ATE508752T1 - Deletionsmutante des dph2-gens und verwendungen davon - Google Patents

Deletionsmutante des dph2-gens und verwendungen davon

Info

Publication number
ATE508752T1
ATE508752T1 AT07720003T AT07720003T ATE508752T1 AT E508752 T1 ATE508752 T1 AT E508752T1 AT 07720003 T AT07720003 T AT 07720003T AT 07720003 T AT07720003 T AT 07720003T AT E508752 T1 ATE508752 T1 AT E508752T1
Authority
AT
Austria
Prior art keywords
deletion mutant
proteins
dph2
dph2 gene
gene
Prior art date
Application number
AT07720003T
Other languages
English (en)
Inventor
Manuel Caruso
Vincent Roy
Original Assignee
Manuel Caruso
Vincent Roy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Manuel Caruso, Vincent Roy filed Critical Manuel Caruso
Application granted granted Critical
Publication of ATE508752T1 publication Critical patent/ATE508752T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Enzymes And Modification Thereof (AREA)
AT07720003T 2006-06-16 2007-06-18 Deletionsmutante des dph2-gens und verwendungen davon ATE508752T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81404906P 2006-06-16 2006-06-16
PCT/CA2007/001087 WO2007143858A1 (en) 2006-06-16 2007-06-18 Dph2 gene deletion mutant and uses thereof

Publications (1)

Publication Number Publication Date
ATE508752T1 true ATE508752T1 (de) 2011-05-15

Family

ID=38831380

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07720003T ATE508752T1 (de) 2006-06-16 2007-06-18 Deletionsmutante des dph2-gens und verwendungen davon

Country Status (5)

Country Link
US (1) US8283166B2 (de)
EP (1) EP2038415B1 (de)
AT (1) ATE508752T1 (de)
CA (1) CA2655565A1 (de)
WO (1) WO2007143858A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITUB20152371A1 (it) * 2015-07-21 2017-01-21 Univ Degli Studi Di Torino Procedimento per indurre resistenza alla tossina difterica in cellule umane, relativi prodotti ed usi
JP6829761B2 (ja) * 2016-09-29 2021-02-10 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 遺伝子編集モジュールおよび遺伝子送達アプローチを解析および最適化するための方法
US11674950B2 (en) 2017-10-31 2023-06-13 Dana-Farber Cancer Institute, Inc. Methods determining and treating cellular resistance to ADP-rtbosylating toxin

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1071334A4 (de) 1998-04-17 2004-03-10 Whitehead Biomedical Inst Verfahren für effiziente und hochselektive bekämpfung von mikroorganismen
US20020177614A1 (en) 2001-03-23 2002-11-28 Merril Carl R. Methods for treating nuerodegenerative diseases including alzheimer's
US20030180756A1 (en) 2002-03-21 2003-09-25 Yang Shi Compositions and methods for suppressing eukaryotic gene expression
AU2003228466A1 (en) 2002-04-08 2003-10-27 The Johns Hopkins University Packaging cell line for diphtheria toxin expressing non-replicating adenovirus

Also Published As

Publication number Publication date
EP2038415B1 (de) 2011-05-11
US8283166B2 (en) 2012-10-09
US20090274670A1 (en) 2009-11-05
EP2038415A4 (de) 2009-10-14
WO2007143858A1 (en) 2007-12-21
CA2655565A1 (en) 2007-12-21
EP2038415A1 (de) 2009-03-25

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