ATE483017T1 - Transgenese in säugetieren durch intracytoplasmatische injektion von spermien - Google Patents

Transgenese in säugetieren durch intracytoplasmatische injektion von spermien

Info

Publication number
ATE483017T1
ATE483017T1 AT99941019T AT99941019T ATE483017T1 AT E483017 T1 ATE483017 T1 AT E483017T1 AT 99941019 T AT99941019 T AT 99941019T AT 99941019 T AT99941019 T AT 99941019T AT E483017 T1 ATE483017 T1 AT E483017T1
Authority
AT
Austria
Prior art keywords
sperm
coinjection
transgene
intracytoplasmatic
transgenesis
Prior art date
Application number
AT99941019T
Other languages
English (en)
Inventor
Ryuzo Yanagimachi
Original Assignee
Univ Hawaii
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Hawaii filed Critical Univ Hawaii
Application granted granted Critical
Publication of ATE483017T1 publication Critical patent/ATE483017T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/033—Rearing or breeding invertebrates; New breeds of invertebrates
    • A01K67/0333—Genetically modified invertebrates, e.g. transgenic, polyploid
    • A01K67/0335—Genetically modified worms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/033—Rearing or breeding invertebrates; New breeds of invertebrates
    • A01K67/0333—Genetically modified invertebrates, e.g. transgenic, polyploid
    • A01K67/0337—Genetically modified Arthropods
    • A01K67/0338—Genetically modified Crustaceans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/89—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microinjection
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Animal Husbandry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT99941019T 1998-08-11 1999-08-10 Transgenese in säugetieren durch intracytoplasmatische injektion von spermien ATE483017T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9607898P 1998-08-11 1998-08-11
US13397099P 1999-05-13 1999-05-13
PCT/US1999/018118 WO2000009674A1 (en) 1998-08-11 1999-08-10 Mammalian transgenesis by intracytoplasmic sperm injection

Publications (1)

Publication Number Publication Date
ATE483017T1 true ATE483017T1 (de) 2010-10-15

Family

ID=26791039

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99941019T ATE483017T1 (de) 1998-08-11 1999-08-10 Transgenese in säugetieren durch intracytoplasmatische injektion von spermien

Country Status (16)

Country Link
US (1) US6376743B1 (de)
EP (1) EP1105469B1 (de)
JP (1) JP3830760B2 (de)
CN (1) CN1334870A (de)
AT (1) ATE483017T1 (de)
AU (1) AU772190B2 (de)
BR (1) BR9913643A (de)
CA (1) CA2340199A1 (de)
DE (1) DE69942804D1 (de)
DK (1) DK1105469T3 (de)
HK (1) HK1044174A1 (de)
IL (1) IL141309A0 (de)
MX (1) MXPA01001389A (de)
NZ (1) NZ509634A (de)
RU (1) RU2267270C2 (de)
WO (1) WO2000009674A1 (de)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030079240A1 (en) * 1997-12-18 2003-04-24 Newman Stuart A. Chimeric embryos and animals containing human cells
US7241617B2 (en) * 1998-07-03 2007-07-10 Dnavec Research, Inc. Sendai viral vectors comprising foreign genes inserted between the R1 and R2 Loci
US20040088748A1 (en) * 1999-05-13 2004-05-06 Perry Anthony C.F. Method of performing transgenesis
EP1241935A2 (de) * 1999-12-17 2002-09-25 Gerald Schatten Verfahren zur erzeugung transgener tiere
US20020045156A1 (en) * 2000-05-16 2002-04-18 Mehmet Toner Microinjection of cryoprotectants for preservation of cells
US7094601B2 (en) * 2000-05-16 2006-08-22 The General Hospital Corporation Microinjection of cryoprotectants for preservation of cells
US20040040051A1 (en) * 2001-01-19 2004-02-26 Whitehead Institute For Biomedical Research Generation of non-human mammals by nuclear cloning
US20020116732A1 (en) * 2001-02-13 2002-08-22 Leandro Christmann Microinjection assembly and methods for microinjecting and reimplanting avian eggs
US20080124787A1 (en) * 2001-02-13 2008-05-29 Avigenics, Inc. Microinjection devices and methods of use
US7339090B2 (en) 2001-02-13 2008-03-04 Avigenics, Inc. Microinjection devices and methods of use
US7550650B2 (en) 2001-09-18 2009-06-23 Synageva Biopharma Corp. Production of a transgenic avian by cytoplasmic injection
AU2002341746A1 (en) 2001-09-18 2003-04-01 Avigenics, Inc. Production of a transgenic avian by cytoplasmic injection
US20040210955A1 (en) * 2001-10-26 2004-10-21 Hidenori Akutsu Preparation of spermatozoa for ICSI-mediated transgenesis and methods of using the same
US20040006157A1 (en) * 2002-04-26 2004-01-08 Gloster Daniel F. Ultra violet curable 100 percent solids inks
US20040172667A1 (en) * 2002-06-26 2004-09-02 Cooper Richard K. Administration of transposon-based vectors to reproductive organs
US20040235011A1 (en) * 2002-06-26 2004-11-25 Cooper Richard K. Production of multimeric proteins
US7527966B2 (en) * 2002-06-26 2009-05-05 Transgenrx, Inc. Gene regulation in transgenic animals using a transposon-based vector
WO2005062881A2 (en) 2003-12-24 2005-07-14 Transgenrx, Inc. Gene therapy using transposon-based vectors
CA2557426A1 (en) 2004-02-24 2005-10-06 Thomas W. Hodge Rab9a, rab11a, and modulators thereof related to infectious disease
ES2245591B1 (es) * 2004-04-06 2007-04-01 Consejo Sup. Investigaciones Cientificas Nuevo procedimiento para generar animales transgenicos no humanos, y los animales transgenicos asi obtenidos.
US20060294606A1 (en) * 2004-05-18 2006-12-28 Istefo Moisyadi Tn5 transposase-mediated transgenesis
ES2679282T3 (es) 2004-10-22 2018-08-23 Revivicor Inc. Porcinos transgénicos que carecen de cadena ligera de inmunoglobulina endógena
EP2311530A2 (de) 2004-10-27 2011-04-20 Vanderbilt University An infektionen beteiligte Säugergene
EP3138403A1 (de) 2005-08-09 2017-03-08 Revivicor, Inc. Ctla4-ig exprimierende transgene huftiere und verwendungen davon
US20100272706A1 (en) 2007-06-22 2010-10-28 Jason Mercer Antivirals
WO2010036979A2 (en) * 2008-09-25 2010-04-01 Transgenrx, Inc. Novel vectors for production of interferon
WO2010036978A2 (en) * 2008-09-25 2010-04-01 Transgenrx, Inc. Novel vectors for production of growth hormone
WO2010036976A2 (en) * 2008-09-25 2010-04-01 Transgenrx, Inc. Novel vectors for production of antibodies
ES2548377T3 (es) 2008-10-27 2015-10-16 Revivicor, Inc. Ungulados inmunodeprimidos
US9150881B2 (en) * 2009-04-09 2015-10-06 Proteovec Holding, L.L.C. Production of proteins using transposon-based vectors
US20110038852A1 (en) * 2009-06-10 2011-02-17 3-V Biosciences, Inc. Antivirals that target transporters, carriers, and ion channels
US10202615B2 (en) 2010-12-10 2019-02-12 Vanderbilt University Mammalian genes involved in toxicity and infection
CN104774871A (zh) 2011-02-14 2015-07-15 雷维维科公司 用于血管化异种移植物及其衍生物的异种移植的遗传修饰的猪
US20150025306A1 (en) * 2013-07-19 2015-01-22 Elwha Llc Methods and Systems for Utilizing Sperm for Molecular Delivery
US20150024497A1 (en) * 2013-07-19 2015-01-22 Elwha Llc Methods and Systems for Utilizing Sperm for Molecular Delivery
RU2613788C1 (ru) * 2015-12-15 2017-03-21 Федеральное государственное бюджетное учреждение "Научный центр акушерства, гинекологии и перинатологии имени академика В.И. Кулакова" Министерства здравоохранения Российской Федерации Метод биопсии клеток трофобласта при множественных клетках, не участвующих в компактизации на стадии бластоцисты в программах преимплантационного генетического скрининга эмбрионов человека
CA3031252A1 (en) 2016-07-21 2018-01-25 ObsEva S.A. Oxytocin antagonist dosing regimens for promoting embryo implantation and preventing miscarriage
WO2019113743A1 (zh) * 2017-12-11 2019-06-20 清华大学 基因改造方法
KR102036723B1 (ko) 2018-02-09 2019-11-26 재단법인 대구경북과학기술원 세포질내 정자 주입 시스템 및 이를 이용한 정자 주입 방법
CN114667141A (zh) 2019-09-03 2022-06-24 奥布赛瓦股份公司 用于促进胚胎移植和预防流产的催产素拮抗剂给药方案
US20230102503A1 (en) 2020-02-10 2023-03-30 ObsEva S.A. Biomarkers for oxytocin receptor antagonist therapy
WO2023250101A1 (en) 2022-06-22 2023-12-28 Gameto, Inc. Compositions and methods for inducing oocyte maturation
US11744920B1 (en) 2022-08-12 2023-09-05 Gameto, Inc Implant for ovarian decline and methods of manufacturing an implant for ovarian decline
WO2024054644A2 (en) 2022-09-09 2024-03-14 Gameto, Inc. Production and applications of ovarian and uterine organoids

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6641526B1 (en) * 1998-03-20 2003-11-04 University Of Hawaii Development of normal offspring from oocytes injected with freeze-dried spermatozoa
BR9913644A (pt) 1998-08-11 2001-11-20 Anthony C F Perry Método de realização de transgênese

Also Published As

Publication number Publication date
CN1334870A (zh) 2002-02-06
BR9913643A (pt) 2001-09-25
CA2340199A1 (en) 2000-02-24
DE69942804D1 (de) 2010-11-11
RU2267270C2 (ru) 2006-01-10
IL141309A0 (en) 2002-03-10
EP1105469A4 (de) 2004-03-10
EP1105469B1 (de) 2010-09-29
HK1044174A1 (zh) 2002-10-11
JP3830760B2 (ja) 2006-10-11
AU772190B2 (en) 2004-04-08
AU5475299A (en) 2000-03-06
MXPA01001389A (es) 2004-01-29
US6376743B1 (en) 2002-04-23
EP1105469A1 (de) 2001-06-13
WO2000009674A1 (en) 2000-02-24
DK1105469T3 (da) 2010-12-20
JP2003521868A (ja) 2003-07-22
NZ509634A (en) 2003-10-31

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