ATE7300T1 - Alkylierte verbindungen von c-076-verbindungen, verfahren zu deren herstellung und deren verwendung als antiparasitische mittel. - Google Patents

Alkylierte verbindungen von c-076-verbindungen, verfahren zu deren herstellung und deren verwendung als antiparasitische mittel.

Info

Publication number
ATE7300T1
ATE7300T1 AT79301515T AT79301515T ATE7300T1 AT E7300 T1 ATE7300 T1 AT E7300T1 AT 79301515 T AT79301515 T AT 79301515T AT 79301515 T AT79301515 T AT 79301515T AT E7300 T1 ATE7300 T1 AT E7300T1
Authority
AT
Austria
Prior art keywords
carbon atoms
hydrocarbon
substituted
compounds
alkyl
Prior art date
Application number
AT79301515T
Other languages
English (en)
Inventor
Michael Herbert Fisher
Aino Lusi
Richard Lee Tolman
Original Assignee
Merck & Co. Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co. Inc. filed Critical Merck & Co. Inc.
Application granted granted Critical
Publication of ATE7300T1 publication Critical patent/ATE7300T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
AT79301515T 1978-08-04 1979-07-30 Alkylierte verbindungen von c-076-verbindungen, verfahren zu deren herstellung und deren verwendung als antiparasitische mittel. ATE7300T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/930,845 US4200581A (en) 1978-08-04 1978-08-04 Alkyl derivatives of C-076 compounds
EP79301515A EP0008184B1 (de) 1978-08-04 1979-07-30 Alkylierte Verbindungen von C-076-Verbindungen, Verfahren zu deren Herstellung und deren Verwendung als antiparasitische Mittel

Publications (1)

Publication Number Publication Date
ATE7300T1 true ATE7300T1 (de) 1984-05-15

Family

ID=25459864

Family Applications (1)

Application Number Title Priority Date Filing Date
AT79301515T ATE7300T1 (de) 1978-08-04 1979-07-30 Alkylierte verbindungen von c-076-verbindungen, verfahren zu deren herstellung und deren verwendung als antiparasitische mittel.

Country Status (10)

Country Link
US (1) US4200581A (de)
EP (1) EP0008184B1 (de)
JP (1) JPS5524165A (de)
AT (1) ATE7300T1 (de)
AU (1) AU526571B2 (de)
DE (1) DE2966954D1 (de)
DK (1) DK328579A (de)
IE (1) IE48913B1 (de)
NZ (1) NZ191088A (de)
ZA (1) ZA793993B (de)

Families Citing this family (50)

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JPS5296011A (en) * 1976-02-06 1977-08-12 Nippon Telegr & Teleph Corp <Ntt> Production of magnetic head
JPS52130316A (en) * 1976-04-26 1977-11-01 Nippon Telegr & Teleph Corp <Ntt> Production of magnetic heads
US4289760A (en) * 1980-05-02 1981-09-15 Merck & Co., Inc. 23-Keto derivatives of C-076 compounds
US4389397A (en) * 1980-08-04 1983-06-21 Merck & Co., Inc. Solubilization of ivermectin in water
US4285963A (en) * 1980-08-07 1981-08-25 Merck & Co., Inc. Novel derivatives of C-076 compounds
US4378353A (en) * 1981-02-17 1983-03-29 Merck & Co., Inc. Novel C-076 compounds
US4333925A (en) * 1981-05-11 1982-06-08 Merck & Co., Inc. Derivatives of C-076 compounds
US4399274A (en) * 1981-07-02 1983-08-16 Merck & Co., Inc. Isolation of non-ionic lipophilic materials on macroreticular polymeric absorbents
US4408059A (en) * 1981-12-04 1983-10-04 University Patents, Inc. Spiroketals useful as intermediates in the synthesis of milbemycin and avermectin macrolides
US4427663A (en) * 1982-03-16 1984-01-24 Merck & Co., Inc. 4"-Keto-and 4"-amino-4"-deoxy avermectin compounds and substituted amino derivatives thereof
US4469682A (en) * 1983-01-28 1984-09-04 Merck & Co., Inc. Avermectin and milbemycin phosphate esters, pharmaceutical compositions, and method of use
US5106994A (en) * 1984-06-05 1992-04-21 American Cyanamid Company Agents and method of production thereof
US5317030A (en) * 1984-06-05 1994-05-31 American Cyanamid Company Method and compositions for helmintic, arthropod ectoparasitic and acaridal infections with novel agents
US5198464A (en) * 1984-06-05 1993-03-30 American Cyanamid Company Method and compositions for helmintic, arthropod ectoparasitic and acaridal infections with novel agents
US5169956A (en) * 1984-06-05 1992-12-08 American Cyanamid Company Macrolide antibiotic compounds
US4547491A (en) * 1984-07-18 1985-10-15 Merck & Co., Inc. C-8A-Oxo-avermectin and milbemycin derivatives, pharmaceutical compositions and method of use
AT396250B (de) * 1984-09-14 1993-07-26 American Cyanamid Co Verfahren zur herstellung von neuen antibiotisch wirkenden verbindungen
HUT39739A (en) * 1984-12-04 1986-10-29 Ciba Geigy Ag Process for production of derivatives of 13,3-milbemycin and medical preparatives containing thereof
GB2168345B (en) * 1984-12-14 1988-05-25 Ciba Geigy Ag Pesticidal 13b-substituted milbemycin derivatives
US4587247A (en) * 1985-02-25 1986-05-06 Merck & Co., Inc. Substituted and unsubstituted 13-(alkoxy)methoxy derivatives of the avermectin aglycones, compositions and use
ES8800986A1 (es) * 1985-07-27 1987-12-01 Pfizer Un procedimiento para la produccion de un nuevo derivado de avermectina
JPH0678342B2 (ja) * 1986-01-07 1994-10-05 三共株式会社 新規マクロライド化合物
EP0239528A1 (de) * 1986-03-05 1987-09-30 Ciba-Geigy Ag 13Beta-Carbamoyloxy-milbemycinderivate zur Bekämpfung von tier- und pflanzenparasitären Schädlingen
RU2024527C1 (ru) * 1986-03-25 1994-12-15 Санкио Компани Лимитед Способ получения макролидных соединений
EP0245209A1 (de) * 1986-05-07 1987-11-11 Ciba-Geigy Ag Milbemycin-Derivate, ihre Herstellung und ihre Verwendung zur Bekämpfung von Schädlingen
ES2039258T3 (es) * 1986-07-02 1993-09-16 Ciba-Geigy Ag Pesticidas.
US5840704A (en) * 1986-07-16 1998-11-24 Pfizer Inc. Antiparasitic agents and process for their preparation
US4897416A (en) * 1987-02-18 1990-01-30 Ciba-Geigy Corporation Insecticides and parasiticides
ES2045146T3 (es) * 1987-11-09 1994-01-16 Pfizer Avermectinas etiladas.
GB8726730D0 (en) * 1987-11-14 1987-12-16 Pfizer Ltd Antiparasitic agents
US4895837A (en) * 1988-01-29 1990-01-23 Merck & Co., Inc. Avermectin derivatives
GB8804440D0 (en) * 1988-02-25 1988-03-23 Pfizer Ltd Antiparasitic agents
US4918097A (en) * 1988-03-11 1990-04-17 Ciba-Geigy Corporation Insecticides and parasiticides
US5428034A (en) * 1988-09-02 1995-06-27 Sankyo Co., Ltd. Milbemycin derivatives, their preparation and their use
NZ232422A (en) * 1989-02-16 1992-11-25 Merck & Co Inc 13-ketal milbemycin derivatives and parasiticides
JP2622197B2 (ja) * 1990-03-01 1997-06-18 三共株式会社 １３−エーテル置換ミルベマイシン誘導体
US5188944A (en) * 1990-06-22 1993-02-23 Merck & Co., Inc. Process for the glycosylation of avermectin agylcones
US5171742A (en) * 1991-10-15 1992-12-15 Merck & Co., Inc. Avermectin compounds with a 6,5-spiroketal ring system ad a 23-acyl substituent
US5240915A (en) * 1991-10-15 1993-08-31 Merck & Co., Inc. Avermectin derivatives
GB9201505D0 (en) * 1992-01-24 1992-03-11 Pfizer Ltd Antiparasitic agents
US5162363A (en) * 1992-03-18 1992-11-10 Merck & Co., Inc. 23-nor-23-thia avermectin analogs are active anthelmintic agents
US5229415A (en) * 1992-03-24 1993-07-20 Merck & Co., Inc. Alkylthio alkyl avermectins are active antiparasitic agents
US6103504A (en) * 1992-03-25 2000-08-15 Pfizer Inc. Process for production of avermectins and cultures therefor
DE69310539T2 (de) * 1992-11-20 1998-01-15 British Tech Group Bildrekonstruktion
AU5261301A (en) 2000-04-27 2001-11-12 Sankyo Co 13-substituted milbemycin derivatives, their preparation and their use against insects and other pests
WO2002012261A1 (fr) * 2000-08-09 2002-02-14 The Kitasato Institute Dérivés d'avermectine
AU2001278694A1 (en) * 2000-08-09 2002-02-18 The Kitasato Institute Avermectin derivatives
US7001889B2 (en) * 2002-06-21 2006-02-21 Merial Limited Anthelmintic oral homogeneous veterinary pastes
US20060205681A1 (en) * 2002-06-21 2006-09-14 Maryam Moaddeb Homogenous paste formulations
US20080027011A1 (en) * 2005-12-20 2008-01-31 Hassan Nached Homogeneous paste and gel formulations

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2173778A1 (en) * 1972-03-02 1973-10-12 Aries Robert 5-phenoxyalkyltetrazoles - hypocholesterolaemics and anorectics
US3950360A (en) * 1972-06-08 1976-04-13 Sankyo Company Limited Antibiotic substances
SE434277B (sv) * 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
NZ186851A (en) * 1977-04-11 1984-12-14 Merck & Co Inc Glycosyloxy derivatives of milbemycin and parasiticidal compositions
US4093629A (en) * 1977-04-11 1978-06-06 Merck & Co., Inc. Derivatives of antibiotic substance milbemycin and processes therefor
NZ188459A (en) * 1977-10-03 1982-09-07 Merck & Co Inc Derivatives of c-076 compounds and pesticidal compositions
PH15982A (en) * 1977-10-03 1983-05-18 Merck & Co Inc Selective hydrogenation producta of c-076 compounds and derivatives thereof
JPS6254113A (ja) * 1985-09-03 1987-03-09 Fuji Electric Co Ltd 管内スケ−ル厚さの測定方法

Also Published As

Publication number Publication date
EP0008184A1 (de) 1980-02-20
NZ191088A (en) 1984-09-28
IE48913B1 (en) 1985-06-12
US4200581A (en) 1980-04-29
ZA793993B (en) 1981-03-25
DE2966954D1 (en) 1984-06-07
DK328579A (da) 1980-02-05
EP0008184B1 (de) 1984-05-02
IE791437L (en) 1980-02-04
AU526571B2 (en) 1983-01-20
JPH0238596B2 (de) 1990-08-31
JPS5524165A (en) 1980-02-21
AU4923379A (en) 1980-02-07

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Legal Events

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