ATE67491T1 - Benzopyran-derivate. - Google Patents

Benzopyran-derivate.

Info

Publication number
ATE67491T1
ATE67491T1 AT87108047T AT87108047T ATE67491T1 AT E67491 T1 ATE67491 T1 AT E67491T1 AT 87108047 T AT87108047 T AT 87108047T AT 87108047 T AT87108047 T AT 87108047T AT E67491 T1 ATE67491 T1 AT E67491T1
Authority
AT
Austria
Prior art keywords
group
hydrogen atom
bond
substituted
lower alkyl
Prior art date
Application number
AT87108047T
Other languages
English (en)
Inventor
Masayuki Kitagawa
Makoto Tanaka
Original Assignee
Daiichi Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co
Application granted granted Critical
Publication of ATE67491T1 publication Critical patent/ATE67491T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/34—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only
    • C07D311/36—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only not hydrogenated in the hetero ring, e.g. isoflavones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/34—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only
    • C07D311/38—2,3-Dihydro derivatives, e.g. isoflavanones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT87108047T 1986-06-04 1987-06-03 Benzopyran-derivate. ATE67491T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP12942086 1986-06-04
EP87108047A EP0248420B1 (de) 1986-06-04 1987-06-03 Benzopyran-Derivate

Publications (1)

Publication Number Publication Date
ATE67491T1 true ATE67491T1 (de) 1991-10-15

Family

ID=15009071

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87108047T ATE67491T1 (de) 1986-06-04 1987-06-03 Benzopyran-derivate.

Country Status (17)

Country Link
US (1) US4841076A (de)
EP (1) EP0248420B1 (de)
JP (1) JPH0681750B2 (de)
KR (1) KR930009793B1 (de)
CN (1) CN1020100C (de)
AT (1) ATE67491T1 (de)
AU (1) AU611083B2 (de)
CA (1) CA1319694C (de)
DE (1) DE3773053D1 (de)
DK (1) DK164862C (de)
ES (1) ES2044867T3 (de)
GR (1) GR3003372T3 (de)
IE (1) IE60203B1 (de)
NZ (1) NZ220540A (de)
PH (1) PH24882A (de)
YU (1) YU46209B (de)
ZA (1) ZA873745B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4889871A (en) * 1987-05-29 1989-12-26 G. D. Searle & Co. Alkoxy-substituted dihydrobenzopyran-2-carboxylate derivatives
AU628331B2 (en) * 1988-05-06 1992-09-17 Merck Patent Gesellschaft Mit Beschrankter Haftung Chroman derivatives
GB8823980D0 (en) * 1988-10-13 1988-11-23 Glaxo Group Ltd Chemical compounds
US5703075A (en) * 1988-12-21 1997-12-30 Pharmacia & Upjohn Company Antiatherosclerotic and antithrombotic 1-benzopyran-4-ones and 2-amino-1,3-benzoxazine-4-ones
EP0459983A1 (de) * 1988-12-21 1991-12-11 PHARMACIA & UPJOHN COMPANY Antiatherosklerotische und antithrombotische 1-benzopyran-4-one und 2-amino-1,3-benzoxazin-4-one
JPH0366669A (ja) * 1989-08-03 1991-03-22 Shionogi & Co Ltd 複素環式化合物
EP0525123B1 (de) * 1990-06-20 1997-09-17 PHARMACIA & UPJOHN COMPANY Antiatherosklerotische und antithrombotische 1-benzopyran-4-on- und 2-amino-1,3-benzoxazin-4-on-derivate
US5204369A (en) * 1991-07-01 1993-04-20 The Endowment For Research In Human Biology Method for the inhibition of aldh-i useful in the treatment of alcohol dependence or alcohol abuse
FR2693724B1 (fr) * 1992-07-17 1994-10-07 Lipha Utilisation de composés benzopyraniques ou benzothiopyraniques pour l'induction de l'expression des gènes de la nodulation des bactéries du genre Rhizobium associées aux légumineuses.
DE69333611T2 (de) * 1992-12-21 2005-09-15 Mallinckrodt, Inc. Radiomarkierte mehrwertige phenolverbindungen
US5457124A (en) * 1993-12-07 1995-10-10 Hoffmann-La Roche Inc. Carboxylic acid Leukotriene B4 antagonists
AU4315996A (en) * 1994-12-28 1996-07-19 Dainippon Pharmaceutical Co. Ltd. Carboxylic acid derivatives, process for producing the same, and medicinal composition containing the same
PL187175B1 (pl) * 1995-10-13 2004-05-31 Bayer Cropscience Ltd Bicykliczne związki heterocykliczne, kompozycja grzybobójcza je zawierająca i ich zastosowanie
US6255497B1 (en) 1997-04-29 2001-07-03 The Endowment For Research In Human Biology, Inc. Method for the inhibition of ALDH-I useful in the treatment of alcohol dependence or alcohol abuse
HUP9902721A2 (hu) 1997-11-25 1999-12-28 The Procter & Gamble Co. Tömény textillágyító készítmény és ehhez alkalmazható magas telítetlenségű textillágyító vegyület
CN1358091A (zh) * 1999-04-16 2002-07-10 阿斯特拉曾尼卡有限公司 雌激素受体－β配体
GB0412769D0 (en) * 2004-06-08 2004-07-07 Novartis Ag Organic compounds
GB0412768D0 (en) * 2004-06-08 2004-07-07 Novartis Ag Organic compounds
KR100930467B1 (ko) 2007-06-07 2009-12-08 동아제약주식회사 점액분비를 촉진시키는 3',4',5-트리메톡시 플라본 유도체화합물, 그의 제조방법 및 약학적 용도
US8093253B2 (en) * 2008-03-06 2012-01-10 Hoffmann-La Roche Inc. Leukotriene B4 inhibitors
CN103044377B (zh) * 2013-01-08 2014-12-10 中国药科大学 具有抑制黄嘌呤氧化酶和降尿酸作用的化合物以及组合物
JP6178010B2 (ja) * 2013-08-27 2017-08-09 シノケム・コーポレーションＳｉｎｏｃｈｅｍ Ｃｏｒｐｏｒａｔｉｏｎ 抗腫瘍薬の製造のための置換ベンジルオキシ基含有エーテル化合物の適用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD24560A (de) *
GB803372A (en) * 1955-11-02 1958-10-22 Recordati Lab Farmacologico S Hydroxychromone derivatives and methods of preparing the same
DE1210882B (de) * 1961-07-14 1966-02-17 Cassella Farbwerke Mainkur Ag Verfahren zur Herstellung von Derivaten des 7-Oxychromons
DE1193511B (de) * 1961-03-16 1965-05-26 Cassella Farbwerke Mainkur Ag Verfahren zur Herstellung von Derivaten des 7-Oxychromons
BE666541A (de) * 1964-07-08
US3864362A (en) * 1970-05-27 1975-02-04 Chinoin Gyogyszer Es Vegyeszet Iso flavones
HU162377B (de) * 1970-05-27 1973-02-28
JPS4732074U (de) * 1971-04-28 1972-12-11
ES477270A1 (es) * 1979-01-30 1979-10-16 Farmasimes S A Metodo para la preparacion de derivados de isoflavonas.
US4644012A (en) * 1983-12-21 1987-02-17 Takeda Chemical Industries, Ltd. Treatment for osteoporosis
DE3505611A1 (de) * 1984-11-26 1986-05-28 Merck Patent Gmbh, 6100 Darmstadt Halogen-hydroxy-flavone
US4678787A (en) * 1985-01-30 1987-07-07 Warner-Lambert Company 4H-1-benzopyran-4-ones and their sulfur containing analogs

Also Published As

Publication number Publication date
US4841076A (en) 1989-06-20
AU7381587A (en) 1987-12-10
DK164862B (da) 1992-08-31
CA1319694C (en) 1993-06-29
JPH0681750B2 (ja) 1994-10-19
DE3773053D1 (de) 1991-10-24
DK281687A (da) 1987-12-05
NZ220540A (en) 1990-04-26
KR880000421A (ko) 1988-03-25
ZA873745B (en) 1988-10-26
DK164862C (da) 1993-01-18
PH24882A (en) 1990-12-26
YU101787A (en) 1988-10-31
ES2044867T3 (es) 1994-01-16
EP0248420B1 (de) 1991-09-18
CN1020100C (zh) 1993-03-17
KR930009793B1 (ko) 1993-10-11
EP0248420A3 (en) 1988-10-12
AU611083B2 (en) 1991-06-06
IE871462L (en) 1987-12-04
CN87104319A (zh) 1988-05-04
YU46209B (sh) 1993-05-28
IE60203B1 (en) 1994-06-15
EP0248420A2 (de) 1987-12-09
JPS63107971A (ja) 1988-05-12
DK281687D0 (da) 1987-06-02
GR3003372T3 (en) 1993-02-17

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