ATE482957T1 - Arylessigsäure- und esterderivate und deren verwendung als entzündungshemmende mittel - Google Patents

Arylessigsäure- und esterderivate und deren verwendung als entzündungshemmende mittel

Info

Publication number
ATE482957T1
ATE482957T1 AT06819000T AT06819000T ATE482957T1 AT E482957 T1 ATE482957 T1 AT E482957T1 AT 06819000 T AT06819000 T AT 06819000T AT 06819000 T AT06819000 T AT 06819000T AT E482957 T1 ATE482957 T1 AT E482957T1
Authority
AT
Austria
Prior art keywords
arylestic
acid
inflammatory agents
ester derivatives
derivatives
Prior art date
Application number
AT06819000T
Other languages
English (en)
Inventor
Lyndon Nigel Brown
Catherine Leblanc
David Andrew Sandham
Harinder Pal Singh
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of ATE482957T1 publication Critical patent/ATE482957T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT06819000T 2005-12-09 2006-12-07 Arylessigsäure- und esterderivate und deren verwendung als entzündungshemmende mittel ATE482957T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0525144.2A GB0525144D0 (en) 2005-12-09 2005-12-09 Organic compounds
PCT/EP2006/011770 WO2007065683A1 (en) 2005-12-09 2006-12-07 Aryl acetic acid and ester derivatives and their uses as antiinflammatory

Publications (1)

Publication Number Publication Date
ATE482957T1 true ATE482957T1 (de) 2010-10-15

Family

ID=35735863

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06819000T ATE482957T1 (de) 2005-12-09 2006-12-07 Arylessigsäure- und esterderivate und deren verwendung als entzündungshemmende mittel

Country Status (17)

Country Link
US (1) US20080312229A1 (de)
EP (1) EP1960398B1 (de)
JP (1) JP2009518343A (de)
KR (1) KR20080065699A (de)
CN (1) CN101326185A (de)
AR (1) AR056887A1 (de)
AT (1) ATE482957T1 (de)
AU (1) AU2006322206B2 (de)
BR (1) BRPI0619529A2 (de)
CA (1) CA2630611A1 (de)
DE (1) DE602006017256D1 (de)
GB (1) GB0525144D0 (de)
PE (1) PE20071035A1 (de)
PT (1) PT1960398E (de)
RU (1) RU2008127439A (de)
TW (1) TW200732337A (de)
WO (1) WO2007065683A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY144903A (en) * 2004-06-17 2011-11-30 Novartis Ag Pyrrolopyridine derivatives and their use as crth2 antagonists
GB0525143D0 (en) * 2005-12-09 2006-01-18 Novartis Ag Organic compounds
AU2007282949B8 (en) 2006-08-07 2012-10-04 Actelion Pharmaceuticals Ltd. (3-Amino-1,2,3,4-tetrahydro-9H-carbazol-9-yl)-acetic acid derivatives
US8563573B2 (en) 2007-11-02 2013-10-22 Vertex Pharmaceuticals Incorporated Azaindole derivatives as CFTR modulators
WO2009093029A1 (en) * 2008-01-22 2009-07-30 Oxagen Limited Compounds having crth2 antagonist activity
AP3360A (en) * 2010-01-27 2015-07-31 Boehringer Ingelheim Int Pyrazole compounds as CRTH2 antagonists
TWI562987B (en) 2010-03-22 2016-12-21 Actelion Pharmaceuticals Ltd 3-(heteroaryl-amino)-1,2,3,4-tetrahydro-9h-carbazole derivatives and their use as prostaglandin d2 receptor modulators
US8802868B2 (en) 2010-03-25 2014-08-12 Vertex Pharmaceuticals Incorporated Solid forms of (R)-1(2,2-difluorobenzo[D][1,3]dioxo1-5-yl)-N-(1-(2,3-dihydroxypropyl-6-fluoro-2-(1-hydroxy-2-methylpropan2-yl)-1H-Indol-5-yl)-Cyclopropanecarboxamide
KR101984225B1 (ko) 2010-04-22 2019-05-30 버텍스 파마슈티칼스 인코포레이티드 시클로알킬카르복스아미도-인돌 화합물의 제조 방법
EP2457900A1 (de) 2010-11-25 2012-05-30 Almirall, S.A. Neue Pyrazolderivate mit CRTH2-antagonistischem Verhalten
EP2697223B1 (de) 2011-04-14 2016-07-13 Actelion Pharmaceuticals Ltd. 7-(heteroaryl-amino-)6,7,8,9-tetrahydropyrido-[1,2-a-]indol-essigsäure-derivate und ihre verwendung als prostaglandin-d2-rezeptor-modulatoren
CN103958466B (zh) * 2011-11-17 2015-11-25 山东亨利医药科技有限责任公司 作为crth2拮抗剂的含氮并环化合物
PL3119779T3 (pl) 2014-03-17 2019-01-31 Idorsia Pharmaceuticals Ltd Pochodne kwasu azaindolooctowego i ich zastosowanie jako modulatorów receptora prostaglandyny d2
JP6484644B2 (ja) 2014-03-18 2019-03-13 イドーシア ファーマシューティカルズ リミテッドＩｄｏｒｓｉａ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ アザインドール酢酸誘導体及びプロスタグランジンｄ２受容体調節剤としてのそれらの使用
PT3925607T (pt) 2014-04-15 2023-09-26 Vertex Pharma Composições farmacêuticas para o tratamento de doenças mediadas pelo regulador de condutância transmembranar da fibrose quística
MX2018003202A (es) 2015-09-15 2018-06-08 Idorsia Pharmaceuticals Ltd Formas cristalinas.
AU2018360766A1 (en) 2017-11-06 2020-05-21 Rapt Therapeutics, Inc. Anticancer agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3320268A (en) * 1964-08-14 1967-05-16 Merck & Co Inc 1-aroyl or heteroaroyl-7-azaindole-3-carboxylates and derivatives
HUE026285T2 (en) * 2003-02-06 2016-05-30 Dompe Farm Spa 2-arylacetic acid compounds and their derivatives and pharmaceutical compositions containing them
MY144903A (en) * 2004-06-17 2011-11-30 Novartis Ag Pyrrolopyridine derivatives and their use as crth2 antagonists

Also Published As

Publication number Publication date
CN101326185A (zh) 2008-12-17
AR056887A1 (es) 2007-10-31
JP2009518343A (ja) 2009-05-07
DE602006017256D1 (de) 2010-11-11
US20080312229A1 (en) 2008-12-18
AU2006322206A1 (en) 2007-06-14
TW200732337A (en) 2007-09-01
WO2007065683A1 (en) 2007-06-14
PE20071035A1 (es) 2007-10-30
CA2630611A1 (en) 2007-06-14
EP1960398A1 (de) 2008-08-27
EP1960398B1 (de) 2010-09-29
PT1960398E (pt) 2010-11-26
BRPI0619529A2 (pt) 2011-10-04
GB0525144D0 (en) 2006-01-18
AU2006322206B2 (en) 2010-08-19
KR20080065699A (ko) 2008-07-14
RU2008127439A (ru) 2010-01-20

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