ATE540919T1 - Salz von fumarsäure und 3- (2-dimethylamino) methyl- ( cyclohex-1-yl) ) phenol un dessen kristalline formen - Google Patents

Salz von fumarsäure und 3- (2-dimethylamino) methyl- ( cyclohex-1-yl) ) phenol un dessen kristalline formen

Info

Publication number
ATE540919T1
ATE540919T1 AT06776326T AT06776326T ATE540919T1 AT E540919 T1 ATE540919 T1 AT E540919T1 AT 06776326 T AT06776326 T AT 06776326T AT 06776326 T AT06776326 T AT 06776326T AT E540919 T1 ATE540919 T1 AT E540919T1
Authority
AT
Austria
Prior art keywords
cyclohex
dimethylamino
phenol
methyl
salt
Prior art date
Application number
AT06776326T
Other languages
German (de)
English (en)
Inventor
Michael Gruss
Wolfgang Hell
Martin Szelagiewicz
Joerg Berghausen
Paul Susan De
Raumer Markus Von
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Application granted granted Critical
Publication of ATE540919T1 publication Critical patent/ATE540919T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/64Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT06776326T 2005-07-22 2006-07-20 Salz von fumarsäure und 3- (2-dimethylamino) methyl- ( cyclohex-1-yl) ) phenol un dessen kristalline formen ATE540919T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005034973A DE102005034973A1 (de) 2005-07-22 2005-07-22 Salz von Dimethylaminomethyl-phenyl-cyclohexan und dessen kristalline Formen
PCT/EP2006/007161 WO2007009793A1 (de) 2005-07-22 2006-07-20 Salz von fumarsäure und 3- (2-dimethylamino) methyl- ( cyclohex-1-yl) ) phenol un dessen kristalline formen

Publications (1)

Publication Number Publication Date
ATE540919T1 true ATE540919T1 (de) 2012-01-15

Family

ID=37101332

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06776326T ATE540919T1 (de) 2005-07-22 2006-07-20 Salz von fumarsäure und 3- (2-dimethylamino) methyl- ( cyclohex-1-yl) ) phenol un dessen kristalline formen

Country Status (14)

Country Link
EP (1) EP1907350B1 (enExample)
JP (1) JP5205260B2 (enExample)
AR (1) AR057673A1 (enExample)
AT (1) ATE540919T1 (enExample)
CA (1) CA2615741A1 (enExample)
CY (1) CY1112741T1 (enExample)
DE (1) DE102005034973A1 (enExample)
DK (1) DK1907350T3 (enExample)
ES (1) ES2380799T3 (enExample)
PE (1) PE20070375A1 (enExample)
PL (1) PL1907350T3 (enExample)
PT (1) PT1907350E (enExample)
SI (1) SI1907350T1 (enExample)
WO (1) WO2007009793A1 (enExample)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19525137C2 (de) * 1995-07-11 2003-02-27 Gruenenthal Gmbh 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbin -dungen als Zwischenprodukte zur Herstellung pharmazeutischer Wirkstoffe
DE10000312A1 (de) * 2000-01-05 2001-07-12 Gruenenthal Gmbh Substituierte Aminomethyl-Phenyl-Cyclohexanderivate
DE10218862A1 (de) * 2002-04-26 2003-11-06 Gruenenthal Gmbh Verfahren zur Chlorierung tertiärer Alkohole
DE10233048A1 (de) * 2002-07-19 2004-01-29 Grünenthal GmbH Verwendung von 1-Phenyl-3dimethylamino-propanverbindungen zur Therapie von depressiven Symptomatiken
DE10356362A1 (de) * 2003-11-28 2005-06-23 Grünenthal GmbH Verwendung von 1-Phenyl-3-dimethylamino-propanverbindungen zur Therapie von Angststörungen

Also Published As

Publication number Publication date
CY1112741T1 (el) 2016-02-10
ES2380799T3 (es) 2012-05-18
JP2009502758A (ja) 2009-01-29
PT1907350E (pt) 2012-03-29
CA2615741A1 (en) 2007-01-25
EP1907350B1 (de) 2012-01-11
DK1907350T3 (da) 2012-05-07
EP1907350A1 (de) 2008-04-09
WO2007009793A1 (de) 2007-01-25
JP5205260B2 (ja) 2013-06-05
SI1907350T1 (sl) 2012-04-30
PE20070375A1 (es) 2007-05-12
AR057673A1 (es) 2007-12-12
DE102005034973A1 (de) 2007-02-15
PL1907350T3 (pl) 2012-06-29

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