ATE54138T1 - Herstellung von cholecalciferolderivaten und neue hierfuer verwendete zwischenprodukte. - Google Patents
Herstellung von cholecalciferolderivaten und neue hierfuer verwendete zwischenprodukte.Info
- Publication number
- ATE54138T1 ATE54138T1 AT86117422T AT86117422T ATE54138T1 AT E54138 T1 ATE54138 T1 AT E54138T1 AT 86117422 T AT86117422 T AT 86117422T AT 86117422 T AT86117422 T AT 86117422T AT E54138 T1 ATE54138 T1 AT E54138T1
- Authority
- AT
- Austria
- Prior art keywords
- production
- intermediate products
- products used
- new intermediate
- cholecalciferol derivatives
- Prior art date
Links
- 239000013067 intermediate product Substances 0.000 title 1
- 150000003704 vitamin D3 derivatives Chemical class 0.000 title 1
- GMRQFYUYWCNGIN-NKMMMXOESA-N calcitriol Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@@H](CCCC(C)(C)O)C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C GMRQFYUYWCNGIN-NKMMMXOESA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 230000000707 stereoselective effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL77668A IL77668A (en) | 1986-01-21 | 1986-01-21 | Production of cholecalciferol derivatives and novel intermediates used therefor |
| EP86117422A EP0230600B1 (de) | 1986-01-21 | 1986-12-15 | Herstellung von Cholecalciferolderivaten und neue hierfür verwendete Zwischenprodukte |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE54138T1 true ATE54138T1 (de) | 1990-07-15 |
Family
ID=11056511
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT86117422T ATE54138T1 (de) | 1986-01-21 | 1986-12-15 | Herstellung von cholecalciferolderivaten und neue hierfuer verwendete zwischenprodukte. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4758382A (de) |
| EP (1) | EP0230600B1 (de) |
| JP (2) | JPS62169762A (de) |
| AT (1) | ATE54138T1 (de) |
| AU (1) | AU590644B2 (de) |
| DE (1) | DE3672251D1 (de) |
| IL (1) | IL77668A (de) |
| ZA (1) | ZA869054B (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4927815A (en) * | 1988-04-29 | 1990-05-22 | Wisconsin Alumni Research Foundation | Compounds effective in inducing cell differentiation and process for preparing same |
| US5218109A (en) * | 1988-07-05 | 1993-06-08 | Kuraray Co., Ltd. | Steroid compounds |
| GB9007236D0 (en) * | 1990-03-30 | 1990-05-30 | Leo Pharm Prod Ltd | Chemical compounds |
| AU650751B2 (en) * | 1991-05-28 | 1994-06-30 | Wisconsin Alumni Research Foundation | Novel synthesis of 19-nor vitamin D compounds |
| ES2093180T3 (es) * | 1991-07-05 | 1996-12-16 | Duphar Int Res | Compuesto de vitamina d, metodo de preparar este compuesto y producto intermedio de dicho metodo. |
| JP2876547B2 (ja) * | 1992-06-23 | 1999-03-31 | 呉羽化学工業株式会社 | 抗クル病剤 |
| US5464866A (en) * | 1992-08-17 | 1995-11-07 | Alcon Laboratories, Inc. | Substituted hydrindanes for the treatment of angiogenesis-dependent diseases |
| AU5018893A (en) * | 1992-08-17 | 1994-03-15 | Alcon Laboratories, Inc. | Substituted hydrindanes for the treatment of angiogenesis-dependent diseases |
| JP3306468B2 (ja) * | 1997-10-30 | 2002-07-24 | セレスティカ・ジャパン・イーエムエス株式会社 | 自動ハンダ付け機構及びその機構を用いる装置並びにそのハンダ付け方法 |
| PL188697B1 (pl) * | 1998-01-14 | 2005-03-31 | Inst Farmaceutyczny | Sposób otrzymywania pochodnych cholekalcyferolu oraz nowe związki pośrednie |
| JP4752110B2 (ja) * | 2000-12-25 | 2011-08-17 | 住友化学株式会社 | トリフルオロプロペニル化合物の製造法 |
| WO2008131267A2 (en) * | 2007-04-18 | 2008-10-30 | Johns Hopkins University | Low calcemic, highly antiproliferative, analogs of calcitriol |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3715374A (en) * | 1972-05-05 | 1973-02-06 | Wisconsin Alumni Res Found | 24,25-dihydroxycholecalciferol |
| US4069321A (en) * | 1975-10-14 | 1978-01-17 | Merck & Co., Inc. | Blocked cholecalciferol and dihydrotachysterol 3 derivatives |
| JPS5735599A (en) * | 1980-08-05 | 1982-02-26 | Chugai Pharmaceut Co Ltd | 24,25-dihydroxycholestane and its preparation |
| US4442093A (en) * | 1981-05-15 | 1984-04-10 | Kureha Kagaku Kogyo Kabushiki Kaisha | Method for administering 24,25-dihydroxycholecalciferol to persons suffering from hypercalcemia |
| ATE34977T1 (de) * | 1983-01-28 | 1988-06-15 | Hoffmann La Roche | Verfahren zur herstellung von cholecalciferolderivaten. |
| US4508651A (en) * | 1983-03-21 | 1985-04-02 | Hoffmann-La Roche Inc. | Synthesis of 1α,25-dihydroxyergocalciferol |
| EP0154185B1 (de) * | 1984-02-08 | 1988-10-05 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Calciferolderivate |
-
1986
- 1986-01-21 IL IL77668A patent/IL77668A/xx not_active IP Right Cessation
- 1986-12-01 ZA ZA869054A patent/ZA869054B/xx unknown
- 1986-12-02 AU AU66010/86A patent/AU590644B2/en not_active Ceased
- 1986-12-15 DE DE8686117422T patent/DE3672251D1/de not_active Expired - Lifetime
- 1986-12-15 AT AT86117422T patent/ATE54138T1/de not_active IP Right Cessation
- 1986-12-15 EP EP86117422A patent/EP0230600B1/de not_active Expired - Lifetime
- 1986-12-22 US US06/944,921 patent/US4758382A/en not_active Expired - Fee Related
-
1987
- 1987-01-20 JP JP62012153A patent/JPS62169762A/ja active Granted
-
1991
- 1991-11-01 JP JP3287990A patent/JP2505669B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPS62169762A (ja) | 1987-07-25 |
| IL77668A (en) | 1989-03-31 |
| AU6601086A (en) | 1987-07-23 |
| JPH0424346B2 (de) | 1992-04-24 |
| US4758382A (en) | 1988-07-19 |
| ZA869054B (en) | 1987-07-29 |
| EP0230600B1 (de) | 1990-06-27 |
| EP0230600A1 (de) | 1987-08-05 |
| DE3672251D1 (de) | 1990-08-02 |
| JP2505669B2 (ja) | 1996-06-12 |
| JPH054962A (ja) | 1993-01-14 |
| AU590644B2 (en) | 1989-11-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |