ATE65393T1 - Ibupropfen-kristallaggregate enthaltendes arzneimittel. - Google Patents
Ibupropfen-kristallaggregate enthaltendes arzneimittel.Info
- Publication number
- ATE65393T1 ATE65393T1 AT87301825T AT87301825T ATE65393T1 AT E65393 T1 ATE65393 T1 AT E65393T1 AT 87301825 T AT87301825 T AT 87301825T AT 87301825 T AT87301825 T AT 87301825T AT E65393 T1 ATE65393 T1 AT E65393T1
- Authority
- AT
- Austria
- Prior art keywords
- ibupropfen
- compaction
- product containing
- medicinal product
- ibuprofen
- Prior art date
Links
- 239000013078 crystal Substances 0.000 title abstract 2
- 229940126601 medicinal product Drugs 0.000 title 1
- HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 abstract 4
- 229960001680 ibuprofen Drugs 0.000 abstract 4
- 238000005056 compaction Methods 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 238000004090 dissolution Methods 0.000 abstract 1
- 238000001125 extrusion Methods 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 238000005469 granulation Methods 0.000 abstract 1
- 230000003179 granulation Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Organic Chemistry (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Polyurethanes Or Polyureas (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB868606762A GB8606762D0 (en) | 1986-03-19 | 1986-03-19 | Therapeutic agents |
| EP87301825A EP0241126B1 (en) | 1986-03-19 | 1987-03-03 | Pharmaceutical composition comprising aggregates of crystals of ibuprofen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE65393T1 true ATE65393T1 (de) | 1991-08-15 |
Family
ID=10594868
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87301825T ATE65393T1 (de) | 1986-03-19 | 1987-03-03 | Ibupropfen-kristallaggregate enthaltendes arzneimittel. |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0241126B1 (en, 2012) |
| JP (1) | JPS62230723A (en, 2012) |
| KR (1) | KR870008582A (en, 2012) |
| CN (1) | CN87101974A (en, 2012) |
| AT (1) | ATE65393T1 (en, 2012) |
| AU (1) | AU7017787A (en, 2012) |
| CS (1) | CS182787A2 (en, 2012) |
| DD (1) | DD263232A5 (en, 2012) |
| DE (1) | DE3771544D1 (en, 2012) |
| DK (1) | DK136487A (en, 2012) |
| FI (1) | FI871112L (en, 2012) |
| GB (2) | GB8606762D0 (en, 2012) |
| HU (1) | HU195422B (en, 2012) |
| IL (1) | IL81884A0 (en, 2012) |
| IN (1) | IN163939B (en, 2012) |
| NO (1) | NO871120L (en, 2012) |
| NZ (1) | NZ219560A (en, 2012) |
| PL (1) | PL264695A1 (en, 2012) |
| PT (1) | PT84526B (en, 2012) |
| YU (1) | YU47087A (en, 2012) |
| ZA (1) | ZA871836B (en, 2012) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3833448A1 (de) * | 1988-10-01 | 1990-04-12 | Hoechst Ag | Verfahren zur gewinnung von ibuprofen fuer die direkttablettierung |
| NZ234587A (en) * | 1989-08-04 | 1991-11-26 | Mcneil Ppc Inc | A chewable pharmaceutical tablet of compressed coated granules |
| CA2063141C (en) * | 1989-08-04 | 1997-03-04 | Edward J. Roche | Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets |
| US5191114A (en) * | 1991-10-09 | 1993-03-02 | Sage Pharmaceuticals, Inc. | Process for enhancing the flow characteristics of ibuprofen |
| US5605930A (en) * | 1991-10-21 | 1997-02-25 | The United States Of America As Represented By The Department Of Health And Human Services | Compositions and methods for treating and preventing pathologies including cancer |
| US5534262A (en) * | 1992-01-10 | 1996-07-09 | Dobrotvorsky; Anatoly E. | Pharmaceutical granulated composition and method for preparing same |
| IS1736B (is) * | 1993-10-01 | 1999-12-30 | Astra Ab | Aðferð og tæki sem stuðla að aukinni samloðun agna |
| RU2170082C2 (ru) * | 1993-10-01 | 2001-07-10 | Астра Актиеболаг | Способ обработки лекарственного средства, устройство для формирования лекарственного средства и лекарственное средство |
| TWI225402B (en) | 1996-03-13 | 2004-12-21 | Biochemie Gmbh | Auxiliary-free agglomerates |
| FR2804603B1 (fr) * | 2000-02-04 | 2004-01-23 | Rhodia Chimie Sa | Procede continu pour formuler sous forme de granules une ou plusieurs matieres actives pharmaceutiques |
| DE102005037630A1 (de) | 2005-08-09 | 2007-02-15 | Glatt Gmbh | Verfahren zur Herstellung von Teilchen aus pharmazeutischen Substanzen, Teilchen aus pharmazeutischen Substanzen sowie deren Verwendung |
| CN105050708A (zh) | 2012-11-14 | 2015-11-11 | 格雷斯公司 | 含有生物活性材料与无序无机氧化物的组合物 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4476248A (en) * | 1983-02-28 | 1984-10-09 | The Upjohn Company | Crystallization of ibuprofen |
| JPS60120616A (ja) * | 1983-12-05 | 1985-06-28 | Yaskawa Electric Mfg Co Ltd | プリセット型可逆カウンタ装置 |
| US4609675A (en) * | 1984-08-17 | 1986-09-02 | The Upjohn Company | Stable, high dose, high bulk density ibuprofen granulations for tablet and capsule manufacturing |
-
1986
- 1986-03-19 GB GB868606762A patent/GB8606762D0/en active Pending
-
1987
- 1987-03-03 GB GB8704987A patent/GB2187952B/en not_active Revoked
- 1987-03-03 DE DE8787301825T patent/DE3771544D1/de not_active Expired - Fee Related
- 1987-03-03 AT AT87301825T patent/ATE65393T1/de active
- 1987-03-03 EP EP87301825A patent/EP0241126B1/en not_active Expired - Lifetime
- 1987-03-10 NZ NZ219560A patent/NZ219560A/xx unknown
- 1987-03-12 IN IN174/MAS/87A patent/IN163939B/en unknown
- 1987-03-13 IL IL81884A patent/IL81884A0/xx unknown
- 1987-03-13 ZA ZA871836A patent/ZA871836B/xx unknown
- 1987-03-13 FI FI871112A patent/FI871112L/fi not_active IP Right Cessation
- 1987-03-17 DD DD87300859A patent/DD263232A5/de not_active IP Right Cessation
- 1987-03-17 DK DK136487A patent/DK136487A/da not_active Application Discontinuation
- 1987-03-18 CS CS871827A patent/CS182787A2/cs unknown
- 1987-03-18 HU HU871184A patent/HU195422B/hu not_active IP Right Cessation
- 1987-03-18 NO NO871120A patent/NO871120L/no unknown
- 1987-03-18 JP JP62063658A patent/JPS62230723A/ja active Pending
- 1987-03-18 KR KR870002431A patent/KR870008582A/ko not_active Withdrawn
- 1987-03-18 PL PL1987264695A patent/PL264695A1/xx unknown
- 1987-03-19 AU AU70177/87A patent/AU7017787A/en not_active Abandoned
- 1987-03-19 YU YU00470/87A patent/YU47087A/xx unknown
- 1987-03-19 PT PT84526A patent/PT84526B/pt not_active IP Right Cessation
- 1987-03-19 CN CN198787101974A patent/CN87101974A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IL81884A0 (en) | 1987-10-20 |
| PL264695A1 (en) | 1988-05-12 |
| HU195422B (en) | 1988-05-30 |
| AU7017787A (en) | 1987-09-24 |
| FI871112A7 (fi) | 1987-09-20 |
| NZ219560A (en) | 1989-05-29 |
| CN87101974A (zh) | 1987-10-21 |
| GB8704987D0 (en) | 1987-04-08 |
| IN163939B (en, 2012) | 1988-12-10 |
| YU47087A (en) | 1988-04-30 |
| DK136487A (da) | 1987-09-20 |
| KR870008582A (ko) | 1987-10-19 |
| NO871120D0 (no) | 1987-03-18 |
| CS182787A2 (en) | 1991-05-14 |
| HUT42939A (en) | 1987-09-28 |
| DK136487D0 (da) | 1987-03-17 |
| DD263232A5 (de) | 1988-12-28 |
| DE3771544D1 (de) | 1991-08-29 |
| GB2187952B (en) | 1990-05-09 |
| FI871112A0 (fi) | 1987-03-13 |
| GB8606762D0 (en) | 1986-04-23 |
| EP0241126B1 (en) | 1991-07-24 |
| GB2187952A (en) | 1987-09-23 |
| EP0241126A1 (en) | 1987-10-14 |
| PT84526B (pt) | 1989-11-10 |
| NO871120L (no) | 1987-09-21 |
| PT84526A (en) | 1987-04-01 |
| ZA871836B (en) | 1987-09-02 |
| FI871112L (fi) | 1987-09-20 |
| JPS62230723A (ja) | 1987-10-09 |
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