ATE490462T1 - Verfahren zum anreichern von subpopulationen seltener zellen aus dem blut - Google Patents

Verfahren zum anreichern von subpopulationen seltener zellen aus dem blut

Info

Publication number
ATE490462T1
ATE490462T1 AT06849750T AT06849750T ATE490462T1 AT E490462 T1 ATE490462 T1 AT E490462T1 AT 06849750 T AT06849750 T AT 06849750T AT 06849750 T AT06849750 T AT 06849750T AT E490462 T1 ATE490462 T1 AT E490462T1
Authority
AT
Austria
Prior art keywords
blood
glycophorin
erythrocytes
epithelial cells
rare cells
Prior art date
Application number
AT06849750T
Other languages
English (en)
Inventor
Sarah Olken
Steven Bogen
Seshi Sompuram
Original Assignee
Medical Discovery Partners Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medical Discovery Partners Llc filed Critical Medical Discovery Partners Llc
Application granted granted Critical
Publication of ATE490462T1 publication Critical patent/ATE490462T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081—Purging biological preparations of unwanted cells
    • C12N5/0087—Purging against subsets of blood cells, e.g. purging alloreactive T cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Physiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT06849750T 2005-04-08 2006-04-04 Verfahren zum anreichern von subpopulationen seltener zellen aus dem blut ATE490462T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66938805P 2005-04-08 2005-04-08
PCT/US2006/012595 WO2007092028A2 (en) 2005-04-08 2006-04-04 Method for enriching rare cell subpopulations from blood

Publications (1)

Publication Number Publication Date
ATE490462T1 true ATE490462T1 (de) 2010-12-15

Family

ID=38345583

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06849750T ATE490462T1 (de) 2005-04-08 2006-04-04 Verfahren zum anreichern von subpopulationen seltener zellen aus dem blut

Country Status (5)

Country Link
US (1) US8263404B2 (de)
EP (1) EP1871870B1 (de)
AT (1) ATE490462T1 (de)
DE (1) DE602006018595D1 (de)
WO (1) WO2007092028A2 (de)

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WO2011063416A2 (en) * 2009-11-23 2011-05-26 The General Hospital Corporation Microfluidic devices for the capture of biological sample components
FR2963108B1 (fr) * 2010-07-21 2017-06-23 Diagast Procede magnetique d'immunodiagnostic et kit pour la mise en evidence de complexe anticorps/antigene de groupe/phenotype sanguin
CN103298546B (zh) * 2010-11-11 2015-06-24 瑞尔赛特股份有限公司 用于细胞过滤的方法和系统
WO2012068243A2 (en) * 2010-11-16 2012-05-24 Ingeneron, Inc. Methods for obtaining target cells
JP6342811B2 (ja) 2011-12-06 2018-06-13 ユニヴェルシテ リブル ドゥ ブリュッセル 赤血球上に存在する抗原または赤血球上に存在する抗原に結合する抗体を分析するための方法及び装置
CN103116215A (zh) * 2013-01-18 2013-05-22 王亚东 基于硝酸纤维素膜的脱落细胞学检查的新型细胞载片构件
KR102065112B1 (ko) 2013-02-28 2020-01-10 삼성전자주식회사 높은 항원 선택성을 갖는 항체의 스크리닝 방법
CA2942831A1 (en) 2013-03-15 2014-09-18 The Trustees Of Princeton University Methods and devices for high throughput purification
CN110186835B (zh) 2013-03-15 2022-05-31 Gpb科学有限公司 颗粒的片上微流体处理
US20150064153A1 (en) 2013-03-15 2015-03-05 The Trustees Of Princeton University High efficiency microfluidic purification of stem cells to improve transplants
GB201306810D0 (en) 2013-04-15 2013-05-29 Cells4Life Group Llp Methods of cell separation
US10976232B2 (en) 2015-08-24 2021-04-13 Gpb Scientific, Inc. Methods and devices for multi-step cell purification and concentration
CN107418871A (zh) * 2016-05-24 2017-12-01 北京百泰克生物技术有限公司 一种用于富集循环肿瘤细胞的自动化仪器的制作方法
JP6779483B2 (ja) 2016-09-29 2020-11-04 住友ゴム工業株式会社 医療用検査装置及び細胞検査方法
EP3675876A4 (de) 2017-09-01 2021-06-02 GPB Scientific, Inc. Verfahren zur herstellung therapeutisch aktiver zellen unter verwendung von mikrofluidik
CN109507427B (zh) * 2017-09-14 2022-05-31 上海白泽医学检验所有限公司 一种基于高亲和力cd45兔单抗的循环肿瘤细胞高效富集方法及其应用
JP7109719B2 (ja) * 2018-02-14 2022-08-01 住友ゴム工業株式会社 特定細胞捕捉方法
JP7158671B2 (ja) 2018-02-14 2022-10-24 住友ゴム工業株式会社 特定細胞捕捉方法
US11614440B2 (en) 2019-01-24 2023-03-28 Sumitomo Rubber Industries, Ltd. Specific cell fractionating and capturing methods

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US4097237A (en) 1977-03-04 1978-06-27 Technicon Instruments Corporation Determination of cells in blood
US4181609A (en) 1977-12-20 1980-01-01 Levine Robert A Blood constituents testing method
US4752582A (en) 1982-12-17 1988-06-21 The United States Of America As Represented By The United States Department Of Energy Monoclonal antibodies to human glycophorin A and cell lines for the production thereof
DE3422249A1 (de) 1984-06-15 1985-12-19 Pfeifer & Langen, 5000 Köln Wasserloesliches eisendextran und verfahren zu seiner herstellung
US4675286A (en) 1985-01-28 1987-06-23 Aspen Diagnostics, Inc. Fetal cell separation and testing
US4940668A (en) 1985-11-01 1990-07-10 Becton Dickinson And Company Method for increasing agglutination of groups of cells to produce improved cell layer interface in centrifuged blood sample
US4752563A (en) 1985-11-19 1988-06-21 Coulter Corporation Monoclonal antibody for recovery of leukocytes in human peripheral blood and method of recovery employing said monoclonal antibody
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ATE366801T1 (de) * 2002-09-27 2007-08-15 Bioe Inc Zusammensetzungen und verfahren zur trennung von zellen

Also Published As

Publication number Publication date
WO2007092028A2 (en) 2007-08-16
EP1871870A2 (de) 2008-01-02
US8263404B2 (en) 2012-09-11
WO2007092028A3 (en) 2007-11-22
EP1871870B1 (de) 2010-12-01
DE602006018595D1 (de) 2011-01-13
EP1871870A4 (de) 2009-03-25
US20090081632A1 (en) 2009-03-26

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