ATE527358T1 - Ribosomen inaktivierendes protein vom typ-1 - Google Patents
Ribosomen inaktivierendes protein vom typ-1Info
- Publication number
- ATE527358T1 ATE527358T1 AT98928659T AT98928659T ATE527358T1 AT E527358 T1 ATE527358 T1 AT E527358T1 AT 98928659 T AT98928659 T AT 98928659T AT 98928659 T AT98928659 T AT 98928659T AT E527358 T1 ATE527358 T1 AT E527358T1
- Authority
- AT
- Austria
- Prior art keywords
- protein
- ribosome
- inactivative
- type
- conjugate
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 102100038954 60S ribosomal export protein NMD3 Human genes 0.000 abstract 1
- 241001316288 Bougainvillea spectabilis Species 0.000 abstract 1
- 101000603190 Homo sapiens 60S ribosomal export protein NMD3 Proteins 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 229940051026 immunotoxin Drugs 0.000 abstract 1
- 230000002637 immunotoxin Effects 0.000 abstract 1
- 239000002596 immunotoxin Substances 0.000 abstract 1
- 231100000608 immunotoxin Toxicity 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 238000002264 polyacrylamide gel electrophoresis Methods 0.000 abstract 1
- 230000008685 targeting Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 210000004881 tumor cell Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Botany (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP97201725 | 1997-06-06 | ||
PCT/NL1998/000336 WO1998055623A1 (en) | 1997-06-06 | 1998-06-08 | Type-1 ribosome-inactivating protein |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE527358T1 true ATE527358T1 (de) | 2011-10-15 |
Family
ID=8228417
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98928659T ATE527358T1 (de) | 1997-06-06 | 1998-06-08 | Ribosomen inaktivierendes protein vom typ-1 |
Country Status (6)
Country | Link |
---|---|
US (2) | US6680296B1 (de) |
EP (1) | EP0975762B1 (de) |
AT (1) | ATE527358T1 (de) |
AU (1) | AU8040898A (de) |
CA (1) | CA2295189C (de) |
WO (1) | WO1998055623A1 (de) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6812327B1 (en) | 1996-10-25 | 2004-11-02 | Human Genome Sciences, Inc. | Neutrokine-alpha polypeptides |
CA2407910C (en) | 2000-06-16 | 2013-03-12 | Steven M. Ruben | Antibodies that immunospecifically bind to blys |
US20030091565A1 (en) | 2000-08-18 | 2003-05-15 | Beltzer James P. | Binding polypeptides and methods based thereon |
AU2002238052A1 (en) | 2001-02-20 | 2002-09-04 | Zymogenetics, Inc. | Antibodies that bind both bcma and taci |
EP1241267A3 (de) * | 2001-03-14 | 2004-01-02 | Viscum AG | Enzym-Aktivitätstest mittels fluoreszenzmarkierter Oligonukleotid-Substrate |
CN101676728A (zh) | 2002-04-19 | 2010-03-24 | 津莫吉尼蒂克斯公司 | 细胞因子受体 |
HUE033533T2 (en) | 2003-04-30 | 2017-12-28 | Universität Zuerich | A method of treating cancer using immunotoxin |
PT1737961E (pt) * | 2004-03-19 | 2013-08-26 | Merck Patent Gmbh | Proteínas buganina modificadas, citotoxinas e métodos e utilizações das mesmas |
NZ556055A (en) * | 2004-12-21 | 2009-12-24 | Viventia Biotech Inc | Cancer specific antibody and cell surface proteins |
US9168286B2 (en) | 2005-10-13 | 2015-10-27 | Human Genome Sciences, Inc. | Methods and compositions for use in treatment of patients with autoantibody positive disease |
WO2007123765A2 (en) | 2006-03-31 | 2007-11-01 | Human Genome Sciences Inc. | Neutrokine-alpha and neutrokine-alpha splice variant |
US8263744B2 (en) | 2007-04-19 | 2012-09-11 | Viventia Biotechnologies Inc. | Binding proteins that bind to EpCAM linked to an effector molecule |
CA2700815A1 (en) | 2007-09-27 | 2009-04-02 | Viventia Biotech Inc. | Optimized nucleic acid sequences for the expression of vb4-845 |
US8715676B2 (en) * | 2008-02-27 | 2014-05-06 | Bioo Scientific Corporation | Production and uses of type I ribosome inactivating proteins |
EP2661451B1 (de) * | 2011-01-07 | 2019-10-09 | Valiant Biopharma SDN BHD | Antimikrobielle fusionsverbindungen und verwendungen davon |
WO2015048901A1 (en) | 2013-10-02 | 2015-04-09 | Viventia Bio Inc. | Anti-epcam antibodies and methods of use |
US10583198B2 (en) | 2015-03-12 | 2020-03-10 | Viventia Bio Inc. | Dosing strategies for targeting EPCAM positive bladder cancer |
CN108513547A (zh) | 2015-03-12 | 2018-09-07 | 维文蒂亚生物公司 | 用于epcam阳性膀胱癌的治疗方法 |
CN111405911A (zh) | 2017-10-10 | 2020-07-10 | 梅迪塞纳医疗股份有限公司 | 用于治疗中枢神经系统(cns)肿瘤的il-4融合制剂 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2255843A1 (en) * | 1973-12-26 | 1975-07-25 | Chatenoud Gilles | Device for watering plants in window boxeseetc - has water container, wick, distributor and filler pipe |
GB2095083A (en) | 1981-03-20 | 1982-09-29 | Fah Ah Ngau | Automatic watering system for plants |
DE3525266A1 (de) * | 1985-07-16 | 1987-01-29 | Zlatko Rajmund Fers | Vorrichtung zum bewaessern von pflanzen und gestecken |
FR2646750A1 (fr) | 1989-05-09 | 1990-11-16 | Stroppa Mauro | Dispositif modulaire en kit a capacite variable a humidification capillaire permettant de transformer tout recipient quelconque en un bac a plantes a reserve d'eau |
US5376546A (en) | 1991-11-04 | 1994-12-27 | Xoma Corporation | Analogs of ribosome-inactivating proteins |
JPH08510642A (ja) | 1993-05-12 | 1996-11-12 | ゾマ コーポレイション | ゲロニンおよび抗体から成る免疫毒素 |
US5597569A (en) | 1993-10-25 | 1997-01-28 | Bristol-Myers Squibb Company | Bryodin 2 a ribosome-inactivating protein isolated from the plant Bryonia dioica |
US5535547A (en) * | 1995-09-15 | 1996-07-16 | Brunengo; P. John | Conduit and float gauge apparatus |
-
1998
- 1998-06-08 WO PCT/NL1998/000336 patent/WO1998055623A1/en active Application Filing
- 1998-06-08 CA CA2295189A patent/CA2295189C/en not_active Expired - Lifetime
- 1998-06-08 US US09/445,160 patent/US6680296B1/en not_active Expired - Lifetime
- 1998-06-08 AT AT98928659T patent/ATE527358T1/de not_active IP Right Cessation
- 1998-06-08 EP EP98928659A patent/EP0975762B1/de not_active Expired - Lifetime
- 1998-06-08 AU AU80408/98A patent/AU8040898A/en not_active Abandoned
-
2004
- 2004-01-16 US US10/758,902 patent/US7479552B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0975762B1 (de) | 2011-10-05 |
CA2295189C (en) | 2010-11-23 |
WO1998055623A1 (en) | 1998-12-10 |
CA2295189A1 (en) | 1998-12-10 |
AU8040898A (en) | 1998-12-21 |
US7479552B2 (en) | 2009-01-20 |
US6680296B1 (en) | 2004-01-20 |
EP0975762A1 (de) | 2000-02-02 |
US20040266994A1 (en) | 2004-12-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |