DE602006018595D1 - Verfahren zum anreichern von subpopulationen seltener zellen aus dem blut - Google Patents
Verfahren zum anreichern von subpopulationen seltener zellen aus dem blutInfo
- Publication number
- DE602006018595D1 DE602006018595D1 DE602006018595T DE602006018595T DE602006018595D1 DE 602006018595 D1 DE602006018595 D1 DE 602006018595D1 DE 602006018595 T DE602006018595 T DE 602006018595T DE 602006018595 T DE602006018595 T DE 602006018595T DE 602006018595 D1 DE602006018595 D1 DE 602006018595D1
- Authority
- DE
- Germany
- Prior art keywords
- blood
- glycophorin
- erythrocytes
- epithelial cells
- subpopulations
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0081—Purging biological preparations of unwanted cells
- C12N5/0087—Purging against subsets of blood cells, e.g. purging alloreactive T cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Zoology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- General Engineering & Computer Science (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Physiology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US66938805P | 2005-04-08 | 2005-04-08 | |
PCT/US2006/012595 WO2007092028A2 (en) | 2005-04-08 | 2006-04-04 | Method for enriching rare cell subpopulations from blood |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602006018595D1 true DE602006018595D1 (de) | 2011-01-13 |
Family
ID=38345583
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602006018595T Active DE602006018595D1 (de) | 2005-04-08 | 2006-04-04 | Verfahren zum anreichern von subpopulationen seltener zellen aus dem blut |
Country Status (5)
Country | Link |
---|---|
US (1) | US8263404B2 (de) |
EP (1) | EP1871870B1 (de) |
AT (1) | ATE490462T1 (de) |
DE (1) | DE602006018595D1 (de) |
WO (1) | WO2007092028A2 (de) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9034658B2 (en) * | 2009-11-23 | 2015-05-19 | The General Hospital Corporation | Microfluidic devices for the capture of biological sample components |
FR2963108B1 (fr) * | 2010-07-21 | 2017-06-23 | Diagast | Procede magnetique d'immunodiagnostic et kit pour la mise en evidence de complexe anticorps/antigene de groupe/phenotype sanguin |
WO2012065185A2 (en) * | 2010-11-11 | 2012-05-18 | Rarecyte, Inc. | Method and system for cell filtration |
WO2012068243A2 (en) * | 2010-11-16 | 2012-05-24 | Ingeneron, Inc. | Methods for obtaining target cells |
CN104081209B (zh) * | 2011-12-06 | 2016-10-19 | 布鲁塞尔大学 | 测定红细胞上存在的抗原或结合至红细胞上存在的抗原的抗体的方法和设备 |
CN103116215A (zh) * | 2013-01-18 | 2013-05-22 | 王亚东 | 基于硝酸纤维素膜的脱落细胞学检查的新型细胞载片构件 |
KR102065112B1 (ko) | 2013-02-28 | 2020-01-10 | 삼성전자주식회사 | 높은 항원 선택성을 갖는 항체의 스크리닝 방법 |
US10324011B2 (en) | 2013-03-15 | 2019-06-18 | The Trustees Of Princeton University | Methods and devices for high throughput purification |
US20150064153A1 (en) | 2013-03-15 | 2015-03-05 | The Trustees Of Princeton University | High efficiency microfluidic purification of stem cells to improve transplants |
WO2014145152A2 (en) | 2013-03-15 | 2014-09-18 | Gpb Scientific, Llc | On-chip microfluidic processing of particles |
GB201306810D0 (en) | 2013-04-15 | 2013-05-29 | Cells4Life Group Llp | Methods of cell separation |
US10976232B2 (en) | 2015-08-24 | 2021-04-13 | Gpb Scientific, Inc. | Methods and devices for multi-step cell purification and concentration |
CN107418871A (zh) * | 2016-05-24 | 2017-12-01 | 北京百泰克生物技术有限公司 | 一种用于富集循环肿瘤细胞的自动化仪器的制作方法 |
JP6779483B2 (ja) | 2016-09-29 | 2020-11-04 | 住友ゴム工業株式会社 | 医療用検査装置及び細胞検査方法 |
WO2019046052A1 (en) | 2017-09-01 | 2019-03-07 | Gpb Scientific, Llc | METHODS FOR PREPARING THERAPEUTICALLY ACTIVE CELLS USING MICROFLUIDIC |
CN109507427B (zh) * | 2017-09-14 | 2022-05-31 | 上海白泽医学检验所有限公司 | 一种基于高亲和力cd45兔单抗的循环肿瘤细胞高效富集方法及其应用 |
JP7109719B2 (ja) | 2018-02-14 | 2022-08-01 | 住友ゴム工業株式会社 | 特定細胞捕捉方法 |
JP7158671B2 (ja) | 2018-02-14 | 2022-10-24 | 住友ゴム工業株式会社 | 特定細胞捕捉方法 |
US11614440B2 (en) | 2019-01-24 | 2023-03-28 | Sumitomo Rubber Industries, Ltd. | Specific cell fractionating and capturing methods |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3902964A (en) | 1971-12-13 | 1975-09-02 | U S Medical Research And Dev I | Method of and apparatus for chemically separating plasma or serum from formed elements of blood |
US4097237A (en) * | 1977-03-04 | 1978-06-27 | Technicon Instruments Corporation | Determination of cells in blood |
US4181609A (en) * | 1977-12-20 | 1980-01-01 | Levine Robert A | Blood constituents testing method |
US4752582A (en) * | 1982-12-17 | 1988-06-21 | The United States Of America As Represented By The United States Department Of Energy | Monoclonal antibodies to human glycophorin A and cell lines for the production thereof |
DE3422249A1 (de) * | 1984-06-15 | 1985-12-19 | Pfeifer & Langen, 5000 Köln | Wasserloesliches eisendextran und verfahren zu seiner herstellung |
US4675286A (en) * | 1985-01-28 | 1987-06-23 | Aspen Diagnostics, Inc. | Fetal cell separation and testing |
US4940668A (en) * | 1985-11-01 | 1990-07-10 | Becton Dickinson And Company | Method for increasing agglutination of groups of cells to produce improved cell layer interface in centrifuged blood sample |
US4752563A (en) * | 1985-11-19 | 1988-06-21 | Coulter Corporation | Monoclonal antibody for recovery of leukocytes in human peripheral blood and method of recovery employing said monoclonal antibody |
US4933092A (en) * | 1989-04-07 | 1990-06-12 | Abbott Laboratories | Methods and devices for the separation of plasma or serum from whole blood |
US4994192A (en) * | 1990-01-16 | 1991-02-19 | Eastman Kodak Company | Amine polymers as coagulator accelerators in blood phase separation |
US5118428A (en) * | 1990-11-13 | 1992-06-02 | Quidel | Method to remove red blood cells from whole blood samples |
US5275933A (en) * | 1992-09-25 | 1994-01-04 | The Board Of Trustees Of The Leland Stanford Junior University | Triple gradient process for recovering nucleated fetal cells from maternal blood |
US5766552A (en) * | 1993-04-20 | 1998-06-16 | Actimed Laboratories, Inc. | Apparatus for red blood cell separation |
US5397479A (en) * | 1993-04-26 | 1995-03-14 | International Remote Imaging Systems, Inc. | Composition and method for enrichment of white blood cells from whole human blood |
US5780248A (en) * | 1993-07-15 | 1998-07-14 | Ortho Diagnostic Systems, Inc. | Foil sealed cassette for agglutination reactions and liner therefor |
US5840502A (en) * | 1994-08-31 | 1998-11-24 | Activated Cell Therapy, Inc. | Methods for enriching specific cell-types by density gradient centrifugation |
US5725774A (en) * | 1995-04-07 | 1998-03-10 | Lxn Corp. | Whole blood separation method and devices using the same |
ES2268706T3 (es) * | 1995-05-09 | 2007-03-16 | Beckman Coulter, Inc. | Dispositivos y procedimientos para separar componentes celulares de la sangre de la porcion liquida de la sangre. |
US5877299A (en) * | 1995-06-16 | 1999-03-02 | Stemcell Technologies Inc. | Methods for preparing enriched human hematopoietic cell preparations |
CA2251186A1 (en) * | 1996-04-05 | 1997-10-16 | The Johns Hopkins University | A method of enriching rare cells |
US6365362B1 (en) * | 1998-02-12 | 2002-04-02 | Immunivest Corporation | Methods and reagents for the rapid and efficient isolation of circulating cancer cells |
US6491917B1 (en) * | 1998-07-31 | 2002-12-10 | Stemcell Technologies Inc. | Antibody composition for debulking blood and bone marrow samples from CML patients |
US6153113A (en) * | 1999-02-22 | 2000-11-28 | Cobe Laboratories, Inc. | Method for using ligands in particle separation |
US7011940B1 (en) | 1999-04-14 | 2006-03-14 | Medical Discovery Partners Llc | Quality control for cytochemical assays |
US6750326B2 (en) * | 1999-05-28 | 2004-06-15 | Stemcell Technologies Inc. | Method for separating cells using immunorosettes |
US6448075B1 (en) * | 1999-05-28 | 2002-09-10 | Stemcell Technologies Inc. | Method for separating cells using immunorosettes |
EP1439897B1 (de) * | 2001-10-11 | 2010-09-01 | Aviva Biosciences Corporation | Verfahren zum trennen von seltenen zellen von fluidproben |
DK1553832T3 (da) * | 2002-09-27 | 2007-10-01 | Bioe Inc | Præparater og fremgangsmåder til celleseparering |
-
2006
- 2006-04-04 US US11/918,012 patent/US8263404B2/en not_active Expired - Fee Related
- 2006-04-04 AT AT06849750T patent/ATE490462T1/de not_active IP Right Cessation
- 2006-04-04 DE DE602006018595T patent/DE602006018595D1/de active Active
- 2006-04-04 EP EP06849750A patent/EP1871870B1/de not_active Not-in-force
- 2006-04-04 WO PCT/US2006/012595 patent/WO2007092028A2/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2007092028A3 (en) | 2007-11-22 |
EP1871870B1 (de) | 2010-12-01 |
ATE490462T1 (de) | 2010-12-15 |
WO2007092028A2 (en) | 2007-08-16 |
EP1871870A2 (de) | 2008-01-02 |
US8263404B2 (en) | 2012-09-11 |
EP1871870A4 (de) | 2009-03-25 |
US20090081632A1 (en) | 2009-03-26 |
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