ATE536368T1 - Konjugate von zytotoxischen verbindungen mit peptiden - Google Patents
Konjugate von zytotoxischen verbindungen mit peptidenInfo
- Publication number
- ATE536368T1 ATE536368T1 AT07839646T AT07839646T ATE536368T1 AT E536368 T1 ATE536368 T1 AT E536368T1 AT 07839646 T AT07839646 T AT 07839646T AT 07839646 T AT07839646 T AT 07839646T AT E536368 T1 ATE536368 T1 AT E536368T1
- Authority
- AT
- Austria
- Prior art keywords
- conjugates
- peptides
- cytotoxic compounds
- compounds
- cytotoxic
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 231100000433 cytotoxic Toxicity 0.000 title abstract 2
- 230000001472 cytotoxic effect Effects 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 230000009826 neoplastic cell growth Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Urology & Nephrology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Cardiology (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85314006P | 2006-10-20 | 2006-10-20 | |
| US91813307P | 2007-03-15 | 2007-03-15 | |
| PCT/US2007/022179 WO2008051421A2 (en) | 2006-10-20 | 2007-10-17 | Peptide-cytotoxic conjugates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE536368T1 true ATE536368T1 (de) | 2011-12-15 |
Family
ID=39325115
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07839646T ATE536368T1 (de) | 2006-10-20 | 2007-10-17 | Konjugate von zytotoxischen verbindungen mit peptiden |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8236762B2 (de) |
| EP (1) | EP2084178B1 (de) |
| JP (1) | JP4988851B2 (de) |
| KR (1) | KR20090074806A (de) |
| AT (1) | ATE536368T1 (de) |
| AU (1) | AU2007309585B2 (de) |
| BR (1) | BRPI0718287A2 (de) |
| CA (1) | CA2666991A1 (de) |
| ES (1) | ES2378902T3 (de) |
| IL (1) | IL198202A0 (de) |
| MX (1) | MX2009004178A (de) |
| NZ (1) | NZ577039A (de) |
| RU (1) | RU2457218C2 (de) |
| WO (1) | WO2008051421A2 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1624884A4 (de) * | 2003-04-22 | 2009-08-05 | Ipsen Pharma | Somatostatin-vektoren |
| JP5584236B2 (ja) * | 2009-02-20 | 2014-09-03 | イプセン ファルマ ソシエテ パール アクシオン サンプリフィエ | 神経ペプチドｙ受容体結合化合物を有する細胞毒性コンジュゲート |
| US9371340B2 (en) | 2012-08-16 | 2016-06-21 | Momentive Performance Materials Inc. | Dehydrogenative silylation, hydrosilylation and crosslinking using cobalt catalysts |
| US9447125B2 (en) | 2012-08-16 | 2016-09-20 | Momentive Performance Materials Inc. | Reusable homogeneous cobalt pyridine diimine catalysts for dehydrogenative silylation and tandem dehydrogenative-silylation-hydrogenation |
| WO2022035843A1 (en) * | 2020-08-12 | 2022-02-17 | Nanomedicine Innovation Center, Llc | Topoisomerase inhibitors |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1589151A (zh) | 2001-09-21 | 2005-03-02 | 图兰恩教育基金管理人 | 诊断或治疗性促生长素抑制素或铃蟾肽类似物的连接物及其用途 |
| CA2521965A1 (en) * | 2003-04-11 | 2004-10-28 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R | Somatostatin-dopamine chimeric analogs |
| EP1624884A4 (de) | 2003-04-22 | 2009-08-05 | Ipsen Pharma | Somatostatin-vektoren |
-
2007
- 2007-10-17 RU RU2009118961/04A patent/RU2457218C2/ru not_active IP Right Cessation
- 2007-10-17 AT AT07839646T patent/ATE536368T1/de active
- 2007-10-17 CA CA002666991A patent/CA2666991A1/en not_active Abandoned
- 2007-10-17 BR BRPI0718287-2A patent/BRPI0718287A2/pt not_active IP Right Cessation
- 2007-10-17 MX MX2009004178A patent/MX2009004178A/es active IP Right Grant
- 2007-10-17 EP EP07839646A patent/EP2084178B1/de active Active
- 2007-10-17 NZ NZ577039A patent/NZ577039A/en not_active IP Right Cessation
- 2007-10-17 JP JP2009533362A patent/JP4988851B2/ja not_active Expired - Fee Related
- 2007-10-17 US US12/311,961 patent/US8236762B2/en not_active Expired - Fee Related
- 2007-10-17 KR KR1020097010248A patent/KR20090074806A/ko not_active Abandoned
- 2007-10-17 AU AU2007309585A patent/AU2007309585B2/en not_active Ceased
- 2007-10-17 WO PCT/US2007/022179 patent/WO2008051421A2/en not_active Ceased
- 2007-10-17 ES ES07839646T patent/ES2378902T3/es active Active
-
2009
- 2009-04-19 IL IL198202A patent/IL198202A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2084178A2 (de) | 2009-08-05 |
| KR20090074806A (ko) | 2009-07-07 |
| EP2084178A4 (de) | 2009-10-28 |
| ES2378902T3 (es) | 2012-04-18 |
| MX2009004178A (es) | 2009-09-07 |
| AU2007309585B2 (en) | 2011-11-17 |
| NZ577039A (en) | 2011-11-25 |
| US8236762B2 (en) | 2012-08-07 |
| RU2009118961A (ru) | 2010-11-27 |
| BRPI0718287A2 (pt) | 2013-11-19 |
| US20100113367A1 (en) | 2010-05-06 |
| AU2007309585A1 (en) | 2008-05-02 |
| JP2010506924A (ja) | 2010-03-04 |
| WO2008051421A2 (en) | 2008-05-02 |
| RU2457218C2 (ru) | 2012-07-27 |
| JP4988851B2 (ja) | 2012-08-01 |
| IL198202A0 (en) | 2011-08-01 |
| EP2084178B1 (de) | 2011-12-07 |
| WO2008051421A3 (en) | 2008-12-11 |
| CA2666991A1 (en) | 2008-05-02 |
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