ATE545832T1 - Kryogenes kühlsystem für gefriertrocknung - Google Patents

Kryogenes kühlsystem für gefriertrocknung

Info

Publication number
ATE545832T1
ATE545832T1 AT07872179T AT07872179T ATE545832T1 AT E545832 T1 ATE545832 T1 AT E545832T1 AT 07872179 T AT07872179 T AT 07872179T AT 07872179 T AT07872179 T AT 07872179T AT E545832 T1 ATE545832 T1 AT E545832T1
Authority
AT
Austria
Prior art keywords
heat transfer
recirculation loop
cryogenic
transfer fluid
cryogene
Prior art date
Application number
AT07872179T
Other languages
English (en)
Inventor
Alan Cheng
Original Assignee
Praxair Technology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Praxair Technology Inc filed Critical Praxair Technology Inc
Application granted granted Critical
Publication of ATE545832T1 publication Critical patent/ATE545832T1/de

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00—Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/14—Mechanical aspects of preservation; Apparatus or containers therefor
    • A01N1/142—Apparatus
    • A01N1/144—Apparatus for temperature control, e.g. refrigerators or freeze-drying apparatus
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25B—REFRIGERATION MACHINES, PLANTS OR SYSTEMS; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS
    • F25B39/00—Evaporators; Condensers
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D17/00—Arrangements for circulating cooling fluids; Arrangements for circulating gas, e.g. air, within refrigerated spaces
    • F25D17/02—Arrangements for circulating cooling fluids; Arrangements for circulating gas, e.g. air, within refrigerated spaces for circulating liquids, e.g. brine
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D3/00—Devices using other cold materials; Devices using cold-storage bodies
    • F25D3/10—Devices using other cold materials; Devices using cold-storage bodies using liquefied gases, e.g. liquid air
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D2400/00—General features of, or devices for refrigerators, cold rooms, ice-boxes, or for cooling or freezing apparatus not covered by any other subclass
    • F25D2400/02—Refrigerators including a heater

Landscapes

  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Thermal Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Combustion & Propulsion (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Dentistry (AREA)
  • Molecular Biology (AREA)
  • Drying Of Solid Materials (AREA)
AT07872179T 2006-09-08 2007-09-07 Kryogenes kühlsystem für gefriertrocknung ATE545832T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US84305306P 2006-09-08 2006-09-08
PCT/US2007/019571 WO2008085208A2 (en) 2006-09-08 2007-09-07 Cryogenic refrigeration system for lyophilization

Publications (1)

Publication Number Publication Date
ATE545832T1 true ATE545832T1 (de) 2012-03-15

Family

ID=39192178

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07872179T ATE545832T1 (de) 2006-09-08 2007-09-07 Kryogenes kühlsystem für gefriertrocknung

Country Status (12)

Country Link
US (2) US8015841B2 (de)
EP (1) EP2074367B1 (de)
JP (1) JP2010502932A (de)
KR (1) KR20090057422A (de)
CN (1) CN101140126B (de)
AT (1) ATE545832T1 (de)
BR (1) BRPI0716257A2 (de)
CA (1) CA2662505C (de)
ES (1) ES2377999T3 (de)
MX (1) MX2009002569A (de)
NO (1) NO20091352L (de)
WO (1) WO2008085208A2 (de)

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DE202007001123U1 (de) * 2007-01-25 2007-06-06 KRÜGER, Günter Anlage zum Trocknen von organischen Massen
US8365539B2 (en) * 2010-02-12 2013-02-05 Massachusetts Institute Of Technology System and method for thermal process including a thermoelectric heat pump and internal heat exchanger
US8549768B2 (en) * 2011-03-11 2013-10-08 Linde Aktiengesellschaft Methods for freeze drying
CN102374724B (zh) * 2011-08-23 2015-04-29 中韩科技有限公司 具有冻干功能的制冷装置
ES2716932T3 (es) 2011-09-06 2019-06-18 Rv Holding B V Procedimiento y sistema para liofilizar composiciones inyectables, en particular composiciones farmacéuticas
WO2014144549A1 (en) 2013-03-15 2014-09-18 Biogen Idec Ma Inc. Factor ix polypeptide formulations
JP6312374B2 (ja) * 2013-06-27 2018-04-18 株式会社前川製作所 凍結乾燥システムおよび凍結乾燥方法
CN104296502A (zh) * 2013-07-19 2015-01-21 北京四环科学仪器厂有限公司 一种可不间断运行带自动化霜功能的真空冷冻干燥机制冷系统
SG10201913735SA (en) 2014-03-24 2020-03-30 Bioverativ Therapeutics Inc Lyophilized factor ix formulations
CN103968649B (zh) * 2014-05-13 2015-12-02 上海理工大学 一种冷冻干燥方法及配套设备
GB2537797B (en) * 2014-09-24 2019-01-02 The Sure Chill Company Ltd Cooling apparatus and method
US10126024B1 (en) 2014-09-26 2018-11-13 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Cryogenic heat transfer system
US10605527B2 (en) 2015-09-22 2020-03-31 Millrock Technology, Inc. Apparatus and method for developing freeze drying protocols using small batches of product
US9559312B1 (en) 2016-01-07 2017-01-31 E-Ray Optoelectronics Technology Co., Ltd. Imidazole compound, material for electronic device, electroluminescent device, and electronic device thereof
JP6902293B2 (ja) 2016-08-16 2021-07-14 レアヴィタ ビーブイ フリーズドライのための方法および装置および容器
US10113797B2 (en) 2016-09-09 2018-10-30 Sp Industries, Inc. Energy recovery in a freeze-drying system
CN106352664B (zh) * 2016-11-11 2019-01-15 中国科学院理化技术研究所 一种低温速冻冻干系统
SI3392584T1 (sl) * 2017-04-21 2020-09-30 Gea Lyophil Gmbh Zamrzovalni sušilnik in postopek za induciranje nukleacije v proizvodih
CN111278481B (zh) * 2017-10-11 2023-06-30 甘布罗伦迪亚股份公司 透析机和对透析机进行消毒的方法
CN108168221B (zh) * 2018-02-01 2023-05-30 江苏派乐滋食品有限公司 一种真空冷冻干燥装置及真空冷冻干燥物料的方法
US11293422B2 (en) 2019-08-02 2022-04-05 Thermo Finnigan Llc Methods and systems for cooling a vacuum pump
CN110986492A (zh) * 2019-12-10 2020-04-10 江西艾维斯机械有限公司 一种冷冻式干燥机及其控制方法
CN111457683B (zh) * 2020-05-19 2023-06-02 烟台大学 一种新式余热与凝水回收冻干机及其运行方法
CN111595113A (zh) * 2020-05-29 2020-08-28 雅本化学股份有限公司 一种克林霉素加工生产用稳定性好的高效纯化装置
CN112361691B (zh) * 2020-10-27 2021-11-12 北京科吉照维药剂自动化设备有限公司 生物保存装置及其制冷控制方法
CN112611166B (zh) * 2020-12-09 2022-06-03 赤水市信天中药产业开发有限公司 一种石斛饮片制备用冷冻干燥装置及干燥方法
CN115900247B (zh) * 2021-09-30 2025-02-07 泛亚气体技术（无锡）有限公司 冷冻式干燥机及其控制方法
CN114812107B (zh) * 2022-04-19 2023-03-17 山东香果冻干机械科技有限公司 一种保持食品冻干中真空度恒定的设备
CN115289738A (zh) * 2022-08-03 2022-11-04 中国科学院上海高等研究院 一种用于井下单色器的液氮冷却系统及其使用方法
CN115342603A (zh) * 2022-08-30 2022-11-15 中国科学院理化技术研究所 循环风冷冻干燥系统及方法
CN115451663B (zh) * 2022-08-30 2023-10-13 中国科学院理化技术研究所 利用循环风吸附脱水的冷冻干燥系统及方法
CN115751816B (zh) * 2022-11-30 2025-06-06 芜湖中科飞机制造有限公司 飞机实验后冷却机构
CN116972601B (zh) * 2023-09-22 2023-12-08 昆海生物技术(三亚)有限公司 一种白番茄真空冷冻干燥装置及其冷冻干燥方法

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FR2146100B2 (de) 1971-07-16 1974-03-29 Air Liquide
US4353222A (en) 1979-07-04 1982-10-12 Kyowa Vacuum Engineering, Ltd. Vacuum apparatus
FR2685066B1 (fr) 1991-12-12 1995-04-14 Guy Beurel Dispositif de lyophilisation.
US5519946A (en) 1992-03-12 1996-05-28 The Boc Group, Inc. Freeze dryer shelf
JPH0743067A (ja) * 1993-07-27 1995-02-10 Kindai Techno Res Kk 凍結乾燥装置
US5456084A (en) 1993-11-01 1995-10-10 The Boc Group, Inc. Cryogenic heat exchange system and freeze dryer
US5398426A (en) 1993-12-29 1995-03-21 Societe' De Gestion Et De Diffusion North America, Inc. Process and apparatus for desiccation
US5743023A (en) 1996-09-06 1998-04-28 Fay; John M. Method and apparatus for controlling freeze drying process
US5701745A (en) 1996-12-16 1997-12-30 Praxair Technology, Inc. Cryogenic cold shelf
US5937656A (en) 1997-05-07 1999-08-17 Praxair Technology, Inc. Nonfreezing heat exchanger
JPH11264659A (ja) * 1998-03-09 1999-09-28 Hal Co Division Of Sp Ind Inc 凍結乾燥方法および装置
US6220048B1 (en) 1998-09-21 2001-04-24 Praxair Technology, Inc. Freeze drying with reduced cryogen consumption
US6610250B1 (en) * 1999-08-23 2003-08-26 3M Innovative Properties Company Apparatus using halogenated organic fluids for heat transfer in low temperature processes requiring sterilization and methods therefor
DE20008915U1 (de) 2000-05-19 2001-06-28 Martin Christ Gefriertrocknungsanlagen GmbH, 37520 Osterode Gefriertrocknungsanlage
US8793895B2 (en) 2006-02-10 2014-08-05 Praxair Technology, Inc. Lyophilization system and method

Also Published As

Publication number Publication date
BRPI0716257A2 (pt) 2013-09-03
US20110283717A1 (en) 2011-11-24
WO2008085208A3 (en) 2009-02-12
US8015841B2 (en) 2011-09-13
ES2377999T3 (es) 2012-04-04
US8938979B2 (en) 2015-01-27
EP2074367A2 (de) 2009-07-01
CA2662505C (en) 2013-06-18
US20080060379A1 (en) 2008-03-13
NO20091352L (no) 2009-04-01
CN101140126B (zh) 2011-04-06
KR20090057422A (ko) 2009-06-05
WO2008085208A2 (en) 2008-07-17
CA2662505A1 (en) 2008-07-17
EP2074367B1 (de) 2012-02-15
MX2009002569A (es) 2009-05-13
CN101140126A (zh) 2008-03-12
JP2010502932A (ja) 2010-01-28

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