ATE53030T1 - Verbindung mit entzuendungshemmender wirkung, verfahren zu ihrer herstellung und pharmazeutische praeparate die sie enthalten. - Google Patents

Verbindung mit entzuendungshemmender wirkung, verfahren zu ihrer herstellung und pharmazeutische praeparate die sie enthalten.

Info

Publication number
ATE53030T1
ATE53030T1 AT84103220T AT84103220T ATE53030T1 AT E53030 T1 ATE53030 T1 AT E53030T1 AT 84103220 T AT84103220 T AT 84103220T AT 84103220 T AT84103220 T AT 84103220T AT E53030 T1 ATE53030 T1 AT E53030T1
Authority
AT
Austria
Prior art keywords
production
pharmaceutical preparations
preparations containing
group
inflammatory compound
Prior art date
Application number
AT84103220T
Other languages
English (en)
Inventor
Giuseppe Quadro
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Application granted granted Critical
Publication of ATE53030T1 publication Critical patent/ATE53030T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C331/00—Derivatives of thiocyanic acid or of isothiocyanic acid
    • C07C331/16—Isothiocyanates
    • C07C331/28—Isothiocyanates having isothiocyanate groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C07D215/46—Nitrogen atoms attached in position 4 with hydrocarbon radicals, substituted by nitrogen atoms, attached to said nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/50—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT84103220T 1983-04-06 1984-03-23 Verbindung mit entzuendungshemmender wirkung, verfahren zu ihrer herstellung und pharmazeutische praeparate die sie enthalten. ATE53030T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT20468/83A IT1205640B (it) 1983-04-06 1983-04-06 Nuovi composti ad attivita' antiinfiammatoria,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
EP84103220A EP0123146B1 (de) 1983-04-06 1984-03-23 Verbindung mit entzündungshemmender Wirkung, Verfahren zu ihrer Herstellung und pharmazeutische Präparate die sie enthalten

Publications (1)

Publication Number Publication Date
ATE53030T1 true ATE53030T1 (de) 1990-06-15

Family

ID=11167401

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84103220T ATE53030T1 (de) 1983-04-06 1984-03-23 Verbindung mit entzuendungshemmender wirkung, verfahren zu ihrer herstellung und pharmazeutische praeparate die sie enthalten.

Country Status (9)

Country Link
US (1) US4839366A (de)
EP (1) EP0123146B1 (de)
JP (1) JPS59210084A (de)
AT (1) ATE53030T1 (de)
DE (2) DE123146T1 (de)
ES (1) ES531318A0 (de)
IT (1) IT1205640B (de)
MY (1) MY102090A (de)
ZA (1) ZA842423B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4889935A (en) * 1987-12-18 1989-12-26 American Home Products Corporation Aminoguanidine derivatives
DE69021213T2 (de) * 1990-12-20 1996-02-29 Ibm Modulare Pufferspeicherung für ein paketvermitteltes Netzwerk.
RU2202344C2 (ru) 1998-03-26 2003-04-20 Джапан Тобакко Инк. Антагонисты ноцицептина, производные амида, аналгетик, способ инициирования антагонистического действия к ноцицептину, способ лечения боли, фармацевтические композиции
SE0004055D0 (sv) 2000-11-06 2000-11-06 Astrazeneca Ab N-type calcium channel antagonists for the treatment of pain
US7045589B2 (en) * 2002-11-15 2006-05-16 A.P. Pharma, Inc. Bioerodible poly(ortho esters) from dioxane-based di(ketene acetals), and block copolymers containing them

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE47458B1 (en) * 1977-11-07 1984-03-21 Leo Pharm Prod Ltd Quinolylguanidine derivatives
US4680300A (en) * 1985-01-10 1987-07-14 Syntex (U.S.A.) Inc. Anti-inflammatory guanidines

Also Published As

Publication number Publication date
JPS59210084A (ja) 1984-11-28
EP0123146A2 (de) 1984-10-31
EP0123146B1 (de) 1990-05-23
US4839366A (en) 1989-06-13
ES8505178A1 (es) 1985-05-16
ES531318A0 (es) 1985-05-16
JPH0251554B2 (de) 1990-11-07
DE123146T1 (de) 1985-02-14
IT8320468A0 (it) 1983-04-06
DE3482324D1 (de) 1990-06-28
IT1205640B (it) 1989-03-23
EP0123146A3 (en) 1987-03-11
MY102090A (en) 1992-03-31
ZA842423B (en) 1984-11-28

Similar Documents

Publication Publication Date Title
ATE25974T1 (de) Acyl-substituierte derivate von 1,2,3,4tetrahydroisochinolin-3-carboxysaeuren, ihre salze, diese enthaltende arzneimittel und verfahren zu ihrer herstellung.
DK159757C (da) Anvendelse af naphthalenderivater til fremstilling af et medikament til behandling eller profylakse af inflammation ved topisk administration og farmaceutisk praeparat til topisk anvendelse indeholdende naphthalenderivaterne
DE68926403D1 (de) Peptid-Verbindungen, deren Verfahren zur Herstellung und sie enthaltende pharmazeutische Zusammensetzung
MX11031A (es) Proceso para la preparacion de nuevas 1-fenil-3-naftaleniloxipropanaminas producto obtenido y composicion farmaceutica que lo incluye.
ATE60579T1 (de) Pyrrolidinamid-derivate mit antipropylendopeptidase-wirkung, zusammenstellungen, die sie enthalten, verfahren zu ihrer herstellung und heilmittel, die sie enthalten.
DE3688087D1 (de) Cephemverbindungen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate.
ATE53030T1 (de) Verbindung mit entzuendungshemmender wirkung, verfahren zu ihrer herstellung und pharmazeutische praeparate die sie enthalten.
ATE71944T1 (de) Thiazolderivate, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen, die sie enthalten.
ES8307224A1 (es) Un metodo para preparar derivados de pirazolina.
ATE37369T1 (de) Eine thiazinverbindung, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
ATE56707T1 (de) Imidazolverbindungen, verfahren zu deren herstellung und deren pharmazeutische zusammensetzungen.
FR2456744A1 (fr) Derives de la pyrazolo (1,5-c)quinazoline, procede de preparation de ces derives et medicaments contenant ces derniers
ES8702392A1 (es) Un procedimiento para preparar compuestos heterociclicos, en particular compuestos con un anillo de tiadiazinona
ES8300747A1 (es) Procedimiento para la preparacion de derivados de acido in- dolacetico
ATE40118T1 (de) Benzazepinderivate, ihre herstellung und ihre verwendung als arzneimittel.
FR2365555A1 (fr) Derives d'acide 2-(phenylalkylhydrazono)-propionique, procede pour leur preparation et medicaments contenant ces corps
PT91427A (pt) Processo para a preparacao de composicoes farmaceuticas contendo carbinoloimidazois anti-inflamatorios
FR2449688A1 (fr) Nouveaux derives de la pyrido(3,4-e)-as-triazine, procede de preparation de ces derives et medicaments les contenant
EP0191108A4 (de) O-aminomethylphenol verbindungen.
JPS56125340A (en) Cyclohexenone derivative
JPS5618985A (en) Furoindole compound
DE3571394D1 (en) A (-) campholenic acid ester of salicylic acid having mucosecretolytic, anti-inflammatory, analgesic antipyretic activity, suitable to provide pharmaceutically acceptable salts; a process for its preparation and pharmaceutical compositions containing the ester or the salts thereof
GEP20022796B (en) Novel Aryloxy-Alkyl-Dialkylamines
KR850006405A (ko) 메플로킨 항말라리아 화합물의 키닌산염
ES8301230A1 (es) Un procedimiento para la preparacion de 1-fenil-5-amidotetrazoles.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee