ATE486587T1 - Formulierungen zur oralen verabreichung von wirkstoffen - Google Patents

Formulierungen zur oralen verabreichung von wirkstoffen

Info

Publication number
ATE486587T1
ATE486587T1 AT03729449T AT03729449T ATE486587T1 AT E486587 T1 ATE486587 T1 AT E486587T1 AT 03729449 T AT03729449 T AT 03729449T AT 03729449 T AT03729449 T AT 03729449T AT E486587 T1 ATE486587 T1 AT E486587T1
Authority
AT
Austria
Prior art keywords
oral administration
formulations
active ingredients
pharmaceutical compositions
relates
Prior art date
Application number
AT03729449T
Other languages
German (de)
English (en)
Inventor
Domenico Fanara
Monique Berwaer
Anthony Guichaux
Michel Deleers
Original Assignee
Ucb Farchim Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Farchim Sa filed Critical Ucb Farchim Sa
Application granted granted Critical
Publication of ATE486587T1 publication Critical patent/ATE486587T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A61K9/0058—Chewing gums
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/282—Organic compounds, e.g. fats
    • A61K9/2826—Sugars or sugar alcohols, e.g. sucrose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT03729449T 2002-01-15 2003-01-14 Formulierungen zur oralen verabreichung von wirkstoffen ATE486587T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02000871 2002-01-15
PCT/EP2003/000260 WO2003059328A1 (en) 2002-01-15 2003-01-14 Formulations

Publications (1)

Publication Number Publication Date
ATE486587T1 true ATE486587T1 (de) 2010-11-15

Family

ID=8185261

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03729449T ATE486587T1 (de) 2002-01-15 2003-01-14 Formulierungen zur oralen verabreichung von wirkstoffen

Country Status (19)

Country Link
US (3) US20050038039A1 (enExample)
EP (1) EP1467715B1 (enExample)
JP (4) JP4724367B2 (enExample)
KR (1) KR101005648B1 (enExample)
CN (2) CN100455287C (enExample)
AT (1) ATE486587T1 (enExample)
AU (3) AU2003201161B2 (enExample)
BR (1) BR0306870A (enExample)
CA (1) CA2472396A1 (enExample)
CO (1) CO5590918A2 (enExample)
DE (1) DE60334773D1 (enExample)
ES (1) ES2354688T3 (enExample)
MX (1) MXPA04006775A (enExample)
NO (1) NO333936B1 (enExample)
NZ (1) NZ534039A (enExample)
PL (1) PL212123B1 (enExample)
RU (1) RU2004123612A (enExample)
WO (1) WO2003059328A1 (enExample)
ZA (1) ZA200404796B (enExample)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE388693T1 (de) * 2002-04-04 2008-03-15 Pfizer Prod Inc Wohlschmeckende kautablette
EP2260871B1 (fr) * 2004-04-01 2013-05-15 Pierre Fabre Medicament Complexes d'inclusions comprenant du piroxicam, une cyclodextrine et l'arginine
US7318935B2 (en) * 2004-05-21 2008-01-15 Accu-Break Technologies, Inc. Pharmaceutical tablets with active and inactive segments
US7838031B2 (en) 2004-05-21 2010-11-23 Lawrence Solomon Method of administering a partial dose using a segmented pharmaceutical tablet
US7622137B2 (en) * 2004-05-21 2009-11-24 Accu-Break Technologies, Inc. Dosage forms contained within a capsule or sachet
US8158148B2 (en) * 2004-05-21 2012-04-17 Accu-Break Technologies, Inc. Pharmaceutical tablets comprising two or more unitary segments
US7713547B2 (en) 2004-05-21 2010-05-11 Accu-Break Pharmaceuticals, Inc. Method of administering a partial dose of a segmented pharmaceutical tablet
US7329418B2 (en) * 2004-05-21 2008-02-12 Accu Break Technologies, Inc. Pharmaceutical tablets having height greater than width
US7780985B2 (en) * 2005-07-12 2010-08-24 Accu-Break Technologies, Inc. Tablets having a printed separation mark to guide breaking
BRPI0513455A (pt) * 2004-07-22 2008-05-06 Pfizer Prod Inc formulação para mascaramento de sabor compreendendo o fármaco em uma forma de dissolução retardada e/ou ciclodextrina em uma forma de dissolução melhorada
US20060083786A1 (en) * 2004-07-29 2006-04-20 Glenmark Pharmaceuticals Limited Taste masking pharmaceutical composition containing levocetirizine
KR100714616B1 (ko) * 2005-06-23 2007-05-07 삼성전기주식회사 지수 함수 발생기 및 이를 이용한 가변 이득 증폭기
US20070086974A1 (en) * 2005-10-06 2007-04-19 Gawande Rahul S Cetirizine compositions
WO2007058660A1 (en) * 2005-11-18 2007-05-24 Accu-Break Technologies, Inc. Segmented pharmaceutical dosage forms
US20070237815A1 (en) * 2006-04-06 2007-10-11 Lawrence Solomon Dosage forms and methods comprising amlodipine and chlorthalidone
WO2007144902A1 (en) * 2006-06-12 2007-12-21 Jubliant Organosys Limited Chewable bilayer tablet formulation
US20110086092A1 (en) * 2006-08-08 2011-04-14 Accu-Break Technologies, Inc. Pharmacuetical tablets containing a plurality of active ingredients
EP2083801A1 (en) * 2006-11-30 2009-08-05 Accu-Break Technologies, Inc. Divisible osmotic dosage forms and methods of use
US20090004231A1 (en) 2007-06-30 2009-01-01 Popp Shane M Pharmaceutical dosage forms fabricated with nanomaterials for quality monitoring
EP2550967A1 (en) * 2007-07-11 2013-01-30 Fertin Pharma A/S Compressed chewing gum tablet comprising taste-masking agent
US20100260818A1 (en) * 2007-07-11 2010-10-14 Fertin Pharma A/S Stable medicated chewing gum comprising cyclodextrin inclusion complex
EP2296486B1 (en) * 2008-05-26 2015-04-29 Fertin Pharma A/S Film-coated compressed chewing gum
CA2734691C (en) 2008-09-05 2017-05-16 Mcneil-Ppc, Inc. Method for making cetirizine tablets
WO2010107404A1 (en) 2009-03-16 2010-09-23 Mahmut Bilgic Stable pharmaceutical combinations
WO2011110939A2 (en) 2010-03-11 2011-09-15 Rubicon Research Private Limited Pharmaceutical compositions of substituted benzhydrylpiperazines
WO2011146032A2 (en) * 2010-05-18 2011-11-24 Mahmut Bilgic Effervescent formulations
US20170105988A1 (en) * 2014-03-27 2017-04-20 Ucb Biopharma Sprl Pharmaceutical Compositions Comprising Levocetirizine
JP2016094364A (ja) * 2014-11-14 2016-05-26 ニプロ株式会社 安定化および苦味抑制された口腔内崩壊製剤
JP7049610B2 (ja) * 2018-05-21 2022-04-07 高田製薬株式会社 レボセチリジン固形製剤
KR20220137065A (ko) 2020-02-03 2022-10-11 존슨 앤드 존슨 컨수머 인코포레이티드 세티리진을 포함하는 단일층 츄어블 정제
US20230366038A1 (en) * 2022-05-16 2023-11-16 Bioo Scientific Corporation Compositions and methods relating to loop mediated isothermal amplification (lamp)

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4238510A (en) * 1979-02-21 1980-12-09 Life Savers, Inc. Sugarless coating for chewing gum and confections and method
US4260596A (en) * 1979-08-13 1981-04-07 Bristol-Myers Company Edible unit dosage form consisting of outer mannitol shell and inner liquid or gel center and method for manufacturing the same
FR2647343B1 (fr) 1989-05-24 1994-05-06 Rhone Poulenc Sante Nouvelle forme pharmaceutique poreuse et sa preparation
US5460825A (en) * 1990-05-23 1995-10-24 Mcneil-Ppc, Inc. Taste mask coatings for preparing chewable pharmaceutical tablets
NZ243667A (en) * 1991-08-02 1995-02-24 Kurihara Yoshie Chewing gum containing coated curculin derivative or fruit containing curculin
TW401300B (en) * 1992-12-25 2000-08-11 Senju Pharma Co Antiallergic composition for ophthalmic or nasal use
US5380530A (en) * 1992-12-29 1995-01-10 Whitehill Oral Technologies Oral care composition coated gum
CA2128820A1 (en) 1993-07-27 1995-01-28 Walter G. Gowan, Jr. Rapidly disintegrating pharmaceutical dosage form and process for preparation thereof
HU213407B (en) 1993-12-09 1997-06-30 Egyt Gyogyszervegyeszeti Gyar Process for producing tablet with diffusive-osmotic release
IT1274034B (it) * 1994-07-26 1997-07-14 Applied Pharma Res Composizioni farmaceutiche a base di gomma da masticare e procedimento per la loro preparazione
US5866179A (en) * 1996-05-03 1999-02-02 Avant-Garde Technologies & Products S.A. Medicated chewing gum and a process for preparation thereof
EP0811374A1 (en) 1996-05-29 1997-12-10 Pfizer Inc. Combination dosage form comprising cetirizine and pseudoephedrine
US6172095B1 (en) * 1996-11-25 2001-01-09 The Procter & Gamble Company Guanidinylamino heterocycle compounds useful as alpha-2 adrenoceptor agonists
WO2000035298A1 (en) 1996-11-27 2000-06-22 Wm. Wrigley Jr. Company Chewing gum containing medicament active agents
BE1011251A3 (fr) * 1997-07-03 1999-06-01 Ucb Sa Compositions pharmaceutiques administrables par voie orale, comprenant une substance active et une cyclodextrine.
ATE288742T1 (de) * 1997-07-10 2005-02-15 Gergely Dr & Co Lösliche, gummihaltige, dragierte kautablette
DE19814256A1 (de) * 1998-03-31 1999-10-07 Asta Medica Ag Feste, schnellzerfallende Cetirizin-Formulierungen
US6319513B1 (en) * 1998-08-24 2001-11-20 The Procter & Gamble Company Oral liquid mucoadhesive compounds
US6627234B1 (en) * 1998-12-15 2003-09-30 Wm. Wrigley Jr. Company Method of producing active agent coated chewing gum products
EP1311240A1 (en) * 2000-08-14 2003-05-21 Fertin Pharma A/S Method for preparation of chewing gum with customer acceptable taste
WO2002049607A2 (en) * 2000-12-20 2002-06-27 Firmenich Sa Flavoured oral drug delivery system
US20030035839A1 (en) * 2001-05-15 2003-02-20 Peirce Management, Llc Pharmaceutical composition for both intraoral and oral administration
US7014867B2 (en) * 2001-06-28 2006-03-21 Ucb Farchim Sa Tablet comprising cetirizine and pseudoephedrine
ATE388693T1 (de) * 2002-04-04 2008-03-15 Pfizer Prod Inc Wohlschmeckende kautablette

Also Published As

Publication number Publication date
CN101632642B (zh) 2011-06-08
EP1467715B1 (en) 2010-11-03
JP5467685B2 (ja) 2014-04-09
NZ534039A (en) 2006-08-31
ZA200404796B (en) 2005-06-29
JP2005518405A (ja) 2005-06-23
CN101632642A (zh) 2010-01-27
CO5590918A2 (es) 2005-12-30
AU2003201161B2 (en) 2008-02-28
JP4724367B2 (ja) 2011-07-13
KR101005648B1 (ko) 2011-01-05
JP5623447B2 (ja) 2014-11-12
KR20040075075A (ko) 2004-08-26
WO2003059328A1 (en) 2003-07-24
US20120010218A1 (en) 2012-01-12
NO333936B1 (no) 2013-10-28
CA2472396A1 (en) 2003-07-24
MXPA04006775A (es) 2004-11-10
PL212123B1 (pl) 2012-08-31
JP2012121917A (ja) 2012-06-28
EP1467715A1 (en) 2004-10-20
CN1615124A (zh) 2005-05-11
PL370292A1 (en) 2005-05-16
JP2014024866A (ja) 2014-02-06
AU2003201161A1 (en) 2003-07-30
CN100455287C (zh) 2009-01-28
AU2008202280B2 (en) 2009-05-21
NO20043367L (no) 2004-08-13
DE60334773D1 (de) 2010-12-16
RU2004123612A (ru) 2005-04-20
BR0306870A (pt) 2004-11-03
US20050038039A1 (en) 2005-02-17
US8946229B2 (en) 2015-02-03
US20090047344A1 (en) 2009-02-19
AU2009203044B2 (en) 2010-06-17
ES2354688T3 (es) 2011-03-17
HK1076605A1 (zh) 2006-01-20
JP2010120963A (ja) 2010-06-03
AU2008202280A1 (en) 2008-06-12
AU2009203044A1 (en) 2009-08-13

Similar Documents

Publication Publication Date Title
ATE486587T1 (de) Formulierungen zur oralen verabreichung von wirkstoffen
NO20051102L (no) Sulfonylamino-eddiksyre-derivater
BR0214343A (pt) Inibidores de 11 - beta - hidroxi esteróide desidrogenase tipo 1
BG66093B1 (bg) Състави с контролирано освобождаване, съдържащи нимесулид
NO20070224L (no) 2-karbamid-4-fenyltiazolderivater, fremstilling og terapeutisk anvendelse derav
TW200633716A (en) Compositions and methods for stabilizing active pharmaceutical ingredients
ATE286500T1 (de) 1,2,3,4-tetrahydroisochinolin-derivate
BG66084B1 (bg) Циклопентаноиндоли, състави,съдържащи такива съединения и използването им
CY1113462T1 (el) Μορφη δοσολογιας περιεχουσα παντοπραζολη ως δραστικο συστατικο
CY1111470T1 (el) Νεες φαρμακευτικες συνθεσεις που περιεχουν φλιβανσερινη πολυμορφη α
DE602005021770D1 (de) Indol-1-yl-essigsäurederivate
TW200514772A (en) Novel tetrahydropyridine derivatives
DE60232880D1 (de) Gpe-analoga und peptidomimetika
MXPA05008960A (es) Oxazolidinonas de indolona antibacteriales, intermedios para su preparacion y composiciones farmaceuticas que las contienen.
SE0303480D0 (sv) Benzofuranes
MEP34308A (en) Oral formulations of cladribine
DE602004019528D1 (de) Usammensetzungen zur behandlung rekurrenten aphthen in der mundhöhle
ATE253359T1 (de) Antithrombotische mittel
TNSN06012A1 (en) Emulsifying systems containing azetidine derivatives
MXPA03008801A (es) Aril oxima-piperazinas utiles como antagonistas de ccr5.
TW200503785A (en) Dosage form containing (S)-pantoprazole as active ingredient
MXPA06000636A (es) Formulaciones semi-solidas para la administracion oral de taxoides.
EA200601015A1 (ru) Пероральные композиции дезоксипеганина и их применение
SE0203817D0 (sv) New composition
MY142077A (en) Semi-solid systems containing azetidine derivatives

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties