ATE522507T1 - Montelukast in fester phase - Google Patents

Montelukast in fester phase

Info

Publication number
ATE522507T1
ATE522507T1 AT04765940T AT04765940T ATE522507T1 AT E522507 T1 ATE522507 T1 AT E522507T1 AT 04765940 T AT04765940 T AT 04765940T AT 04765940 T AT04765940 T AT 04765940T AT E522507 T1 ATE522507 T1 AT E522507T1
Authority
AT
Austria
Prior art keywords
montelukast
compound
fixed phase
formula
formulated
Prior art date
Application number
AT04765940T
Other languages
English (en)
Inventor
Arjanne Overeem
Den Heuvel Dennie Van
Original Assignee
Synhton B V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34520017&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE522507(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Synhton B V filed Critical Synhton B V
Application granted granted Critical
Publication of ATE522507T1 publication Critical patent/ATE522507T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Quinoline Compounds (AREA)
AT04765940T 2003-10-10 2004-10-08 Montelukast in fester phase ATE522507T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50995703P 2003-10-10 2003-10-10
PCT/EP2004/011430 WO2005040123A1 (en) 2003-10-10 2004-10-08 Solid-state montelukast

Publications (1)

Publication Number Publication Date
ATE522507T1 true ATE522507T1 (de) 2011-09-15

Family

ID=34520017

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04765940T ATE522507T1 (de) 2003-10-10 2004-10-08 Montelukast in fester phase

Country Status (12)

Country Link
US (1) US7553853B2 (de)
EP (1) EP1678139B1 (de)
JP (2) JP2007508271A (de)
AT (1) ATE522507T1 (de)
AU (1) AU2004283832B2 (de)
CA (1) CA2541994A1 (de)
ES (1) ES2371549T3 (de)
IL (1) IL174758A (de)
NO (1) NO20062098L (de)
PT (1) PT1678139E (de)
WO (1) WO2005040123A1 (de)
ZA (1) ZA200602837B (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050107612A1 (en) * 2002-12-30 2005-05-19 Dr. Reddy's Laboratories Limited Process for preparation of montelukast and its salts
EP1678139B1 (de) 2003-10-10 2011-08-31 Synhton B.V. Montelukast in fester phase
EP1709001A2 (de) * 2004-01-28 2006-10-11 Pliva Istrazivanje i Razvoj d.o.o. Feste formen von montelukastsäure
US20050187243A1 (en) * 2004-01-30 2005-08-25 Valerie Niddam-Hildesheim Montelukast free acid polymorphs
EP1760077A1 (de) * 2004-01-30 2007-03-07 Teva Pharmaceutical Industries Ltd. Polymorphe Formen vonMontelukast freie Säure
WO2005075427A2 (en) * 2004-01-30 2005-08-18 Teva Pharmaceutical Industries Ltd. Montelukast sodium polymorphs
BRPI0506610A (pt) 2004-02-03 2007-05-02 Chemagis Ltd montelucaste sódico amorfo, processo de preparação de montelucaste sódico amorfo, composição farmacêutica, método de tratamento utilizando a administração de montelucaste sódico amorfo, co-precipitado amorfo de montelucaste sódico e processo de preparação de co-precipitado amorfo de montelucaste sódico
MXPA06012220A (es) * 2004-04-21 2007-07-18 Teva Pharma Procesos para preparar sodio de montelukast.
US7501517B2 (en) * 2004-04-30 2009-03-10 Synthon Ip, Inc. Process for making montelukast and intermediates therefor
US7829716B2 (en) * 2004-04-30 2010-11-09 Synthon Pharmaceuticals, Inc. Process for making montelukast and intermediates therefor
US20090143590A1 (en) * 2004-07-19 2009-06-04 Matrix Laboratories Ltd. Process for the Preparation of Montelukast and its Salts
US9149472B2 (en) * 2004-08-31 2015-10-06 Jack William Schultz Controlled release compositions for treatment of cognitive, emotional and mental ailments and disorders
US20080214822A1 (en) * 2004-11-30 2008-09-04 Medichem, S.A. Process For the Preparation of a Leukotriene Antagonist
WO2006064269A2 (en) * 2004-12-17 2006-06-22 Cipla Limited Salts of leukotriene antagonist montelukast
US7812168B2 (en) * 2005-07-05 2010-10-12 Teva Pharmaceutical Industries Ltd. Purification of montelukast
AR057908A1 (es) * 2005-11-18 2007-12-26 Synthon Bv Proceso para preparar montelukast e intermediarios del mismo
EP1968943B1 (de) * 2005-12-13 2013-01-23 MSN Laboratories Limited Verbessertes verfahren zur herstellung von montelukast und dessen pharmazeutisch unbedenklichen salze
EP1803457A1 (de) * 2005-12-30 2007-07-04 Krka Tovarna Zdravil, D.D., Novo Mesto Pharmazeutische Zubereitung, welche Montelukast enthält
EP1976522B2 (de) * 2005-12-30 2019-07-03 KRKA, tovarna zdravil, d.d., Novo mesto Pharmazeutische zusammensetzung mit montelukast
WO2007092031A1 (en) * 2006-02-09 2007-08-16 Teva Pharmaceutical Industries Ltd. Stable pharmaceutical formulations of montelukast sodium
EP1996552A1 (de) * 2006-03-17 2008-12-03 Synthon B.V. Montelukast-amantadin-salz
EP1886998A1 (de) * 2006-08-09 2008-02-13 Esteve Quimica, S.A. Verfahren zur Reinigung von Montelukast und dessen Aminesalzen
SI22382A (sl) * 2006-10-26 2008-04-30 Krka, Tovarna Zdravil, D.D., Novo Mesto Nov postopek za pripravo montelukasta
WO2008062478A2 (en) * 2006-11-20 2008-05-29 Manne Satyanarayana Reddy Improved process for pure montelukast sodium through pure intermediates as well as novel amine salts
US20080188664A1 (en) * 2007-01-15 2008-08-07 Chemagis Ltd. Process for preparing montelukast sodium containing controlled levels of impurities
CN101909626A (zh) * 2007-10-25 2010-12-08 默克弗罗斯特加拿大有限公司 联合疗法
WO2009098271A1 (en) * 2008-02-06 2009-08-13 Farmaprojects, S.A. Process for the purification of montelukast by the preparation of acid addition salts and tert-amylamine salt
EP2276739A1 (de) * 2008-04-25 2011-01-26 Synthon B.V. Verfahren zur herstellung von montelukast-zwischenprodukten
EP2287154A1 (de) 2009-07-14 2011-02-23 KRKA, D.D., Novo Mesto Effiziente Synthese zur Herstellung von Montelukast
US8658208B2 (en) 2010-02-26 2014-02-25 Toray Industries, Inc. Coated solid preparation
WO2011121091A1 (en) 2010-03-31 2011-10-06 Krka, D.D., Novo Mesto Efficient synthesis for the preparation of montelukast and novel crystalline form of intermediates therein
US8471030B2 (en) 2010-12-06 2013-06-25 Orochem Technologies Inc. Purification of montelukast using simulated moving bed
JP6488003B2 (ja) 2014-04-25 2019-03-20 アールピー シーラー テクノロジーズ リミテッド ライアビリティ カンパニー 安定なモンテルカスト溶液
CN112789037A (zh) 2018-09-06 2021-05-11 创新药物筛选有限公司 用于治疗哮喘或帕金森病的方法和药物组合物
CN111307979A (zh) * 2020-03-14 2020-06-19 鲁南制药集团股份有限公司 一种孟鲁司特钠及其制剂的有关物质检测方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0480717B1 (de) 1990-10-12 1998-04-15 Merck Frosst Canada Inc. Ungesättigte Hydroxyalkylchinolinsäuren als Leukotrien-Antagonisten
EP0480716A1 (de) * 1990-10-12 1992-04-15 Merck Frosst Canada Inc. Gesättigte Hydroxyalkylchinolinsäuren zur Verwendung als Leukotrien-Antagonisten
US5856322A (en) * 1990-10-12 1999-01-05 Merck Frosst Canada, Inc. Unsaturated hydroxyalkylquinoline acids as leukotriene antagonists
US5565473A (en) 1990-10-12 1996-10-15 Merck Frosst Canada, Inc. Unsaturated hydroxyalkylquinoline acids as leukotriene antagonists
US5266568A (en) * 1990-10-12 1993-11-30 Merck Frosst Canada, Inc. Hydroxyalkylquinoline ether acids as leukotriene antagonists
US5270324A (en) * 1992-04-10 1993-12-14 Merck Frosst Canada, Inc. Fluorinated hydroxyalkylquinoline acids as leukotriene antagonists
TW448160B (en) 1993-12-28 2001-08-01 Merck & Co Inc Novel dicyclohexylamine salt and process for the preparation of leukotriene antagonists
GB9423511D0 (en) 1994-11-22 1995-01-11 Glaxo Wellcome Inc Compositions
US5585115A (en) * 1995-01-09 1996-12-17 Edward H. Mendell Co., Inc. Pharmaceutical excipient having improved compressability
US5523477A (en) * 1995-01-23 1996-06-04 Merck & Co., Inc. Process for the preparation of 1-(thiomethyl)-cyclopropaneacetic acid
US5869673A (en) * 1997-02-28 1999-02-09 Merck & Co., Inc. Process for 3-(2-(7-chloro-2-quinolinyl)ethenyl) - benzaldehyde
US6224907B1 (en) * 1998-03-06 2001-05-01 Alza Corporation Anti-asthma therapy
EA005116B1 (ru) * 2000-10-20 2004-10-28 Эли Лилли Энд Компани НОВАЯ КРИСТАЛЛИЧЕСКАЯ ФОРМА ГИДРОХЛОРИДА 6-ГИДРОКСИ-3-(4-[2-(ПИПЕРИДИН-1-ИЛ)ЭТОКСИ]ФЕНОКСИ)-2-(4-МЕТОКСИФЕНИЛ)БЕНЗО[b]ТИОФЕНА
CN1420113A (zh) * 2001-11-16 2003-05-28 北京上地新世纪生物医药研究所 孟鲁司特钠的制备方法及其制备中间体
CN1171873C (zh) * 2001-12-26 2004-10-20 北京上地新世纪生物医药研究所 一种孟鲁司特钠的制备方法及其制备中间体
AU2003209043A1 (en) 2002-02-07 2003-09-02 Dr. Reddy's Laboratories Ltd. Novel anhydrous amorphous forms of montelukast sodium salt
US20050107612A1 (en) * 2002-12-30 2005-05-19 Dr. Reddy's Laboratories Limited Process for preparation of montelukast and its salts
US20040265375A1 (en) * 2003-04-16 2004-12-30 Platteeuw Johannes J. Orally disintegrating tablets
US8450491B2 (en) 2003-06-06 2013-05-28 Morepen Laboratories Limited Method for the preparation of montelukast acid and sodium salt thereof in amorphous form
EP1678139B1 (de) 2003-10-10 2011-08-31 Synhton B.V. Montelukast in fester phase
US20050187243A1 (en) * 2004-01-30 2005-08-25 Valerie Niddam-Hildesheim Montelukast free acid polymorphs
US7189853B2 (en) * 2004-04-15 2007-03-13 Dr. Reddy's Laboratories Limited Process for the preparation of [R-(E)-1-[[[1-[3-[2-[7-chloro-2-quinolinyl]ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic acid (Montelukast) and its pharmaceutically acceptable salts
US7829716B2 (en) * 2004-04-30 2010-11-09 Synthon Pharmaceuticals, Inc. Process for making montelukast and intermediates therefor
US7501517B2 (en) * 2004-04-30 2009-03-10 Synthon Ip, Inc. Process for making montelukast and intermediates therefor

Also Published As

Publication number Publication date
NO20062098L (no) 2006-05-10
EP1678139A1 (de) 2006-07-12
US7553853B2 (en) 2009-06-30
AU2004283832A1 (en) 2005-05-06
US20050107426A1 (en) 2005-05-19
WO2005040123A1 (en) 2005-05-06
ES2371549T3 (es) 2012-01-05
IL174758A (en) 2012-09-24
CA2541994A1 (en) 2005-05-06
PT1678139E (pt) 2011-11-28
JP2007508271A (ja) 2007-04-05
JP2012072149A (ja) 2012-04-12
IL174758A0 (en) 2006-08-20
AU2004283832B2 (en) 2011-04-07
ZA200602837B (en) 2007-09-26
EP1678139B1 (de) 2011-08-31

Similar Documents

Publication Publication Date Title
ATE522507T1 (de) Montelukast in fester phase
TW200616976A (en) Pyrimidine derivatives
LUC00155I1 (de)
TW200738241A (en) Pyridazine derivatives
TW200626558A (en) Indazolone derivatives
WO2006010546A3 (en) Aryl-pyridine derivatives as 11-beta-hsd1 inhibitors
ATE327977T1 (de) Tetrahydrochinolin-derivate als crth2 antagonisten
MX2010005824A (es) Derivados de aminotiazol.
TW200740764A (en) Pyrazolone derivatives
EA200200938A1 (ru) Фармацевтические композиции, содержащие производные азетидина, новые производные азетидина и их получение
MXPA05008172A (es) Derivados de malonamida como inhibidores gamma-secretasa.
BR0317749A (pt) Composto, composição farmacêutica, e, uso de um composto
RS52823B (en) NEW UNITS USEFUL FOR TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES
TW200616958A (en) New alkyl-pyridines as 11-beta inhibitors for diabetes
ATE297910T1 (de) Retinoid x rezeptormodulatoren
ME01395B (de) Verfahren zur Herstellung von (1S)-4,5-Dimethoxy-1-(methylaminomethyl)-benzocyclobutan und deren Säureadditionssalze, sowie ihre Verwendung für die Synthese von Ivabradin und deren Säureadditionssalze von pharmazeutischen verträglichen Säure
EP1340755A4 (de) Mittel mit wirkung gegen helicobacter
MXPA06000921A (es) Derivados de benzamidazoles como inhibidores de mek.
DE602006021539D1 (en) Morpholine als 5ht2c-agonisten
WO2005120516A3 (en) Hiv integrase inhibitors
NO20085317L (no) Imidazoazepinonforbindelser
IS7482A (is) Fjölhringa efnasambönd sem sterk alfa2-adrenóviðtakamótlyf
MX2009003169A (es) Derivados de sulfonamida.
HRP20060023A2 (en) Use of bicyclo[2.2.1]heptane derivatives for the preparation of neuroprotective pharmaceutical compositions
MY135646A (en) Indolyl derivatives

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties