ATE487134T1 - Verfahren zur bestimmung der menge konjugierten taxans in polyglutaminsäure-taxan-konjugaten - Google Patents

Verfahren zur bestimmung der menge konjugierten taxans in polyglutaminsäure-taxan-konjugaten

Info

Publication number
ATE487134T1
ATE487134T1 AT07004574T AT07004574T ATE487134T1 AT E487134 T1 ATE487134 T1 AT E487134T1 AT 07004574 T AT07004574 T AT 07004574T AT 07004574 T AT07004574 T AT 07004574T AT E487134 T1 ATE487134 T1 AT E487134T1
Authority
AT
Austria
Prior art keywords
determining
amount
conjugated
taxane
taxans
Prior art date
Application number
AT07004574T
Other languages
English (en)
Inventor
Stefano Fazioni
Keith Hovda
Valeria Livi
Marc Mckennon
Luigi Siviero
Holly Spoonemore
Original Assignee
Cell Therapeutics Europe Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cell Therapeutics Europe Srl filed Critical Cell Therapeutics Europe Srl
Application granted granted Critical
Publication of ATE487134T1 publication Critical patent/ATE487134T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT07004574T 2007-03-06 2007-03-06 Verfahren zur bestimmung der menge konjugierten taxans in polyglutaminsäure-taxan-konjugaten ATE487134T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP07004574A EP1967854B8 (de) 2007-03-06 2007-03-06 Verfahren zur Bestimmung der Menge konjugierten Taxans in Polyglutaminsäure-Taxan-Konjugaten

Publications (1)

Publication Number Publication Date
ATE487134T1 true ATE487134T1 (de) 2010-11-15

Family

ID=38121284

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07004574T ATE487134T1 (de) 2007-03-06 2007-03-06 Verfahren zur bestimmung der menge konjugierten taxans in polyglutaminsäure-taxan-konjugaten

Country Status (15)

Country Link
US (1) US8318503B2 (de)
EP (1) EP1967854B8 (de)
JP (1) JP5133357B2 (de)
KR (1) KR101514833B1 (de)
CN (1) CN101641598B (de)
AT (1) ATE487134T1 (de)
AU (1) AU2008224139B2 (de)
BR (1) BRPI0808494A2 (de)
CA (1) CA2680073C (de)
DE (1) DE602007010232D1 (de)
ES (1) ES2353653T3 (de)
HK (1) HK1119247A1 (de)
MX (1) MX2009009477A (de)
RU (1) RU2447443C2 (de)
WO (1) WO2008107174A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2604718C2 (ru) 2010-05-27 2016-12-10 Шэньчжэнь Салубрис Фармасьютикалз Ко.,Лтд. Химический синтез и противоопухолевый и противометастатический эффекты конъюгата двойного действия
JP5918274B2 (ja) 2011-02-02 2016-05-18 オンタリオ インスティテュート フォー キャンサー リサーチ 薬物送達のためのセルロース系ナノ粒子
KR101787447B1 (ko) 2015-07-28 2017-10-19 주식회사 삼양바이오팜 보관 안정성이 향상된 약학 조성물 및 그의 제조 방법
KR101787451B1 (ko) 2015-07-28 2017-10-19 주식회사 삼양바이오팜 보관 안정성이 향상된 약학 조성물 및 그의 제조 방법
CN115521229A (zh) * 2022-10-09 2022-12-27 无锡紫杉药业股份有限公司 一种多西他赛四元环开环产物的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2250295C (en) 1996-03-12 2008-12-30 Pg-Txl Company L.P. Water soluble paclitaxel prodrugs
CN1111166C (zh) * 1999-09-10 2003-06-11 云南汉德生物技术有限公司 水溶性三尖杉磷碱聚氨基酸酯或其盐,含它们的药物组合物及其医药用途
US6281368B1 (en) * 2000-03-16 2001-08-28 Napro Biotherapeutics, Inc. Simple and efficient hydrazinolysis of C-10 and C-13 ester functionalities of taxanes to obtain 10-DAB III
US6495705B2 (en) * 2000-03-16 2002-12-17 Napro Biotherapeutics, Inc. Efficient process for the production of 10-DAB III by selective hydrazinolysis of various taxanes

Also Published As

Publication number Publication date
EP1967854A1 (de) 2008-09-10
CA2680073C (en) 2016-04-19
ES2353653T3 (es) 2011-03-03
EP1967854B1 (de) 2010-11-03
RU2009133346A (ru) 2011-03-10
DE602007010232D1 (de) 2010-12-16
CA2680073A1 (en) 2008-09-12
RU2447443C2 (ru) 2012-04-10
CN101641598B (zh) 2014-09-24
KR101514833B1 (ko) 2015-04-24
MX2009009477A (es) 2009-12-01
EP1967854B8 (de) 2010-12-29
JP5133357B2 (ja) 2013-01-30
AU2008224139A1 (en) 2008-09-12
US20100151582A1 (en) 2010-06-17
AU2008224139B2 (en) 2012-08-23
BRPI0808494A2 (pt) 2014-07-22
US8318503B2 (en) 2012-11-27
KR20090125763A (ko) 2009-12-07
CN101641598A (zh) 2010-02-03
HK1119247A1 (en) 2009-02-27
WO2008107174A1 (en) 2008-09-12
JP2010520468A (ja) 2010-06-10

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