ATE529454T1 - Biokompatibles, nicht biologisch abbaubares, nichttoxisches polymer, das zur verwendung für pharmazeutische nanopartikelzusammensetzungen geeignet ist - Google Patents

Biokompatibles, nicht biologisch abbaubares, nichttoxisches polymer, das zur verwendung für pharmazeutische nanopartikelzusammensetzungen geeignet ist

Info

Publication number
ATE529454T1
ATE529454T1 AT06832316T AT06832316T ATE529454T1 AT E529454 T1 ATE529454 T1 AT E529454T1 AT 06832316 T AT06832316 T AT 06832316T AT 06832316 T AT06832316 T AT 06832316T AT E529454 T1 ATE529454 T1 AT E529454T1
Authority
AT
Austria
Prior art keywords
biocompatible
biodegradable
nanoparticle compositions
polymer suitable
toxic polymer
Prior art date
Application number
AT06832316T
Other languages
English (en)
Inventor
Anand Burman
Rama Mukherjee
Dhiraj Khattar
Sanjoy Mullick
Manu Jaggi
Manoj Singh
Mukesh Kumar
Deepak Prusthy
Pawan Gupta
Rajendran Praveen
Shobhit Singh
Original Assignee
Fresenius Kabi Oncology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fresenius Kabi Oncology Ltd filed Critical Fresenius Kabi Oncology Ltd
Application granted granted Critical
Publication of ATE529454T1 publication Critical patent/ATE529454T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/52—Amides or imides
    • C08F220/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C08F220/56—Acrylamide; Methacrylamide
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F222/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides, or nitriles thereof
    • C08F222/04—Anhydrides, e.g. cyclic anhydrides
    • C08F222/06—Maleic anhydride
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F222/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides, or nitriles thereof
    • C08F222/10—Esters
    • C08F222/12—Esters of phenols or saturated alcohols
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F226/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
    • C08F226/06—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a heterocyclic ring containing nitrogen
    • C08F226/10—N-Vinyl-pyrrolidone
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F222/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides, or nitriles thereof
    • C08F222/36—Amides or imides
    • C08F222/38—Amides
    • C08F222/385—Monomers containing two or more (meth)acrylamide groups, e.g. N,N'-methylenebisacrylamide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Inorganic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
AT06832316T 2005-12-28 2006-12-26 Biokompatibles, nicht biologisch abbaubares, nichttoxisches polymer, das zur verwendung für pharmazeutische nanopartikelzusammensetzungen geeignet ist ATE529454T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1190KO2005 2005-12-28
PCT/IN2006/000504 WO2007074476A1 (en) 2005-12-28 2006-12-26 A biocompatible, non-biodegradable, non-toxic polymer useful for nanoparticle pharmaceutical compositions

Publications (1)

Publication Number Publication Date
ATE529454T1 true ATE529454T1 (de) 2011-11-15

Family

ID=37845115

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06832316T ATE529454T1 (de) 2005-12-28 2006-12-26 Biokompatibles, nicht biologisch abbaubares, nichttoxisches polymer, das zur verwendung für pharmazeutische nanopartikelzusammensetzungen geeignet ist

Country Status (19)

Country Link
US (2) US8338562B2 (de)
EP (2) EP1971622B1 (de)
JP (1) JP2009522251A (de)
KR (2) KR20130116954A (de)
CN (1) CN101336256B (de)
AR (1) AR058866A1 (de)
AT (1) ATE529454T1 (de)
AU (1) AU2006329554C1 (de)
BR (1) BRPI0620745A2 (de)
CA (1) CA2635469A1 (de)
EA (1) EA017682B1 (de)
ES (2) ES2375740T3 (de)
HK (1) HK1123814A1 (de)
IL (1) IL192423A0 (de)
MX (1) MX2008008423A (de)
MY (1) MY148575A (de)
NZ (1) NZ569372A (de)
WO (1) WO2007074476A1 (de)
ZA (1) ZA200806548B (de)

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AU2006329554C1 (en) 2005-12-28 2013-06-20 Fresenius Kabi Oncology Limited A biocompatible, non-biodegradable, non-toxic polymer useful for nanoparticle pharmaceutical compositions
JP5420946B2 (ja) 2009-03-23 2014-02-19 富士フイルム株式会社 胆汁酸を含むミノキシジル水性組成物
CN101845120B (zh) * 2010-03-25 2011-11-16 淮阴师范学院 一种温敏和生物可降解性原位凝胶的合成方法
US8772355B2 (en) 2010-11-23 2014-07-08 Howard University Stealth polymeric particles for delivery of bioactive or diagnostic agents
US8921429B2 (en) 2010-11-23 2014-12-30 Howard University Biodegradable stealth polymeric particles fabricated using the macromonomer approach by free radical dispersion polymerization
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
PT2782584T (pt) 2011-11-23 2021-09-02 Therapeuticsmd Inc Preparações e terapias de substituição para hormonoterapias naturais combinadas
US20160066563A1 (en) * 2012-06-07 2016-03-10 David Moscatello Compositions and methods for collecting, washing, cryopreserving, recovering and return of lipoaspirates to physician for autologous adipose transfer procedures
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
RU2016143081A (ru) 2014-05-22 2018-06-26 Терапьютиксмд, Инк. Натуральные комбинированные гормонозаместительные составы и терапии
EP3151838A4 (de) * 2014-06-04 2017-11-29 Izard, Ryan Verfahren und zusammensetzungen zur oralen verabreichung an ferkel nach der geburt
CN104119475B (zh) * 2014-06-26 2016-06-15 中国人民解放军第三○九医院 一种表面功能化的微纳米聚合物凝胶粒子及其制备方法
CN104119474B (zh) * 2014-06-26 2016-06-15 中国人民解放军第三○九医院 一种表面功能化的微纳米聚合物空心粒子及其制备方法
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US10176182B2 (en) 2015-08-31 2019-01-08 International Business Machines Corporation File deletion in storage devices based on the deletion priority rules
EP3153227A1 (de) * 2015-10-07 2017-04-12 Evonik Degussa GmbH Verfahren zur herstellung von polyalkenameren für verpackungsanwendungen
CA3020153A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils

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IT1293823B1 (it) * 1997-08-05 1999-03-10 Stefano Gasparini Materiale plastico non tossico avente proprieta' di adsorbenza e assorbenza e relativo procedimento di fabbricazione
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BRPI0715299A2 (pt) * 2006-10-05 2013-07-23 The Johns Hopkins University mÉtodo para preparar nanoparticulas polimÉricas, mÉtodod para preparar uma coposiÇço micelar, micelas polimÉricas reconstituÍveis, composiÇço polimÉrica bioativa de nanopartÍculas, mÉtodo para proporcionar um medicamento a um paciente e processo para preparar composiÇÕes de nanoparticulas polimÉricas

Also Published As

Publication number Publication date
EA200801563A1 (ru) 2009-06-30
US20090318661A1 (en) 2009-12-24
EA017682B1 (ru) 2013-02-28
AR058866A1 (es) 2008-02-27
ES2425075T3 (es) 2013-10-11
ES2375740T3 (es) 2012-03-05
ZA200806548B (en) 2010-02-24
CA2635469A1 (en) 2007-07-05
CN101336256B (zh) 2012-03-28
KR20080091158A (ko) 2008-10-09
EP2172497B1 (de) 2013-05-22
AU2006329554C1 (en) 2013-06-20
IL192423A0 (en) 2008-12-29
HK1123814A1 (en) 2009-06-26
JP2009522251A (ja) 2009-06-11
US20130274211A1 (en) 2013-10-17
KR20130116954A (ko) 2013-10-24
NZ569372A (en) 2011-10-28
CN101336256A (zh) 2008-12-31
AU2006329554B2 (en) 2013-01-10
BRPI0620745A2 (pt) 2013-02-19
WO2007074476A1 (en) 2007-07-05
US8927023B2 (en) 2015-01-06
EP1971622B1 (de) 2011-10-19
AU2006329554A1 (en) 2007-07-05
MX2008008423A (es) 2008-09-23
US8338562B2 (en) 2012-12-25
MY148575A (en) 2013-04-30
EP2172497A1 (de) 2010-04-07
EP1971622A1 (de) 2008-09-24

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