ATE542810T1 - Verfahren zur herstellung von 3,5-di-omikron-acyl-2-fluor-2-c-methyl-d-ribono gamma-lacton - Google Patents
Verfahren zur herstellung von 3,5-di-omikron-acyl-2-fluor-2-c-methyl-d-ribono gamma-lactonInfo
- Publication number
- ATE542810T1 ATE542810T1 AT07857390T AT07857390T ATE542810T1 AT E542810 T1 ATE542810 T1 AT E542810T1 AT 07857390 T AT07857390 T AT 07857390T AT 07857390 T AT07857390 T AT 07857390T AT E542810 T1 ATE542810 T1 AT E542810T1
- Authority
- AT
- Austria
- Prior art keywords
- methyl
- ribono
- lactone
- acyl
- omikron
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
- C07D317/24—Radicals substituted by singly bound oxygen or sulfur atoms esterified
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/12—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US87561706P | 2006-12-18 | 2006-12-18 | |
PCT/EP2007/063703 WO2008074693A2 (en) | 2006-12-18 | 2007-12-11 | Process for preparing 3,5-di-omicron-acyl-2-fluoro-2-c-methyl-d-ribono-gamma-lactone |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE542810T1 true ATE542810T1 (de) | 2012-02-15 |
Family
ID=39433788
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT07857390T ATE542810T1 (de) | 2006-12-18 | 2007-12-11 | Verfahren zur herstellung von 3,5-di-omikron-acyl-2-fluor-2-c-methyl-d-ribono gamma-lacton |
Country Status (13)
Country | Link |
---|---|
US (1) | US7838693B2 (de) |
EP (1) | EP2094679B1 (de) |
JP (1) | JP5148627B2 (de) |
KR (1) | KR101118413B1 (de) |
CN (1) | CN101573349B (de) |
AT (1) | ATE542810T1 (de) |
AU (1) | AU2007336365B2 (de) |
BR (1) | BRPI0720835A2 (de) |
CA (1) | CA2671856C (de) |
ES (1) | ES2379696T3 (de) |
IL (1) | IL198801A (de) |
MX (1) | MX2009006156A (de) |
WO (1) | WO2008074693A2 (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103724301A (zh) | 2012-10-10 | 2014-04-16 | 上海特化医药科技有限公司 | (2r)-2-脱氧-2,2-二取代-1,4-核糖内酯及其制备方法和用途 |
CN104918924B (zh) * | 2013-01-14 | 2018-05-11 | 吉利德制药有限责任公司 | 制备氟代内酯衍生物的方法 |
AR094466A1 (es) * | 2013-01-14 | 2015-08-05 | Hoffmann La Roche | Proceso para la obtención de un derivado de fluorlactona |
JP6394588B2 (ja) * | 2013-02-28 | 2018-09-26 | セントラル硝子株式会社 | (2R)−2−フルオロ−2−C−メチル−D−リボノ−γ−ラクトンの製造方法 |
JP6476591B2 (ja) * | 2013-06-05 | 2019-03-06 | セントラル硝子株式会社 | (2R)−2−フルオロ−2−C−メチル−D−リボノ−γ−ラクトン類の製造方法 |
CN105085445B (zh) * | 2015-08-11 | 2016-09-07 | 海门慧聚药业有限公司 | 索非布韦中间体的制备 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1243434A4 (de) * | 2000-11-30 | 2006-05-24 | Daicel Chem | Übertragungsblatt |
EP2308861B1 (de) * | 2002-03-08 | 2017-03-01 | Eisai R&D Management Co., Ltd. | Macrocyclische verbindungen verwendbar als arzneitmitteln |
ES2726998T3 (es) * | 2003-05-30 | 2019-10-11 | Gilead Pharmasset Llc | Análogos de nucleósidos fluorados modificados |
WO2006012440A2 (en) * | 2004-07-21 | 2006-02-02 | Pharmasset, Inc. | Preparation of alkyl-substituted 2-deoxy-2-fluoro-d-ribofuranosyl pyrimidines and purines and their derivatives |
PT3109244T (pt) * | 2004-09-14 | 2019-06-04 | Gilead Pharmasset Llc | ¿preparação de ribofuranosil pirimidinas e purinas 2¿-fluoro-2¿-alquil substituídas ou outras opcionalmente substituídas e os seus derivados |
-
2007
- 2007-12-11 KR KR1020097012519A patent/KR101118413B1/ko not_active IP Right Cessation
- 2007-12-11 JP JP2009541984A patent/JP5148627B2/ja not_active Expired - Fee Related
- 2007-12-11 AT AT07857390T patent/ATE542810T1/de active
- 2007-12-11 WO PCT/EP2007/063703 patent/WO2008074693A2/en active Application Filing
- 2007-12-11 EP EP07857390A patent/EP2094679B1/de not_active Not-in-force
- 2007-12-11 ES ES07857390T patent/ES2379696T3/es active Active
- 2007-12-11 US US11/953,900 patent/US7838693B2/en not_active Expired - Fee Related
- 2007-12-11 CA CA2671856A patent/CA2671856C/en not_active Expired - Fee Related
- 2007-12-11 MX MX2009006156A patent/MX2009006156A/es active IP Right Grant
- 2007-12-11 CN CN2007800467888A patent/CN101573349B/zh not_active Expired - Fee Related
- 2007-12-11 AU AU2007336365A patent/AU2007336365B2/en not_active Ceased
- 2007-12-11 BR BRPI0720835A patent/BRPI0720835A2/pt not_active IP Right Cessation
-
2009
- 2009-05-18 IL IL198801A patent/IL198801A/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JP2010513377A (ja) | 2010-04-30 |
WO2008074693A3 (en) | 2008-10-30 |
AU2007336365A1 (en) | 2008-06-26 |
EP2094679B1 (de) | 2012-01-25 |
US7838693B2 (en) | 2010-11-23 |
CN101573349B (zh) | 2013-07-10 |
CN101573349A (zh) | 2009-11-04 |
US20080145901A1 (en) | 2008-06-19 |
AU2007336365B2 (en) | 2013-03-07 |
IL198801A (en) | 2013-08-29 |
BRPI0720835A2 (pt) | 2015-09-29 |
KR20090080562A (ko) | 2009-07-24 |
WO2008074693A2 (en) | 2008-06-26 |
CA2671856A1 (en) | 2008-06-26 |
JP5148627B2 (ja) | 2013-02-20 |
EP2094679A2 (de) | 2009-09-02 |
CA2671856C (en) | 2015-02-10 |
MX2009006156A (es) | 2009-06-19 |
IL198801A0 (en) | 2010-02-17 |
ES2379696T3 (es) | 2012-04-30 |
KR101118413B1 (ko) | 2012-03-07 |
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