ATE5772T1 - Verfahren zur herstellung von 1-isopropylamino-3(4-(2-methoxy-ethyl)-phenoxy)-2-propanol. - Google Patents
Verfahren zur herstellung von 1-isopropylamino-3(4-(2-methoxy-ethyl)-phenoxy)-2-propanol.Info
- Publication number
- ATE5772T1 ATE5772T1 AT81200558T AT81200558T ATE5772T1 AT E5772 T1 ATE5772 T1 AT E5772T1 AT 81200558 T AT81200558 T AT 81200558T AT 81200558 T AT81200558 T AT 81200558T AT E5772 T1 ATE5772 T1 AT E5772T1
- Authority
- AT
- Austria
- Prior art keywords
- phenoxy
- methoxyethyl
- isopropylamino
- propanol
- preparation
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- IUBSYMUCCVWXPE-UHFFFAOYSA-N metoprolol Chemical compound COCCC1=CC=C(OCC(O)CNC(C)C)C=C1 IUBSYMUCCVWXPE-UHFFFAOYSA-N 0.000 title abstract 2
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- ATUOYWHBWRKTHZ-UHFFFAOYSA-N Propane Chemical compound CCC ATUOYWHBWRKTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 2
- HUXGFSJRCMJOAK-UHFFFAOYSA-N 1-(4-hydroxyphenyl)-2-methoxyethanone Chemical compound COCC(=O)C1=CC=C(O)C=C1 HUXGFSJRCMJOAK-UHFFFAOYSA-N 0.000 abstract 1
- KFZMGEQAYNKOFK-UHFFFAOYSA-N 2-propanol Substances CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 abstract 1
- PETGYPBYTINWKW-UHFFFAOYSA-N 4-(1-hydroxy-2-methoxyethyl)phenol Chemical compound COCC(O)C1=CC=C(O)C=C1 PETGYPBYTINWKW-UHFFFAOYSA-N 0.000 abstract 1
- BRLQWZUYTZBJKN-UHFFFAOYSA-N Epichlorohydrin Chemical compound ClCC1CO1 BRLQWZUYTZBJKN-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- JJWLVOIRVHMVIS-UHFFFAOYSA-N isopropylamine Chemical compound CC(C)N JJWLVOIRVHMVIS-UHFFFAOYSA-N 0.000 abstract 1
- 239000001294 propane Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
- C07C43/14—Unsaturated ethers
- C07C43/178—Unsaturated ethers containing hydroxy or O-metal groups
- C07C43/1782—Unsaturated ethers containing hydroxy or O-metal groups containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
- C07D303/26—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds having one or more free hydroxyl radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Catalysts (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI801680A FI59985C (fi) | 1980-05-26 | 1980-05-26 | Foerfarande foer framstaellning av terapeutiskt aktiv 1-isopropylamino-3-(4-(2-metoxietyl)fenoxi)-2-propanol samt dess syra-additionssalter |
| EP81200558A EP0041295B1 (de) | 1980-05-26 | 1981-05-22 | Verfahren zur Herstellung von 1-Isopropylamino-3-(4-(2-methoxy-ethyl)-phenoxy)-2-propanol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE5772T1 true ATE5772T1 (de) | 1984-01-15 |
Family
ID=8513506
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT81200558T ATE5772T1 (de) | 1980-05-26 | 1981-05-22 | Verfahren zur herstellung von 1-isopropylamino-3(4-(2-methoxy-ethyl)-phenoxy)-2-propanol. |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0041295B1 (de) |
| JP (1) | JPS5711947A (de) |
| AT (1) | ATE5772T1 (de) |
| DK (1) | DK153143C (de) |
| FI (1) | FI59985C (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4665094A (en) * | 1985-08-29 | 1987-05-12 | Merck & Co., Inc. | Oculoselective beta-blockers for treatment of elevated intraocular pressure |
| US4945182A (en) * | 1985-12-24 | 1990-07-31 | Merck & Co., Inc. | Oculoselective beta-blockers |
| CN102964258B (zh) * | 2012-12-11 | 2014-01-29 | 上海奥博生物医药技术有限公司 | 一种美托洛尔有关物质j的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE354851B (de) * | 1970-02-18 | 1973-03-26 | Haessle Ab | |
| FI59392C (fi) * | 1978-04-01 | 1982-02-02 | Farmos Oy | Foerfarande foer framstaellning av terapeutiskt aktiv 1-isopropylamino-3-(4-(2-metoxietyl)fenoxi)-2-propanol samt dess syraadditionssalter |
| NL7907207A (nl) * | 1979-09-27 | 1981-03-31 | Farmos Oy | Werkwijze voor het bereiden van therapeutisch actief propanolamine. |
-
1980
- 1980-05-26 FI FI801680A patent/FI59985C/fi not_active IP Right Cessation
-
1981
- 1981-05-22 EP EP81200558A patent/EP0041295B1/de not_active Expired
- 1981-05-22 AT AT81200558T patent/ATE5772T1/de active
- 1981-05-25 DK DK227981A patent/DK153143C/da not_active IP Right Cessation
- 1981-05-25 JP JP7994381A patent/JPS5711947A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| DK153143B (da) | 1988-06-20 |
| JPH027937B2 (de) | 1990-02-21 |
| DK153143C (da) | 1988-10-31 |
| JPS5711947A (en) | 1982-01-21 |
| EP0041295B1 (de) | 1984-01-04 |
| EP0041295A1 (de) | 1981-12-09 |
| DK227981A (da) | 1981-11-27 |
| FI59985C (fi) | 1982-01-08 |
| FI59985B (fi) | 1981-07-31 |
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