ATE511518T1 - Verfahren zum stabilisieren des gewebefaktors - Google Patents
Verfahren zum stabilisieren des gewebefaktorsInfo
- Publication number
- ATE511518T1 ATE511518T1 AT08005295T AT08005295T ATE511518T1 AT E511518 T1 ATE511518 T1 AT E511518T1 AT 08005295 T AT08005295 T AT 08005295T AT 08005295 T AT08005295 T AT 08005295T AT E511518 T1 ATE511518 T1 AT E511518T1
- Authority
- AT
- Austria
- Prior art keywords
- tissue factor
- stabilizing
- stabilizing tissue
- nonionic surfactant
- reagent
- Prior art date
Links
- 102000002262 Thromboplastin Human genes 0.000 title abstract 4
- 108010000499 Thromboplastin Proteins 0.000 title abstract 4
- 230000000087 stabilizing effect Effects 0.000 title abstract 3
- 239000002736 nonionic surfactant Substances 0.000 abstract 2
- 206010053567 Coagulopathies Diseases 0.000 abstract 1
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 230000035602 clotting Effects 0.000 abstract 1
- 150000002815 nickel Chemical class 0.000 abstract 1
- 229910001453 nickel ion Inorganic materials 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New breeds of animals
- A01K67/033—Rearing or breeding invertebrates; New breeds of invertebrates
- A01K67/0333—Genetically modified invertebrates, e.g. transgenic, polyploid
- A01K67/0337—Genetically modified Arthropods
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
- A01K2217/052—Animals comprising random inserted nucleic acids (transgenic) inducing gain of function
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/70—Invertebrates
- A01K2227/706—Insects, e.g. Drosophila melanogaster, medfly
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/01—Animal expressing industrially exogenous proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2525—Stabilizing or preserving
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Environmental Sciences (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Toxicology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007085578A JP4829828B2 (ja) | 2007-03-28 | 2007-03-28 | 血液凝固測定用試薬及び組織因子安定化方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE511518T1 true ATE511518T1 (de) | 2011-06-15 |
Family
ID=39472681
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT08005295T ATE511518T1 (de) | 2007-03-28 | 2008-03-20 | Verfahren zum stabilisieren des gewebefaktors |
Country Status (4)
Country | Link |
---|---|
US (1) | US7867771B2 (de) |
EP (1) | EP1975622B1 (de) |
JP (1) | JP4829828B2 (de) |
AT (1) | ATE511518T1 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2040073A1 (de) | 2007-09-20 | 2009-03-25 | Iline Microsystems, S.L. | Mikrofluidische Vorrichtung und Verfahren zur Flüssigkeitsgerinnungs-Zeitbestimmung |
CN102608337B (zh) * | 2011-04-22 | 2014-05-14 | 武汉塞力斯生物技术有限公司 | 凝血酶原时间测定试剂盒及其制备方法 |
JP6595247B2 (ja) | 2015-07-30 | 2019-10-23 | シスメックス株式会社 | 凝固時間の測定方法およびその装置、凝固時間測定用試薬ならびに試薬キット |
CN105368916B (zh) * | 2015-11-12 | 2019-11-22 | 武汉景川诊断技术股份有限公司 | 一种凝血酶原时间测定试剂盒及其制备方法 |
CN105368915B (zh) * | 2015-11-12 | 2019-03-08 | 武汉中太生物技术有限公司 | 凝血酶原时间测定试剂盒及其制备方法 |
JP6652873B2 (ja) | 2016-03-30 | 2020-02-26 | シスメックス株式会社 | プロトロンビン時間測定用試薬、その製造方法およびプロトロンビン時間の測定方法 |
WO2020067171A1 (ja) | 2018-09-25 | 2020-04-02 | 積水メディカル株式会社 | 血液凝固時間測定方法 |
CN110412001B (zh) * | 2019-08-01 | 2022-02-11 | 武汉塞力斯生物技术有限公司 | 一种动态监测凝血酶生成能力的试剂盒 |
JPWO2022145475A1 (de) * | 2020-12-28 | 2022-07-07 | ||
CN115508569A (zh) * | 2022-09-15 | 2022-12-23 | 上海太阳生物技术有限公司 | 蛋白s试剂及检测试剂盒 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5017556A (en) * | 1986-11-04 | 1991-05-21 | Genentech, Inc. | Treatment of bleeding disorders using lipid-free tissue factor protein |
JP3095608B2 (ja) * | 1993-03-30 | 2000-10-10 | 株式会社トクヤマ | 血液凝固時間測定乾燥試薬 |
DE19749259A1 (de) * | 1997-11-07 | 1999-05-12 | Dade Behring Marburg Gmbh | Verfahren zur Herstellung von funktionalem rekombinantem Gewebsfaktor |
JP4039722B2 (ja) * | 1997-12-01 | 2008-01-30 | シスメックス株式会社 | 複合因子測定試薬 |
US6733985B1 (en) * | 1999-05-19 | 2004-05-11 | International Technidyne Corporation | Preparation of stable liquid and dried synthetic prothrombin time reagents |
DE19937218A1 (de) * | 1999-08-06 | 2001-02-08 | Aventis Behring Gmbh | Verfahren zur Reindarstellung der den Blutgerinnungsfaktor VII aktivierenden Protease, ihres Proenzyms oder eines Gemisches beider Proteine mittels Affinitätschromatographie |
JP4526152B2 (ja) * | 2000-03-08 | 2010-08-18 | シスメックス株式会社 | プロトロンビン時間測定試薬 |
JP2002293861A (ja) | 2001-04-02 | 2002-10-09 | Yokohama Rubber Co Ltd:The | 硬化性化合物、該化合物を含有する硬化性樹脂組成物および硬化材の易解体方法 |
GB0202633D0 (en) * | 2002-02-05 | 2002-03-20 | Delta Biotechnology Ltd | Stabilization of protein preparations |
WO2004082708A2 (en) | 2003-03-18 | 2004-09-30 | Novo Nordisk Health Care Ag | Liquid, aqueous, pharmaceutical compositions of factor vii polypeptides |
US20050202509A1 (en) * | 2003-11-28 | 2005-09-15 | Sysmex Corporation | Reagent for measuring clotting time and method for measuring clotting time |
JP2008530208A (ja) * | 2005-02-16 | 2008-08-07 | ザ・ボード・オブ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・イリノイ | 万能前凝固薬 |
US20070015689A1 (en) * | 2005-06-23 | 2007-01-18 | Alza Corporation | Complexation of metal ions with polypeptides |
JP5073270B2 (ja) | 2006-11-14 | 2012-11-14 | シスメックス株式会社 | 凝固検査用試薬及びその製造方法 |
-
2007
- 2007-03-28 JP JP2007085578A patent/JP4829828B2/ja active Active
-
2008
- 2008-03-20 AT AT08005295T patent/ATE511518T1/de not_active IP Right Cessation
- 2008-03-20 EP EP08005295A patent/EP1975622B1/de active Active
- 2008-03-28 US US12/057,812 patent/US7867771B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
JP2008241621A (ja) | 2008-10-09 |
EP1975622A1 (de) | 2008-10-01 |
US20080241941A1 (en) | 2008-10-02 |
EP1975622B1 (de) | 2011-06-01 |
JP4829828B2 (ja) | 2011-12-07 |
US7867771B2 (en) | 2011-01-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |