ATE548371T1 - Tricyclische verbindung und deren medizinische verwendung - Google Patents
Tricyclische verbindung und deren medizinische verwendungInfo
- Publication number
- ATE548371T1 ATE548371T1 AT07850267T AT07850267T ATE548371T1 AT E548371 T1 ATE548371 T1 AT E548371T1 AT 07850267 T AT07850267 T AT 07850267T AT 07850267 T AT07850267 T AT 07850267T AT E548371 T1 ATE548371 T1 AT E548371T1
- Authority
- AT
- Austria
- Prior art keywords
- substituent
- optionally
- ring
- hydrocarbon group
- group optionally
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 10
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- YJPIGAIKUZMOQA-UHFFFAOYSA-N Melatonin Natural products COC1=CC=C2N(C(C)=O)C=C(CCN)C2=C1 YJPIGAIKUZMOQA-UHFFFAOYSA-N 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- DRLFMBDRBRZALE-UHFFFAOYSA-N melatonin Chemical compound COC1=CC=C2NC=C(CCNC(C)=O)C2=C1 DRLFMBDRBRZALE-UHFFFAOYSA-N 0.000 abstract 1
- 229960003987 melatonin Drugs 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- PXQLVRUNWNTZOS-UHFFFAOYSA-N sulfanyl Chemical class [SH] PXQLVRUNWNTZOS-UHFFFAOYSA-N 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
- C07D491/147—Ortho-condensed systems the condensed system containing one ring with oxygen as ring hetero atom and two rings with nitrogen as ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4355—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006332647 | 2006-12-08 | ||
| PCT/JP2007/073680 WO2008069311A1 (ja) | 2006-12-08 | 2007-12-07 | 三環性化合物およびその医薬用途 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE548371T1 true ATE548371T1 (de) | 2012-03-15 |
Family
ID=39492186
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07850267T ATE548371T1 (de) | 2006-12-08 | 2007-12-07 | Tricyclische verbindung und deren medizinische verwendung |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8273761B2 (de) |
| EP (1) | EP2100895B1 (de) |
| JP (1) | JP5227806B2 (de) |
| KR (1) | KR20090086641A (de) |
| CN (1) | CN101605795A (de) |
| AT (1) | ATE548371T1 (de) |
| AU (1) | AU2007329879A1 (de) |
| BR (1) | BRPI0719869A2 (de) |
| CA (1) | CA2671354A1 (de) |
| EA (1) | EA200970555A1 (de) |
| MX (1) | MX2009006078A (de) |
| WO (1) | WO2008069311A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2007342806A1 (en) | 2006-12-28 | 2008-07-17 | Takeda Pharmaceutical Company Limited | Tricyclic compound and pharmaceutical use thereof |
| JPWO2014010603A1 (ja) | 2012-07-10 | 2016-06-23 | アステラス製薬株式会社 | 腹圧性尿失禁又は混合型尿失禁の治療又は予防用医薬組成物、及び該医薬組成物に含有される化合物のスクリーニング方法 |
| AR091699A1 (es) * | 2012-07-10 | 2015-02-25 | Astellas Pharma Inc | Derivado de indol carboxamida |
| WO2016201265A1 (en) * | 2015-06-12 | 2016-12-15 | Mayo Foundation For Medical Education And Research | Mumps virus as a potential oncolytic agent |
| WO2017119455A1 (ja) | 2016-01-08 | 2017-07-13 | 武田薬品工業株式会社 | 自閉症スペクトラム障害の予防または治療剤 |
| CA3010727C (en) | 2016-01-08 | 2023-10-31 | Takeda Pharmaceutical Company Limited | Prophylactic or therapeutic agent for delirium |
| BR112020018286A2 (pt) | 2018-03-09 | 2020-12-29 | Recurium Ip Holdings, Llc | 1,2-di-hidro-3h-pirazolo[3,4-d]pirimidin-3-onas substituídas |
| AU2025210214A1 (en) | 2024-01-17 | 2026-07-30 | Rivo Bio, Inc. | Indane-, indene-, azaindane-, and azaindene-amines as activators of serotonin receptors |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9326192D0 (en) | 1993-12-22 | 1994-02-23 | Glaxo Group Ltd | Chemical compounds |
| FR2725985B1 (fr) | 1994-10-21 | 1996-11-15 | Adir | Nouveaux composes tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| US5998461A (en) | 1994-10-21 | 1999-12-07 | Adir Et Compagnie | Tricyclic amide compounds |
| FR2732969B1 (fr) * | 1995-04-14 | 1997-05-16 | Adir | Nouveaux composes pyridiniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| US6034239A (en) | 1996-03-08 | 2000-03-07 | Takeda Chemical Industries, Ltd. | Tricyclic compounds, their production and use |
| WO1997032871A1 (en) | 1996-03-08 | 1997-09-12 | Takeda Chemical Industries, Ltd. | Tricyclic compounds, their production and use |
| US7592352B2 (en) | 2003-05-06 | 2009-09-22 | Smithkline Beecham Corporation | Substituted thieno and furo-pyridines |
| WO2006027424A1 (fr) * | 2004-08-12 | 2006-03-16 | Inria Institut National De Recherche En Informatique Et En Automatique | Dispositif de contrôle de communications |
| FR2874611B1 (fr) | 2004-08-31 | 2006-11-17 | Servier Lab | Nouveaux derives d'imidazopyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| ATE381250T1 (de) | 2005-05-13 | 2007-12-15 | Sefar Ag | Leiterplatte und verfahren zu deren herstellung |
-
2007
- 2007-12-07 CN CNA2007800511626A patent/CN101605795A/zh active Pending
- 2007-12-07 CA CA002671354A patent/CA2671354A1/en not_active Abandoned
- 2007-12-07 JP JP2008548352A patent/JP5227806B2/ja not_active Expired - Fee Related
- 2007-12-07 MX MX2009006078A patent/MX2009006078A/es not_active Application Discontinuation
- 2007-12-07 AU AU2007329879A patent/AU2007329879A1/en not_active Abandoned
- 2007-12-07 EA EA200970555A patent/EA200970555A1/ru unknown
- 2007-12-07 BR BRPI0719869-8A2A patent/BRPI0719869A2/pt not_active IP Right Cessation
- 2007-12-07 EP EP07850267A patent/EP2100895B1/de not_active Not-in-force
- 2007-12-07 WO PCT/JP2007/073680 patent/WO2008069311A1/ja not_active Ceased
- 2007-12-07 KR KR1020097014200A patent/KR20090086641A/ko not_active Withdrawn
- 2007-12-07 US US12/448,094 patent/US8273761B2/en not_active Expired - Fee Related
- 2007-12-07 AT AT07850267T patent/ATE548371T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| US20100029707A1 (en) | 2010-02-04 |
| AU2007329879A1 (en) | 2008-06-12 |
| CN101605795A (zh) | 2009-12-16 |
| CA2671354A1 (en) | 2008-06-12 |
| EP2100895A1 (de) | 2009-09-16 |
| MX2009006078A (es) | 2009-09-18 |
| JPWO2008069311A1 (ja) | 2010-03-25 |
| JP5227806B2 (ja) | 2013-07-03 |
| EP2100895A4 (de) | 2009-12-23 |
| US8273761B2 (en) | 2012-09-25 |
| EP2100895B1 (de) | 2012-03-07 |
| WO2008069311A1 (ja) | 2008-06-12 |
| EA200970555A1 (ru) | 2010-02-26 |
| BRPI0719869A2 (pt) | 2014-04-15 |
| KR20090086641A (ko) | 2009-08-13 |
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