ATE514786T1 - Biokatalytische synthese von shikiminsäure - Google Patents

Biokatalytische synthese von shikiminsäure

Info

Publication number
ATE514786T1
ATE514786T1 AT99956926T AT99956926T ATE514786T1 AT E514786 T1 ATE514786 T1 AT E514786T1 AT 99956926 T AT99956926 T AT 99956926T AT 99956926 T AT99956926 T AT 99956926T AT E514786 T1 ATE514786 T1 AT E514786T1
Authority
AT
Austria
Prior art keywords
acid
shikiminic
biocatalytic synthesis
synthesis
carbon source
Prior art date
Application number
AT99956926T
Other languages
German (de)
English (en)
Inventor
John Frost
Karen Frost
David Knop
Original Assignee
Univ Michigan State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Michigan State filed Critical Univ Michigan State
Application granted granted Critical
Publication of ATE514786T1 publication Critical patent/ATE514786T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/03—Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
    • C12Y402/03004—3-Dehydroquinate synthase (4.2.3.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185—Escherichia
    • C12R2001/19—Escherichia coli
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/848—Escherichia
    • Y10S435/849—Escherichia coli
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/94—Saccharomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT99956926T 1999-01-29 1999-11-04 Biokatalytische synthese von shikiminsäure ATE514786T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/240,440 US6613552B1 (en) 1999-01-29 1999-01-29 Biocatalytic synthesis of shikimic acid
PCT/US1999/026112 WO2000044923A1 (en) 1999-01-29 1999-11-04 Biocatalytic synthesis of shikimic acid

Publications (1)

Publication Number Publication Date
ATE514786T1 true ATE514786T1 (de) 2011-07-15

Family

ID=22906534

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99956926T ATE514786T1 (de) 1999-01-29 1999-11-04 Biokatalytische synthese von shikiminsäure

Country Status (7)

Country Link
US (2) US6613552B1 (enExample)
EP (1) EP1151126B1 (enExample)
JP (1) JP4669613B2 (enExample)
AT (1) ATE514786T1 (enExample)
AU (1) AU1342700A (enExample)
ES (1) ES2365205T3 (enExample)
WO (1) WO2000044923A1 (enExample)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002029078A2 (en) * 1999-01-29 2002-04-11 Board Of Trustees Operating Michigan State University Biocatalytic synthesis of shikimic acid
US6600077B1 (en) * 1999-01-29 2003-07-29 Board Of Trustees Operating Michigan State University Biocatalytic synthesis of quinic acid and conversion to hydroquinone
JP2004502457A (ja) * 2000-07-07 2004-01-29 ビーエーエスエフ　アクチェンゲゼルシャフト 除草剤標的としてのデヒドロキナ酸デヒドラターゼ／シキミ酸デヒドロゲナーゼ
DE10107002A1 (de) 2001-02-15 2002-08-29 Consortium Elektrochem Ind Verfahren zur fermentativen Herstellung von O-Acetyl-L-Serin
US6794164B2 (en) * 2002-01-07 2004-09-21 Novozymes Biopharma Ab Process for the isolation of polyhydroxy cyclic carboxylic acids
EP1546304B1 (en) * 2002-10-04 2013-05-08 Danisco US Inc. Improved production of bacterial strains
AU2003287028B2 (en) 2002-10-04 2008-09-04 E.I. Du Pont De Nemours And Company Process for the biological production of 1,3-propanediol with high yield
US7790431B2 (en) * 2003-09-24 2010-09-07 Board Of Trustees Operating Michigan State University Methods and materials for the production of shikimic acid
ES2909600T3 (es) 2005-06-07 2022-05-09 Dsm Nutritional Products Ag Microorganismos eucarióticos para producir lípidos y antioxidantes
US20070134282A1 (en) * 2005-12-09 2007-06-14 Stephen F. Austin State University Methods for inhibiting fungal pathogen infestation and propogation
US20070149805A1 (en) * 2005-12-23 2007-06-28 Stephen F. Austin State University Method for the extraction and purification of shikimic acid
US20070161818A1 (en) * 2006-01-06 2007-07-12 Shiyou Li Processes for the extraction and purification of shikimic acid and the products of such processes
US7977077B2 (en) 2006-01-30 2011-07-12 Board Of Trustees Of Michigan State University Synthesis of intermediates of oseltamivir carboxylates
US9023616B2 (en) 2006-08-01 2015-05-05 Dsm Nutritional Products Ag Oil producing microbes and method of modification thereof
WO2008027570A2 (en) * 2006-08-30 2008-03-06 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Method of isolating shikimic acid from a plant
US8435769B2 (en) * 2007-04-13 2013-05-07 Monsanto Technology Llc Use of glyphosate to produce shikimic acid in microorganisms
US8344178B2 (en) * 2007-10-16 2013-01-01 Monsanto Technology Llc Processes for producing and recovering shikimic acid
WO2010077806A1 (en) * 2008-12-15 2010-07-08 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways
CN102333878B (zh) * 2008-12-22 2015-08-26 绿光生物科学公司 用于制造化合物的组合物和方法
KR20130071433A (ko) 2010-05-07 2013-06-28 그린라이트 바이오사이언시스, 아이엔씨. 효소의 재배치를 통한 대사 경로에서의 흐름의 제어 방법
US8916358B2 (en) 2010-08-31 2014-12-23 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways through protease manipulation
CN104093848A (zh) 2011-09-09 2014-10-08 绿光生物科学公司 碳青霉烯(carbapenem)的无细胞制备
CA2862051A1 (en) * 2012-01-30 2013-08-08 Myriant Corporation Production of muconic acid from genetically engineered microorganisms
JP6322576B2 (ja) 2012-07-03 2018-05-09 花王株式会社 有用微生物および目的物質の製造方法
AU2013364025A1 (en) 2012-12-21 2015-07-23 Greenlight Biosciences, Inc. Cell-free system for converting methane into fuel, pyruvate or isobutanol
US20150247174A1 (en) * 2012-12-28 2015-09-03 Anhui Huaheng Bioengineering Co., Ltd, Engineering bacteria for producing dl-alanine and method for producing dl-alanine by using engineering bacteria
AU2014229307B2 (en) 2013-03-13 2017-08-31 Dsm Nutritional Products Ag Engineering microorganisms
WO2015021058A2 (en) 2013-08-05 2015-02-12 Greenlight Biosciences, Inc. Engineered proteins with a protease cleavage site
KR102105532B1 (ko) * 2013-10-17 2020-04-29 (주)아모레퍼시픽 만능 줄기세포의 유도 방법 및 상기 방법에 의해 제조된 만능줄기세포
US10208313B2 (en) 2014-08-21 2019-02-19 Research Institute Of Innovative Technology For The Earth Coryneform bacterium transformant and process for producing organic compound using the same
RU2017137788A (ru) 2015-03-30 2019-04-30 Гринлайт Байосайенсис, Инк. Бесклеточное получение рибонуклеиновой кислоты
WO2017151811A1 (en) 2016-03-02 2017-09-08 Myriant Corporation Improved muconic acid production from genetically engineered microorganisms
SG11201808721YA (en) 2016-04-06 2018-11-29 Greenlight Biosciences Inc Cell-free production of ribonucleic acid
WO2019075167A1 (en) 2017-10-11 2019-04-18 Greenlight Biosciences, Inc. METHODS AND COMPOSITIONS FOR THE PRODUCTION OF NUCLEOSIDE TRIPHOSPHATE AND RIBONUCLEIC ACID
EP3842045A4 (en) * 2018-08-23 2021-10-20 Sumitomo Bakelite Co.Ltd. MEDICINAL PRODUCTS, ANTI-CANCER PRODUCTS, MEDICAL INTERMEDIATE AND PROCESS FOR THE PREPARATION OF A CYCLIC CARBONIC ACID COMPOUND OR A DERIVATIVE THEREOF
KR102676309B1 (ko) * 2019-11-22 2024-06-19 (주)에스티알바이오텍 시킴산 생산용 미생물 및 이를 이용한 시킴산 생산 방법

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US5168056A (en) 1991-02-08 1992-12-01 Purdue Research Foundation Enhanced production of common aromatic pathway compounds
US5798236A (en) * 1992-09-30 1998-08-25 Genencor International, Inc. Synthesis of quinic acid from glucose
CA2148482C (en) 1992-12-21 2006-10-31 John W. Frost Deblocking the common pathway of aromatic amino acid synthesis
DK0782621T3 (da) 1994-09-16 2006-07-03 Texas A & M Univ Sys Mikroorganismer samt fremgangsmåde til overproduktion af DAHP ved hjælp af klonet PPS-gen
DK0827542T3 (da) 1995-05-05 2008-08-18 Genencor Int Anvendelse af glucose-transport-mutanter til fremstilling af forbindelser fra den aromatiske pathway
EP1038968A3 (en) * 1999-03-25 2002-10-02 Ajinomoto Co., Inc. Method for producing shikimic acid

Also Published As

Publication number Publication date
ES2365205T3 (es) 2011-09-26
JP4669613B2 (ja) 2011-04-13
EP1151126A4 (en) 2002-04-10
US6472169B1 (en) 2002-10-29
AU1342700A (en) 2000-08-18
US6613552B1 (en) 2003-09-02
WO2000044923A1 (en) 2000-08-03
JP2002535008A (ja) 2002-10-22
EP1151126A1 (en) 2001-11-07
EP1151126B1 (en) 2011-06-29

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