ATE489391T1 - Neue 4-amino-3-(-azolylphenoxymethyl)thienoä3,2- cüpyridin-7-carbonsäurederivate - Google Patents

Neue 4-amino-3-(-azolylphenoxymethyl)thienoä3,2- cüpyridin-7-carbonsäurederivate

Info

Publication number
ATE489391T1
ATE489391T1 AT07730300T AT07730300T ATE489391T1 AT E489391 T1 ATE489391 T1 AT E489391T1 AT 07730300 T AT07730300 T AT 07730300T AT 07730300 T AT07730300 T AT 07730300T AT E489391 T1 ATE489391 T1 AT E489391T1
Authority
AT
Austria
Prior art keywords
thienoä3
cupyridine
azolylphenoxymethyl
amino
new
Prior art date
Application number
AT07730300T
Other languages
English (en)
Inventor
Yi Chen
Kin-Chun Thomas Luk
Pamela Loreen Rossman
Sung-Sau So
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE489391T1 publication Critical patent/ATE489391T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
AT07730300T 2006-06-29 2007-06-22 Neue 4-amino-3-(-azolylphenoxymethyl)thienoä3,2- cüpyridin-7-carbonsäurederivate ATE489391T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81761606P 2006-06-29 2006-06-29
PCT/EP2007/056241 WO2008000697A1 (en) 2006-06-29 2007-06-22 Novel 4-amino-3-(-azolyl-phenoxymethyl)-thieno[3,2]pyridine-7-carboxylic acid derivatives

Publications (1)

Publication Number Publication Date
ATE489391T1 true ATE489391T1 (de) 2010-12-15

Family

ID=38514272

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07730300T ATE489391T1 (de) 2006-06-29 2007-06-22 Neue 4-amino-3-(-azolylphenoxymethyl)thienoä3,2- cüpyridin-7-carbonsäurederivate

Country Status (16)

Country Link
US (1) US7932390B2 (de)
EP (1) EP2038288B1 (de)
JP (1) JP4933617B2 (de)
KR (1) KR101143286B1 (de)
CN (1) CN101479278B (de)
AT (1) ATE489391T1 (de)
BR (1) BRPI0713041A8 (de)
CA (1) CA2655398C (de)
DE (1) DE602007010779D1 (de)
DK (1) DK2038288T3 (de)
ES (1) ES2354637T3 (de)
IL (1) IL195897A (de)
MX (1) MX2008016068A (de)
PL (1) PL2038288T3 (de)
PT (1) PT2038288E (de)
WO (1) WO2008000697A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9540322B2 (en) 2008-08-18 2017-01-10 Yale University MIF modulators
KR20180032686A (ko) * 2010-03-24 2018-03-30 아미텍 테러퓨틱 솔루션즈 인크 인산화효소 억제에 유용한 헤테로환 화합물

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2732970B1 (fr) 1995-04-14 1997-05-16 Hoechst Schering Agrevo Sa Nouveaux derives de l'acide beta-methoxy acrylique, leur procede de preparation et leur application comme pesticides
UA60365C2 (uk) 1998-06-04 2003-10-15 Пфайзер Продактс Інк. Похідні ізотіазолу, спосіб їх одержання, фармацевтична композиція та спосіб лікування гіперпроліферативного захворювання у ссавця
US6232320B1 (en) 1998-06-04 2001-05-15 Abbott Laboratories Cell adhesion-inhibiting antiinflammatory compounds
HN2000000051A (es) 1999-05-19 2001-02-02 Pfizer Prod Inc Derivados heterociclicos utiles como agentes anticancerosos
ATE340786T1 (de) 2000-11-28 2006-10-15 Pfizer Prod Inc Salze eines 4-isothiazolcarboxamids und ihre verwendung als anti-hyperproliferationsmittel
CA2480638C (en) * 2002-03-29 2013-02-12 Chiron Corporation Substituted benzazoles and use thereof as raf kinase inhibitors
JP2006512313A (ja) 2002-10-31 2006-04-13 アムジェン インコーポレイテッド 抗炎症剤
US7592352B2 (en) 2003-05-06 2009-09-22 Smithkline Beecham Corporation Substituted thieno and furo-pyridines
US7202363B2 (en) 2003-07-24 2007-04-10 Abbott Laboratories Thienopyridine and furopyridine kinase inhibitors
US20050020619A1 (en) 2003-07-24 2005-01-27 Patrick Betschmann Thienopyridine kinase inhibitors
US20050026944A1 (en) 2003-07-24 2005-02-03 Patrick Betschmann Thienopyridine and furopyridine kinase inhibitors
KR20070029643A (ko) 2003-12-05 2007-03-14 베링거 인겔하임 파마슈티칼즈, 인코포레이티드 ＩＫＫ 억제제로서의 치환된3-아미노-티에노[2,3-ｂ]피리딘-2-카복실산 아미드 화합물
US20050256154A1 (en) 2004-05-04 2005-11-17 Kin-Chun Luk 4-Amino-thieno[3,2-c]pyridine-7-carboxylic acid amides

Also Published As

Publication number Publication date
BRPI0713041A8 (pt) 2019-01-15
JP2009541424A (ja) 2009-11-26
WO2008000697A1 (en) 2008-01-03
ES2354637T3 (es) 2011-03-16
US7932390B2 (en) 2011-04-26
KR20090021195A (ko) 2009-02-27
US20080009515A1 (en) 2008-01-10
IL195897A (en) 2016-04-21
CN101479278B (zh) 2011-12-07
EP2038288B1 (de) 2010-11-24
PT2038288E (pt) 2011-01-12
CN101479278A (zh) 2009-07-08
MX2008016068A (es) 2009-01-15
DE602007010779D1 (en) 2011-01-05
PL2038288T3 (pl) 2011-05-31
CA2655398C (en) 2014-07-29
DK2038288T3 (da) 2011-01-03
CA2655398A1 (en) 2008-01-03
JP4933617B2 (ja) 2012-05-16
KR101143286B1 (ko) 2012-05-24
BRPI0713041A2 (pt) 2012-04-17
IL195897A0 (en) 2009-09-01
AU2007263770A1 (en) 2008-01-03
EP2038288A1 (de) 2009-03-25

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