标准品的 ddao 化合物
|
|
AU2013259519B2
(en)
*
|
2012-05-08 |
2017-07-13 |
Rutgers, The State University Of New Jersey |
Methods to detect a fungal cell
|
|
US20150246146A1
(en)
|
2012-10-25 |
2015-09-03 |
Life Technologies Corporation |
Methods and compositions for enzyme-mediated site-specific radiolabeling of glycoproteins
|
|
JP6604938B2
(ja)
|
2013-03-15 |
2019-11-13 |
プロメガ コーポレイション |
タンパク質を官能基または固体表面に共有結合的に係留するための基質
|
|
WO2015050959A1
(en)
|
2013-10-01 |
2015-04-09 |
Yale University |
Anti-kit antibodies and methods of use thereof
|
|
EP3733244A1
(de)
|
2013-10-02 |
2020-11-04 |
Medlmmune, LLC |
Neutralisierende antiinflueanza-a-virus-antikörper und verwendungen davon
|
|
US10542918B2
(en)
|
2013-10-23 |
2020-01-28 |
Verily Life Sciences Llc |
Modulation of a response signal to distinguish between analyte and background signals
|
|
US9636034B2
(en)
|
2013-10-23 |
2017-05-02 |
Verily Life Sciences Llc |
Non-invasive analyte detection system with modulation source
|
|
US9835587B2
(en)
|
2014-04-01 |
2017-12-05 |
C.C. Imex |
Electrophoresis running tank assembly
|
|
CN113082225A
(zh)
|
2014-05-29 |
2021-07-09 |
纪念斯隆-凯特琳癌症中心 |
纳米粒子药物结合物
|
|
EP3242690B1
(de)
|
2015-01-06 |
2020-09-16 |
De Haas, Anthony H. |
Chirurgische nahinfrarot-fluoreszenzfarbstoffmarker
|
|
US9861710B1
(en)
|
2015-01-16 |
2018-01-09 |
Verily Life Sciences Llc |
Composite particles, methods, and in vivo diagnostic system
|
|
US10028659B2
(en)
|
2015-03-26 |
2018-07-24 |
Verily Life Sciences Llc |
Aptamer-based sensors, implantable devices and detection system
|
|
JP6974178B2
(ja)
|
2015-05-29 |
2021-12-01 |
メモリアル スローン ケタリング キャンサー センター |
フェロトーシスを介して栄養欠乏がん細胞の細胞死を誘導するための極小ナノ粒子を使用する処置方法
|
|
EP3304078B1
(de)
|
2015-06-05 |
2022-08-31 |
Promega Corporation |
Zelldurchlässige, zellkompatible und spaltbare linker zur kovalenten bindung von funktionselementen
|
|
JP6967006B2
(ja)
|
2016-01-15 |
2021-11-17 |
クアンタポール, インコーポレイテッド |
低減されたバックグラウンドの光学に基づくナノポア分析
|
|
WO2017181176A1
(en)
|
2016-04-15 |
2017-10-19 |
Lcahn School Of Medicine At Mount Sinai |
Tissue profiling using multiplexed immunohistochemical consecutive staining
|
|
BR112018073378A2
(pt)
|
2016-05-20 |
2019-03-06 |
Quantum-Si Incorporated |
composições de nucleotídeos marcados e métodos para sequenciamento de ácidos nucleicos
|
|
AU2017312746A1
(en)
|
2016-08-19 |
2019-01-31 |
Quantapore, Inc. |
Optically-based nanopore sequencing using quenching agents
|
|
CN110546273A
(zh)
|
2017-03-30 |
2019-12-06 |
生命技术公司 |
通过衔接子序列定量ngs dna
|
|
CA3064253A1
(en)
|
2017-05-25 |
2018-11-29 |
Memorial Sloan Kettering Cancer Center |
Ultrasmall nanoparticles labeled with zirconium-89 and methods thereof
|
|
US11442063B2
(en)
|
2018-05-30 |
2022-09-13 |
Promega Corporation |
Broad spectrum kinase binding agents
|
|
EP3891503A2
(de)
|
2018-12-04 |
2021-10-13 |
Promega Corporation |
Cpcr-binder mit breitem spektrum
|
|
US20210363565A1
(en)
|
2020-05-22 |
2021-11-25 |
Promega Corporation |
Enhancement of kinase target engagement
|
|
KR20230034333A
(ko)
|
2020-07-02 |
2023-03-09 |
라이프 테크놀로지스 코포레이션 |
트리뉴클레오티드 캡 유사체, 제조 및 이의 용도
|
|
EP4204808A1
(de)
|
2020-08-28 |
2023-07-05 |
Promega Corporation |
Zielbindungsassay für ras-proteine
|
|
US20250092261A1
(en)
|
2021-07-21 |
2025-03-20 |
Life Technologies Corporation |
Dibenzoxanthene Quenchers, Uses, and Methods of Preparation
|