ATE525071T1 - Verbindngen zur hemmung der sap-bindung zur behandlung von osteoarthritis - Google Patents

Verbindngen zur hemmung der sap-bindung zur behandlung von osteoarthritis

Info

Publication number
ATE525071T1
ATE525071T1 AT04736527T AT04736527T ATE525071T1 AT E525071 T1 ATE525071 T1 AT E525071T1 AT 04736527 T AT04736527 T AT 04736527T AT 04736527 T AT04736527 T AT 04736527T AT E525071 T1 ATE525071 T1 AT E525071T1
Authority
AT
Austria
Prior art keywords
osteoarthritis
treatment
compounds
sap binding
inhibiting
Prior art date
Application number
AT04736527T
Other languages
English (en)
Inventor
Mark Pepys
Philip Hawkins
Original Assignee
Pentraxin Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pentraxin Therapeutics Ltd filed Critical Pentraxin Therapeutics Ltd
Application granted granted Critical
Publication of ATE525071T1 publication Critical patent/ATE525071T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401—Proline; Derivatives thereof, e.g. captopril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
AT04736527T 2003-06-10 2004-06-10 Verbindngen zur hemmung der sap-bindung zur behandlung von osteoarthritis ATE525071T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0313386.5A GB0313386D0 (en) 2003-06-10 2003-06-10 Treatment of disease
PCT/GB2004/002445 WO2004108131A1 (en) 2003-06-10 2004-06-10 Compounds inhibiting the binding of sap for treating osteoarthritis

Publications (1)

Publication Number Publication Date
ATE525071T1 true ATE525071T1 (de) 2011-10-15

Family

ID=27589813

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04736527T ATE525071T1 (de) 2003-06-10 2004-06-10 Verbindngen zur hemmung der sap-bindung zur behandlung von osteoarthritis

Country Status (9)

Country Link
US (1) US7659299B2 (de)
EP (1) EP1633345B1 (de)
JP (1) JP2006527250A (de)
AT (1) ATE525071T1 (de)
AU (1) AU2004244815B2 (de)
CA (1) CA2528706C (de)
ES (1) ES2373553T3 (de)
GB (2) GB0313386D0 (de)
WO (1) WO2004108131A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003013508A1 (en) 2001-08-08 2003-02-20 Pentraxin Therapeutics Limited Therapeutic agent for depletion of an unwanted protein population from plasma
US20100297074A1 (en) * 2002-12-23 2010-11-25 Richard Hans Gomer Wound healing compositions, systems, and methods
WO2014124334A2 (en) 2013-02-08 2014-08-14 Misfolding Diagnostics, Inc. Transthyretin antibodies and uses thereof
US9737505B2 (en) 2014-04-29 2017-08-22 Glaxosmithkline Intellectual Property Development Limited Prodrug of 1,1′-(1,6-dioxo-1,6-hexanediyl)bis-D-proline
GB201407506D0 (en) 2014-04-29 2014-06-11 Glaxosmithkline Ip Dev Ltd Novel compound

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62277352A (ja) * 1986-01-30 1987-12-02 Ono Pharmaceut Co Ltd 新規な６−ケト−プロスタグランジンｅ１誘導体、それらの製造方法およびそれらを有効成分として含有する細胞障害治療剤
US4895872A (en) * 1989-03-15 1990-01-23 Cetus Corporation Immunosupressive analogues and derivatives of succinylacetone
GB9317120D0 (en) * 1993-08-17 1993-09-29 Royal Postgrad Med School Human serum amyloid p component
US6172045B1 (en) 1994-12-07 2001-01-09 Neorx Corporation Cluster clearing agents
TR199902692T2 (xx) 1997-05-02 2000-07-21 Akzo Nobel N.V. Serin proteaz inhibit�rleri.
US6365570B1 (en) * 1997-10-10 2002-04-02 Universiteit Utrecht Pharmaceutical and diagnostic use of Serum Amyloid P component
DE69808017T2 (de) * 1997-10-31 2003-04-30 Hoffmann La Roche D-Prolinderivate
GB0119370D0 (en) * 2001-08-08 2001-10-03 Univ London Therapeutic agent
WO2003013508A1 (en) * 2001-08-08 2003-02-20 Pentraxin Therapeutics Limited Therapeutic agent for depletion of an unwanted protein population from plasma
US6903129B2 (en) * 2001-12-14 2005-06-07 Hoffman-La Roche Inc. D-proline prodrugs
GB0211136D0 (en) * 2002-05-15 2002-06-26 Univ London Treatment and prevention of tissue damage
WO2004099173A1 (en) * 2003-05-12 2004-11-18 Theracarb Inc. Multivalent inhibitors of serum amyloid p component

Also Published As

Publication number Publication date
AU2004244815A1 (en) 2004-12-16
EP1633345A1 (de) 2006-03-15
US20080249003A1 (en) 2008-10-09
CA2528706A1 (en) 2004-12-16
CA2528706C (en) 2012-10-30
GB0313386D0 (en) 2003-07-16
GB2420498A (en) 2006-05-31
GB0600229D0 (en) 2006-02-15
ES2373553T3 (es) 2012-02-06
EP1633345B1 (de) 2011-09-21
GB2420498B (en) 2007-11-28
JP2006527250A (ja) 2006-11-30
US7659299B2 (en) 2010-02-09
WO2004108131A1 (en) 2004-12-16
AU2004244815B2 (en) 2009-12-10

Similar Documents

Publication Publication Date Title
DE602004026891D1 (de) Tlr7-liganden zur behandlung von hepatitis c
ATE532518T1 (de) Dipeptidyl-peptidase-hemmer zur behandlung von diabetes
UA96565C2 (ru) Пиридильные ингибиторы хеджхоговской передачи сигнала
ATE453653T1 (de) Platinkomplexe zur behandlung von tumoren
DE60210093D1 (de) Beta-amino-tetrahydroimidazo(1,2-a)pyrazine und -tetrahydrotriazolo(4,3-a)pyrazine als dipeptidyl peptidase inhibitoren zur behandlung oder prevention von diabetes
EP1638950A4 (de) Cyclohexylglycinderivate als dipeptidylpeptidaseinhibitoren zur behandlung bzw. prevention von diabetes
ATE410430T1 (de) 2,3-dihydro-6-nitroimidazoä2,1- büoxazolverbindungen zur behandlung von tuberkulose
GEP20125511B (en) Mapk/erk kinase inhibitors
ATE376828T1 (de) Verwendung von rotigotin zur behandlung und prävention des parkinson-plus-syndroms
EA200970447A1 (ru) Соединения и композиции в качестве ингибиторов протеинкиназы
ATE458485T1 (de) Ubiquitin-ligase-hemmer und verwandte verfahren
DE602005026984D1 (de) Chinolin-derivate zur behandlung von latenter tuberkulose
DE50311898D1 (de) Fredericamycin-derivate als arzneimittel zur tumorbehandlung
RS51069B (sr) Upotreba oksikodona za tretiranje visceralnog bola
PL1654253T3 (pl) Podstawione pochodne 3-pirolidynoindolu
TW200509949A (en) Pharmaceutical compositions and methods relating to inhibiting fibrous adhesions using various agents
DE602006003094D1 (de) 4-phenyl-5-oxo-1,4,5,6,7,8-hexahydrochinolin-derivate zur behandlung von unfruchtbarkeit
ATE466841T1 (de) 1-phenethylpiperidinderivate und ihre verwendung als opioidrezeptor-liganden
DE602005016141D1 (de) S-mirtazapin zur behandlung von hitzewallungen
DE602006002608D1 (de) 4-phenyl-5-oxo-l,4,5,6,7,8-hexahydrochinolin-derivate als arzneimittel zur behandlung von unfruchtbarkeit
WO2004073615A8 (en) Deazaflavin compounds and methods of use thereof
ATE457727T1 (de) Kombination aus pyrimidylaminobenzamid- verbindungen und imatinib zur behandlung oder verhinderung proliferativer erkrankungen
ATE525071T1 (de) Verbindngen zur hemmung der sap-bindung zur behandlung von osteoarthritis
WO2005081972A3 (en) Maleiimide anti-tumor phosphatase inhibitors
TW200503666A (en) Treatment of type 1 diabetes with pde5 inhibitors

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties