DE602006018595D1 - Verfahren zum anreichern von subpopulationen seltener zellen aus dem blut - Google Patents

Verfahren zum anreichern von subpopulationen seltener zellen aus dem blut

Info

Publication number
DE602006018595D1
DE602006018595D1 DE602006018595T DE602006018595T DE602006018595D1 DE 602006018595 D1 DE602006018595 D1 DE 602006018595D1 DE 602006018595 T DE602006018595 T DE 602006018595T DE 602006018595 T DE602006018595 T DE 602006018595T DE 602006018595 D1 DE602006018595 D1 DE 602006018595D1
Authority
DE
Germany
Prior art keywords
blood
glycophorin
erythrocytes
epithelial cells
subpopulations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006018595T
Other languages
English (en)
Inventor
Sarah K Olken
Steven A Bogen
Seshi R Sompuram
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boston Cell Standards LLC
Original Assignee
Medical Discovery Partners LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medical Discovery Partners LLC filed Critical Medical Discovery Partners LLC
Publication of DE602006018595D1 publication Critical patent/DE602006018595D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081Purging biological preparations of unwanted cells
    • C12N5/0087Purging against subsets of blood cells, e.g. purging alloreactive T cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Physiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE602006018595T 2005-04-08 2006-04-04 Verfahren zum anreichern von subpopulationen seltener zellen aus dem blut Active DE602006018595D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66938805P 2005-04-08 2005-04-08
PCT/US2006/012595 WO2007092028A2 (en) 2005-04-08 2006-04-04 Method for enriching rare cell subpopulations from blood

Publications (1)

Publication Number Publication Date
DE602006018595D1 true DE602006018595D1 (de) 2011-01-13

Family

ID=38345583

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006018595T Active DE602006018595D1 (de) 2005-04-08 2006-04-04 Verfahren zum anreichern von subpopulationen seltener zellen aus dem blut

Country Status (5)

Country Link
US (1) US8263404B2 (de)
EP (1) EP1871870B1 (de)
AT (1) ATE490462T1 (de)
DE (1) DE602006018595D1 (de)
WO (1) WO2007092028A2 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9034658B2 (en) * 2009-11-23 2015-05-19 The General Hospital Corporation Microfluidic devices for the capture of biological sample components
FR2963108B1 (fr) * 2010-07-21 2017-06-23 Diagast Procede magnetique d'immunodiagnostic et kit pour la mise en evidence de complexe anticorps/antigene de groupe/phenotype sanguin
WO2012065185A2 (en) * 2010-11-11 2012-05-18 Rarecyte, Inc. Method and system for cell filtration
WO2012068243A2 (en) * 2010-11-16 2012-05-24 Ingeneron, Inc. Methods for obtaining target cells
CN104081209B (zh) * 2011-12-06 2016-10-19 布鲁塞尔大学 测定红细胞上存在的抗原或结合至红细胞上存在的抗原的抗体的方法和设备
CN103116215A (zh) * 2013-01-18 2013-05-22 王亚东 基于硝酸纤维素膜的脱落细胞学检查的新型细胞载片构件
KR102065112B1 (ko) 2013-02-28 2020-01-10 삼성전자주식회사 높은 항원 선택성을 갖는 항체의 스크리닝 방법
US10324011B2 (en) 2013-03-15 2019-06-18 The Trustees Of Princeton University Methods and devices for high throughput purification
US20150064153A1 (en) 2013-03-15 2015-03-05 The Trustees Of Princeton University High efficiency microfluidic purification of stem cells to improve transplants
WO2014145152A2 (en) 2013-03-15 2014-09-18 Gpb Scientific, Llc On-chip microfluidic processing of particles
GB201306810D0 (en) 2013-04-15 2013-05-29 Cells4Life Group Llp Methods of cell separation
US10976232B2 (en) 2015-08-24 2021-04-13 Gpb Scientific, Inc. Methods and devices for multi-step cell purification and concentration
CN107418871A (zh) * 2016-05-24 2017-12-01 北京百泰克生物技术有限公司 一种用于富集循环肿瘤细胞的自动化仪器的制作方法
JP6779483B2 (ja) 2016-09-29 2020-11-04 住友ゴム工業株式会社 医療用検査装置及び細胞検査方法
WO2019046052A1 (en) 2017-09-01 2019-03-07 Gpb Scientific, Llc METHODS FOR PREPARING THERAPEUTICALLY ACTIVE CELLS USING MICROFLUIDIC
CN109507427B (zh) * 2017-09-14 2022-05-31 上海白泽医学检验所有限公司 一种基于高亲和力cd45兔单抗的循环肿瘤细胞高效富集方法及其应用
JP7109719B2 (ja) 2018-02-14 2022-08-01 住友ゴム工業株式会社 特定細胞捕捉方法
JP7158671B2 (ja) 2018-02-14 2022-10-24 住友ゴム工業株式会社 特定細胞捕捉方法
US11614440B2 (en) 2019-01-24 2023-03-28 Sumitomo Rubber Industries, Ltd. Specific cell fractionating and capturing methods

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3902964A (en) 1971-12-13 1975-09-02 U S Medical Research And Dev I Method of and apparatus for chemically separating plasma or serum from formed elements of blood
US4097237A (en) * 1977-03-04 1978-06-27 Technicon Instruments Corporation Determination of cells in blood
US4181609A (en) * 1977-12-20 1980-01-01 Levine Robert A Blood constituents testing method
US4752582A (en) * 1982-12-17 1988-06-21 The United States Of America As Represented By The United States Department Of Energy Monoclonal antibodies to human glycophorin A and cell lines for the production thereof
DE3422249A1 (de) * 1984-06-15 1985-12-19 Pfeifer & Langen, 5000 Köln Wasserloesliches eisendextran und verfahren zu seiner herstellung
US4675286A (en) * 1985-01-28 1987-06-23 Aspen Diagnostics, Inc. Fetal cell separation and testing
US4940668A (en) * 1985-11-01 1990-07-10 Becton Dickinson And Company Method for increasing agglutination of groups of cells to produce improved cell layer interface in centrifuged blood sample
US4752563A (en) * 1985-11-19 1988-06-21 Coulter Corporation Monoclonal antibody for recovery of leukocytes in human peripheral blood and method of recovery employing said monoclonal antibody
US4933092A (en) * 1989-04-07 1990-06-12 Abbott Laboratories Methods and devices for the separation of plasma or serum from whole blood
US4994192A (en) * 1990-01-16 1991-02-19 Eastman Kodak Company Amine polymers as coagulator accelerators in blood phase separation
US5118428A (en) * 1990-11-13 1992-06-02 Quidel Method to remove red blood cells from whole blood samples
US5275933A (en) * 1992-09-25 1994-01-04 The Board Of Trustees Of The Leland Stanford Junior University Triple gradient process for recovering nucleated fetal cells from maternal blood
US5766552A (en) * 1993-04-20 1998-06-16 Actimed Laboratories, Inc. Apparatus for red blood cell separation
US5397479A (en) * 1993-04-26 1995-03-14 International Remote Imaging Systems, Inc. Composition and method for enrichment of white blood cells from whole human blood
US5780248A (en) * 1993-07-15 1998-07-14 Ortho Diagnostic Systems, Inc. Foil sealed cassette for agglutination reactions and liner therefor
US5840502A (en) * 1994-08-31 1998-11-24 Activated Cell Therapy, Inc. Methods for enriching specific cell-types by density gradient centrifugation
US5725774A (en) * 1995-04-07 1998-03-10 Lxn Corp. Whole blood separation method and devices using the same
ES2268706T3 (es) * 1995-05-09 2007-03-16 Beckman Coulter, Inc. Dispositivos y procedimientos para separar componentes celulares de la sangre de la porcion liquida de la sangre.
US5877299A (en) * 1995-06-16 1999-03-02 Stemcell Technologies Inc. Methods for preparing enriched human hematopoietic cell preparations
CA2251186A1 (en) * 1996-04-05 1997-10-16 The Johns Hopkins University A method of enriching rare cells
US6365362B1 (en) * 1998-02-12 2002-04-02 Immunivest Corporation Methods and reagents for the rapid and efficient isolation of circulating cancer cells
US6491917B1 (en) * 1998-07-31 2002-12-10 Stemcell Technologies Inc. Antibody composition for debulking blood and bone marrow samples from CML patients
US6153113A (en) * 1999-02-22 2000-11-28 Cobe Laboratories, Inc. Method for using ligands in particle separation
US7011940B1 (en) 1999-04-14 2006-03-14 Medical Discovery Partners Llc Quality control for cytochemical assays
US6750326B2 (en) * 1999-05-28 2004-06-15 Stemcell Technologies Inc. Method for separating cells using immunorosettes
US6448075B1 (en) * 1999-05-28 2002-09-10 Stemcell Technologies Inc. Method for separating cells using immunorosettes
EP1439897B1 (de) * 2001-10-11 2010-09-01 Aviva Biosciences Corporation Verfahren zum trennen von seltenen zellen von fluidproben
DK1553832T3 (da) * 2002-09-27 2007-10-01 Bioe Inc Præparater og fremgangsmåder til celleseparering

Also Published As

Publication number Publication date
WO2007092028A3 (en) 2007-11-22
EP1871870B1 (de) 2010-12-01
ATE490462T1 (de) 2010-12-15
WO2007092028A2 (en) 2007-08-16
EP1871870A2 (de) 2008-01-02
US8263404B2 (en) 2012-09-11
EP1871870A4 (de) 2009-03-25
US20090081632A1 (en) 2009-03-26

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