ATE535813T1 - Reduzierte kreuzreaktivität mit hydrophoben arzneistoffanalyt-stoffwechselprodukten zeigende immuntestverfahren - Google Patents
Reduzierte kreuzreaktivität mit hydrophoben arzneistoffanalyt-stoffwechselprodukten zeigende immuntestverfahrenInfo
- Publication number
- ATE535813T1 ATE535813T1 AT08769692T AT08769692T ATE535813T1 AT E535813 T1 ATE535813 T1 AT E535813T1 AT 08769692 T AT08769692 T AT 08769692T AT 08769692 T AT08769692 T AT 08769692T AT E535813 T1 ATE535813 T1 AT E535813T1
- Authority
- AT
- Austria
- Prior art keywords
- reactivity
- hydrophobic drug
- reduced cross
- testing procedures
- showing reduced
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/9493—Immunosupressants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US94006207P | 2007-05-24 | 2007-05-24 | |
PCT/US2008/064688 WO2008147982A1 (en) | 2007-05-24 | 2008-05-23 | Immunoassays exhibiting reduced cross-reactivity with hydrophobic drug analyte metabolites |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE535813T1 true ATE535813T1 (de) | 2011-12-15 |
Family
ID=39708486
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT08769692T ATE535813T1 (de) | 2007-05-24 | 2008-05-23 | Reduzierte kreuzreaktivität mit hydrophoben arzneistoffanalyt-stoffwechselprodukten zeigende immuntestverfahren |
Country Status (7)
Country | Link |
---|---|
US (1) | US8288111B2 (de) |
EP (1) | EP2174137B1 (de) |
JP (1) | JP5174898B2 (de) |
AT (1) | ATE535813T1 (de) |
CA (1) | CA2685830C (de) |
ES (1) | ES2377167T3 (de) |
WO (1) | WO2008147982A1 (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5174898B2 (ja) | 2007-05-24 | 2013-04-03 | アボット・ラボラトリーズ | 疎水性薬物検体代謝産物との交差反応性が低下している免疫アッセイ |
US7910378B2 (en) * | 2007-12-14 | 2011-03-22 | Siemens Healthcare Diagnostics Inc. | Methods for detection of hydrophobic drugs |
US8652788B2 (en) * | 2009-12-02 | 2014-02-18 | Abbott Laboratories | Assay for diagnosis of cardiac myocyte damage |
JP5798720B2 (ja) * | 2010-03-30 | 2015-10-21 | 積水メディカル株式会社 | ヒトc反応性タンパク質(crp)測定用イムノクロマト試薬 |
US8409807B2 (en) | 2010-10-22 | 2013-04-02 | T2 Biosystems, Inc. | NMR systems and methods for the rapid detection of analytes |
CA3155334A1 (en) | 2010-10-22 | 2012-04-26 | T2 Biosystems, Inc. | NMR SYSTEMS AND METHODS FOR RAPID ANALYTE DETECTION |
US8563298B2 (en) | 2010-10-22 | 2013-10-22 | T2 Biosystems, Inc. | NMR systems and methods for the rapid detection of analytes |
JP5938471B2 (ja) | 2011-05-27 | 2016-06-22 | アボット ポイント オブ ケア インコーポレイテッド | Tsh免疫アッセイ及び内在性夾雑物の存在下におけるtsh免疫アッセイを限定的な洗浄フォーマットで実施するための方法 |
US9199234B2 (en) | 2011-05-27 | 2015-12-01 | Abbott Point Of Care Inc. | TSH antibodies for point-of-care immunoassay formats |
WO2012166200A1 (en) | 2011-05-27 | 2012-12-06 | Abbott Point Of Care Inc. | Tsh immunoassays employing scavenging reagents for cross-reacting endocrine glycoprotein hormone analogues |
US9562271B2 (en) | 2012-04-20 | 2017-02-07 | T2 Biosystems, Inc. | Compositions and methods for detection of Candida species |
WO2014087802A1 (ja) * | 2012-12-05 | 2014-06-12 | コニカミノルタ株式会社 | 表面プラズモン励起増強蛍光分光法(spfs)を用いた免疫測定法における夾雑物由来の非特異的シグナルの抑制方法 |
EP3405479A4 (de) | 2016-01-21 | 2019-08-21 | T2 Biosystems, Inc. | Nmr-verfahren und -systeme zur schnellen detektion von bakterien |
KR102448428B1 (ko) | 2017-01-27 | 2022-09-30 | 가부시키가이샤 가네카 | 내배엽계 세포 집단, 및 다능성 세포로부터 3배엽 중 어느 하나의 세포 집단을 제조하는 방법 |
JP7233669B2 (ja) * | 2017-05-22 | 2023-03-07 | 国立大学法人金沢大学 | 双性イオンを含む難溶性物質溶解剤 |
CN111512154B (zh) | 2017-12-25 | 2022-05-27 | 富士瑞必欧株式会社 | 针对大环内酯类免疫抑制剂的血液检测方法 |
CN112014555B (zh) * | 2020-08-31 | 2023-08-08 | 武汉生之源生物科技股份有限公司 | 一种酶标抗体缓冲液、试剂r1和肌酸激酶同工酶测定试剂盒 |
WO2024137034A1 (en) * | 2022-12-21 | 2024-06-27 | Siemens Healthcare Diagnostics Inc. | Cyclosporine-acridinium esters and methods of production and use thereof |
Family Cites Families (29)
Publication number | Priority date | Publication date | Assignee | Title |
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US5169773A (en) * | 1984-10-04 | 1992-12-08 | Sandoz Ltd. | Monoclonal antibodies to cyclosporins |
DE3587342T2 (de) | 1984-10-04 | 1993-12-02 | Sandoz Ag | Cyclosporine. |
US5427960A (en) * | 1987-03-27 | 1995-06-27 | Abbott Laboratories | Fluorescence polarization assay for cyclosporin A and metabolites and related immunogens and antibodies |
US5239057A (en) * | 1987-03-27 | 1993-08-24 | Abbott Laboratories | Fluorescence polarization assay for cyclosporin a and metabolites and related immunogens and antibodies |
EP0283801A3 (de) | 1987-03-27 | 1990-05-30 | Abbott Laboratories | Fluoreszenz-Polarisations-Test für Cyclosporin A und Metaboliten und verwandte Immunogene und Antikörper |
US5006309A (en) * | 1988-04-22 | 1991-04-09 | Abbott Laboratories | Immunoassay device with liquid transfer between wells by washing |
US5089424A (en) * | 1988-06-14 | 1992-02-18 | Abbott Laboratories | Method and apparatus for heterogeneous chemiluminescence assay |
US5063081A (en) * | 1988-11-14 | 1991-11-05 | I-Stat Corporation | Method of manufacturing a plurality of uniform microfabricated sensing devices having an immobilized ligand receptor |
ES2084069T3 (es) * | 1990-08-15 | 1996-05-01 | Abbott Lab | Reactivos de inmunoensayo y metodo para la determinacion de ciclosporina. |
CA2048302A1 (en) | 1990-08-15 | 1992-02-16 | Victoria P. Meucci | Solubilization reagent for biological test samples |
US5135875A (en) * | 1990-08-15 | 1992-08-04 | Abbott Laboratories | Protein precipitation reagent |
DE69133095T2 (de) * | 1990-11-20 | 2003-03-27 | Dade Behring Marburg Gmbh | Cyclosporin-Immunoassay |
US5506114A (en) * | 1992-02-07 | 1996-04-09 | Osborn Laboratories | Methods and kits for detecting the presence or concentration of biological analytes |
US6664114B1 (en) * | 1992-08-03 | 2003-12-16 | Sapidyne Instruments, Inc. | Solid phase assay for detection of ligands |
US6777198B2 (en) * | 2000-10-11 | 2004-08-17 | Pharmacia Diagnostics Ab | Assay method and kit therefor |
US7419821B2 (en) * | 2002-03-05 | 2008-09-02 | I-Stat Corporation | Apparatus and methods for analyte measurement and immunoassay |
US20040018577A1 (en) * | 2002-07-29 | 2004-01-29 | Emerson Campbell John Lewis | Multiple hybrid immunoassay |
US7682833B2 (en) * | 2003-09-10 | 2010-03-23 | Abbott Point Of Care Inc. | Immunoassay device with improved sample closure |
US7723099B2 (en) * | 2003-09-10 | 2010-05-25 | Abbott Point Of Care Inc. | Immunoassay device with immuno-reference electrode |
CA2602732A1 (en) * | 2005-04-06 | 2006-10-12 | Abbott Laboratories | Methods to measure immunosuppressive tacrolimus, sirolimus, and cyclosporin a complexes in a blood sample |
US7575875B2 (en) * | 2005-10-13 | 2009-08-18 | Abbott Laboratories, Inc. | Method of tacrolimus extraction and quantification using aqueous detergents |
US7256008B2 (en) * | 2006-01-06 | 2007-08-14 | Abbott Laboratories | Determination of concentration of FK778 by competitive immunoassay |
US8022188B2 (en) * | 2006-04-24 | 2011-09-20 | Abbott Laboratories | Immunosuppressant binding antibodies and methods of obtaining and using same |
US7883855B2 (en) * | 2006-07-21 | 2011-02-08 | Abbott Laboratories | Immunosuppressant drug extraction reagent for immunoassays |
EP2118656B1 (de) | 2006-12-29 | 2012-08-29 | Abbott Laboratories | Verbessertes testverfahren für immunsuppressiva |
CA2673314C (en) | 2006-12-29 | 2014-03-11 | Abbott Laboratories | Non-denaturing lysis reagent for use with capture-in-solution immunoassay |
ES2405364T3 (es) | 2006-12-29 | 2013-05-30 | Abbott Laboratories | Ensayo diagnóstico para la detección de una molécula o fármaco en sangre entera |
US7914999B2 (en) * | 2006-12-29 | 2011-03-29 | Abbott Laboratories | Non-denaturing lysis reagent |
JP5174898B2 (ja) | 2007-05-24 | 2013-04-03 | アボット・ラボラトリーズ | 疎水性薬物検体代謝産物との交差反応性が低下している免疫アッセイ |
-
2008
- 2008-05-23 JP JP2010509567A patent/JP5174898B2/ja not_active Expired - Fee Related
- 2008-05-23 WO PCT/US2008/064688 patent/WO2008147982A1/en active Application Filing
- 2008-05-23 US US12/126,316 patent/US8288111B2/en active Active
- 2008-05-23 AT AT08769692T patent/ATE535813T1/de active
- 2008-05-23 EP EP08769692A patent/EP2174137B1/de active Active
- 2008-05-23 CA CA2685830A patent/CA2685830C/en not_active Expired - Fee Related
- 2008-05-23 ES ES08769692T patent/ES2377167T3/es active Active
Also Published As
Publication number | Publication date |
---|---|
EP2174137B1 (de) | 2011-11-30 |
JP2010528295A (ja) | 2010-08-19 |
US20080311676A1 (en) | 2008-12-18 |
ES2377167T3 (es) | 2012-03-23 |
EP2174137A1 (de) | 2010-04-14 |
US8288111B2 (en) | 2012-10-16 |
JP5174898B2 (ja) | 2013-04-03 |
CA2685830A1 (en) | 2008-12-04 |
CA2685830C (en) | 2012-12-18 |
WO2008147982A1 (en) | 2008-12-04 |
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