ATE480238T1 - Analoge des 5(e)bromovinyluracils und verwandte pyrimidinnucleoside als antivirale mittel und verwendungsmethoden - Google Patents

Analoge des 5(e)bromovinyluracils und verwandte pyrimidinnucleoside als antivirale mittel und verwendungsmethoden

Info

Publication number
ATE480238T1
ATE480238T1 AT00948851T AT00948851T ATE480238T1 AT E480238 T1 ATE480238 T1 AT E480238T1 AT 00948851 T AT00948851 T AT 00948851T AT 00948851 T AT00948851 T AT 00948851T AT E480238 T1 ATE480238 T1 AT E480238T1
Authority
AT
Austria
Prior art keywords
bromovinyluracil
analogue
methods
antiviral agents
pyrimidine nucleosides
Prior art date
Application number
AT00948851T
Other languages
English (en)
Inventor
Yung-Chi Cheng
Chung Chu
Ling Li
Yongseok Choi
Original Assignee
Univ Yale
Univ Georgia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Yale, Univ Georgia filed Critical Univ Yale
Application granted granted Critical
Publication of ATE480238T1 publication Critical patent/ATE480238T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT00948851T 1999-07-21 2000-07-20 Analoge des 5(e)bromovinyluracils und verwandte pyrimidinnucleoside als antivirale mittel und verwendungsmethoden ATE480238T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/358,028 US6653318B1 (en) 1999-07-21 1999-07-21 5-(E)-Bromovinyl uracil analogues and related pyrimidine nucleosides as anti-viral agents and methods of use
PCT/US2000/019881 WO2001006986A2 (en) 1999-07-21 2000-07-20 5-(e)-bromovinyl uracil analogues and related pyrimidine nucleosides as anti-viral agents and methods of use

Publications (1)

Publication Number Publication Date
ATE480238T1 true ATE480238T1 (de) 2010-09-15

Family

ID=23408010

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00948851T ATE480238T1 (de) 1999-07-21 2000-07-20 Analoge des 5(e)bromovinyluracils und verwandte pyrimidinnucleoside als antivirale mittel und verwendungsmethoden

Country Status (8)

Country Link
US (2) US6653318B1 (de)
EP (1) EP1204415B1 (de)
CN (1) CN1420773A (de)
AT (1) ATE480238T1 (de)
AU (1) AU767676B2 (de)
CA (1) CA2378370C (de)
DE (1) DE60044937D1 (de)
WO (1) WO2001006986A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE269081T1 (de) * 1999-09-24 2004-07-15 Shire Biochem Inc Dioxolan nukleosidanalogen zur behandlung und vorbeugung von viralen infektionen
WO2001032153A2 (en) 1999-11-04 2001-05-10 Shire Biochem Inc. Method for the treatment or prevention of flaviviridae viral infection using nucleoside analogues
JP4651942B2 (ja) * 2001-12-20 2011-03-16 フアーマセツト・インコーポレイテッド Ｅｂｖ及びｋｈｓｖ感染並びにそれに伴う異常細胞増殖の治療
CN101066987B (zh) * 2007-06-14 2010-05-19 上海交通大学 溴呋啶的制备方法
WO2012051492A2 (en) * 2010-10-14 2012-04-19 University Of Georgia Research Foundation, Inc. Compounds and methods for inhibiting hiv latency
CN102649788B (zh) * 2011-02-28 2015-03-25 四川大学 β-L-2’-脱氧-胸腺嘧啶核苷衍生物及其制备方法和用途
CN118176201B (zh) 2021-10-29 2025-09-26 佐治亚大学研究基金会 L-bhdu的前药和治疗病毒感染的方法

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Also Published As

Publication number Publication date
AU767676B2 (en) 2003-11-20
EP1204415A4 (de) 2002-09-04
EP1204415A2 (de) 2002-05-15
DE60044937D1 (de) 2010-10-21
US6653318B1 (en) 2003-11-25
US20040053891A1 (en) 2004-03-18
CA2378370A1 (en) 2001-02-01
WO2001006986A3 (en) 2001-10-25
CA2378370C (en) 2010-01-26
AU6228800A (en) 2001-02-13
WO2001006986A2 (en) 2001-02-01
CN1420773A (zh) 2003-05-28
EP1204415B1 (de) 2010-09-08

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