ATE535813T1 - Reduzierte kreuzreaktivität mit hydrophoben arzneistoffanalyt-stoffwechselprodukten zeigende immuntestverfahren - Google Patents

Reduzierte kreuzreaktivität mit hydrophoben arzneistoffanalyt-stoffwechselprodukten zeigende immuntestverfahren

Info

Publication number
ATE535813T1
ATE535813T1 AT08769692T AT08769692T ATE535813T1 AT E535813 T1 ATE535813 T1 AT E535813T1 AT 08769692 T AT08769692 T AT 08769692T AT 08769692 T AT08769692 T AT 08769692T AT E535813 T1 ATE535813 T1 AT E535813T1
Authority
AT
Austria
Prior art keywords
reactivity
hydrophobic drug
reduced cross
testing procedures
showing reduced
Prior art date
Application number
AT08769692T
Other languages
English (en)
Inventor
Elaine Brate
David Finley
Shelley Holets-Mccormack
David Pacenti
Ryan Piktel
Michelle Shields
Thomas Spring
Philip Wang
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE535813T1 publication Critical patent/ATE535813T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9493Immunosupressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT08769692T 2007-05-24 2008-05-23 Reduzierte kreuzreaktivität mit hydrophoben arzneistoffanalyt-stoffwechselprodukten zeigende immuntestverfahren ATE535813T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94006207P 2007-05-24 2007-05-24
PCT/US2008/064688 WO2008147982A1 (en) 2007-05-24 2008-05-23 Immunoassays exhibiting reduced cross-reactivity with hydrophobic drug analyte metabolites

Publications (1)

Publication Number Publication Date
ATE535813T1 true ATE535813T1 (de) 2011-12-15

Family

ID=39708486

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08769692T ATE535813T1 (de) 2007-05-24 2008-05-23 Reduzierte kreuzreaktivität mit hydrophoben arzneistoffanalyt-stoffwechselprodukten zeigende immuntestverfahren

Country Status (7)

Country Link
US (1) US8288111B2 (de)
EP (1) EP2174137B1 (de)
JP (1) JP5174898B2 (de)
AT (1) ATE535813T1 (de)
CA (1) CA2685830C (de)
ES (1) ES2377167T3 (de)
WO (1) WO2008147982A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2174137B1 (de) 2007-05-24 2011-11-30 Abbott Laboratories Reduzierte kreuzreaktivität mit hydrophoben arzneistoffanalyt-stoffwechselprodukten zeigende immuntestverfahren
US7910378B2 (en) * 2007-12-14 2011-03-22 Siemens Healthcare Diagnostics Inc. Methods for detection of hydrophobic drugs
US8652788B2 (en) * 2009-12-02 2014-02-18 Abbott Laboratories Assay for diagnosis of cardiac myocyte damage
JP5798720B2 (ja) * 2010-03-30 2015-10-21 積水メディカル株式会社 ヒトc反応性タンパク質(crp)測定用イムノクロマト試薬
AU2011317073B2 (en) 2010-10-22 2016-04-07 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes
US8409807B2 (en) 2010-10-22 2013-04-02 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes
US8563298B2 (en) 2010-10-22 2013-10-22 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes
WO2012166198A1 (en) 2011-05-27 2012-12-06 Abbott Point Of Care Inc. Tsh antibodies for point-of-care immunoassay formats
EP2715356B1 (de) 2011-05-27 2017-04-26 Abbott Point of Care Inc. Tsh-immunoassays mit scavenger-reagenzien für kreuzreagierende endokrine glykoprotein-hormon- analoga
CA2836236C (en) 2011-05-27 2020-04-28 Abbott Point Of Care Inc. Tsh immunoassays and processes for performing tsh immunoassays in the presence of endogenous contaminants in restricted wash formats
EP2839038B1 (de) 2012-04-20 2019-01-16 T2 Biosystems, Inc. Zusammensetzungen und verfahren für den nachweis einer candida-spezies
EP2930514B1 (de) * 2012-12-05 2019-08-28 Konica Minolta, Inc. Verfahren zur unterdrückung von nichtspezifischen signalen von verunreinigungen in einem immunoassay unter verwendung von oberflächenplasmonen-fluoreszenzspektroskopie (spfs)
WO2017127731A1 (en) 2016-01-21 2017-07-27 T2 Biosystems, Inc. Nmr methods and systems for the rapid detection of bacteria
EP3587560A4 (de) 2017-01-27 2020-12-16 Kaneka Corporation Endodermale zellmasse und verfahren zur herstellung einer beliebigen von drei primärkeimschichtzellmassen aus pluripotenten zellen
JP7233669B2 (ja) * 2017-05-22 2023-03-07 国立大学法人金沢大学 双性イオンを含む難溶性物質溶解剤
WO2019131380A1 (ja) 2017-12-25 2019-07-04 富士レビオ株式会社 マクロライド系免疫抑制剤についての血液検査方法
CN112014555B (zh) * 2020-08-31 2023-08-08 武汉生之源生物科技股份有限公司 一种酶标抗体缓冲液、试剂r1和肌酸激酶同工酶测定试剂盒

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5169773A (en) 1984-10-04 1992-12-08 Sandoz Ltd. Monoclonal antibodies to cyclosporins
EP0314862A1 (de) 1984-10-04 1989-05-10 Sandoz Ag Immunogenische Konjugate, die Cyclosporine enthalten
US5427960A (en) 1987-03-27 1995-06-27 Abbott Laboratories Fluorescence polarization assay for cyclosporin A and metabolites and related immunogens and antibodies
EP0283801A3 (de) 1987-03-27 1990-05-30 Abbott Laboratories Fluoreszenz-Polarisations-Test für Cyclosporin A und Metaboliten und verwandte Immunogene und Antikörper
US5239057A (en) 1987-03-27 1993-08-24 Abbott Laboratories Fluorescence polarization assay for cyclosporin a and metabolites and related immunogens and antibodies
US5006309A (en) 1988-04-22 1991-04-09 Abbott Laboratories Immunoassay device with liquid transfer between wells by washing
US5089424A (en) 1988-06-14 1992-02-18 Abbott Laboratories Method and apparatus for heterogeneous chemiluminescence assay
US5063081A (en) 1988-11-14 1991-11-05 I-Stat Corporation Method of manufacturing a plurality of uniform microfabricated sensing devices having an immobilized ligand receptor
US5135875A (en) 1990-08-15 1992-08-04 Abbott Laboratories Protein precipitation reagent
CA2048302A1 (en) 1990-08-15 1992-02-16 Victoria P. Meucci Solubilization reagent for biological test samples
EP0473961B1 (de) 1990-08-15 1996-01-03 Abbott Laboratories Immunotestreagenzien und Verfahren zur Bestimmung von Cyclosporin
CA2055813A1 (en) * 1990-11-20 1992-05-21 Dariush Davalian Cyclosporin immunoassay
US5506114A (en) 1992-02-07 1996-04-09 Osborn Laboratories Methods and kits for detecting the presence or concentration of biological analytes
US6664114B1 (en) 1992-08-03 2003-12-16 Sapidyne Instruments, Inc. Solid phase assay for detection of ligands
US6777198B2 (en) 2000-10-11 2004-08-17 Pharmacia Diagnostics Ab Assay method and kit therefor
US7419821B2 (en) 2002-03-05 2008-09-02 I-Stat Corporation Apparatus and methods for analyte measurement and immunoassay
US20040018577A1 (en) 2002-07-29 2004-01-29 Emerson Campbell John Lewis Multiple hybrid immunoassay
US7723099B2 (en) 2003-09-10 2010-05-25 Abbott Point Of Care Inc. Immunoassay device with immuno-reference electrode
US7682833B2 (en) 2003-09-10 2010-03-23 Abbott Point Of Care Inc. Immunoassay device with improved sample closure
EP1875250B1 (de) 2005-04-06 2010-01-27 Abbott Laboratories Verfahren zur messung immunsuppressiver tacrolimus-, sirolimus- und cyclosporin-a-komplexe in einer blutprobe
US7575875B2 (en) * 2005-10-13 2009-08-18 Abbott Laboratories, Inc. Method of tacrolimus extraction and quantification using aqueous detergents
US7256008B2 (en) 2006-01-06 2007-08-14 Abbott Laboratories Determination of concentration of FK778 by competitive immunoassay
US8022188B2 (en) 2006-04-24 2011-09-20 Abbott Laboratories Immunosuppressant binding antibodies and methods of obtaining and using same
US7883855B2 (en) 2006-07-21 2011-02-08 Abbott Laboratories Immunosuppressant drug extraction reagent for immunoassays
WO2008082982A1 (en) 2006-12-29 2008-07-10 Abbott Laboratories Improved assay for immunosuppressant drugs
US7914999B2 (en) * 2006-12-29 2011-03-29 Abbott Laboratories Non-denaturing lysis reagent
JP5450092B2 (ja) 2006-12-29 2014-03-26 アボット・ラボラトリーズ 全血中の分子または薬物の検出のための診断検査
WO2008082984A2 (en) 2006-12-29 2008-07-10 Abbott Laboratories Non-denaturing lysis reagent for use with capture-in-solution immunoassay
EP2174137B1 (de) 2007-05-24 2011-11-30 Abbott Laboratories Reduzierte kreuzreaktivität mit hydrophoben arzneistoffanalyt-stoffwechselprodukten zeigende immuntestverfahren

Also Published As

Publication number Publication date
EP2174137B1 (de) 2011-11-30
US8288111B2 (en) 2012-10-16
CA2685830C (en) 2012-12-18
ES2377167T3 (es) 2012-03-23
US20080311676A1 (en) 2008-12-18
EP2174137A1 (de) 2010-04-14
JP5174898B2 (ja) 2013-04-03
CA2685830A1 (en) 2008-12-04
JP2010528295A (ja) 2010-08-19
WO2008147982A1 (en) 2008-12-04

Similar Documents

Publication Publication Date Title
ATE535813T1 (de) Reduzierte kreuzreaktivität mit hydrophoben arzneistoffanalyt-stoffwechselprodukten zeigende immuntestverfahren
EP3208617A3 (de) Lipidomische biomarker zur prognose kardiosvaskulärer ergebnisse bei patienten mit erkrankung der herzkranzgefässe ohne statinbehandlung
WO2013068374A3 (en) Lipidomic biomarkers for the prediction of cardiovascular outcomes in coronary artery disease patients undergoing statin treatment
MX2010006484A (es) Composiciones y metodos para detectar anticuerpos de infidelidad de transcripcion (tiab).
ES2500066T3 (es) Anticuerpos frente a ferroportina y métodos de uso
EA201291260A1 (ru) Антитело против trop-2 человека, обладающее противоопухолевой активностью in vivo
SG10201408392PA (en) Methods of determining patient response by measurement of her-3
AR053948A1 (es) Deteccion de un antigeno diana independientemente de la presencia o ausencia de un anticuerpo terapeutico correspondiente
WO2010051544A3 (en) Rapid homogeneous diagnostic testing platform based on lanthanide fluorescent resonance energy transfer
NZ596659A (en) Bulbless spectrometer
BR112013021666A2 (pt) detecção de capacitância em ensaio eletroquímico com compensação de tempo de amostragem aprimorada
BR112014014284A2 (pt) aparelho e método para detecção de partículas magnéticas em um campo de visão, e, programa de computador
BR112012021590A2 (pt) detecção de capacitância em ensaio eletroquímico
NZ602840A (en) Immuno-pet imaging of antibodies and immunoconjugates and uses therefor
EP2490025A3 (de) Verfahren, Anordnung und Verwendung davon
RU2013105265A (ru) Способ диагностики рака поджелудочной железы
EP2155185A4 (de) Nachweis von succinylaceton
SG170051A1 (en) T cell assays
WO2012047009A3 (en) Diagnostic apparatus and diagnostic method using the same
GB201014837D0 (en) Biomarker signatures and uses thereof
GB2502007A (en) Assay assembly and method
BR112014031958A2 (pt) bag3 como marcador de tecido e soro bioquímico
WO2010031749A9 (en) Compositions and methods for detecting tlr3
EA201400571A1 (ru) Специфичные к трансресвератролу антитела и их применение
EA201300260A1 (ru) Микрочипы с малыми молекулами и способы их изготовления и применения