ATE489452T1 - Zirkulierende tumorzellen (ctc's): frühe beurteilung von time-to-progression, überleben und ansprechen auf therapie bei patienten mit metastasiertem krebs - Google Patents
Zirkulierende tumorzellen (ctc's): frühe beurteilung von time-to-progression, überleben und ansprechen auf therapie bei patienten mit metastasiertem krebsInfo
- Publication number
- ATE489452T1 ATE489452T1 AT04715133T AT04715133T ATE489452T1 AT E489452 T1 ATE489452 T1 AT E489452T1 AT 04715133 T AT04715133 T AT 04715133T AT 04715133 T AT04715133 T AT 04715133T AT E489452 T1 ATE489452 T1 AT E489452T1
- Authority
- AT
- Austria
- Prior art keywords
- ctc
- patients
- survival
- therapy
- response
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45051903P | 2003-02-27 | 2003-02-27 | |
| US52475903P | 2003-11-25 | 2003-11-25 | |
| PCT/US2004/005848 WO2004076643A2 (en) | 2003-02-27 | 2004-02-26 | CIRCULATING TUMOR CELLS (CTC’s): EARLY ASSESSMENT OF TIME TO PROGRESSION SURVIVAL AND RESPONSE TO THERAPY IN METASTATIC CANCER PATIENTS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE489452T1 true ATE489452T1 (de) | 2010-12-15 |
Family
ID=32930557
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04715133T ATE489452T1 (de) | 2003-02-27 | 2004-02-26 | Zirkulierende tumorzellen (ctc's): frühe beurteilung von time-to-progression, überleben und ansprechen auf therapie bei patienten mit metastasiertem krebs |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1597353B1 (de) |
| JP (1) | JP4593557B2 (de) |
| AT (1) | ATE489452T1 (de) |
| CA (1) | CA2516795C (de) |
| DE (1) | DE602004030220D1 (de) |
| WO (1) | WO2004076643A2 (de) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8980568B2 (en) | 2001-10-11 | 2015-03-17 | Aviva Biosciences Corporation | Methods and compositions for detecting non-hematopoietic cells from a blood sample |
| US8986944B2 (en) | 2001-10-11 | 2015-03-24 | Aviva Biosciences Corporation | Methods and compositions for separating rare cells from fluid samples |
| AU2003277153A1 (en) | 2002-09-27 | 2004-04-19 | The General Hospital Corporation | Microfluidic device for cell separation and uses thereof |
| PL1861509T3 (pl) * | 2005-03-14 | 2016-01-29 | Janssen Diagnostics Llc | Sposób predykcji przeżywalności bez progresji i przeżywalności całkowitej przy wizytach kontrolnych w trakcie terapii u pacjentów z rozsianym rakiem piersi wykorzystujący krążące komórki nowotworowe |
| US20070196820A1 (en) | 2005-04-05 | 2007-08-23 | Ravi Kapur | Devices and methods for enrichment and alteration of cells and other particles |
| US8921102B2 (en) | 2005-07-29 | 2014-12-30 | Gpb Scientific, Llc | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| US7507534B2 (en) | 2005-09-01 | 2009-03-24 | National Health Research Institutes | Rapid efficacy assessment method for lung cancer therapy |
| US9134237B2 (en) | 2005-09-20 | 2015-09-15 | Janssen Diagnotics, LLC | High sensitivity multiparameter method for rare event analysis in a biological sample |
| US9127302B2 (en) | 2005-09-20 | 2015-09-08 | Janssen Diagnostics, Llc | System for the detection and enumeration of suspect target cells in a mixed cell population |
| JP4986449B2 (ja) * | 2005-12-27 | 2012-07-25 | 株式会社エスアールエル | 浮遊細胞の検査方法 |
| JP2009534666A (ja) * | 2006-04-18 | 2009-09-24 | ウェルスタット バイオロジックス コーポレイション | 循環内皮細胞の検出 |
| JP5078100B2 (ja) * | 2006-04-18 | 2012-11-21 | ウェルスタット バイオロジクス コーポレイション | 循環癌細胞におけるステロイド受容体の検出および処置 |
| US8114615B2 (en) | 2006-05-17 | 2012-02-14 | Cernostics, Inc. | Method for automated tissue analysis |
| WO2007139895A2 (en) * | 2006-05-24 | 2007-12-06 | Cellumen, Inc. | Method for modeling a disease |
| US20080050739A1 (en) | 2006-06-14 | 2008-02-28 | Roland Stoughton | Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats |
| US8137912B2 (en) | 2006-06-14 | 2012-03-20 | The General Hospital Corporation | Methods for the diagnosis of fetal abnormalities |
| EP2029779A4 (de) | 2006-06-14 | 2010-01-20 | Living Microsystems Inc | Verwendung hoch paralleler snp-genotypisierung zur fötalen diagnose |
| US8372584B2 (en) | 2006-06-14 | 2013-02-12 | The General Hospital Corporation | Rare cell analysis using sample splitting and DNA tags |
| CN101583722A (zh) | 2006-07-14 | 2009-11-18 | 阿维瓦生物科学股份有限公司 | 从生物学样品检测稀有细胞的方法和组合物 |
| US20080108091A1 (en) * | 2006-08-07 | 2008-05-08 | Hennessy Bryan T | Proteomic Patterns of Cancer Prognostic and Predictive Signatures |
| WO2008130910A1 (en) * | 2007-04-19 | 2008-10-30 | Wellstat Biologics Corporation | Detection her-2/neu protein from non-isolated circulating cancer cells and treatment |
| EP2229441B1 (de) | 2007-12-12 | 2014-10-01 | The Board of Trustees of The Leland Stanford Junior University | Verfahren und vorrichtung zur magnetischen trennung von zellen |
| US8008032B2 (en) | 2008-02-25 | 2011-08-30 | Cellective Dx Corporation | Tagged ligands for enrichment of rare analytes from a mixed sample |
| US20090258365A1 (en) | 2008-03-25 | 2009-10-15 | Terstappen Leon W M M | METHOD FOR DETECTING IGF1R/Chr 15 in CIRCULATING TUMOR CELLS USING FISH |
| ES2620012T3 (es) | 2008-09-20 | 2017-06-27 | The Board Of Trustees Of The Leland Stanford Junior University | Diagnóstico no invasivo de la aneuploidia fetal por secuenciación |
| CN102414562B (zh) * | 2009-03-24 | 2019-05-07 | 生物概念股份有限公司 | 细胞捕获和分析的装置和方法 |
| US20120100538A1 (en) | 2009-03-24 | 2012-04-26 | Biocept, Inc. | Devices and methods of cell capture and analysis |
| TWI539158B (zh) * | 2010-06-08 | 2016-06-21 | 維里德克斯有限責任公司 | 使用血液中之循環黑色素瘤細胞預測黑色素瘤病患之臨床結果的方法。 |
| US8790878B2 (en) | 2010-07-07 | 2014-07-29 | The Regents Of The University Of Michigan | Diagnosis and treatment of breast cancer |
| EP3553527A1 (de) | 2011-03-17 | 2019-10-16 | Cernostics, Inc. | Systeme und zusammensetzungen zur diagnose von barrett-ösophagen und verfahren zur verwendung davon |
| US20120252038A1 (en) * | 2011-04-01 | 2012-10-04 | Chianese David A | Steroid receptor assays |
| JP2012022002A (ja) * | 2011-09-12 | 2012-02-02 | Veridex Llc | 循環腫瘍細胞を用いる転移性乳癌患者の療法中の各追跡期間ポイントでの無増悪および全生存を予測する方法 |
| JP6080035B2 (ja) * | 2012-09-07 | 2017-02-15 | 日立化成株式会社 | 膜、基体及び細胞の採取方法 |
| US20150064153A1 (en) | 2013-03-15 | 2015-03-05 | The Trustees Of Princeton University | High efficiency microfluidic purification of stem cells to improve transplants |
| CN105264127B (zh) | 2013-03-15 | 2019-04-09 | Gpb科学有限责任公司 | 颗粒的片上微流体处理 |
| US10324011B2 (en) | 2013-03-15 | 2019-06-18 | The Trustees Of Princeton University | Methods and devices for high throughput purification |
| KR101630110B1 (ko) | 2013-07-24 | 2016-06-13 | 가부시끼가이샤 옵토니쿠스 세이미쯔 | 말초 순환 종양 세포 또는 희소 세포 분리용 디바이스 및 말초 순환 종양 세포 또는 희소 세포 분리 방법 |
| CN103630440A (zh) * | 2013-11-28 | 2014-03-12 | 武汉大学 | 一种循环肿瘤细胞的富集方法 |
| US20150160246A1 (en) | 2013-12-11 | 2015-06-11 | Analiza, Inc. | Devices and methods for determining and/or isolating cells such as circulating cancer or fetal cells |
| US9709556B2 (en) | 2013-12-11 | 2017-07-18 | Analiza, Inc. | Devices and methods for determining and/or isolating circulating cancer cells |
| WO2016172160A1 (en) * | 2015-04-21 | 2016-10-27 | Genentech, Inc. | Compositions and methods for prostate cancer analysis |
| WO2016172427A1 (en) * | 2015-04-22 | 2016-10-27 | Immunomedics, Inc. | Isolation, detection, diagnosis and/or characterization of circulating trop-2-positive cancer cells |
| KR101701618B1 (ko) | 2015-06-23 | 2017-02-13 | 국립암센터 | 전도성 고분자를 이용한 세포 유리 dna 검출용 구조체 및 이의 용도 |
| US10976232B2 (en) | 2015-08-24 | 2021-04-13 | Gpb Scientific, Inc. | Methods and devices for multi-step cell purification and concentration |
| WO2017040686A1 (en) * | 2015-09-01 | 2017-03-09 | University Of Miami | Identification of circulating cancer associated fibroblasts |
| EP4152001B1 (de) | 2015-11-25 | 2025-10-22 | Cernostics, Inc. | Verfahren zur einstufung von barrett-ösophagus |
| KR101994370B1 (ko) * | 2016-08-24 | 2019-06-28 | 주식회사 제놉시 | 항체 및 자성 나노 입자가 결합된 전도성 고분자를 포함하는 혈중 암세포 검출 및 회수용 자성 나노 구조체 |
| CN106222161A (zh) * | 2016-08-29 | 2016-12-14 | 温州医科大学附属第二医院 | 纳米磁颗粒捕获癌细胞的方法及其应用 |
| BR112019018767A2 (pt) | 2017-04-03 | 2020-05-05 | Hoffmann La Roche | anticorpos, molécula de ligação ao antígeno biespecífica, um ou mais polinucleotídeos isolados, um ou mais vetores, célula hospedeira, método para produzir um anticorpo, composição farmacêutica, usos, método para tratar uma doença em um indivíduo e invenção |
| US20200408740A1 (en) * | 2017-09-04 | 2020-12-31 | Cannabics Pharmaceuticals Inc. | Method for sensitivity testing of cannabinoids on patientderived tumor biopsies and ctcs |
| WO2021245677A1 (en) * | 2020-06-05 | 2021-12-09 | Digestix Bioscience Inc. | Compositions and methods for treating dysplastic and early-stage neoplastic conditions |
| CN112116977B (zh) * | 2020-08-12 | 2024-05-10 | 浙江大学 | 一种非小细胞肺癌患者疗效及预后预测系统 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5993388A (en) * | 1997-07-01 | 1999-11-30 | Kattan; Michael W. | Nomograms to aid in the treatment of prostatic cancer |
| JP2002503814A (ja) | 1998-02-12 | 2002-02-05 | イムニベスト・コーポレイション | 循環ガン細胞の迅速かつ効率的な単離のための方法および試薬 |
| US20010018192A1 (en) | 1998-02-12 | 2001-08-30 | Terstappen Leon W.M.M. | Labeled cells for use as an internal functional control in rare cell detection assays |
| US20020172987A1 (en) * | 1998-02-12 | 2002-11-21 | Terstappen Leon W.M.M. | Methods and reagents for the rapid and efficient isolation of circulating cancer cells |
| US6551843B1 (en) | 1999-01-29 | 2003-04-22 | Immunivest Corporation | Methods for enhancing binding interactions between members of specific binding pairs |
| AU2876900A (en) * | 1999-02-10 | 2000-08-29 | Cell Works Inc. | Class characterization of circulating cancer cells isolated from body fluids andmethods of use |
| US6623982B1 (en) | 1999-07-12 | 2003-09-23 | Immunivest Corporation | Increased separation efficiency via controlled aggregation of magnetic nanoparticles |
| CA2426571A1 (en) * | 2000-11-01 | 2002-05-10 | Eleftherios P. Diamandis | Detection of ovarian cancer |
| EP1360496A4 (de) | 2001-02-16 | 2005-03-09 | Immunivest Corp | Verfahren und reagenzien zur schnellen und effizienten isolierung zirkulierender krebszellen |
| US7229774B2 (en) * | 2001-08-02 | 2007-06-12 | Regents Of The University Of Michigan | Expression profile of prostate cancer |
| WO2003019141A2 (en) | 2001-08-23 | 2003-03-06 | Immunivest Corporation | Analysis of circulating tumor cells, fragments, and debris |
-
2004
- 2004-02-26 EP EP04715133A patent/EP1597353B1/de not_active Expired - Lifetime
- 2004-02-26 AT AT04715133T patent/ATE489452T1/de not_active IP Right Cessation
- 2004-02-26 DE DE602004030220T patent/DE602004030220D1/de not_active Expired - Lifetime
- 2004-02-26 JP JP2006503899A patent/JP4593557B2/ja not_active Expired - Lifetime
- 2004-02-26 CA CA2516795A patent/CA2516795C/en not_active Expired - Lifetime
- 2004-02-26 WO PCT/US2004/005848 patent/WO2004076643A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP1597353B1 (de) | 2010-11-24 |
| CA2516795A1 (en) | 2004-09-10 |
| EP1597353A4 (de) | 2007-10-31 |
| WO2004076643A2 (en) | 2004-09-10 |
| EP1597353A2 (de) | 2005-11-23 |
| JP2007525642A (ja) | 2007-09-06 |
| JP4593557B2 (ja) | 2010-12-08 |
| DE602004030220D1 (de) | 2011-01-05 |
| CA2516795C (en) | 2013-01-15 |
| WO2004076643A3 (en) | 2007-03-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |